Toxoplasmosis Abortion in sheep What is Toxoplasmosis ? Toxoplasmosis is caused by a parasite called Toxoplasma gondii. It results in abortion and barrenness in ewes and as such can have a large economic impact. How do sheep become infected? Cats become infected by eating raw tissue containing the cysts. The Toxoplasma then multiplies in the cat’s guts to produce millions of eggs that can contaminate food stores, pasture and water supplies. The eggs can persist in the environment in this way for months or years depending on local conditions such as moisture and temperature. The key source of infection for sheep is eggs in food and water and the key source of infection for cats is tissue cysts in rodents such as mice and in small birds. Infection before pregnancy If the sheep becomes infected before she is pregnant they suffer a passing fever that is not usually noticed by the farmer. After this infection they will develop a solid immunity and will be effectively protected from Toxoplasmosis in the future. However if the ewe becomes infected whilst pregnant the consequences can be very serious for the developing lambs Infection in early or mid pregnancy If infection occurs in early pregnancy then the likely outcome is death of the lamb. If this occurs very early then the lamb may be reabsorbed and the ewe will either return to service or may remain barren. If lamb death occurs later in pregnancy the dead lamb or lambs will be aborted usually a few days before the expected lambing date. Infection in late pregnancy Infection in late pregnancy is less likely to be fatal to the lambs as their ability to fight infection improves as they develop, however they may still die and be aborted or stillborn. Lambs that survive the infection may be weak at birth or die in the first few days of life. It is not unusual for ewes to produce one dead lamb alongside one or more live lambs. The dead lamb may be small or mummified. Ewes that become infected during pregnancy also develop a solid immunity and therefore animals that have aborted once to toxoplasmosis are very unlikely to do so again. Diagnosis of Toxoplasmosis The best way to diagnose the infection is to submit the dead lambs plus the placenta (cleaning) to the VLA centre after speaking with ourselves. Tests to look to antibodies can be done on blood samples from aborted ewes. This again should be discussed with ourselves. There is often a subsidised testing scheme sponsored by one of the vaccine companies. Vaccination The most effective way to protect sheep is to vaccinate them. The vaccine Toxovax gives a life-long immunity with one vaccination. Replacement ewes can be vaccinated from 5 months of age and non-pregnant healthy ewes can be vaccinated at any time apart from the 4-week period before tupping. DO NOT VACCINATE PREGNANT SHEEP. Toxovax is a live vaccine, which is fragile, so needs care when handling it and should not be administered by susceptible people (pregnant women or immunocompromised people). Drug Therapy Significant lamb losses due to toxoplasmosis may be reduced by feeding the coccidiostat decoquinate (Deccox) during pregnancy. It should be added to the feed to provide 2mg/kg bodyweight/day from mid pregnancy. It is most effective if it is already being fed to susceptible ewes at the time the encounter the infection rather than after infection is established. This should be discussed with ourselves before being used. However this is usually a more expensive option than vaccination. As always, please contact ourselves for advice and information.