Curriculum vitae Peter Hamar, MD, PhD, Dsc, Med habil Associate professor Address Semmelweis University, Faculty of General Medicine, Institute of Pathophysiology, Immunopathophysiology laboratory http://semmelweis.hu/immun-patofiziologia/en/ H-1089 Budapest, Nagyvárad tér 4 mobile:+36(20)825-9751 e-mail: hampet@net.sote.hu Education 1996-2001 Specialization in Clinical laboratory Medicine / Imre Hajnal University, Budapest, Hungary 1994-1999 Ph.D. training in nephrology / Semmelweis University, Budapest, Hungary 1989-1994 medical school / Semmelweis University, Budapest, Hungary 1987–1988 premedical school / Rutgers University, New Brunswick, NJ, USA Fellowships 2014 (march-aug) visiting professor – Immune Disease Institute / Harvard Medical School, Boston, MA, USA (Fulbright scholarship) – Prof Dr Judy Liebermann 2003 Invited postdoctoral fellow / CBR Research Institute / Harvard Medical School, Boston, MA, USA (sponsored by PI) – Prof Dr Judy Liebermann 2002, 2003 Invited postdoctoral fellow / University Clinic Heidelberg, Germany – (DAAD reinvitation) - Prof Dr HcMult. Eberhard Ritz 1995-1996 Ph.D. training (visiting fellow) / University Clinic Essen, Germany (DAAD scholarship) – PD Dr Uwe Heemann Qualifications / Degrees 2011 Doctor of sciences (Dsc) – Hungarian Academy of Science (HAS 5019/2011) 2009 Habilitation – Semmelweis University (275/2009) 2001 Specialization in Clinical Laboratory Diagnostics (812/2001) – HIETE University 1999 PhD (262/1999) – Semmelweis University 1994 Medical University: MD (119/1994) – Semmelweis University Languages English: fluent (TOFL score: 588 - 1986), Hungarian State Language Proficiency Diploma: top level - 1988) German: fluent (Hungarian State Language Proficiency Diploma: intermediate level 1994) 10 most important publications: 1 Hamar P, Song E, Short interfering RNA targeting Kökény G, Chen A, Fas protects mice against renal Ouyang N, Lieberman J: ischemia-reperfusion injury 2 Kaucsár T, Révész Cs, Godó M, Krenács T, Albert M, Szaly Cs, Rosivall L, Benyó Z, Bátkai S, Thum T, Szénási G, Hamar P 3 Kaucsár T, Rácz Zs, Hamar P 4 Kaucsár T, Bodor C, Godó M, Szalay C, Révész C, Németh Z, Mózes M, Szénási G, Rosivall L, Sőti C, Hamar P. 5 Buday A, Őrsy P, Godó M, Mózes M, Kökény G, Lacza Zs, Koller A, Ungvári Z, Gross ML, Benyó Z, Hamar P 6 Kökény G, Németh Z, Godó M, Hamar P 7 Németh Z, Kökény G, Godo M, Mózes M, Rosivall L, Groß ML, Ritz E, Hamar P 10,45 Activation of the miR-17 family Nucl Ac Ther and miR-21 during murine kidney ischemia-reperfusion injury 2013. Oct;23(5):34 4-54. Post-transcriptional geneAdv Drug expression regulation by micro Delivery Rev RNA (miRNA) network in renal disease LPS-induced delayed PLoS One preconditioning is mediated by Hsp90 and involves the heat shock response in mouse kidney. 2010 30: 1390-401. 11,96 2014 19;9: e92004 3.73 Elevated systemic TGF-beta impairs aortic vasomotor function through activation of NADPH oxidase driven superoxide production and leads to hypertension, myocardial remodeling and increased plaque formation in apoE-/- mice. The Rowett rat strain is resistant to renal fibrosis Am J Physiol Heart Circ Physiol 2010 299: H386-95. 3,64 Nephrol Dial Transpl 2010 25:1458-62 3,57 Increased renoprotection with ACE inhibitor plus aldosterone antagonist as compared to monotherapies - the effect on podocytes Metabolic factors have a major impact on kidney allograft survival. Nephrol Dial Transpl 2009 (12): 3640-51. 3,57 8 Hamar P, Müller V, Kohnle M, Witzke O, Albrecht KH, Philipp Th, Heemann U: 9 Hamar P, Liu S, Viklický Cyclosporine A and Azathioprine O, Szabó A, Müller V, are equipotent in chronic kidney Heemann U: allograft rejection 10 Hamar P, Lipták P, Heemann U, Iványi B P Natl Acad Sci 2004 101: USA 14883– 14888 Ultrastructural analysis of the fisher to lewis rat model of chronic allograft nephropathy 2.8 Transplantation 1997 64: 1135-9 3,44 Transplantation 2000 69: 1290-5 4,03 2005 18: 863-870 1,8 Transplant Int Grant support (past 10 years) Title Micro-RNAs and parenchymal and glomerular fibrosis of the kidney: ischemia-reperfusion induced fibrosis and FSGS Time period. 20142018 Support Source Reg. nr. 30 M HUF OTKA-FWF K 110810 The regulatory role of micro RNA networks in acute renal failure 20102014 22 M HUF OTKA K 81972 The regulatory role of micro RNA networks in acute renal failure 20092011 3 M HUF ETT 07-011 The role of TGF-beta and its intracellular signaling in uremic atherosclerosis The role of lymphangioneogenesis in chronic allograft nephropathy Combined aldosteron and RAS inhibition in 5/6 nephrectomy induced renal fibrosis ,,Einfluß der kombinierten Blockade von RAS und Mineralkortikoid Rezeptor auf die Progression am Modell der subtotalen Nephrektomie " 20082010 20072008 20072008 20062008 18 M HUF OTKA 0.3 M HUF + 4800 EUR 0.3 M HUF + 12350 EUR 41 000 EUR OMFB/Tet ÖAD OMFB/Tet DAAD Else KrönerFresenius Stiftung NF 69278 HU/08/20 07 D/06/058 60 P50/05// A64/05// F01 RNAi to limit kidney ischemia/reperfusion injury 20052008 90 000 USD Fogarty International R03 TW0070 69-01A1 RNAi to limit kidney ischemia/reperfusion injury Limiting ischemia/reperfusion injury of the kidney utilizing siRNA mediated gene silencing. 20052009 20052006 11 M HUF OTKA T049022 400 000 HUF + 160 000 RMB OMFB/Tet China bilateral CHN37/04 The influence of pregnancy on the progression of systemic autoimmune disease in MRL/lpr mice Equipment grant for implantable telemetric device The role of cytotoxic T-lymphocytes and FAS mediated apoptosis in kidney graft rejection, lupus nephritis and circulatory shock The role of cytotoxic T-lymphocytes and FAS mediated apoptosis in kidney graft rejection, lupus nephritis and circulatory shock Educational grant for implantable telemetric physiological monitoring 20042005 329 e HUF + 11 338 Euro OMFB/Tet DAAD D-6 2004 15 000 Euro 2004 765 000 HUF DAAD Equipment OMFB/Tet – China bilateral CHN10/03 20032005 6 M HUF ETT 432/2003 2003 20 000 USD Data Sciences International DSI-TAG Honors Hungarian 2010 Semmelweis University – Distinction for excellence in research 2010 Sanofi-Aventis/Chinoin Hungarian Research Price: The role of the immune system in the development of chronic renal failure 2009, 2002 Gedeon Richter research award, by: Gedeon Richter Co 2009, 2001, 1999 outstanding achievement, by: Bolyai Grant Committee 2005, 2003, 2000 Young investigator award, by: Hungarian Physiological Society 2005 best international publication, by: Hungarian Nephrological Society 2002 László Hársing award, by: Hungarian Kidney Foundation 2002 Antal Babics award, by: Semmelweis University 1997 best congress presentation: first place, by: Hungarian Nephrological Society 1993 first place, by: Semmelweis University, Scientific Congress of Students International 2001 young investigator award, International Nephrological Society (ISN) 1997 best abstract young investigator, European Dialysis and Transplant Association (EDTA) 1997 best poster young investigator, European Society of Organ Transplantation (ESOT) Roles in the scientific community Regular referee for > 30 international journals including Kidney International, American Journal of Transplantation, British Journal of Cancer, Plos One. 2012, 2014 – Korányi Scientific Committee (head of the evaluator committee) 2011 – Tempus – scientific grants (evaluator) 2010 – National Science and Technology Office (NKTH) – scientific grants (evaluator) 2009 – EURECAM : European Renal and Cardiology Working Group member 2007 – Hungarian Research Fund (OTKA) – research grants (evaluator) 2010-12 Hungarian Research Fund (OTKA) (KISOR committee member) 2007 – Welcome Trust – research grants (evaluator) 2006 – 2009 Asboth program/DermaATS project (scientific advisor) 2006 – Semmelweis University - Students Scientific Congress (TDK) (evaluator) 2006 Croatian Ministry of Sciences - Scientific Grants (evaluator) 2004 – Gerson Lehrmann Consulting Group (New York, NY, USA) (consultant) 2003 Novartis: Allergy and Inflammation contest (evaluator) 1999 Korányi Scientific Committee (evaluator) Scientific Society Memberships 2006 - Hungarian Physiologic Society (MÉT) (member of the executive committee), member since 1998 2002 - International Society of Nephrology (ISN) (member) 2002 - 2005 American Association for the Advancement of Science (AAAS) (member) 2000 - European Kidney Research Association (EKRA) (founding member) 1997 - 2001 European Society for Organ Transplantation (ESOT) (member) 1996 - Hungarian Nephrological Society (MNT-MANET) (member)