Research Colloquium Poster Session Summer Research Undergraduate Students August 2, 2007 Location: Durham Outpatient Center West Atrium Lobby Time: 11:00 am – 1:00 pm A reception follows in the Storz Pavilion at 1:30 P.M. Sponsored by: Eppley Institute, Biomedical Research Training Program, and Office of Research and Development POSTER NUMBER 1 2 3 ANESTHESIA “Preoperative, Intraoperative, & Postoperative Pain Perceptions as Reported by Chronic Pain Patients” Kathryn Kersenbrock, Creighton University, Hiba Ahmad, Creighton Univerity, Kiran Napa, Creighton University Franklin Cobos II, M.D. “Predicting Emergence Times from General Anesthesia” Kiran Napa, Creighton University, Hiba Ahmad, Creighton Univerity, Kathryn Kersenbrock, Creighton University Franklin Cobos II, M.D. “Risks Associated with Post-Operative Myocardial Infarction in Patients Undergoing Surgical Procedures at an Academic Medical Center” Kathryn Kersenbrock, Creighton University Sasha Shillcutt, M.D. BIOCHEMISTRY & MOLECULAR BIOLOGY 4 5 6 7 "Probing the Role of the C-terminal Noncatalytic Region of Myotubularin" Kimberly Acker, Concordia University Gregory Taylor, Ph.D. “Comparative Methods of Protein Extraction from Octopus Hot Spring Microbial Mat” Sharlay Butler, Midland Lutheran College Laurey Steinke, Ph.D., Robert F. Ramaley, Ph.D. and Michelle Fontaine, B.S. “Effects of Phosphorylation of the Longest Carboxyl Terminal of Connexin 43” Khristian Harris, Virginia State University Paul Sorgen, Ph.D., Sylvie Chenevas, Ph.D., and Denis Bouvier, Ph.D. “Effects of RUNX3 Over-expresion in Pancreatic Cancer Cells” Brandon Vanhessche, Rockhurst University Surinder K. Batra, Ph.D. and Maneesh Jain, Ph.D. CELLULAR & INTEGRATIVE PHYSIOLOGY 8 9 "Baroreflex Impairment in Streptozotocin Induced Type-1 Diabetic Rats" Richard Akromis, Kansas State University Harold Schultz, Ph.D. "Exercise Training Normalizes Upregulated Angiotensin Converting Enzyme in the Brain of Rabbits with Pacing Induced Chronic Heart Failure" Sumit Kar, Millard North High School Irving H. Zucker, Ph.D. EPPLEY INSTITUTE FOR RESEARCH IN CANCER 10 "Influence of Amyloid Precursor-Like Protein 2 and Invariant Chain on the Cell Surface Expression of Major Histocompatibility Complex Class I Molecules" Austin Ahles, Missouri Southern State University Joyce Solheim, Ph.D. 11 12 13 14 15 16 17 18 19 20 "Maldi-Tof/Tof Mass Spectroscopy To Study Organophosphate Interaction With Plasma Proteins" John Carr, Missouri Southern State University Shi-Jian Ding, Ph.D. and Oksana Lockridge, Ph.D. “Expression and Purification of Tsg101, CT-Tsg101, and UEV Domain of Tsg101 Proteins” Christopher J. Danford, Stanford University Gloria Borgstahl, Ph.D. and Admir Kellezi "Mutagenic Characterization of Human ITPA" Kathryn Spitler, Drake University Elena Stepchenkova, Ph.D. and Youri Pavlov, Ph.D. INTERNAL MEDICINE “Adenosine Receptor(s) Activation is Involved in Epithilial Ciliary Motility” DeAndre Bluitt, University of North Texas Diane Allen-Gipson, Ph.D. and Justin Jarrell, B.S. “Effect Of PPAR-Gamma Agonists On Fgfand Insulin Stimulated ERK1/2 Invascular Smooth Muscle Cells” Anthony Brand, University of Nebraska at Omaha Cyrus Desouza, M.D., Mark Solomon "Mechanism of Prostaglandin D2 Inhibition of Fibroblast Mediated Collagen Gel Contraction" Whitney Ijem, Washington University in St. Louis Steven Rennard, M.D. and Amy Nelson “An Essential Role of Early Growth Response -1 in Alcohol Induced Fatty Liver”. Megan Millea, Xavier University Terrance M. Donohue, Ph.D. "Possible Involvement of MAPK p38 in the Ethanol-induced G2/M Cell Cycle Arrest" Brigitte Pohren, Dahn Clemens, Ph.D. and Katrina Mahon “The Effect of IGF-1 on HBF and HFL Mediated Collagen Gel Contractions” Humaira Qasimyar, University of Nebraska at Omaha Martin Liu, M.D. and Mona Al-mugotir "Alcohol Exposure Attenuates Airway Smooth Muscle Contraction" Chelsea Ruhge, Nebraska Wesleyan University Peter Oldenburg, Ph.D., Todd Wyatt, Ph.D., and Joseph Sisson, M.D. MD/PhD PROGRAM 21 22 "Differentiation of Human Embryonic Stem Cells Toward Hepatocytes" Eric Bonness, University of Nebraska - Lincoln Ira Fox, M.D. Surgery Department “Collagen mRNA Expression in Lung Fibroblasts” Dixon Dorand, University of Alabama at Birmingham Stephen I. Rennard, M.D. Internal Medicine Department 23 24 25 26 27 28 29 30 31 32 “Identification of Transcriptional Targets of NR2E3 Using Chromatin Immunoprecipitation and ChIP on Chip Microarray Analysis” Meghan Gaule, University of Notre Dame Neena B. Haider, Ph.D. Genetics, Cell Biology and Anatomy Department "Control of Progesterone Synthesis: Effects of Metformin and AICAR on Steroidogenic Cells" Lauren Gengenbach, Nebraska Wesleyan University John Davis, Ph.D. and Sharon Hou, M.D. Obstetrics & Gynecology Department “The Interaction Of VASP With IP3R And TRPC Calcium Channels In MDCK Cells” Andy Huss, Rice University Steven Sansom, Ph.D. Cellular and Integrative Physiology Department “Fas-Mediated Apoptosis Regulates Iron Metabolism in Vivo” Chris Jensen, Rice University Dee Harrison-Findik, Ph.D., D.V.M. Internal Medicine Department “Comparison of Transabdominal Ultrasound and Electromagnetic Transponders for Prostate Localization: Clinical Experience in a Large Patient Population” Andrew Kerkhoff, University of North Carolina of Chapel Hill Ryan D. Foster, Ph.D. and Timothy D. Solberg, Ph.D. Radiation Oncology Department “Expression of Mucin Biomarkers in Human Pancreatic Cancer Tissue” Katie Lutz, Iowa State University Tony Hollingsworth, Ph.D. Eppley Research Institute “Glutaminase Release from Damaged Macrophages: A Mechanism for Excitotoxicity in HIV Associated Dementia” Emma Meyer, Carleton College Jialin Zheng, M.D. Pharmacology and Experimental Neuroscience Department “IL-1ß-induced Human Astrocyte Activation Causes Impaired Glutamate Clearance: Mechanistic Links to HIV-Associated Dementia” Crystal Reyelts, Vanderbilt University Wei Kou, M.D., Ph.D. and Anuja Ghorpade, Ph.D. Pharmacology & Experimental Neuroscience Department "The Role Of CTLA4 In The Pathogenesis Of CLL Subgroups" Rae Rohlfsen, Saint Louis University Shantaram S. Joshi, Ph.D. Genetics, Cell Biology, and Anatomy Department “Applications of Mass Spectrometry to the Characterization of Organophosphate Adducts of Proteins” Lawrence Yun Tong, Boston College Oksana Lockridge, Ph.D Eppley Research Institute PEDIATRICS 33 34 35 36 37 38 39 40 41 42 43 “Seasonal Comparison of Vitamin D Levels in Patients with Cystic Fibrosis” Natalie Brooks, Nebraska Wesleyan University Heather Thomas, M.D. "Sjögren-Larsson Syndrome: Large Gene Deletions Detected by Inverse PCR" Holly Engelstad, Iowa State University William Rizzo, M.D. “Histochemical Localization of FALDH in WIld-Tyoe and FALDH Deficient Mouse Tissues” Joseph V. Lamar, University of Nebraska at Omaha William B. Rizzo, M.D. "Adolescent Health Findings: City Data from the 2005 Youth Risk Behavior Surveillance System" Zack Sutton, Creighton University Carol Gilbert, M.S. and Patrick Simpson, M.P.H. PHARMACOLOGY & EXPERIMENTAL NEUROSCIENCE "HIV-1 And Viral Glycoproteins Induce Dysfunction Of Human Brain Endothelium Via The JAK/STAT Signaling Pathway" Sidra Akhter, Millard North High School Georgette Kanmogne, Ph.D. and Sangya Singh “Optimization of a Method for the Purification of the Ryanodine Receptor (RyR2) by GST-FKBP12.6 Affinity Chromatography” Andrew Barnett, Drake University Keshore Bidasee, Ph.D., Chung-Hong Shao, Ph.D., and Xiaoyan Feng “Stimulation of Lung Fibroblasts-Mediated Collagen Gel Contraction by Lysophosphatidic Acid” Stephanie Brady, University of Nebraska at Omaha Myron Toews, Ph.D., Karen Kassel, Ph.D., and Nancy Schulte "Selectivity of NU Drugs for Human Alpha-2B Adrenergic Receptors Over Alpha-2A and Alpha-2B Adrenergic Receptors" Abigail Fitzgerald, Hastings College David Bylund, Ph.D., Jeff Anderson, and Chris Taylor “Creation of an Adeno-Associated Virus to Up-Regulate Glyoxalase I Expression in Diabetic Rats” Jose M. Lopez, University of Texas - Pan American Keshore Bidasee, Ph.D., Chun-Hong Shao, M.D., Ph.D., Tsuneya Ikezu, M.D., Ph.D. and Xiaoyan Feng “A Humanized Mouse Model in the Study of Human Immunodeficiency Virus Type 1 Pathogenesis and Vaccine Response” Aaron Persinger, Nebraska Wesleyan University Howard E. Gendelman, M.D., Larisa Poluektova, M.D.,Ph.D., and Santhi Gorantula, Ph.D. “Macrophage-based Anti-Retroviral Delivery: Implications for HIV-1 Associated Dementia” Ben Robbins, Grand Island Senior High Huanyu Dou, M.D., Cassi Grotepas 44 45 46 “Immunohistochemical Analysis of Tau-Tubulin Kinase 1 and P301L Tau Mutant/Tau-Tubulin Kinase 1 Transgenic Mice” Russell Swan, University of Nebraska-Lincoln, Tsuneya Ikezu, M.D., Ph.D (Presented by Ben Robbins) “Microglia-Astrocyte Crosstalk and the Neuropathogenesis of HIV-1 Infection” Juliet Silberstein, Amherst College Howard Gendelman, M.D. and Tong Wang, Ph.D “Transcription Factor FOXO3a Mediates Apoptosis in Human Neural Progenitor Cells” Marrisa Yang, University of North Texas Jialin Zheng, M.D., Yunlong Huang, M.D., Ph.D. PHARMACEUTICAL SCIENCES 47 48 49 50 51 52 53 54 55 "LHRH-Receptor Targeted Prostate Cancer Therapy" Jennifer Christie, Hampton University Uday Kompella, Ph.D. “The Usefulness of an Ex-Vivo Bovine Eye Model for Examining the Corneal Penetration of Topical Ophthalmic Drugs” Joe Hejkal, University of Dallas Uday Kompella, Ph.D. “Does the Stability of a DNA Duplex Affect the Formation of Its Related Triplex?” Ian Herran, University of Texas Luis Marky Ph.D., Irine Khutsishvili, Ph.D., and Hui-Ting Lee “Folate-Nanogel Mediated Targeting of MGTP to Leukemic Cancer Cells” Jared Knoell, University of Nebraska-Lincoln Serguei V. Vinogradov, Ph.D. "Combinations of 1,2,4-Trioxolanes with Chemotherapeutic Agents" Kiel Neumann, University of Nebraska at Omaha Jonathon L. Vennerstrom, Ph.D., Yuxiang Dong, Ph.D., and Richard Lomneth, Ph.D. "Quantitative Structure Pharmacokinetic Relationships for Intravitreal Drug Clearance" Shruti Senapati, Georgia Institute of Technology Uday B. Kompella, Ph.D. and Chandrasekar Durairaj, Ph.D. “Synthesis of an Antimalarial Trioxolane Containing an Aniline Moiety” Xu (Sherry) Wang, Washington University in St. Louis Jonathan Vennerstrom, Ph.D. “The in vitro Double Targeting of DNA Single Strands Yields Stable Bimolecular Triplexes” Lela Waters, Northwestern University Luis A. Marky, Ph.D. and Hui-Ting Lee “Cytotoxicity and Uptake of Spermine Modified Pluronics and Cancer Therapy Drug, FdUTP, in PC-3 Cell Lines” Brittany Williams, Creighton University Serguei Vinogradov, Ph.D. 56 SURGERY “TGF-â Induced JNK Phosphorylation in Smooth Muscle Cells” Rachel Quinn, Creighton University B. Timothy Baxter, M.D.