Mitosis and Meiosis made Simple. Mitosis and Meiosis Cell Division, Asexual Reproduction, and Mitosis Multicellular living things grow and repair their ___________. Your skin cells are always dying, losing 30 to 40 thousand every minute, and being replaced. We humans lose cells but our epidermis works to make ____________ skin cells to replace the dead cells. Where do new skin cells come from? They are made when existing cells divide to form new cells that are exactly _____________. This process is called cell division. The original cell that divides is called the ________________ cell. The cells formed through cell division are called ______________ cells. In mitosis you obtain ________ genetically identical daughter cells from _________ parent cell. Vocabulary: Homologous - Pairs of chromosomes that have ________________ for the same traits arranged in the same order. The chromosomes may not be identical because each one of the pairs is inherited from a different____________. The father may have the gene for brown hair while the mother might have the gene for blonde hair on the homologous pair of___________________. The genes for hair color from the mother and father would be on the same ___________on the chromosome. ~1~ Sister Chromatids - are two identical halves of a single replicated (copied) ________________ that are connected by an area called a centromere. They are joined at the centromere (see diagram) and are genetically identical. ~2~ A chromosome made up of two sister chromatids held together at the centromere. http://www.macroevolution.net/meiosis-stages.html#.UYAtjWzD-EV Centromere - A centromere is a region on a __________________ that joins two sister chromatids. Diploid cells – Cells that have _____________ of chromosomes. In humans we have 23 pairs of chromosomes for a total of _____ chromosomes. Haploid cells – are cells that have only ______ chromosome from each pair. In humans these would be the ________ and sperm _________ which would have 23 chromosomes each. ~3~ Asexual Reproduction: Asexual reproduction is the reproduction of one cell from one _______________. The process of mitosis is used to produce exact ________________ cells from the parent cell in simple organisms that have a nucleus (eukaryotes). The process called Binary Fission occurs when a simple organism divides in half to make two new_____________. This method occurs in unicellular (one cell) organisms and is the main type of reproduction in the Protista Kingdom. Examples are algae, paramecium, amoeba, and euglena. The parent cell is exactly ____________ or genetically the same as the two new _______________ cells. In the process of binary fission, an organism duplicates its genetic material, or _______________ and then divides into two parts (cytokinesis), with each new organism receiving one ___________ of the chromosomes that carry the DNA. Cytokinesis, in biology, is the process by which one cell physically divides into _______ cells. Another type of asexual reproduction called regeneration occurs when an organism grows from a part of its_____________. The ability to regenerate a new organism varies greatly among animals. An example is some sea __________________ have five arms. If separated from the parent each arm has the potential to ________________into a new starfish if the arm contains a part of the central disc. Like all asexual reproduction, the offspring is genetically _________________to the parent. ~4~ Before a eukaryotic cell (a cell with a true nucleus) divides, the genetic material in the nucleus of the cell _______________itself. When the cell divides, the nuclear material splits in half so that each daughter cell gets genetic material that is the ___________ as that of the parent cell. The dividing of the nuclear material is known as mitosis. In the last stage of cell division, the cytoplasm that makes up the cell also divides. The cytoplasm consists of all of the contents outside of the ________________ and enclosed within the cell membrane of the cell. There are now _____________ complete cells where there used to be one. Cell division is the complete process of dividing the whole ________ called cytokinesis and dividing and copying of the nuclear material called mitosis. A simple explanation of what takes place in Mitosis 1. (Interphase) Before mitosis takes place the cell performs all its normal functions or_____________. Different cells will go through the process of mitosis at different times of their lives depending on what type of ___________ it is. For an example nerve cells may take up to over 60 years before they begin the process of mitosis while ____________ cells may take from 20 to 24 hours. http://www.usatoday.com/videos/news/health/2014/04/08/7452193/ (man walks damaged n) (Interphase part 2) Just before the beginning of mitosis the DNA in the nucleus makes an exact ____________ of itself and the cell replicates its chromosomes. Each chromosome is composed of two sister chromatids containing ~5~ ______________ genetic information. The cell is now ready for mitosis. The process of mitosis usually takes about an hour to complete. Two sister chromatid which is also called a __________________________. 2. (Prophase) Early during prophase, the first stage of mitosis, the chromosomes become visible with a light microscope as they condense (that is, as they shorten, coil, and thicken).The ______________ wall of the cell disappears and the chromosome copies are held together at their centers, so they form a sort of X. The center where the two identical chromatids meet is called the__________________. These chromosomes are called sister chromatids. Also, spindle fibers begins to extend outward from each of the two centrioles. Finally the spinal fibers from both sides of the cell attach themselves to the ____________________ (area where the two _____________________ are attached). ~6~ 3. (Metaphase) The chromosome or sister ____________________ pairs line up single file at the center of the _________. ~7~ 4. (Anaphase) Now, during anaphase, the two sister chromatids of each chromosome are pulled _____________ by the spindle fibers and dragged by their centrosomes toward opposite poles of the _______________. 5. (Telophase) During telophase (pronounced "TEE-low-faze" or "TELL-ə-faze"), the last stage of mitosis, the chromosomes have reached the opposite ends of the ______________ and they begin to uncoil and become less condensed (reversing the process that occurred during prophase. A new nuclear membrane is produced surrounding the _________________. Also cytokinesis occurs during this stage as the cytoplasm pinches in at the center of the cell, dividing the original cell in ________________. Cytokinesis is not a part of ____________ but can start to occur in the last stage of anaphase into the telophase. http://www.macroevolution.net/mitosisanimation.html#.UYfQBV_D8dU – Mitosis video Use to show meiosis go to bottom biological dictionary – look up Meiosis – go to next page at bottom and then go to meiosis animation. ~8~ 6. The cell division is complete two _______________ daughter cells are formed which is identical to the original _______________cell. The two new daughter cells then would grow and carry on their function or __________. In humans you will produce two ________________daughter cells with 46 chromosomes or ______ homologous pairs. Meiosis The beginning of Meiosis is very similar to _____________ with some very important differences. The job of meiosis is to produce 4 daughter cells or gametes (sex cells) with half the number of chromosomes (_______________ number) from one parent cell (____________ number). ~9~ A simple explanation of what takes place in Meiosis Meiosis part 1 (Interphase) This also is not a true step in__________________. Just before the beginning of meiosis the DNA in the nucleus makes an exact ____________ of itself and the cell replicates its chromosomes. Each chromosome is composed of two sister chromatids containing _________________ genetic information. The cell is now ready for meiosis. Steps in Meiosis 1. (Prophase I) Nearly the same as mitosis as the cell wall of the ____________ disappears and homologous chromosomes come together matching gene by____________. The matching homologous chromosomes from the ________________(maternal) and _____________(paternal) pair up. This gives us two chromosomes or two ~ 10 ~ _________________ chromosomes or two pairs of sister ________________ which are paired up. The mothers’ homologous pair and the fathers’ homologous pair have the same _____________ information. Example: eye color - one gene on the chromosome may have a different trait for eye color than the other one or they may have the same trait for eye color. The father may have a gene for the trait of brown eyes while the mother may have the trait for blue eyes or they both might have the gene that would produce blue eyes. The sister chromatids are held together at their centers forming an X; the center is called a centromere. Figure 1 4 chromosomes or two homologous pairs with the beginning of spinal fibers forming from the centrioles. 2. (Prophase I) During this phase the paired up chromosomes or the two pair of sister chromatids from the _____________ and _______________can swap matching sections of the chromosome material called cross over. This process called cross over increases genetic diversity where every chromosome and the two pair of sister chromatids are genetically __________________. No crossing over occurs between two sister chromatids but between the two pair of sister chromatids from the _______________ and _______________. ~ 11 ~ Every gamete or chromosome is genetically different 3. (Metaphase I) The homologous chromosomes or the two pairs of ____________ ______________ line up in pairs along the center of the __________: this is different from mitosis in which the chromatids lined up ______________ file. Then special apparatus called a _______________ fiber organized from centrioles attaches itself to the center of the sister chromatids (_____________________) and during the next phase each pair of sister chromatids are pulled to _______________ sides of the cell. ~ 12 ~ 4. (Anaphase I) Almost the same as in mitosis as the homologous paired chromosomes or sister chromatids ____________ from each other as they move to opposite sides of the cell. The chromosomes or two sister chromatids from the _______________ or ____________ can go to either side of the dividing cell. This is different than mitosis because in mitosis the sister chromatids separate into ________ parts and go to _________________ sides of the cell while in meiosis the sister chromatids do __________ separate. 5. (Telophase I) At each pole, now, there is a complete set of homologous chromosomes (but each chromosome still has sister chromatids).During this stage cytokinesis occurs as the cytoplasm pinches in at the ____________ of the cell, dividing the original cell in______________. The cytoplasm pinches in at the center of the _________ , dividing the original parent ~ 13 ~ cell in ___________ producing two ________________ daughter cells. The sister chromatids or chromosomes do not ________________ but stay attached at the centromeres. Two haploid daughter cells form with different _________________ materials. Meiosis part 2 6. (Prophase II) If a nuclear membrane formed around the chromosomes than the nuclear membrane breaks _____________ but the chromosomes are not copied. Again, the chromosomes are not yet attached to the spindle apparatus, which is growing outward from the centrioles. ~ 14 ~ 7. (Metaphase II) For each daughter cell the homologous chromosomes or sister chromatids again line up in the _____________ of the cell but this time single-file instead of pairs. The ______________ fibers attach themselves to opposite ends of the ________________ of each chromatid. ~ 15 ~ 8. (Anaphase II) During anaphase II the sister chromatids of each chromosome ______________ and move toward ________________ poles. Once they are no longer connected, the former chromatids are called unreplicated chromosomes. One chromosome is pulled to one _____________ of the cell. The other chromosome is pulled to the other side of the cell. 9. (Telophase II) During telophase II, the _________________ reach opposite poles, cytokinesis occurs, the two cells produced by meiosis I divide to form _________ haploid ________________ cells. When the two cells are entirely separated and the ___________ around the chromosomes is fully formed, meiosis will be complete. ~ 16 ~ http://www.macroevolution.net/meiosisanimation.html#.UYfp7WzD-EU Use to show meiosis go to bottom biological dictionary – look up Meiosis – go to next page at bottom and then go to meiosis animation. 10. Four new ________________ cells have formed from the original cell. Each of the four cells has half the number of chromosomes that the original cell had, and therefore only half the amount of ______________ material. Each one of the cells is not exactly __________ but has some different genetic material. It creates diversity which is essential for the development and survival of the species. 11. The final product of meiosis is the production of 4 daughter _________________ sex cells called gametes that are genetically different from one diploid parent cell. The ___________ gametes are called sperm and the ______________ gametes are called eggs. In humans from one diploid cell with _______ chromosomes or ______ homologous pairs produce four daughter cells with __ chromosomes. 12. When a female _______(23 chromosomes - haploid number) is fertilized with a male sperm (_____chromosomes ___________number) the fertilized egg called a zygote will again have the ______________ number of chromosomes 46. ~ 17 ~ Half of chromosomes from the __________ (23) and half the chromosomes (23) from the__________. Each chromosome from each parent has a matching pair called a ________________ pair where the same genes are located for the same characteristics. In humans we have _____ homologous pairs. See Vocabulary. https://www.youtube.com/watc h?v=toWK0fIyFlY great meiosis show cartoon http://www.youtube.com/watch ?v=gwcwSZIfKlM great mitosis show video Above diagram shows the steps in meiosis ~ 18 ~ http://highered.mcgrawhill.com/sites/9834092339/student_view0/chapter29/mitosis.html http://www.youtube.com/watch?v=35ncSrJOwME&feature=related http://highered.mcgrawhill.com/olcweb/cgi/pluginpop.cgi?it=swf::535::535::/sites/dl/free/007 2437316/120074/bio19.swf::Stages%20of%20Meiosis http://sumanasinc.com/webcontent/animations/biology.html http://www.macroevolution.net/prophase-i.html#.UXmbkGzD-EU One used for notes ~ 19 ~ Mitosis and Meiosis Compared It's really important that you don't get meiosis and mitosis confused! Take some time to look at the table below and make sure you understand all the differences between the two types of cell division. Mitosis Meiosis Purpose To make daughter cells _______________ to the To produce sex cells (gametes or parent cells during eggs and sperm) growth, repair, or for asexual reproduction. Location In all cells apart from ________________ In the _____________ organs (ovaries - female and testes- male) Produces how many cells? Two _____________ cells ____________ gametes or daughter cells (sex cells – eggs or sperm cells) Same number as in What happens to _______________ cell number of which is the diploid chromosomes? number. ~ 20 ~ _______________ as many as in parent cell. When you have half of the genetic material and chromosomes it is called a _________________ cell. (The original number of chromosomes is restored when two ________________ fuse to form a zygote which is a fertilized egg cell. This will produce a _________________ cell with genetically matching chromosome from ________ and genetically matching chromosome from _______ called homologous pairs.) Mitosis Meiosis How do parent and daughter cells differ genetically? Not at all - genetic Contain a mixture of chromosomes material is ___________ from two parent gametes - so exactly (replicated) cannot be ___________ Variation between daughter cells? ________ - they are clones of each other ~ 21 ~ ____________ - they are genetically ________________ from each other. ~ 22 ~ ~ 23 ~