Raphael Rosenhek, M.D. Associate Professor Director Clinic for Valvular Heart Disease Department of Cardiology, Medical University Vienna Währinger Gürtel 18-20, A-1090 Vienna, Austria Phone: +43-1-40400-4614; Fax: +43-1-40400-4216 Email: raphael.rosenhek@meduniwien.ac.at Areas of Specialization Valvular Heart Disease, Echocardiography Education MD Faculty of Medicine, University of Vienna 1998 Associate Professor, Cardiology, Medical University of Vienna 2005 Academic Position Director, Clinic for Valvular Heart Disease, Medical University of Vienna since October 2007 Professional Affiliation Member of the Nucleus of the Working Group on Valvular Heart Disease of the European Society of Cardiology (ESC), 2002Treasurer of the Nucleus of the Working Group on Valvular Heart Disease of the European Society of Cardiology (ESC), 2006-2008 Scretary of the Nucleus of the Working Group on Valvular Heart Disease of the European Society of Cardiology (ESC), 2008Editorial Functions Heart: associate editor since july 2006 Medscape Cardiology, contributing editor (since 1999) Member of the Faculty of 1000 Medicine for Cardiovascular Disorders (Section Valvular Heart Disease) 2004-2008 Cardiology: Editorial Board Member since march 2008 Archives of Cardiovascular Diseases: Member of the scientific committee (formerly “Archives des Maladies du Coeur et des vaisseaux”) since January 2008 Awards 1 Advancement Grant of the Medical Faculty of the University of Vienna 1997 for the research work “Differential expression of tissue-type plasminogen activator in the aorta and the pulmonary artery”. 2 Cournand and Comroe Young Investigator Prize in Cardiopulmonary and Critical Care finalist at the 71st Scientific Sessions of the American Heart Association, 1998, Dallas, Texas, USA for the work “Increased fibrinolytic gene expression in pulmonary artery”. 2 Travel grant of the Austrian Society of Cardiology 1999 for the work “The natural history of asymptomatic severe aortic stenosis” presented at the European Society of Cardiology congress 1999, Barcelona, Spain. 3 Poster award (second prize) Austrian Society of Cardioloy congress 2000 for the work “Elective aortic valve replacement in asymptomatic patients with severe aortic stenosis? Selection of high risk patients by echocardiography”, Gmunden. Austria 4 Travel grant of the Austrian Society of Cardiology 2000, for the work “Can Echocardiography Identify Patients With Severe but Asymptomatic Aortic Stenosis Who May Benefit From Elective Surgery” presented at the European Society of Cardiology congress 2000, Amsterdam, Netherlands. 5 Austrian Cardiology award (second prize), Austrian Society of Cardioloy 2001 for the work “Predictors of outcome in severe, asymptomatic aortic stenosis” Linz, Austria. 6 Poster award (third prize) Austrian Society of Cardioloy congress 2003, Vienna, Austria. 7 Travel grant of the Austrian Society of Cardioloy 2003, for the work “Statins but not ACE-inhibitors reduce aortic stenosis progression”, American Heart Association congress 2003, Orlando, USA. 8 Best clinical abstract award, Austrian Society of Cardioloy congress 2004 for the work “Statins but not ACE-inhibitors reduce aortic stenosis progression”, Salzburg, Austria. 9 Young Investigator Award 2004 - Euroecho 8 – Congress for the work “Statins But Not ACE-Inhibitors Slow Aortic Stenosis Progression”. December 2004, Athens, Greece. 10 Austrian Cardiology award (first prize), Austrian Society of Cardioloy 2005 for the work “Statins But Not ACE-Inhibitors Slow Aortic Stenosis Progression”. May 2005, Salzburg, Austria. 11 Award Researcher of the Month – Medical University of Vienna for the work “Statins But Not ACE-Inhibitors Slow Aortic Stenosis Progression”. June 2005, Vienna, Austria. 12 Price for the best postdoctoral lecture qualification 2006 Medical University of Vienna. May 2006, Vienna, Austria. 13 Austrian Cardiology award (first prize), Austrian Society of Cardioloy 2006 for the work „Outcome of watchful waiting in severe but asymptomatic mitral regurgitation“. June 2006, Salzburg, Austria. Publications 1 Rosenhek R, Binder T, Porenta G, Lang I, Christ G, Schemper M, Maurer G, Baumgartner H. „Predictors of outcome in severe, asymptomatic aortic stenosis“ NEW ENGL J MED 2000;343(9):611-7. Editorial: Otto CM. „Aortic stenosis – listen to the patient, look at the valve“ NEW ENGL J MED 2000;343(9):652-4. 2 Binder T, Rosenhek R, Frank H, Gwechenberger M, Maurer G, Baumgartner H. „Congenital malformations of the right atrium and the coronary sinus: an analysis based on 103 cases reported in the literature and two additional cases“ CHEST 2000;117(6):1740-8. 3 Binder TM, Rosenhek R, Porenta G, Maurer G, Baumgartner H. „Improved assessment of mitral valve stenosis by volumetric real-time three-dimensional echocardiography“ J AM COLL CARDIOL 2000;36(4):1355-61. 4 Rosenhek R, Maurer G, Baumgartner H. „Should early elective surgery be performed in patients with severe but asymptomatic aortic stenosis?“ EUR HEART J 2002 Sep;23(18):1417-21. 5 Rosenhek R, Binder T. „Monitoring of invasive procedures – the role of echocardiography in cathlab and operating room“ J CLIN BASIC CARDIOL 2002; 5: 139-43. 6 Rosenhek R, Binder T, Maurer G. „Intraoperative transesophageal echocardiography in valve replacement surgery“ ECHOCARDIOGRAPHY 2002 Nov;19(8):701-7. 7 Rosenhek R, Korschineck I, Gharehbaghi-Schnell E, Jakowitsch J, Bonderman D, Huber K, Czerny M, Schleef RR, Maurer G, Lang IM. „Fibrinolytic balance of the arterial wall: pulmonary artery displays increased fibrinolytic potential compared with aorta“ LAB INVEST 2003;83(6):871-6. 8 Rosenhek R, Binder T, Maurer G, Baumgartner H. “Normal Values for Doppler Echocardiographic Assessment of Heart Valve Prostheses” J AM SOC ECHOCARDIOGR 2003;16(11):1116-27. 9 Rosenhek R, Klaar U, Schemper M, Scholten Ch, Heger M, Gabriel H, Binder Th, Maurer G, Baumgartner H. „Mild and moderate aortic stenosis – natural history and risk stratification by echocardiography“ EUR HEART J 2004;25(3):199-205. Editorial: Otto CM. Aortic stenosis: „even mild disease is significant“ EUR HEART J 2004;25(3):185-187. 10 Bergler-Klein J, Klaar U, Heger M, Rosenhek R, Mundigler G, Gabriel H, Binder T, Pacher R, Maurer G, Baumgartner H. „Natriuretic peptides predict symptom-free survival and postoperative outcome in severe aortic stenosis“ CIRCULATION 2004;109(19):2302-8. 11 Mascherbauer J, Schima H, Rosenhek R, Czerny M, Maurer G, Baumgartner H. „Value and limitations of aortic valve resistance with particular consideration of low flow-low gradient aortic stenosis: an in vitro study“ EUR HEART J 2004;25(9):787-93. 12 Rosenhek R, Rader F, Loho N, Gabriel H, Heger M, Klaar U, Schemper M, Binder T, Maurer G, Baumgartner H. „Statins but not angiotensin-converting enzyme inhibitors delay progression of aortic stenosis“ CIRCULATION 2004;110(10):1291-5. Editorial: Rajamannan NM, Otto CM. Targeted therapy to prevent progression of calcific aortic stenosis. CIRCULATION 2004;110(10):1180-2. 13 Scholten C, Rosenhek R, Binder T, Zhetgruber M, Maurer G, Baumgartner H. “Hand-held miniaturized cardiac ultrasound instruments for rapid and effective bedside diagnosis and patient screening” J EVAL CLIN PRACT 2005;11(1):67-72. 14 Heger M, Willfort A, Neunteufl T, Rosenhek R, Gabriel H, Wollenek G, Wimmer M, Maurer G, Baumgartner H. “Vascular Dysfunction after Coarctation Repair is Related to Age at Surgery” INT J CARDIOL 2005;99(2):295-9. 15 Mascherbauer J, Rosenhek R, Bittner B, Binder J, Simon P, Maurer G, Schima H, Baumgartner H. “Doppler echocardiographic assessment of valvular regurgitation severity by measurement of the vena contracta: an in vitro validation study”. J AM SOC ECHOCARDIOGR 2005;18(10):999-1006. 16 Bergler-Klein J, Klaar U, Heger M, Rosenhek R, Gabriel H, Binder T, Pacher R, Maurer G, Baumgartner H. “Big endothelin-1 is not a predictor in aortic stenosis, but is related to arterial blood pressure” INT J CARDIOL 2006 Nov 10;113(2):174-80. 17 Rosenhek R, Editorial „Statins for Aortic Stenosis“ N ENGL J MED 2005 Jun;352(23):2441-3. 18 Rosenhek R, Rader F, Klaar U, Gabriel H, Krejc M, Kalbeck D, Schemper M, Maurer G, Baumgartner H. „Outcome of watchful waiting in severe but asymptomatic mitral regurgitation“ CIRCULATION 2006;113:2238-44. 19 Rosenhek R, Baumgartner H. „Aortic sclerosis, aortic stenosis and lipid lowering therapy“ EXPERT REV CARDIOVASC THER. 2008 Mar;6(3):385-90. 20 Takkenberg JJ, Rajamannan NM, Rosenhek R, Kumar AS, Carapetis JR, Yacoub MH; Society for Heart Valve Disease. „The need for a global perspective on heart valve disease epidemiology. The SHVD working group on epidemiology of heart valve disease founding statement“ J HEART VALVE DIS. 2008 Jan;17(1):135-9. 21 Mascherbauer J, Rosenhek R, Fuchs C, Pernicka E, Klaar U, Scholten C, Heger M, Wollenek G, Maurer G, Baumgartner H. „Moderate patient-prosthesis mismatch after valve replacement for severe aortic stenosis has no impact on short-term and long-term mortality. Heart. 2008 Dec;94(12):1639-45. 22 Rosenhek R. „Aortic stenosis“ Rev Prat. 2009 Feb 20;59(2):178-81. 23 Zimpfer D, Aharinejad S, Holfeld J, Thomas A, Dumfarth J, Rosenhek R, Czerny M, Schaden W, Gmeiner M, Wolner E, Grimm M. „Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure. “ J Thorac Cardiovasc Surg. 2009 Apr;137(4):963-70. Book Contributions 1 Rosenhek R., Baumgartner H. “Predictors of Outcome in Severe, Asymptomatic Aortic Stenosis” Chapter 52: In Harrison’s Advances in Cardiology. Editor: Eugene Braunwald. McGraw-Hill Publishing, 2003. 2 Rosenhek R, Baumgartner H. „Normal Echocardiographic Data of Prosthetic Valves“ In Management of Patients after Heart Valve Surgery. Editors: Eric Butchart, Christa Gohlke-Bärwolf, Manuel Antunes, Roger Hall. Taylor and Francis Medical Publishing, 2006. 3 Rosenhek R. „Aortic Stenosis: Echocardiographic evaluation of disease severity, disease progression, and the role of echocardiography in clinical decision making.“ In The Practice of Clinical Echocardiography. 3rd edition. Editor: Catherine Otto. W.B. Saunders, 2007. 4 Rosenhek R, Baumgartner H. „Aortic Stenosis“ In Valvular Heart Disease. 3rd edition. Editors: Catherine Otto, Robert Bonow. W.B. Saunders, 2009 (in press). Invited Talks at International Scientific Meetings 1 Natural history and progression of mild aortic stenosis Sesión Clínica General, Hospital General Vall d’Hebron June 6, 2003, Barcelona, Spain 2 Challenging issues in valvular heart disease: applying the guidelines: Asymptomatic moderate aortic stenosis Main session European Society of Cardiology Congress 2003 August 30 – September 3, 2003, Vienna, Austria 3 New aspects of aortic stenosis: Natural history of the asymptomatic patient European Society of Cardiology Congress 2003 August 30 – September 3, 2003, Vienna, Austria 4 Interactive case presentation: Difficult sitations in patients with mechanical valve prosthesis: The patient with high transprosthetic gradient (Focus Session) European Society of Cardiology Congress 2003 August 30 – September 3, 2003, Vienna, Austria 5 Asymptomatic aortic stenosis Joint session European Society of Cardiology / French Society of Cardiology 14th Journées Européennes de la Société Française de Cardiologie January 21 – January 24, 2004, Paris, France 6 Role of Dobutamine testing in the decision making for surgery in patients with aortic stenosis Joint session European Society of Cardiology / Portuguese Society of Cardiology 25th Congress of the Portuguese Society of Cardiology March 29, 2004, Vilamoura, Portugal 7 New indications for aortic valve surgery based on echocardiographic results 12th Alpe Adria Cardiology Meeting April 29 – May 1, 2004, Cividale del Friuli, Italy 8 Management of the asymptomatic patient with valve disease: from guidelines to practice: Aortic stenosis Main session European Society of Cardiology Congress 2004 August 28 – September 1, 2004, Munich, Germany 9 The burden of aortic stenosis: When is sudden death a real threat in aortic stenosis? European Society of Cardiology Congress 2004 August 28 – September 1, 2004, Munich, Germany 10 Case Presentation: 48 year old male, Systolic murmur Cardiology 2004 – Vienna & Mayo September 12 - September 14, 2004, Vienna, Austria 11 Management von Patienten mit Aortenstenose Fortbildung, Krankenhaus Tulln September 21, 2004, Tulln, Austria 12 Progression of disease and implications for monitoring: Aortic stenosis – A preventable disease? Main session Euroecho 8 December 1 – December 4, 2004, Athens, Greece 13 Update Aortenstenosen Fortbilung, Universitätsklinik für Notfallmedizin April 5, 2005, Vienna, Austria 14 Update Aortenstenose Fortbilung, 1. Med. SMZ-Ost April 25, 2005, Vienna, Austria 15 Transcatheter closure of atrial septal defects in patients of advanced age 16th International Meeting of the French Society of Echocardiography June 8 - June 10, 2005, Paris, France 16 Natural History of Aortic stenosis and echocardiographic predictors of outcome 16th International Meeting of the French Society of Echocardiography June 8 - June 10, 2005, Paris, France 17 Stressechokardiographie bei Vitien 2. Leipziger Echokardiographie-Symposium June 2005, Leipzig, Germany 18 Dobutamine Echocardiography in Valvular Heart Disease ETP Course on Cardiovascular Therapy organized by the European Society of Cardiology October 7 – October 8, 2005, Kiev, Ukraine 19 The Natural History of Aortic Stenosis – is There a Role for Statins ETP Course on Cardiovascular Therapy organized by the European Society of Cardiology October 7 – October 8, 2005, Kiev, Ukraine 20 The Patient With a High Transprosthetic Gradient ETP Course on Cardiovascular Therapy organized by the European Society of Cardiology October 7 – October 8, 2005, Kiev, Ukraine 21 Aortenklappenstenose Echokardiographie Kongress Köln November 3 – November 5, 2005, Cologne, Germany 22 From Aortic Sclerosis to Aortic Stenosis – Teaching Course Echocardiography Euroecho 9 December 3 – December 5, 2005, Florence, Italy 23 Are Practice Guidelines in Line with Recommendations with Respect to Valve Disease: Aortic Valve Diseases 16th Journées Européennes de la Société Française de Cardiologie January 18 – January 21, 2006, Paris, France 24 Patient mit asymptomatischer Aortenstenose Patient nach Klappenersatz Modernes Case-Management in der Kardiologie - interaktive Fallpräsentationen February 25, 2006, Grafenegg, Austria 25 What You Need to Know About Degenerative Mitral Regurgitation – Timing of Intervention: The Viewpoint From Vienna Symposium - American College of Cardiology 55th Annual Scientific Session March 11 – March 14, 2006, Atlanta, United States of America 26 Asymptomatic Aortic Stenosis – Degree of Calcium, Rate of Change in Peak Velocity and Role of Exercise Hemodynamics Symposium E3 Essential Echocardiography with Experts – American Society of Echocardiography March 11 2006, Atlanta, United States of America 27 Asymptomatic Aortic Stenosis Should be Treated – Pro Debator Symposium Heart to Heart Series – First Forum March 29 – March 31, 2006, Sevilla, Spain 28 Timing and Indications for Surgery in Asymptomatic Aortic Stenosis Edwards Heart to Heart Series – Module 2 April 6, 2006, Paris, France 29 Aortenklappenerkrankungen 2006 – Diagnose und Therapiemöglichkeiten: Aortenisthmusstenose State of the Art Symposium May 6, 2006, Grafenegg, Austria 30 Aortenklappenerkrankungen 2006 – Diagnose und Therapiemöglichkeiten: Aortenstenose State of the Art Symposium May 6, 2006, Grafenegg, Austria 31 Aortenstenose konservative Behandlungskonzepte: Statine, Ezetimibe oder beide Essen-Mayo-Symposium May 19 - May 20, 2006, Essen, Germany 32 Aortic Stenosis Update: From Basics to Prognosis Hadassah University Hospital May 30, 2006, Jerusalem, Israel 33 Highlights 2005: Klappenerkrankungen Österreichische Kardiologische Gesellschaft June 7 - June 10, 2006, Salzburg, Austria 34 Chairmens Summary: Featured Research Session – Rheumatic Fever / Heart Disease: Still a Challenge? European Society of Cardiology Congress/World Congress of Cardiology 2006 September 2 – September 6, 2006, Barcelona, Spain 35 Valvular Heart Disease: Asymptomatic Moderate and Severe Aortic Stenosis: ESC Guidelines, ACC/AHA Guidelines. Does MSCT play a role? Cardiology 2006 – Vienna & Mayo September 14 - September 16, 2006, Vienna, Austria 36 Aortic Stenosis: Pitfalls in Quantitative Assessment, Risk Stratification in Asymptomatic Severe AS; the Difficult Patient With Impaired LV Function and Low Gradient European Association of Echocardiography – Teaching Course: Transthoracic Echocardiography – Diagnostic Methods and Clinical Cases September 21 – September 23, 2006, Vienna, Austria 37 Asymptomatic Aortic Stenosis: Risk Stratification with Echocardiography and BNP Journées Echo-Doppler Cardio-Vasculaire September 27 – September 29, 2006, Bordeaux, France 38 Asymptomatic Mitral Regurgitation: Risk Stratification Journées Echo-Doppler Cardio-Vasculaire September 27 – September 29, 2006, Bordeaux, France 39 Operationsindikationen bei der Mitralinsuffizienz Fortbildung Herzchirurgie, Medical University of Vienna October 18, 2006, Vienna, Austria 40 Diagnostik bei Herzklappenfehlern: Aortenklappenstenose Echokardiographie Kongress Köln November 2 – November 4, 2006, Cologne, Germany 41 Neue Richtlinien und Aspekte für die Behandlung von Herzfehlern Symposium Schloss Wilhelminenberg December 2, 2006, Vienna, Austria 42 Aortic Stenosis – What and How to Measure? Euroecho 10 December 6 – December 9, 2006, Prague, Czech Republic 43 When Should we Operate on Asymptomatic Dystrophic Mitral Regurgitation? It is Possible to Wait 17th Journées Européennes de la Société Française de Cardiologie January 17 – January 20, 2007, Paris, France 44 Timing and Indications of Surgery in Degenerative Mitral Regurgitation: Debate: Watchful Waiting Master of Valve Repair Programme March 19, 2007, Harefield, United Kingdom 45 Challenges and Controversies in Valvular Heart Disease: Mitral Valve Surgery in the Asymptomatic Patient: Can it Be Justified? Symposium - American College of Cardiology 56th Annual Scientific Session March 26, 2007, New Orleans, United States of America 46 Risk Stratification and Timing of Surgery in Asymptomatic Aortic Stenosis The Center of Heart Valve Disease Meeting Bluhm Cardiovascular Institute - Northwestern University March 29, 2007, Chicago, United States of America 47 Aortenklappeninsuffizienz: wann operieren? Frühjahrstagung der Deutschen Gesellschaft für Kardiologie April 13, 2007, Mannheim, Germany 48 Aortic Regurgitation and the aortic root: Management Issues 5th Vienna Interdisciplinary Symposium on Aortic Repair (VISAR) April 19, 2007, Vienna, Austria 49 Operationsindikation bei Aortenstenose und Insuffizienz - Update 2007 im Lichte der neuen amerikanischen und europäischen Guidelines DACH meeting May 5, 2007, Vienna, Austria 50 Aortic Sclerosis, Aortic Stenosis and Lipid Lowering Therapy Cardiology and Vascular Medicie – Update and Perspective May 8, 2007, Rotterdam, Netherlands 51 Behandlung der Asymptomatischen AS: Kann eine Therapie mit Statinen oder anderen Medikamenten schon empfohlen werden? Wann kann man eine Operation rechtfertigen? Österreichische Kardiologische Gesellschaft May 31, 2007, Salzburg, Austria 52 Rôle de la quantification des valvulopathies dans la prise en charge des patients: jusqu’où? Rétrécissement aortique 17th International Meeting of the French Society of Echocardiography June 6 - June 8, 2007, Paris, France 53 Clinical standards for mitral valve repair: The „watchful waiting“approach to severe mitral regurgitation Manchester Mitral Valve Meeting 2007 June 20, 2007, Manchester, United Kingdom 54 Gradientenmessungen an Herzklappenprothesen: Wann ist eine Prothese zu klein? 6. Leipziger Echokardiographie-Symposium June 22- June 23 2007, Leipzig, Germany 55 Die konventionelle Quantifizierung des Schweregrades der Mitralstenose Echokardiographische Grundlagen 6. Leipziger Echokardiographie-Symposium June 22- June 23 2007, Leipzig, Germany 56 The valve patient and pregnancy: When should valve disease be corrected before pregnancy? European Society of Cardiology Congress 2007 September 2, 2007, Vienna, Austria 57 Mitral regurgitation - current approach: The asymptomatic patient European Society of Cardiology Congress 2007 September 3, 2007, Vienna, Austria 58 Managemt of severe mitral regurgitation Grand rounds, Rudolfstiftung hospital September 12, 2007, Vienna, Austria 59 Debate: Asymptomatic Severe Mitral Regurgitation. Watchful Waiting vs. Early Referral European Association of Cardiothoracic Surgery Meeting September 18, 2007, Geneva, Switzerland 60 Management of Asymptomatic Aortic Stenosis Echo-Cardio Symposium Benelux and Nordic Countries September 28, 2007, Brussels, Belgium 61 Clinical management of organic mitral regurgitation Third Joint Symposium of the Research Group in Valve Diseases and the Canada Research Chair in Valvular Heart Diseases October 10, 2007, Montreal, Canada 62 Clinical management of asymptomatic patients with severe aortic stenosis Third Joint Symposium of the Research Group in Valve Diseases and the Canada Research Chair in Valvular Heart Diseases October 11, 2007, Montreal, Canada 63 Timing and Indications for Surgery in Aortic stenosis and Regurgitation an Update Considering the new ESC and ACC/AHA Guidelines Ukrainian Association of Internal Medicine Training Course October 18-20, 2007, Kiev, Ukraine 64 Management of Asymptomatic Mitral Regurgitation Ukrainian Association of Internal Medicine Training Course October 18-20, 2007, Kiev, Ukraine 65 Asymptomatic Mitral Regurgitation Echokardiographie Kongress Köln November 8, 2007, Cologne, Germany 66 Prognostic value of echocardiography in valvular heart disease: aortic stenosis Euroecho 11 December 5 – December 8, 2007, Lisbon, Portugal 67 What approach concerning moderate calcific aortic stenosis 18th Journées Européennes de la Société Française de Cardiologie January 16 – January 19, 2008, Paris, France 68 Valve diseases: the crucial role of echocardiographic quantification for surgical indications - in aortic stenosis 18th Journées Européennes de la Société Française de Cardiologie January 16 – January 19, 2008, Paris, France 69 What should be used to supplement the ultrasonographic assessment of valve disease? Biomarkers? 18th Journées Européennes de la Société Française de Cardiologie January 16 – January 19, 2008, Paris, France 70 New Insights in the Pathophysiology of Aortic Stenosis Edwards Heart to Heart Series – Module 9 February 7, 2008, Paris, France 71 Debate: Severe Mitral Regurgitation in Asymptomatic Patients. Early Referral or Watchful Waiting? Watchful Waiting? Master of Valve Repair Programme February 18, 2008, Leiden, The Netherlands 72 Asymptomatic Valvular Heart Disease: There’s No Rush: Follow Carefully ACC.ClinCard 2008 - American College of Cardiology 57th Annual Scientific Session March 30, 2008, Chicago, United States of America 73 Emerging Concepts in the Pathogenesis of Aortic Valve Disease: Biomarkers and Progression Symposium - American College of Cardiology 57th Annual Scientific Session March 31, 2008, Chicago, United States of America 74 The Natural History of Aortic Stenosis Edwards Heart to Heart Series April 11, 2008, Rome, Italy 75 Aortic Sclerosis, Aortic Stenosis and Lipid Lowering Therapy Sesión Clínica General, Hospital General Vall d’Hebron June 6, 2008, Barcelona, Spain 76 Noncardiac Surgery in Asymptomatic Aortic Stenosis European Society of Cardiology Congress 2008 September 1, 2008, Munich, Germany 77 Timing of Surgery in Asymptomatic Aortic Regurgitation Edwards Heart to Heart Series – Module 14 October 2, 2008, Paris, France 78 Aortenstenose: von der Pathogenese zur Risikostratifizierung Experten Meeting „State of the Art – Aortenstenose“ October 3, 2008, Vienna, Austria 79 Percutaneous Aortic Valve Implantation British Society of Echocardiography October 4, 2008, Leeds, United Kingdom 80 Aortic Regurgitation – Timing of Surgery International Training Course October 16-18, 2008, Kiev, Ukraine 81 Aortic Stenosis – From Pathogenesis to Risk Stratification International Training Course October 16-18, 2008, Kiev, Ukraine 82 Case Presentation - Aortic Stenosis – Calcification, Jet Velocity and Progression International Training Course October 16-18, 2008, Kiev, Ukraine 83 Management of Asymptomatic Severe Aortic Stenosis: Listen to the Patient and Look at the Valve American Heart Association Scientific Sessions 2008 November 9, 2008, New Orleans, United States of America 84 The Dilemma of Timing for Surgery in Mitral Regurgitation: The „watchful waiting“ approach Mitrale Meeting 2008 November 20, 2008, Milan, Italy 85 New Frontiers in Mitral Regurgitation: Tools Helping to Predict Outcome Symposium of the Belgian Working Group of Non-invasive Cardiology 2008 November 22, 2008, Liège, Belgium 86 Aortic root evaluation: The problem of aortic valvular disease due to ascending aortic disease Euroecho 12 December 5 – December 8, 2008, Lyon, France 87 Prognostic value of calcium in the aortic valve Euroecho 12 December 5 – December 8, 2008, Lyon, France 88 Asymptomatic Severe Aortic Stenosis: Calcification, Progression and Exercise Testing ESC - ETP Course Heart House February 19-21, 2009, Sophia Antipolis, France 89 Asymptomatic Severe Mitral Regurgitation: Watchful Waiting or Surgery? ESC - ETP Course Heart House February 19-21, 2009, Sophia Antipolis, France 90 Low Gradient Aortic Stenosis and Heart Failure ESC - ETP Course Heart House February 19-21, 2009, Sophia Antipolis, France 91 The Patient with a High Transprosthetic Gradient ESC - ETP Course Heart House February 19-21, 2009, Sophia Antipolis, France 92 Asymptomatische wirksame Aortenstenose: Natürlicher Verlauf und Zeitpunkt der Operation beziehungsweise Intervention Kardiologie Innsbruck March 6-7, 2009, Innsbruck, Austria 93 New Insights in the Pathophysiology of Aortic Stenosis and Review of Statin Trials Edwards Heart to Heart Series March 12, 2009, Paris, France 94 Early Elective Surgery in Severe Asymptomatic Aortic Stenosis: When I do it, when I don’t Edwards Heart to Heart Series March 12, 2009, Paris, France 95 Mitralklappenvitien: Indikationen zur Klappenoperation Fortbildung Herzchirurgie, Medical University of Vienna March 25, 2009, Vienna, Austria 96 Aortic root diseases: Treatment of concomitant aortic valve disease – the role of TTE 6th Vienna Interdisciplinary Symposium on Aortic Repair (VISAR) April 22, 2009, Vienna, Austria 97 When to operate on asymptomatic aortic stenosis? „Indications opératoires en cas de rétrécissement aortique asymptomatique“ 18th International Meeting of the French Society of Echocardiography May 27-29, 2009, Paris, France 98 Decisional Value of echocardiography in the treatment of valvular heart diseases: Aortic Stenosis „Valeur décisionelle de l’échocardiographie dans la prise en charge thérapeutique des valvulopathies: rétrécissement aortique“ 18th International Meeting of the French Society of Echocardiography May 27-29, 2009, Paris, France 99 Highlight Session: Valvular Heart Disease European Society of Cardiology Congress 2009 September 2, 2009, Barcelona, Spain 100 Stratifying risk in the Asymptomatic Patient with Severe Valvular Heart Disease: Aortic Stenosis European Society of Cardiology Congress 2009 September 1, 2009, Barcelona, Spain 101 Difficult Decisions in Aortic Stenosis: Risk Stratification and Timing of Surgery European Society of Cardiology Congress 2009 September 1, 2009, Barcelona, Spain 102 Bicuspid Aortic Valve Disease September 18-19, 2009, St Malo, France 103 Decision Making and Optimal Timing of Mitral Valve Treatment in Elderly Patients European Association of Cardiothoracic Surgery Meeting October 17-21, 2009, Vienna, Austria 103 Management of the Patient with Asymptomatic Mitral Valve Disease: Wachful Waiting vs Surgery Before it is Too Late American Heart Association Scientific Sessions 2009 November 15, 2009, Orlando, United States of America Invited Chairs at International Scientific Meetings 1 Chairman: Contemporary management of aortic valve disease (Co-Chairman Dan Gilon, Jerusalem IL) European Society of Cardiology Congress 2003 August 30 – September 3, 2003, Vienna, Austria 2 Chairman: Moderated Poster Session 16th International Meeting of the French Society of Echocardiography June 8 - June 10, 2005, Paris, France 3 Chairman: Stress-echokardiographie bei Vitien (Co-Chairman Wolfgang Fehske, Köln DE) 2. Leipziger Echokardiographie-Symposium Juni 2005, Leipzig, Germany 4 Chairman: Aortic Regurgitation and the Aortic Root (Co-Chairman Eric Butchart, Cardiff, GB) European Society of Cardiology Congress 2005 September 3 – September 7, 2005, Stockholm, Sweden 5 Chairman: Predicting Outcome in Valve Disease (Co-Chairman Catherine Otto, Seattle US) European Society of Cardiology Congress 2005 September 3 – September 7, 2005, Stockholm, Sweden 6 Chairman: Pharmacotherapy of Coronary Artery Disease – Controversial Issues and Feedback (Co-Chairman G Dzak, Dnipetrovsk UA and Viktor Tashchuck, Chernivci UA) ETP Course on Cardiovascular Therapy organized by the European Society of Cardiology October 7 – October 8, 2005, Kiev, Ukraine 7 Chairman: Arterial Hypertension – some Pharmacotherapeutic Aspects (Co-Chairman Boris Mankovskyi, Kiev UA and Maryna Dolzhenko, Kiev UA) ETP Course on Cardiovascular Therapy organized by the European Society of Cardiology October 7 – October 8, 2005, Kiev, Ukraine 8 Chairman: Special Cardiology in Clinical Situations – Optimization of Treatment Approaches (Co-Chairman Yu Sirenko, Kiev UA and Marina Sharayeva, Kiev UA) ETP Course on Cardiovascular Therapy organized by the European Society of Cardiology October 7 – October 8, 2005, Kiev, Ukraine 9 Chairman: Are Practice Guidelines in Line with Recommendations with Respect to Valve Disease? (Co-Chairman Christophe Tribouilloy, Amiens, FR) 16th Journées Européennes de la Société Française de Cardiologie January 18 – January 21, 2006, Paris, France 10 Chairman: Aortenklappenerkrankungen 2006 – Diagnose und Therapiemöglichkeiten State of the Art Symposium (Co-Chairman Herbert Frank, Tulln, AT) May 6, 2006, Grafenegg, Austria 11 Chairman: Towards less Invasive Treatment of Valve Disease (Co-Chairman Manuel Antunes, Coimbra PT) European Society of Cardiology Congress 2006 September 2 – September 6, 2006, Barcelona, Spain 12 Chairman: Featured Research Session – Rheumatic Fever / Heart Disease: Still a Challenge? (Co-Chairman A Achutti, Porto Alegre BR) European Society of Cardiology Congress/World Congress of Cardiology 2006 September 2 – September 6, 2006, Barcelona, Spain 13 Chairman: Moderated Poster Session: Valvular Heart Disease and Pulmonary Hypertension Österreichische Kardiologische Gesellschaft May 31, 2007, Salzburg, Austria 14 Rôle de la quantification des valvulopathies dans la prise en charge des patients: jusqu’où? (Co-Chairman: Eric Abergel, FR) 17th International Meeting of the French Society of Echocardiography June 6 - June 8, 2007, Paris, France 15 Chairman: Abstract Session: Aortic Stenosis – New directions (Co-Chairman: Janina Stepinska, Warsaw PL) European Society of Cardiology Congress 2007 September 2, 2007, Vienna, Austria 16 Chairman: Pharmacotherapy of Coronary Artery Disease – Controversial Issues and Feedback (Co-Chairman G Dzak, Dnipetrovsk UA and Viktor Tashchuck, Chernivci UA) ETP Course on Cardiovascular Therapy organized by the European Society of Cardiology October 19 – October 20, 2007, Kiev, Ukraine 17 Chairman: Arterial Hypertension – some Pharmacotherapeutic Aspects (Co-Chairman Boris Mankovskyi, Kiev UA and Maryna Dolzhenko, Kiev UA) ETP Course on Cardiovascular Therapy organized by the European Society of Cardiology October 19 – October 20, 2007, Kiev, Ukraine 18 Chairman: Kongenitale Vitien im Erwachsenenalter (Co-Chairman Konrad Brockmeier, Cologne DE) Echokardiographie Kongress Köln November 8, 2007, Cologne, Germany 19 Chairman: New applications of imaging techniques in aortic stenosis (Co-Chairman: Gerald Maurer, Vienna AT) Euroecho 11 December 5 – December 8, 2007, Lisbon, Portugal 20 Panelist: Asymptomatic Valvular Heart Disease ACC.ClinCard 2008 - American College of Cardiology 57th Annual Scientific Session March 30, 2008, Chicago, United States of America 21 Chairman: Bicuspid Aortic Valve Disease: An Old Disease With a New Name? (Co-Chairman: Janina Stepinska, Warsaw PL) European Society of Cardiology Congress 2008 August 8, 2008, Munich, Germany 22 Chairman: Surgical Mortality in Low Gradient Aortic Stenosis Symposium of the Belgian Working Group of Non-invasive Cardiology 2008 November 22, 2008, Liège, Belgium