(DRAFT SCHEDULE) INFECTIOUS DISEASES OF ADULTS – 2008 April 13 – April 18, 2008 PROGRAM DIRECTORS: Stephen B. Calderwood, M.D., Nesli Basgoz, M.D. and Jay A. Fishman, M.D. Sunday - April 13th 7:00 P.M. - 9:00 P.M. PRE-REGISTRATION Monday – April 14th 7:00 - 8:00 A.M. REGISTRATION (Continental Breakfast served) 8:00 - 8:10 Introduction - Dr. Stephen B. Calderwood SESSION 1 MODERATOR: Dr. Stephen B. Calderwood 8:10 - 9:05 Review of Major Antimicrobial Classes and Empiric Therapy S. B. Calderwood 9:10 - 10:05 Newer Antimicrobial Agents D.C.Hooper 10:10 - 10:30 Coffee Break 10:30 - 11:25 Antimicrobial Resistance and Infection Control D.C. Hooper 11:30 - 12:25 Endocarditis A. W. Karchmer 12:30 - 1:45 Lunch Break SESSION 2 MODERATOR: Dr. Jay A. Fishman 1:45 – 2:15 Approach to Sepsis T. Thompson 2:20 – 3:00 Urinary Tract Infections TBA 3:05 - 3:25 Coffee Break 3:25 - 4:15 Community-Acquired and Nosocomial Pneumonia J.A. Fishman 4:20 - 5:05 Skin and Soft Tissue Infections TBA Tuesday - April 15th 8:00 - 9:00 A.M. Clinical Cases: Images in Infectious Diseases (Interactive) R. Gandhi (Continental Breakfast served) SESSION 3 MODERATOR: Dr. Stephen B. Calderwood 9:00 - 10:00 Meningitis V.J. Quagliarello 10:05 - 10:25 Coffee Break 10:25 – 11:20 Osteomyelitis and Prosthetic Joint Infections A. W. Karchmer 11:25 – 12:25 Hepatitis J. Dienstag 12:30 - 1:45 Lunch Break SESSION 4 MODERATOR: Dr. Nesli Basgoz 1:45 - 2:45 Sexually Transmitted Diseases TBA 2:50 - 3:50 Tuberculosis and Pulmonary Nontuberculous Mycobacterial Infection N. Basgoz 3:55- 4:15 Coffee Break 4:15 - 5:15 Common ID Curbside Consults (Interactive) P.E. Sax 5:15 - 7:15 Reception Course Directors Wednesday - April 16th SESSION 5 MODERATOR: Dr. Bruce D. Walker 8:00 - 8:50 HIV Pathogenesis and Vaccine Development B. D. Walker 8:55 - 9:25 Acute HIV Syndromes E. S. Rosenberg 9:30 - 9:50 Coffee Break 9:50 - 10:50 Treatment of HIV Infection D. Kuritzkes 10:55 - 11:55 Opportunistic Infections in AIDS H. Heller 12:00 - 1:15 Lunch Break SESSION 6 1:15 - 2:15 Case Records of the Massachusetts General Hospital (For Publication in the New England Journal of Medicine) TBA MODERATOR: Dr. Nesli Basgoz 2:15 - 3:00 New and Emerging Viruses and Prions M. S. Hirsch 3:05 - 3:25 Coffee Break 3:25 - 4:10 Non-HIV Antiviral Chemotherapy M. S. Hirsch 4:15 - 5:10 Infections of the Eyes, Ears and Sinuses M.L. Durand Thursday - April 17th 8:00 –8:45 A.M. Discussion by Faculty of Clinical Cases provided by Course Participants (Continental Breakfast served) SESSION 7 Moderator: Dr. Jay A. Fishman 8:45 - 9:45 Infections in the Compromised Host: Transplantation & Neutropenia J. A. Fishman 9:50 - 10:35 Endemic Fungal Infections T.F. Patterson 10:40 - 11:00 Coffee Break 11:00 - 11:50 Anti-Fungal Therapy 11:55 - 1:10 Lunch Break T.F. Patterson SESSION 8 MODERATOR: Dr. Stephen B. Calderwood 1:10 – 1:55 Molecular Diagnostics A. Caliendo 2:00 - 3:00 Bacterial Gastroenteritis and C. difficile S.B. Calderwood 3:05 - 3:25 Coffee Break 3:25 - 4:25 Tropical Medicine and Parasitology E.T. Ryan 4:30 – 5:00 Travel Medicine and Immunizations E.T. Ryan Friday - April 18th SESSION 9 MODERATOR: Dr. Stephen B. Calderwood 8:00 - 8:55 Bites, Scratches, and Rabies N. Basgoz 9:00 - 10:00 Zoonotic Infections J. Koehler 10:05 - 10:25 Coffee Break 10:25 - 11:20 Tick-borne Illnesses H. Heller 11:25 - 11:55 Bioterrorism S.B. Calderwood 12:00 Adjourn COURSE OBJECTIVES This course provides an in-depth and up-to-date synthesis of major advances in the field of clinical Infectious Diseases. Participants will: Improve clinical skills in Infectious Diseases Learn the latest strategies for the prevention, recognition, diagnosis, and treatment of important syndromes in Infectious Diseases Be able to establish a differential diagnosis and initiate an appropriate diagnostic evaluation for the major infectious disease-related problems in clinical practice Understand relevant areas of basic science to enable both the comprehension and the application of future discoveries to patient care Have personal interaction with leaders in Infectious Disease from a distinguished faculty WHO SHOULD ATTEND Healthcare professionals who require a critical and comprehensive update of infectious diseases to enhance their professional capabilities: Infectious Disease Specialists Fellows Preparing for ID Certification Specialists with an Interest in ID Primary Care Physicians Critical Care Specialists Family Practitioners Pharmaceutical Specialists COURSE DESCRIPTION The 33rd annual Infectious Diseases of Adults postgraduate course is designed to review state-of-the-art information in the diagnosis and management of important infectious disease problems in current medical practice. This highly rated course focuses on major clinical syndromes and management controversies in infectious disease. Topics with major impact on clinical practice are emphasized including: antibiotic resistance, sexually transmitted diseases, endocarditis, vaccination, hospital epidemiology, infections in pregnancy, zoonotic infections, parasitology, new viral pathogens, molecular diagnostics, newer guidelines for the prevention of tuberculosis and bioterrorism. The care of the patient with HIV/AIDS is discussed in detail: the biology of the infection, epidemiology, antiviral therapies, ambulatory management, and the prevention and treatment of opportunistic infections. The management of infections in the growing population of immunocompromised hosts will be reviewed. Emphasis is given to recent developments in the management and prevention of infections, including the newer antibiotics, new vaccines, antiviral and antiparasitic agents, new diagnostic techniques and recommendations for prophylaxis in travelers. This course focuses on advances in infectious diseases and their application to direct patient care. Didactic lectures and case-based presentations are both featured. An extensive, well-referenced syllabus supplements the presentations. Ample opportunity for interaction with the expert faculty is provided, including interactive clinical sessions and formal and informal discussions of cases provided by the faculty and by course participants. SPRINGTIME IN BOSTON The course is presented at a locale that allows participants to enjoy the many attractions of springtime in Boston. Attendees will have access to nearby restaurants, famous shops of Newberry street and the Copley Place mall, and paths along the Charles River for walking, jogging, or bicycling. Public transportation to all of Boston and Cambridge via the “T” is adjacent to the hotel. Harvard Square, The Freedom Trail, Faneuil Hall, Fenway Park, the Museum of Fine Arts, the Science Museum and the Children’s Museum are readily accessible. Special trips may be arranged with the assistance of the concierge of the Fairmont Hotel, where blocks of rooms have been reserved at a special reduced conference rate. All sessions, the course syllabus, continental breakfasts, morning and afternoon refreshments, and Tuesday evening reception are included in the registration fee. ACCREDITATION Harvard Medical School is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to sponsor continuing medical education for physicians. Harvard Medical School designates this educational activity for a maximum of 33 hours in category 1 credit towards the AMA Physician’s Recognition Award. Each physician should claim only those hours of credit that he/she actually spent in the educational activity. This program has been reviewed and is acceptable for 33 Prescribed Hours by the American Academy of Family Physicians. This program is designed to meet the criteria for 5 hours of Category 1 Risk Management credit in Massachusetts. REGISTRATION INFORMATION Tuition Fee - $925 (U.S.). Reduced Fee for Residents, Fellows and Allied health Professionals (with a letter of verification from Department Chairman) - $525 (U.S.). Please make check payable to Harvard Medical School (credit cards not accepted) and mail with application form to Harvard MED-CME, P.O. Box 825, Boston, MA 02117-0825. All foreign payments must be made by a draft on a United States Bank. Inquiries should be directed to the above address or made by phone: (617) 432-1525. Monday-Friday, 10 a.m. to 4 p.m. (Eastern Time), or by e-mail: hms-cme@warren.med.harvard.edu ON-LINE INFORMATION To view course information on-line, visit our home page: http://www.med.havard.edu/conted/ TUITION REFUND POLICY A handling fee of $50 is deducted for cancellation. Refund requests must be received by mail one week prior to the course. No refunds will be made thereafter. COURSE LOCATION All sessions will be held at the Fairmont Copley Plaza Hotel, 138 St. James Avenue Boston, MA 02116 (Telephone: 617-267-5300), Copley Station on Green Line of the MBTA Subway. ACCOMMODATIONS Hotel rooms are limited. Participants are urged to make their reservations early. A block of rooms has been reserved at a discounted rate at the Fairmont Copley Hotel until March 23,2008. Please specify that you are enrolled in this course to receive the reduced room rate. A map of Boston/Cambridge listing local hotels will be sent with your confirmation of enrollment. For bed and breakfast information, call (617) 332-4199. TRAVEL For information about reduced airfare, call the Harvard Travel Center at 1-800-HMS-TRVL (1-800-467-8785). Outside of the U.S., Canada, and Virgin Islands please call: 1-617496-8000, option 7. Program Directors Stephen B. Calderwood, M.D, Nesli Basgoz, M.D. and Jay A. Fishman, M.D. HARVARD MEDICAL SCHOOL FACULTY Jules L. Dienstag Marlene L. Durand Donna Felsenstein Rajesh Gandhi Howard Heller Martin S. Hirsch David C. Hooper Adolf W. Karchmer Daniel Kuritzkes Eric Rosenberg Eric J. Rubin Edward T. Ryan Paul E. Sax B. Taylor Thompson Bruce D. Walker Sigal Yawetz GUEST FACULTY Angela Caliendo, M.D., Ph.D. Associate Professor of Medicine Vice Chair, Department of Pathology and Laboratory Medicine Emory University Clinical Laboratories Jane Koehler, M.D. Professor of Medicine and Attending Physician Division of Infectious Disease University of California at San Francisco Thomas Patterson, M.D. Director, San Antonio Center for Medical Mycology Professor of Medicine,Division of Infectious Diseases The University of Texas Health Science Center at San Antonio Vincent J. Quagliarello, M.D. Professor of Medicine, Clinical Director and Acting Chief Infectious Diseases Section, Yale University School of Medicine