Respiratory Tract Research, initiated between 1 January 2001 and 31 December
2002
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Eastern
London
National
Northern & Yorkshire
North-West Scotland
South-East
South-West
Trent
West Midlands
Wales
Eastern Region
TITLE: A study to compare oral moxifloxacin to standard intra venous and oral
therapy for the treatment of patients with Community Acquired Pneumonia.
CONTACT: Dr Robert Winter UNIT: Cambridge Consortium - Addenbrookes
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0544099348
TITLE: Community-acquired pneumonia mortality CONTACT: Prof David Price
UNIT: Suffolk and Norfolk Research and Development Consortium (S.A.N.D.)
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0548139425
TITLE: Evaluation of the immunogenicity and reactogenicity of a pneumococcal
vaccine in healthy adults aged 50-80 years, and subsequent antibody persistence and
response to boosting. CONTACT: Dr E Miller UNIT: Hertfordshire RM&G
Collaborative/WelHat PCT
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0633136887
TITLE: Lymphocyte subsets in respiratory syncytial virus infection in children.
CONTACT: Dr Diarmuid Rodney ODonnell UNIT: Cambridge Consortium Addenbrookes
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0544116584
TITLE: Risk Factors for hospitalisation among older people with acute respiratory
disease during the winter CONTACT: Ms Rachel Jordan UNIT: West Lincolnshire
Primary Care Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0617131751
TITLE: The effect of macrolide antibiotics on the outcome of acute bronchiolitis in
infants CONTACT: Dr Andrew T Clark UNIT: Cambridge Consortium Addenbrookes
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0544103921
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London Region
TITLE: A case control study of fatigue symptoms and syndrome following infectious
mononucleosis CONTACT: Dr Peter White UNIT: East London and The City
Mental Health NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0146103032
TITLE: A prospective, placebo controlled, double-blind randomised cross over study
evaluating the effects of xylitol-containing chewing gum versus ordinary chewing
gum on recurrent purulent upper respiratory tract infections CONTACT: Dr Peter
Andrews UNIT: The Royal Free Hampstead NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0256119254
TITLE: A quantitative exploration to determine whether or not pathogenic micro
organisms are present on respiratory equipment used in pre-hospital care
CONTACT: Mr Liam Whittaker UNIT: London Ambulance Service NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0352123789
TITLE: A Randomised Comparative Study of Two Different Schedules for the
Administration of anti-Pneumococcal Vaccine in Children receiving Haemopoietic
Progenitor Transplants. CONTACT: Dr Miguel Ortin UNIT: The Royal Marsden
NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0258123552
TITLE: A randomised comparative trial of liposomal amphotericin B versus
fluconazole in the treatment of systemic Candida infections in non-neutropenic
patients CONTACT: Dr Stephen Brett UNIT: Hammersmith Hospital NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0016103233
TITLE: A study to determine the immunogenicity of influenza vaccine in children
with solid tumours CONTACT: Dr JC Chisholm UNIT: Great Ormond Street
Hospital for Children NHS Trust / Institute of Child Health.
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0012101638
TITLE: A Study to Determine the Immunogenicity of Influenza Vaccine in Children
with Solid Tumours. CONTACT: Dr Mary Taj UNIT: The Royal Marsden NHS
Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0258107438
TITLE: Allelic variation in the secretory-component binding domain of
Pneumococcal cbpA CONTACT: Dr Indran Balakrishnan UNIT: The Royal Free
Hampstead NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0256126957
TITLE: An evaluation of the performance of near patient tests for Influenza and their
application for clinical decision in Primary Care CONTACT: Professor Anne
Johnson UNIT: North Central London Research Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0530105334
TITLE: An investigation into mechanisms regualting inflammatory cell influx in
Respiratory Syncytial Virus Infection. CONTACT: Dr Jon Friedland UNIT:
Hammersmith Hospital NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0016137155
TITLE: An Open Label Non-comparative Study of Safety and Efficacy of
Intravenous Anidulafungin Plus AmBisome as a Treatment for Invasive Aspergillosis.
CONTACT: Professor Raymond Powles R UNIT: The Royal Marsden NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0258113045
TITLE: Analysis of pneumococcal antibody titres and meningococcal and antibody
avidity CONTACT: Dr D Goldblatt UNIT: Great Ormond Street Hospital for
Children NHS Trust / Institute of Child Health.
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0012101623
TITLE: Analysis of virulence factors involved in the pathogenesis of bacterial
infections in people with cystic fibrosis. CONTACT: Prof Mike Curtis UNIT: Barts
and The London NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0205114481
TITLE: Antibody response and immunological memory to a conjugate
pneumococcal vaccine in premature infants CONTACT: Dr Paul Heath UNIT: St
Georges Healthcare NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0236111667
TITLE: C!q- dependant innate immunity to streptococcus pneumonae CONTACT:
Dr J Brown UNIT: Hammersmith Hospital NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0016118953
TITLE: Can influenza immunisation of staff at nursing/residential homes prevent
sickness absence and protect residents from influenza? - A pilot study. CONTACT:
Dr Andrew Hayward UNIT: North Central London Research Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0530108377
TITLE: Characterisation of aspergillus fungatus antigen expression in relation to
clinical backgrounds CONTACT: Dr Elaine Bignell UNIT: Hammersmith Hospital
NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0016111500
TITLE: Clinical burden and pharmacoeconomic analysis of Influenza in Infants and
young children. CONTACT: Professor Robert Booy UNIT: Barts and The London
NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0205119411
TITLE: Community acquired pneumonia - what are the causes? CONTACT:
Professor Robert Booy UNIT: Barts and The London NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0205104613
TITLE: Comparison of oral moxifloxacin versus standard IV and oral comparator
regimen (B-lactam and macrolide) in the treatment of community-acquired
pneumonia. CONTACT: Dr Onn Min Kon UNIT: St Marys NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0241092420
TITLE: Contribution of the type III secretion system to the pathogenesis of
P.aeruginosa infections in model systems and cystic fibrosis patients CONTACT:
Prof Mike Curtis UNIT: Barts and The London NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0205144782
TITLE: Describing household transmission of respiratory syncitial virus (RSV)
infection in families of infants presenting to paediatric intensive care units in London.
CONTACT: Dr Natasha Crowcroft UNIT: St Marys NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0241092408
TITLE: Describing household transmission of respiratory syncytial virus infection in
families of infants presenting to paediatric intensive care units in London, United
Kingdom. CONTACT: Professor Robert Booy UNIT: Barts and The London NHS
Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0205093891
TITLE: Development of a PCR-RFLP assay to determine the susceptibility of
streptococcus pneumoniae to penicillin CONTACT: Dr K Harris UNIT: Great
Ormond Street Hospital for Children NHS Trust / Institute of Child Health.
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0012101628
TITLE: Enhanced surveillance for influenza in nursing and residential homes in
Camden and Islington using clinical surveillance and near-patient tests CONTACT:
Dr Stephen Conaty UNIT: North Central London Research Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0530108381
TITLE: Environmental Mycobacteria and childhood allergies CONTACT: Dr P
Cullinan UNIT: Royal Brompton and Harefield NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0201115798
TITLE: Establishing novel methodology to measure pneumococcal antibodies (PncEURO) CONTACT: Dr D Goldblatt UNIT: Great Ormond Street Hospital for
Children NHS Trust / Institute of Child Health.
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0012095980
TITLE: Evaluation of novel pneumococcal vaccines CONTACT: Dr D Goldblatt
UNIT: Great Ormond Street Hospital for Children NHS Trust / Institute of Child
Health.
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0012095862
TITLE: Genetic diversity of strains of pseudomonas aeroginosa from chronic airway
infections in cystic fybrosis patients and other clinical sources CONTACT: Dr
Robert Whiley UNIT: Barts and The London NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0205144678
TITLE: Immunogenicity and safety of Pneumococcal conjugate vaccine in children
with Sickle Cell Disorder CONTACT: Professor Robert Booy UNIT: Barts and The
London NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0205119412
TITLE: Improved methods of detection of chlamydia pneumoniea in cases of
pneumonia. CONTACT: Mr Paul Taylor UNIT: Royal Brompton and Harefield
NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0201112837
TITLE: Investigation of the relationship between glucose and bacteria in the airway
of patients with COPD when stable and during exacerbations CONTACT: Dr Emma
Baker UNIT: St Georges Healthcare NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0236102652
TITLE: Investigation of the role of Chlamydia pneumoniae in respiratory tract
infection in the immunocompromised patient. CONTACT: Dr Marianne Nolan
UNIT: Hammersmith Hospital NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0016131969
TITLE: Morbidity of pneumococcal meningitis in UK 1996-1999 CONTACT:
Person External UNIT: The Royal Free Hampstead NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0256114020
TITLE: Non-invasive diagnosis of ventilator-associated pneumonia using exhaled
breath condensate CONTACT: Dr Mark Griffiths UNIT: Royal Brompton and
Harefield NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0201109274
TITLE: Non-neutropenic Candida infection treatment study CONTACT: Dr Marthin
Mostert UNIT: University Hospital Lewisham NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0124101872
TITLE: Non-neutropenic candida infection treatment study. CONTACT: Dr
Stephen Brett UNIT: Hammersmith Hospital NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0016132006
TITLE: Patterns of interstitial pneumonia in an acute setting. CONTACT: Dr
Alexandra Rice UNIT: Royal Brompton and Harefield NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0201109288
TITLE: Pseudomonas aeruginosa virulence gene expression in vivo in the
Caenorhabditis elegans pathogenicity model using unstable green fluorescent protein
reporters CONTACT: Prof Mike Curtis UNIT: Barts and The London NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0205070020
TITLE: Role of host immune response in mycobacterial persistence CONTACT:
Professor Douglas Brownlie Young UNIT: St Marys NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0241103165
TITLE: Study to investigate the effect of upper respiratory tract infection on vascular
endothelial function CONTACT: Professor Juan Carlos Kaski UNIT: St Georges
Healthcare NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0236102661
TITLE: The association of seropositivity for Chlamydia pneumoniae and venous
thromboembolism - a case control study CONTACT: Dr Zelma Hall UNIT: North
Middlesex Hospital NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0157097240
TITLE: The effectiveness and cost effectiveness of immunising staff at
nursing/residential homes for the elderly protect residents against influenza
CONTACT: Dr Andrew Hayward UNIT: North Central London Research
Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0530147256
TITLE: The immunopathogenesis of Mycobacterium ulcerans infection CONTACT:
Dr Mark Wansbrough-Jones UNIT: St Georges Healthcare NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0236102607
TITLE: The role of dendritic cells in RSV infection and RSV induced reactive
airway disease. CONTACT: Dr Jurgen Schwarze UNIT: St Marys NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0241121233
TITLE: Topical amphotericin B in chronic rhinosinusitis CONTACT: Prof Valerie J
Lund UNIT: The Royal Free Hampstead NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0256146957
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National
TITLE: AN EVALUATION OF INEQUALITIES IN INFLUENZA
VACCINATION COVERAGE IN THE ELDERLY CONTACT: Dr Punam
Mangtani UNIT: Department of Health (PRP) Policy Research Program
http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0005095644
TITLE: EVALUATING THE POTENTIAL EFFECTS OF INFLUENZA
VACCINATION OF NHS STAFF ON INFECTION RATES AMONGST
PATIENTS IN HOSPITALS AND CARE HOMES (SCOPING STUDY)
CONTACT: Professor Steve Gallivan UNIT: Department of Health (PRP) Policy
Research Program
http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0005101457
TITLE: PHASE I/II STUDIES OF INFLUENZA H5N3 VACCINE CONTACT: Dr
Karl Nicholson UNIT: Department of Health (PRP) Policy Research Program
http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0005043651
TITLE: Promoting universal influenza immunisation in older people CONTACT:
Professor Karl Graham Nicholson UNIT: National Coordinating Centre for Health
Technology Assessment (NCCHTA)
http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0048091388
TITLE: RESEARCH ON VACCINATING HEALTH CARE WORKERS
AGAINST INFLUENZA CONTACT: Dr Julia Smedley UNIT: Department of
Health (PRP) Policy Research Program
http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0005125196
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Northern and Yorkshire Region
TITLE: A case control study to determine whether community-acquired pneumonia
poses a risk for the development of bronchiectasis in children CONTACT: Dr D
Spencer UNIT: Newcastle upon Tyne Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0503106386
TITLE: A retrospective audit of the clinical efficacy of the Candida and Aspergillus
antigen (Platelia) tests for diagnosis of candidosis and aspergillosis CONTACT: Dr
H R Ashbee UNIT: Leeds Teaching Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0436130306
TITLE: Antibody response in pre-term infants vaccinated at chronological age with
the accelerated UK schedule and the effect of dexamethasone on this response
(PREMIS-PREterM Immunisation Study) CONTACT: Dr Janet E Berrington UNIT:
NHS Executive Northern and Yorkshire
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0461108789
TITLE: Bacterial/Epithelial interactions in human tonsils CONTACT: Mr Gerard
Siou UNIT: Newcastle upon Tyne Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0503114972
TITLE: Causes of pneumonia in children presenting to hospital - the role of
Streptococcus pneumonia CONTACT: Dr F J Hampton UNIT: South Tees Hospitals
NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0227113240
TITLE: Comparison of Oral Moxifloxacin vs Standard IV and Oral Comparator
Regimen (ß-Lactam and Macrolide) in the Treatment of Community Acquired
Pneumonia. CONTACT: Dr R.W. Heaton UNIT: Calderdale and Huddersfield NHS
Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0083099521
TITLE: Mannose-binding lectin and surfactant proteins A and D as modifiers of
infection in cystic fibrosis CONTACT: Dr S P Conway UNIT: Leeds Teaching
Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0436130421
TITLE: Pilot study to evaluate the role of endothelin in the experimental rhinovirus
cold CONTACT: Dr Anthony Redington UNIT: NHS Executive Northern and
Yorkshire
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0461108815
TITLE: Pseudomona Showers and Patients CONTACT: Ms Beverley Reilly UNIT:
North Tees and Hartlepool NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0159121888
TITLE: Pseudomonas Acquisition, its effect on respiratory function and exercise
ability CONTACT: Mrs L Morrison UNIT: Leeds Teaching Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0436130367
TITLE: Questionnaire on the uptake of, and indicators for influenza immunisation in
children attending the Sunningdale School. CONTACT: Dr A Groves UNIT: City
Hospitals Sunderland NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0065114646
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North-West
TITLE: A M/C, M/N, Prospective, Randomised, D/B Study to compare the efficacy
and safety of Faropenem Daloxate 300mg for 10 days with Co-amoxiclav 500/125mg
for 10 days in treatment of adult patients with bacterial community-acquired
pneumonia CONTACT: Dr Christopher James Warburton UNIT: Aintree Hospitals
NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0025093077
TITLE: Antibody response and immunological memory to a conjugate
pneumococcal vaccine in premature infants CONTACT: Dr MJ Robinson UNIT:
Salford Royal Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0217110488
TITLE: Comparison of susceptibility testing methods for flucytosine in Candida sp EUCAST vs. NCCLS CONTACT: Dr DW Denning UNIT: Salford Royal Hospitals
NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0217097822
TITLE: Evaluation of a polymerase chain reaction (PCR)-based method for
identification of an epidemic Pseudomonas aeruginosa strain in cystic fibrosis
patients. CONTACT: Dr Stavroula Panagea UNIT: Royal Liverpool and Broadgreen
University Hospitals Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0207112405
TITLE: Impact of genetic risk factors and epidemiology of chronic necrotising
(fibrosing) pulmonary aspergillosis (CNPA) and aspergilloma CONTACT: Dr David
W Denning UNIT: South Manchester University Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0226118464
TITLE: Influenza vaccination in hospitalised elderly patients CONTACT: Dr Glyn
Scott UNIT: St Helens and Knowsley Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0237109526
TITLE: Pneumococcal vaccines for sickle cell disease in children and adults
(Cochrane Review) CONTACT: Ms C Riddington UNIT: Royal Liverpool
Childrens NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0206142574
TITLE: Prophylactic antibodies for preventing pneumococcal infection in people
with sickle cell disease (Cochrane Protocol) CONTACT: Ms C Riddington UNIT:
Royal Liverpool Childrens NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0206102402
TITLE: RCT to assess safety & acceptance of the 2001/2001 season intranasal
influenza vaccine vs intramuscular influenza vaccine CONTACT: Dr John Wearne
UNIT: Ellesmere Port & Neston Primary Care Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0615134681
TITLE: Respiratory syncytial virus (RSV) bronchiolitis CONTACT: Dr M G
Semple UNIT: Royal Liverpool Childrens NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0206108972
TITLE: Serum titre of antipneumococcal antibody and ant-haemophilus antibody in
patients with a history of positive cultures for pneumococcus but no evidence of
bronchiectasis CONTACT: Dr PJ Sullivan UNIT: Salford Royal Hospitals NHS
Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0217106469
TITLE: The Central Aspergillus Data Repository (CADRE) - curatorship and
annotation of Aspergillus genomic sequence CONTACT: Dr DW Denning UNIT:
Salford Royal Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0217101266
TITLE: The effect of transmissible and non transmissible strains of Pseudomonas
aeruginosa on the chronic inflammatory response of patients with cystic fibrosis
CONTACT: Professor Anthony K Webb UNIT: South Manchester University
Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0226097944
TITLE: The epidemiology and pathogenesis of non-albicans candida species
CONTACT: Dr David W Denning UNIT: South Manchester University Hospitals
NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0226111707
TITLE: Use of substactive hybridisation to identify novel genomic regions of an
epidemic strain of Pseudomanas aeruginosa CONTACT: Professor CA Hart UNIT:
Royal Liverpool Childrens NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0206142557
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Scotland
TITLE: A case-control study of Chlamydia pneumoniae seroprevalence in patients
with Multiple Sclerosis and controls in Tayside. CONTACT: Dr JDE Parratt UNIT:
Tayside Research Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0405098697
TITLE: Analysis of RNA synthesis initiation by respiratory syncytial virus.
CONTACT: Dr Rachel Fearns UNIT: Tayside Research Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0405110201
TITLE: Beta-Lactam susceptibility of Pseudomonas aeruginosa isolates
CONTACT: Prof Sebastian GB Amyes UNIT: The Lothian University Hospitals
NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0519141412
TITLE: Development of monocyte/macrophage-based delivery of aniprotease genes
in ventilator associated pneumonia. CONTACT: Dr A John Simpson UNIT: The
Lothian University Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0519141439
TITLE: Evaluation proposal for the Arbroath/Friockheim Influenza Project.
CONTACT: Dr M A Roworth UNIT: Tayside Research Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0405091413
TITLE: Invasive pneumococcal disease in Scotland CONTACT: Mr M H Kyaw
UNIT: Chief Scientist Office
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0470113888
TITLE: Prospective evaluation of surveillance using multiplex PCR for respiratory
viruses in patients following haemopoietic stem cell transplantation. CONTACT: Dr
Anne Parker UNIT: North Glasgow University Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0394088082
TITLE: Regulation of respiratory syncytial virus nucleocapsid activity and transport
in infected cells. CONTACT: Dr R Fearns UNIT: Tayside Research Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0405103496
TITLE: Roles of CIS-acting sequences in the initial events of respiratory syncytial
virus transcription and genome replication. CONTACT: Dr Rachel Fearns UNIT:
Tayside Research Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0405109057
TITLE: The Development/Implementation and Evaluation of a Tayside Critical Care
Pathway for the Management of Community Acquired Pneumonia. CONTACT: Dr
Gavin D Barlow UNIT: Tayside Research Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0405103507
TITLE: The implementation and evaluation of a Tayside Citical Care Pathway for
the mangement of Community-Acquired Pneumonia CONTACT: Dr Gavin Barlow
UNIT: Chief Scientist Office
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0470116716
TITLE: The molecular ecology of virulence genes in S. pneumoniae CONTACT: Dr
Andrew John Smith UNIT: Chief Scientist Office
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0470100372
TITLE: The Positive Predictive Value of a Molecular Virological Diagnosis in
Patients with Respiratory Medicine CONTACT: Dr W Carmen UNIT: Lanarkshire
Acute Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0399128996
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South East
TITLE: A randomised controlled trial of interventions to reduce antibiotics
prescribing for respiratory tract infections in primary care CONTACT: Dr Paul Little
UNIT: NHS Executive South East
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0463106326
TITLE: Familial susceptibility to severe respiratory infection during childhood.
CONTACT: Dr Tessa Goetghebuer UNIT: Oxford Radcliffe Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0176104248
TITLE: Genetic analysis of the basis for host susceptibility to Invasive
Pneumococcal Disease MREC/00/5/11 CONTACT: Dr Derrick W M Crook UNIT:
Oxford Radcliffe Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0176113575
TITLE: Oxford Childhood Infection Study CONTACT: Professor David Mant
UNIT: Bury Knowle Health Centre
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0293115699
TITLE: Part 1 Sickness Absence. Influenz immunization in health care workers
CONTACT: Dr Julia Smedley UNIT: Southampton University Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0231117492
TITLE: Pneumococcal Pneumonia in Childhood CONTACT: Prof E Richard
Moxon UNIT: Oxford Radcliffe Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0176104305
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South West Region
TITLE: A double blind crossover study of long-term clarithromycin in the treatment
of bronchiectatic patients infected with Pseudomonas aeruginosa. CONTACT: Dr R
Howe UNIT: North Bristol NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0234095381
TITLE: A novel method to study the effect of low-dose macrolides on clinical
Pseudomonas aeruginosa isolates. CONTACT: Prof A P MacGowan UNIT: North
Bristol NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0234135793
TITLE: A novel method to study the effects of low-dose macrolides on clinical
pseudonomas aeruginsoa isolates. CONTACT: Dr R Howe UNIT: North Bristol
NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0234135866
TITLE: Bordetella pertussis study CONTACT: Dr DAB Dance UNIT: Plymouth
Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0185109371
TITLE: Comparison of oral moxifloxacin versus standard IV and oral comparator
regimen (beta-lactam and macrolide) in the treatment of Community Acquired
Pneumonia (CAP) CONTACT: Dr D L Smith UNIT: North Bristol NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0234104403
TITLE: Mucosal Lung Defence in Children with Respiratory Syncytial Virus
Bronchiolitis CONTACT: Dr H Duncan UNIT: United Bristol Healthcare NHS
Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0264098320
TITLE: The WARM study. Risk factors for hospitalisation among older people with
acute respiratory disease during the winter CONTACT: Dr J I Hawker UNIT: Avon
Primary Care Research Collaborative
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0632134634
TITLE: Use of Chlorhexidine gluconate 0.2% oral rinse (CHX) to reduce the
incidence of nosocomial lower respitarory tract infections in intubated ICU adult
patients. CONTACT: Ms Jacqueline Bailey UNIT: Plymouth Hospitals NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0185116743
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Trent Region
TITLE: A multicentre open pilot study CONTACT: Prof Robert Read UNIT:
Sheffield Teaching Hospitals NHS Foundation Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0059108281
TITLE: A partially observer-blind, randomised, controlled, dose ranging, singlecentre, phase I study to evaluate safety, tolerability, and immunogenicity of 2 doses,
administered by nasal route of LTK63 adjuvanted influenza vaccine, containing 3
ascending CONTACT: Prof Karl Nicholson UNIT: University Hospitals of Leicester
NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0123138281
TITLE: A prospective randomised open-label controlled trial to compare the safety,
tolerability & efficacy of influenza virus vaccine, trivalent, types A+B live coldadapted (CIAV-T) with inactivated influenza vaccine trivalent type A & B in adults
aged 60 CONTACT: Dr Stephen Green UNIT: Sheffield Teaching Hospitals NHS
Foundation Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0059103674
TITLE: A Prospective, Randomised, Open-label, Controlled Trial to Compare the
Safety, Tolerability and Efficacy of Influenza Virus Vaccine, Trivalent, Type A&B,
Live, Cold-Adapted (CAIV-T) with Influenza Virus Vaccine CONTACT: DR A H
Finn UNIT: Sheffield Childrens Hospital NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0220111020
TITLE: A questionnaire study examining the uptake and attitudes towards the
influenza vaccination among health care staff working with older people.
CONTACT: Miss E C Prince UNIT: Queens Medical Centre University Hospital
NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0192119066
TITLE: A Randomised Controlled Trial of Oral Versus Intravenous Inpatient
Treatment for Community Acquired Pneumonia I Children CONTACT: Professor TJ
Stephenson UNIT: Queens Medical Centre University Hospital NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0192107553
TITLE: A randomised controlled trial of oral versus intravenous inpatient treatment
for community acquired pneumonia in children. CONTACT: Dr T Stephenson
UNIT: Nottingham City Hospital NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0170120482
TITLE: A study to investigate the optimal dosage and efficacy of a novel nasally
administered influenza vaccine formulation in volunteers. CONTACT: Dr Robert
Read UNIT: Sheffield Teaching Hospitals NHS Foundation Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0059096443
TITLE: An evaluation of the performance of near patient tests for influenza and their
application for clinical decision making in Primary Care; a pilot study. CONTACT:
Dr A C Hayward UNIT: Queens Medical Centre University Hospital NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0192090479
TITLE: An investigation of the kinetics of pro-inflammatory cytokine gene
expression in respiratory epithelial cells in response to respiratory synctial virus
(RSV) CONTACT: Dr G S Evans UNIT: Sheffield Childrens Hospital NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0220093134
TITLE: Burden of influenza in infants and young children (Wyeth CONTACT: Dr
Karl G. Nicholson UNIT: University Hospitals of Leicester NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0123129138
TITLE: Evaluation of PCR, culture and serology for the diagnosis of chlamydia
pneumoniae in community-acquired pneumonia in South Yorkshire CONTACT: Dr
Adrian Eley UNIT: Sheffield Teaching Hospitals NHS Foundation Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0059108262
TITLE: Genetic characterisation of a novel putative virulence determinant of
streptococcus pneumoniae CONTACT: Dr Robert Read UNIT: Sheffield Teaching
Hospitals NHS Foundation Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0059096332
TITLE: Interaction of bacterial pathogens with human nasal mucosa in vitro
CONTACT: Prof Robert Read UNIT: Sheffield Teaching Hospitals NHS
Foundation Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0059096289
TITLE: Multicentre study of the epidemiology, clinical characteristics, and burden of
respiratory syncytial virus (RSV) infection in community-dwelling elderly (>65 years
of age), and 50-64 year-old patients. (Aventis Pasteur CONTACT: Dr Karl G.
Nicholson UNIT: University Hospitals of Leicester NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0123129143
TITLE: Phase I/II studies of influenza H9N2 vaccine (Department of Health
CONTACT: Dr Karl G. Nicholson UNIT: University Hospitals of Leicester NHS
Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0123129135
TITLE: PIVOT Trial - Pneumonia Intravenous Versus Oral Treatment. A
randomised controlled trial of oral versus intravenous treatment for children with
community acquired pneumonia treated as inpatients. CONTACT: Dr Helen
Sammons UNIT: Derby Hospitals NHS Foundation Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0077117135
TITLE: PREPARING FOR THE NEXT PANDEMIC A randomised, double-blind,
dose-ranging, multicentre, phase II study to evaluate the safety, tolerability and
immunogenicity of adjuvanted and non-adjuvanted influenza A/Hong Kong/1073/99
(H9N2) vaccines, containing CONTACT: Dr Karl G. Nicholson UNIT: University
Hospitals of Leicester NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0123124610
TITLE: Randomised Double Blind Study to Compare Efficacy & Safety of
Faropenem Daloxate (BAY 56-6854) 300mg PO BID For 10 days with CoAmoxiclav 500/125mg PO TID for 10 days in treatment in adult patients with
bacterial community-acquired pneumonia CONTACT: Prof Robert Read UNIT:
Sheffield Teaching Hospitals NHS Foundation Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0059096450
TITLE: Risk factors for hospitalisation due to RSV bronchiolitis CONTACT: Dr Ian
Sabroe UNIT: Sheffield Teaching Hospitals NHS Foundation Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0059118259
TITLE: Systematic review and economic modelling of the use of neuraminidsase
inhibitors for the prevention and treatment of influenza A and B (Health Technology
Assessment Programme, Department of Health CONTACT: Dr Karl G. Nicholson
UNIT: University Hospitals of Leicester NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0123129136
TITLE: The Effects of Respiratory Syncytial Virus on Antigen Presenting Cells in
Infant Bronchiolitis CONTACT: Dr G S Evans UNIT: Sheffield Childrens Hospital
NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0220102499
TITLE: The WARM study. Risk factors for hospitalisation among older people with
acute respiratory disease who seek medical attention during the winter. A case
controled study CONTACT: Ms Rachel Jordan UNIT: Southern Derbyshire Primary
Care Trusts RM&G Collaborative
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0640147824
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Wales
TITLE: A study using cough swabs and a urine sample to help us diagnose
pneumonia more accurately CONTACT: Dr Carol Sullivan UNIT: IMH Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0044126057
TITLE: Barriers to influenza immunisation in older people CONTACT: Dr Meirion
Evans UNIT: Wales Office of Research and Development for Health and Social Care
http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0048100282
TITLE: Diagnosis of Pneumococcal Pneumonia by Polymerase Chain Reaction
CONTACT: Dr D McCracken UNIT: South Bro Taf R&D Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0054100602
TITLE: Mycobacterial Immunisation In Neonates At Risk Of Atopy CONTACT:
Professor Julian Hopkin UNIT: IMH Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0044074755
TITLE: Non-bronchoscopic non directed lavages (NBL) in the diagnosis of ventilator
associated pneumonia (VAP)in the Neonatal Intensive Care Unit. CONTACT: Dr P
Buss UNIT: Gwent Healthcare NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0026114120
TITLE: The Effect of Anabolic Hormone Treatment and Muscle Training on Body
Composition and Inspiratory Muscle Function in Adults with Cystic Fibrosis and
Chronic Pulmonary Infection with Pseudomonas Aeruginosa. CONTACT: Professor
D J Shale UNIT: South Bro Taf R&D Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0054106199
TITLE: The impact of respiratory viral infections on Cystic Fibrosis patients
CONTACT: Dr Doull Doull UNIT: Wales Office of Research and Development for
Health and Social Care
http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0048119659
TITLE: The Impact of Respiratory Viral Infections on Cystic Fibrosis Patients.
CONTACT: Dr. I.J.M. Doull UNIT: South Bro Taf R&D Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0054117533
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West Midlands Region
TITLE: A study to determine the burden of virologically confirmed influenza and
respiratory syncytial (RSV) infection amongst medical patients admitted to hospital
following an acute respiratory illness. CONTACT: Dr J Gray UNIT: North
Staffordshire Research and Development Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0158108029
TITLE: A study using cough swabs and urine samples to guide management of
community acquired pneumonia in children in Shrewsbury and Swansea.
CONTACT: Dr Andrew Cowley UNIT: Shrewsbury and Telford Research and
Development Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0375119208
TITLE: Does influenza vaccination protect against cardiovascular disease? A pilot
study CONTACT: Dr Johnathan Mant UNIT: (MidReC) Midland Research Practices
Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0138129732
TITLE: Factors affecting admission to hospital with pneumonia in the West
Midlands, with special reference to metal-working CONTACT: Professor RA
Stockley UNIT: University Hospital Birmingham NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0265006511
TITLE: Genetic Diversity and Gene Expression in Pseudomonas Aeruginosa
CONTACT: Professor Chris Dowson UNIT: University Hospitals Coventry and
Warwickshire NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0295122852
TITLE: Investigation of the therapeutic actions of human recombinant interferongamma on the immune response of patients suffering from non-tuberculous
mycobacterial infections. CONTACT: Dr P Lane UNIT: University Hospital
Birmingham NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0265147248
TITLE: Non-invasive alternatives to bronchoscopy and bronchoalveolar tavage in the
investigation and diagnosis of pulmonary diseases CONTACT: Dr D Thickett UNIT:
University Hospital Birmingham NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0265110607
TITLE: Pilot study to investigate the impact of influenza and respiratory syncytial
viruses on adult hospital admissions during the winter of 2001 - 2001. CONTACT:
Dr Husam Osman UNIT: Birmingham Heartlands and Solihull NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0046105058
TITLE: Risk Factors for hospitalisation Among Older People with Acute Respiratory
Disease During the Winter (WARM Study) CONTACT: Dr Jeremy Hawker UNIT:
(MidReC) Midland Research Practices Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0138103401
TITLE: The aetiology and clinical course of acute bronchitis in the community and
the value of a 5 point colour chart as a diagnostic aid Protocol CONTACT: Dr S Hill
UNIT: University Hospital Birmingham NHS Trust
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0265109331
TITLE: Use of spirometry filters as a method of obtaining lower respiratory trace
bacteria, compared with cough swabs and sputum, in children with cystic fibrosis.
CONTACT: Dr Jane Hartley UNIT: Shrewsbury and Telford Research and
Development Consortium
http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0375119210
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