DEPARTMENT OF DERMATOLOGY Faculty Administration Luis A. Diaz, MD, The C.E. Wheeler Jr. Distinguished Professor & Chair Emma Beckham Associate Chair For Administration Robert A. Briggaman, MD, Emeritus Craig N. Burkhart, MD Donna Culton, MD, PhD Amy W. Fox, MD Lowell A. Goldsmith, MD, MPH, Emeritus Puneet Jolly, MD, PhD Ning Li, PhD Zhi Liu, PhD Aida Lugo-Somolinos, MD Patricia Mauro, MD Bradley Merritt, MD Dean S. Morrell, MD James B. Patterson, MD, PhD, Emeritus Ye Qian, PhD David S. Rubenstein, MD, PhD Susan R. Runge, MD Nancy E. Thomas, MD, PhD Rajat Varma, MD 405 Mary Ellen Jones Building University of North Carolina Chapel Hill, N.C. 27599-7287 Phone: 919-966-0785 Fax: 919-966-3898 http://med.unc.edu/derm Research Laboratories Dermatology and Skin Cancer Center Suite 405, CB 7287 Mary Ellen Jones Building Phone: 919-843-6756 Appointments 919-966-2485 Immunodermatology Southern Village 410 Market Street, Suite 400 Chapel Hill, N.C. 27516 Fax: 919-966-6460 Luis A. Diaz, MD Donna Culton, MD, PhD Phone: 919-843-5401 Fax: 919-843-5766 Dermatopathology Daniel Zedek, MD 414 Mary Ellen Jones Building University of North Carolina Chapel Hill, NC 27599-7287 Phone: 919-966-0786 Fax: 919-843-2530 Welcome to UNC Pediatric Dermatology The primary objectives of your experience include: 1. learn effective management of pediatric atopic dermatitis 2. learn effective management of acne vulgaris 3. learn the appropriate classification and management of pediatric vascular lesions 4. learn the appropriate classification and management of pediatric melanocytic nevi 5. learn the appropriate management of cutaneous infections including impetiginization, molluscum contagiosum, verrucae, herpes simplex, etc 6. appreciate the role of a dermatologist in your care of patients You will be a member of our team which can include dermatology, pediatric, and family medicine residents. As a team, our goal is to provide timely, courteous, safe, and appropriate care to the patients. While we work, we all aim to learn from each other (residents are always teaching faculty) and have fun. You will be expected to see patients after the nurses have appropriately checked the patient into a room. We use google Docs to keep track of patients once they are checked in. To access this document, go to gmail and login under the username “uncdermclinic” with password “tarheels1”. Select the “drive” heading (at the top of the page) and select the file “DO NOT CLOSE”. Once open, you will see the names of the attending physicians who are having clinic that day. There are three columns for each clinic; the left-most column is the room number, the middle column is the patient’s initials and first three numbers of their MR and the right-most column is where you put your initials to signal that you are going to see this patient. You will know that the patient has been checked in by nursing and ready for you when a room number appears in the left-hand column. Once you are signed up for a patient and the room number is present beside that patient, grab that chart, see the patient, and return to the resident’s room to present the patient to the attending. Remember that there may be a queue for presenting to the attending so ask your fellow residents working the same clinic if they are waiting to present. As some of our patients are new to an academic setting, please introduce yourself and begin similar to: “Hello, I am Dr. Smith. I am working with Dr. Morrell. I will start collecting information and exam you/child’s name, then bring in Dr. Morrell.” Obtain a problem focused history and find out the evolution and potential treatments previously utilized. Perform an examination to the degree that you feel comfortable. Return to the “write-up” area and wait to present to Drs. Morrell or Burkhart. In your presentation, focus on primary lesions and generate a differential list. Don’t fear being incorrect; in medicine we always will miss diagnoses during and after our training. After the resident/attending team has decided on management and follow-up, you’ll exit the room and enter prescriptions and diagnoses into Webcis. Allow the attending physician to complete the coding sheet. As you leave the room, make sure that the patient knows to wait for the nurse to bring them their discharge/summary paperwork. Please enter any medications that the patients require into Webcis but do not send it to the pharmacy unless your attending physician requests that you do so. Most of us prefer to send it from our account so that any questions/refill requests are clearly linked to our clinic. Please also enter the patient’s diagnoses into “problems” in Webcis and then finalize the clinical summary. Edit the clinical summary to include only the diagnoses that we have directly addressed during the visit and only the medications that we are managing as a result of those diagnoses. Once you have entered the patient’s medications, diagnoses and finalized the clinical summary, place the blue summary sheet (filled out with when to return to clinic and any specific instructions for the patient) that comes in each patient folder in the file holder on the nursing desk counter. This will let the nurses know to print the patient’s clinical summary and discharge them from the room. If the patient is going to follow up in 2 months or less time, detach the white top copy of the billing sheet and place it with the blue sheet at the nursing desk. If their follow up is more than two months, place both the yellow and the white copy together in the “completed encounters” cubby in the work room (ask someone to help you find it). Once you have placed the blue sheet at the nursing desk, enter your initials into the googledocs spreadsheet to see the next available patient. At the end of clinic (or between patients if we are not busy and there are no patients waiting), dictate a clinic note using clinic phones and the 843-4000 escription number. You will need your physician code, patient’s medical record number, and a code for the clinic visit. Document any prescriptions given on the clinic note, making sure to record strength and vehicle (cream, gel, ointment, etc). You can also directly enter the notes into Webcis if you prefer. New patients: 321901 Return patients: 321902 2 When you proofread the notes on Webcis, please add any follow-up information (biopsy results, lab results, etc can be “copied and pasted” as an addendum) at the end of the note. Use the “Ctrl + C” keys to copy and “Ctrl + V” keys to paste. If at any time you receive calls from patients or pharmacists regarding patients that you have seen in the dermatology clinic, please forward those calls to the clinic phone line at 919-966-2485. Simply tell the patient or pharmacist that you are no longer in that clinic and Dr. Morrell/Burkhart needs to be aware of the question/concern/refill request. We appreciate your involvement in our clinic and hope that it will be an informative experience. Your Residency Coordinator will have a couple articles regarding common conditions for your reading. Please utilize our textbooks and dermatology residents as sources of information and/or guidance. Included in this introduction is our therapeutic approach to atopic dermatitis and acne, frequently asked questions, and a brief medication guide. Contact information: Dermatology Residency Coordinator (Cherie Ezuka) 843-5539 Cherie_ezuka@med.unc.edu Dermatology Clinic front Desk 966-2485 Dermatology Write-up room (for physicians only) 966-2483 Dean Morrell’s pager 969-0441 morrell@med.unc.edu Clinic Appointments 966-2485 Dermatology consults (In-patient) 216-6360 Commonly asked questions What do I need for clinic? The most important thing you need is a WEBCIS account (physician number and password). Without this, you will be unable to dictate, check lab/pathology results or sign your clinic notes. Optional (but useful): pocket calculator, penlight, magnifying glass, digital camera How do I go about seeing patients? After you grab a chart, first see if they are a new patient or follow-up. If they’re a follow-up, review prior notes on WebCis. If the patient is a follow-up, note the date of the last visit, take a quick look through the HPI, and review the assessment/plan. When you see the patient, review that they followed the plan as instructed. Inquire if their condition is better/worse/same. If they’re on systemic meds, ask about pertinent ROS to check for adverse reactions. If they have a skin cancer history, ask about new/concerning lesions. For new patients, in addition to the HPI, you’ll also need to ask about PMH, meds, allergy, SH, FH, and ROS. We collect pertinent parts of this history with the new patient intake sheet (pink) included in the chart so that you can review it and follow up on things as needed. If the patient has been referred from another clinic, get the info on the referring doctor so we can send a note to the appropriate physician/clinic and include this information in the HPI. Examine the patient as appropriate. Then tell the patient that you will return with the attending, that the attending will examine them too (otherwise, they may get dressed), and that diagnosis and management will be discussed at that time. IMPOTANT NOTE: Ask the patient at this point whether it’s OK for medical students/visiting physicians to come in. History/Physical/Management What general advice do you have about the patient interview? For a new patient, after you introduce yourself, it’s a good idea to let them know that you’re working with the attending. Otherwise, they’re often confused and think they’re seeing you instead of the attending. Ask everyone about amount of sun exposure (outdoor work/hobbies, tanning beds, or sunbathing), sunscreen use, and use of wide-brimmed hats. This is the preventive medicine obligation for our field. For patients with a history of skin cancer, ask about new, changing, or concerning lesions. If there are concerns, ask about noted changes, itching, burning, bleeding or crusting. PMH and medications are especially important to review if you think their complaint could be a manifestation of systemic disease or due to drug reaction. Always confirm the patient’s drug allergies. Social history: Find out how far away patients live because this influences management/follow-up. Family history: Ask about history of melanoma and non-melanomatous skin cancer; for suspected atopic dermatitis, ask about FH of atopy, asthma, and hayfever. Family history can also be important for suspected autoimmune dermatoses and obviously, genodermatoses. ROS: Especially important for patients with history of melanoma and patients being treated with systemic medications. What should I keep in mind during the physical exam? A full body exam will usually not include breasts and genitalia unless the patient has specific complaints about these areas (ask them). If you need to examine these areas in an older kid, ask for chaperone from the staff. You can use your own good judgment for these situations but when in doubt, it’s always safer to have a chaperone especially if parents are not present. If it’s scaly, consider scraping it for KOH. Check hair, nails, and oral mucosa as appropriate. Check lymph nodes for patients with history of melanoma, evaluation of tinea capitis, or suspicion of infectious lesion. When checking for pigmented lesions, remember to look in scalp, on soles of feet, and between toes. When checking for non-melanomatous skin cancers around the head and neck, look carefully in all the “nooks and crannies” (behind ears, within the auricle, corners of eyes/nose/mouth). Wear gloves as appropriate (HIV+; exam of genitals, axillary/inguinal lymph nodes, mouth; potential fluid contact). We need to check labs. What do I do? Laboratory order sheets are in the patient rooms and also at the nurses’ station. Check off the labs you need and place the patient sticker on the order sheet. Have the attending you are working with sign the sheet and place their MD code at the bottom so that the lab results will be sent to them. Place this order sheet at the nursing station at the end of the visit with the blue sheet. 4 Tell the patient that the nurse will send them to the lab when she/he comes back with their summary sheet. Our lab for blood draws is at our checkout. Any tips for writing out prescriptions? Always make sure you prescribe the appropriate quantity and make sure you ask the attending how much to give if you are unsure. We usually specify the number of grams of creams/gels/ointments that we want the pharmacy to dispense. Without this information the pharmacy will often dispense the smallest tube possible and it is insufficient for most of our patients. Specify the location (hands/face/arms) whenever possible in the instructions for topical medications. Give appropriate number of refills to at least cover the interval until their next visit. Dictation When do I dictate/enter my clinic notes? It depends on the flow of clinic and the type of patients you end up seeing (new vs. established; complicated vs. simple). Sometimes, you won’t have time to dictate any notes until the end of clinic if you’re doing many procedures, the attending is seeing patients quickly, and all the patients show up. At other times, you’ll be able to dictate some notes during clinic if there’s a queue to present to the attending or patients are not showing for their visit. How do I dictate the clinic note? Everyone has their own style and you’ll develop you own after enough repetition, but here are the basic instructions to get you started: Dial (84)3-4000 Enter the first 5 digits of your physician code and press # Enter 321901 for new/consult patient or 321902 for established patient and press # Enter the patient medical record number (without the check digit) and press # Begin dictating. As an example: “This is resident _______ dictating a clinic visit note for patient Jane Doe, medical record #123-45-67. The date of visit was ______ and the attending was Dr. _____. The reason for the visit: ______ (ex. new patient with complaint of rash; follow-up of acne treated with Accutane). History of the present illness: The patient is a ___ year old female whose last visit was _____ weeks/months/years ago on ______.” Use the last clinic note and any notes you jotted down to finish the HPI. For a consult visit, dictate the referring physician information prior to the reason for visit. Also, the consult must be acknowledged in the reason for visit or HPI section of the clinic note. As an example: “The patient is a ___ year old female seen in consultation at the request of Dr. _____ (or clinic/practice) by Dr. _____ for evaluation of _____.” Dictate PMH, meds, allergy, SH, FH, ROS. For new patients/consults, it’s best to be more complete with these details since it’s also necessary for coding. For follow-up patients, it’s OK to use the term “reviewed and updated” for PMH and meds. Try to always dictate the drug allergies. Also, try to redictate SH and FH info from the last clinic note so it gets passed along because your note will become the last visit note being pulled for the next follow-up. Dictate the physical exam. As an example: “General: Well developed, well nourished, alert and oriented, pleasant, black female, in no acute distress. Skin: Exam of the scalp, head, neck, back, chest, abdomen, upper and lower extremities was performed and remarkable for…..(address all complaints you’ve dictated in the HPI; note that you don’t have to dictate into the HPI every single complaint the patient reports if the complaints are about numerous minor/benign lesions). Lymph nodes: negative for lymphadenopathy Laboratory data: KOH positive for hyphae Vitals: (if recording weight, temperature, BP)” Dictate the assessment and plan. As an example: “1. Acne vulgaris: Will continue current regimen of ----------, or discontinue AAAAA and add BBBBBB. 2. Warts: 6 lesions treated with liquid nitrogen. 3. Follow-up in 2-3 months for re-evaluation.” Press 8 if you have more notes to dictate, or press 5 if you’re finished dictating. In either case, you will receive a confirmation number. Record this on the second page (body part pictures) of the clinic template sheets, then sign and date that sheet. You can keep the pink copy for reference if you would like. If you are using direct entry, adhere to the same general note outline described above. Follow-Up Responsibilities The biops/laby results are back. What do I do? The Attending will call the patient and give them the results. When you proof and sign your notes on Webcis, copy and paste an addendum at the end of the note regarding lab or biopsy results. Use the “Ctrl + C” keys to copy and ““Ctrl + V” keys to paste. How do I handle prescription refill requests? Direct the patient or pharmacist to call the Derm Clinic at 966-2485. How do I refer a patient other subspecialties? Fill out a form for referral request and place in the appropriate cubby in the write-up room. Ask where it is and we will tell you. Dermatology Pharmacopoeia Treatment of Molluscum Contagiosum Body: Cantharidin for younger patients and Cantharidin or liquid nitrogen for older patients. Cantharidin needs to be washed off in 4 hours or whenever a blister forms (whichever comes first). Face and groin: Aldara cream three times per week. Treatment of Hemangiomas (Rapidly growing/ulcerating/deforming) Oral propranolol 2-3mg/kg divided BID. We usually start at 2mg/kg and then see them back on one month to increase toward 3mg/kg if all is going well. Therapy is ideally started in the first three months of life and continued to 9-12 months age. Acne, Topical Antibiotics/Antiseptic BPO Typically no insurance coverage but many OTC formulations are available (wash, gel, creams, etc). 6 Sodium sulfacetamide (Klaron) 10% Lotion (59 ml) Clindamycin/BPO (Benzaclin, Duac) 1% clinda/5% BPO gel (25 gm- Benzaclin, 45 gm Duac) Clindamycin (Cleocin T) 1% soln (30, 60 ml) lotion (60 ml) gel (30, 60 gm) Erythromycin (Akne-mycin) 2% oint (25 gm) soln (60 ml) Metronidazole (Metro –cream, -gel, -lotion) 0.75% cream (45 gm) gel (30, 45 gm) lotion (60 ml) Mupirocin (Bactroban) 2% oint (1, 15, 30 gm) Chlorhexidine (Hibiclens) 4% cleanser (15, 120, 240, 480, 960, 3840 ml) Retinoids (Topical): In order of increasing strength (Avita) Tretinoin 0.025% cream, gel (20, 45 gm) (Differin) Adapalene 0.1% cream, gel (15, 45 gm) (Retin-A) Tretinoin 0.025%, 0.05%, 0.1% cream (20, 45 gm) 0.01%, 0.025% gel (15, 45 gm) (Retin-A Microgel) Tretinoin 0.04%. 0.1% gel (20, 45 gm) (Tazorac) Tazarotene 0.05%, 0.1% cream (15, 30, 60 gm) 0.05%, 0.1% gel (30, 100 gm) Anti-fungal (Topical) Ciclopirox (Penlac for nails) 8% soln (3.3 ml) Clotrimazole (Lotrimin) 1% cream (15, 30, 45 gm); OTC (12, 24 gm) Econazole (Spectazole) 1% cream (15, 30, 85 gm) Ketoconazole (Nizoral) 2% cream (15, 30, 60 gm) 2% shampoo (120 ml) Iodoquinol/HC (Vytone) 1% cream (30 gm) Mycostatin (Nystatin) Cream (30 gm) Powder (15 gm) Terbinafine (Lamisil AT) 1% cream OTC (12, 24 gm) Anti-histamines, Anti-puritic (Oral) Cetirizine (Zyrtec) Tabs (5, 10 mg); adult 5-10 mg qd Syrup (5mg/5ml); kids 0.5-1 tsp po qd Doxepin (Zonalon) Caps (10, 25, 50, 75, 100, 150 mg); adult start 25mg qhs Concentrate (10mg/ml); kids take 1cc po qhs Fexofenadine (Allegra) Tabs (30, 60, 180 mg), Caps (60 mg); adult 60mg bid or 180mg qd Hydroxyzine (Atarax) Tabs (10, 25, 50 mg), Caps (25, 50, 100 mg); adult 10-100 mg qd-qid Syrup (10mg/5ml); kids 2mg/kg/d divided tid Loratadine (Claritin) Tabs (10 mg); adult 10mg qd Syrup (1mg/ml) Anti-perspirant/Drying Aluminum Cl hexahydrate (Drysol) 20% soln (35, 37.5, 60 ml); apply qhs Talc/microporous cellulose (Zeasorb) Powder (70.9, 312 gm) Depigmenting Agents Hydroquinone 2%, OTC (Porcelana, Palmer’s, Ambi) Hydroquinone 4% with sunscreen (Solaquin Forte) Tri-Luma (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) Emollients/Keratolytics/Moisturizers Lactic Acid (Lac-Hydrin) 5% lotion OTC 12% lotion (225, 400 ml) 12% cream (280 gm) Urea (Carmol) 10% lotion OTC 20% cream OTC 40% cream Rx Lactic acid/Urea (Eucerin Plus) 2.5% Lac/10% U cream OTC 5% Lac/5% U lotion OTC Hair Growth Finasteride (Propecia) Tab (1 mg); 1 mg qd Minoxidil (Rogaine) 8 2%, 5% soln OTC (60 ml) Hair Removal Eflornithine HCl (Vaniqa) 13.9% cream (30 gm) Pigmenting Agents/Cosmetic Cover-up (Vitiligo, Alopecia) Dihydroxyacetone Chromelin, (Summer Labs) Dy-O-Derm (Galderma) Cover-up Dermablend cosmetics (Loreal) Toppik alopecia cover-up (Spencer-Forrest) Protectants (Barrier) Zinc oxide (Desitin) 10% cream (420 gm) 40% oint (30, 60, 90, 120, 240, 240, 480 gm) Zinc oxide/Corn startch 25% paste (30, 480 gm) Shampoos Coal Tar (T/Gel) 1% shampoo OTC Ketoconazole (Nizoral) 1% shampoo OTC (Nizoral A-D) 2% shamppo (120 ml) Salicyclic acid (T/Sal) 3% shampoo OTC Selenium Sulfide 1% shampoo OTC (Head & Shoulders Intensive Care, Selsun Blue) 2.5% shampoo (120 ml) Fluocinolone (Capex) Clobetasol (Clobex) Wart Treatment Salicylcic Acid 16% soln OTC (Compound W) 17% soln, gel OTC (Duofilm) 40% plasters OTC (Mediplast, Compound W one-step) Candidal injections 0.1 cc per wart to max 1cc in patient per visit Squaric acid Protocol in clinic Wet/Crusted Lesions Aluminum Acetate Solution (Burow’s) Domeboro powder (12, 100 pkts/box) Domeboro tablets (12, 100, 100 tablets/box) [1 pkt/tablet per pint of water = 1:40 solution] Therapeutic Approach to Acne Dean Morrell, MD Modified 4/25/13 1. 2. Pathogenesis a. Microcomedo formation b. Androgen stimulation of sebaceous glands c. Normal cutaneous bacteria d. Immunogenic stimulators e. Inflammatory response Types of acne a. Superficial (comedones) i. Topical retinoids qhs ii. My retinoid therapeutic ladder “Comedo buster”, potential for irritation My entry level for all patients Least irritating, least effective Tazorac gel 0.05%, 0.1% Tazorac cream 0.05%, 0.1% Retin-A Microgel 0.1% Retin-A Microgel 0.04%, Differin 0.3% gel Tretinoin 0.025% cream, Differin 0.1% cream Differin 0.1% cream Avita cream Can add topical benzoyl peroxide qam if needed or topical dapsone (Aczone gel) Face only: gel Torso + face: wash OTC (Panoxyl), Triaz (3,6, or 9%), or Brevoxyl (4, 8, 10%) b. Deep and inflammatory (papules, pustules, cysts, nodules) i. Topical retinoids qhs ii. Topical Combo products qam to face 1. Duac gel (Clinda/benzoyl peroxide) 2. Benzaclin gel (Clinda/benzoyl peroxide) 3. EpiDuo (retinoid/benzoyl peroxide) iii. Oral antibiotics (tetracycline family) Agent Tetracycline Doxycyxline Minocycline Dosing 500 mg BID 20-100mg qd-BID 50-100mg qd-BID 10 Issues Empty stomach Sun sensitivity Lupus, autoimmune hepatitis, bluish discoloration (all if used > 1year) iv. Isotretinoin 1. 1-2 mg/kg/day, 5-7 months 2. Monitor pregnancy, LFTs, lipids Atopic Dermatitis Dean Morrell, MD Modified 4/25/13 1. Education a. Control vs Cure b. Daily bathing c. Mild to no soap d. Cotton clothing; fragrance-free products; no dryer sheets or fabric softener 2. Barrier a. White petrolatum after bathing b. Cetaphil cream next acceptable 3. Infection a. Staph aureus (cephalexin 125mg/5ml or 250mg/5ml, 30-50 mg/kg/d divided tid; clindamycin 75mg/5ml, 10-30 mg/kg/d divided tid) b. HSV (eczema herpeticum) 4. Inflammation a. Unwarranted fear of topical steroids b. Always use the weakest possible to establish control in one week c. Only use ointments d. Intermittent pulses to clear in 3-5 days e. Moisturize clear/controlled areas without steroids f. First sign of return of inflammation: i. Repeat topical steroid pulse g. If steroid doesn’t clear in 1-2 weeks, go to stronger agent (knees, elbows, hands, and feet commonly need a step up from rest of body) h. My therapeutic ladder (There are many more options; below are my workhorses. Generic forms are acceptable and effective.) Class 1 2 3 4 5 6 7 Clobetasol, Halobetasol Fluocinonide Triamcinolone 0.1% Synalar 0.025% Desonide Hydrocortisone 2.5% Hydrocortisone 0.5, 1% (These are guidelines based upon the type of patient referred to our Pediatric Dermatology clinic. If weaker steroids establish good control in 5-10 days, then go with that specific agent.) Location Face Mild Westcort Moderate/Severe Triamcinolone 0.1 Body Triamcinolone 0.1 Clobetasol 5. Pruritus a. In infants and young children, good control of skin activity usually results in discontinued scratching b. Older kids and chronic scratchers may need oral antihistamines i. Zyrtec qam (if not sedating in patient) ii. Hydroxyzine (10mg/5ml, 2mg/kg/day divided TID) given qhs iii. For recalcitrant pruritus, doxepin (10mg/1ml, 1ml NOT tsp qhs) 12