Provided by: Cardiology Grand Rounds Academic Year 2014-2015 “Role of the “periphery” in Heart Failure in Preserved Ejection Fraction” April 2, 2015 7:30 – 8:30 AM 11-146 Smilow Center for Translational Research Julio A. Chirinos, MD, PhD, FAHA Assistant Professor of Medicine Director, Cardiovascular Phenotyping Unit Clinical Translational Research Center University of Pennsylvania Target Audience This program has been designed for departmental/institutional faculty, fellows, residents, medical students, nurses, and QA/CEQI personnel in the medical specialties of cardiology, CT surgery, radiology, cv imaging, and medicine, biology engineering, pharmacology, and physiology. Educational Objectives After completing this activity, participants should be able to: Describe evidence supporting the latest treatment for cardiac conditions (ie., interventional procedures such as cardiac catheterization, cardiac biopsies, electrophysiologic studies), noninvasive cardiac procedures and clinical cardiology therapy Recognize the importance of system-based practices that explicitly depict the larger context and system of health care by stressing the importance of collaborative efforts involving physicians and ancillary staff for safety and quality improvements Assess patient care through discussing medical errors, complications and unanticipated outcomes Improve practice through reviewing records, specifics and revisiting errors to gain insight without blame or derision Review experimental data from translational and clinical studies with the potential to influence practice Assess the results of clinical trials from a regional and national point of view Accreditation The Perelman School of Medicine at the University of Pennsylvania is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Designation of Credit The Perelman School of Medicine at the University of Pennsylvania designates this live activity for a maximum of 1 AMA PRA Category 1 Credit ™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Acknowledgement of Commercial Support* NONE For more information, please contact Lynn Radnich 215-662-3140, lynn.radnich@uphs.upenn.edu Check your CME online at www.penncmeonline.com Disclosure of Relevant Financial Relationships and Unapproved Uses of Products It is policy at the Perelman School of Medicine at the University of Pennsylvania for individuals who are in a position to control the content of an educational activity to disclose to the learners all relevant financial relationships that they have with any commercial interest that provides products or services that may be relevant to the content of this continuing medical education activity. For this purpose we consider relationships of the person involved in the CME activity to include financial relationships of a spouse or partner. The intent of this policy is not to prevent expert faculty with relevant relationship(s) with commercial interest(s) from involvement in CME, but rather to ensure that Penn CME-certified activities promote quality and safety, are effective in improving medical practice, are based on valid content, and are independent of control from commercial interests and free of commercial bias. Peer review of all content was conducted for all faculty presentations whose disclosure information provided to the Penn Office of CME was found to contain relationships that created a conflict of interest relative to the topic of their presentation. In addition, all faculty were instructed to provide balanced, scientifically rigorous and evidence-based presentations. The staff in the Office of CME at the Perelman School of Medicine at the University of Pennsylvania, Mila Kostic, Director of CME and the peer reviewer Zalman Agus, MD, Associate Dean for CME, have disclosed that they have no relevant financial relationships with any commercial interests related to the content of this educational activity. The following individuals have disclosed that they have no relevant financial relationships with any commercial interests related to the content of this educational activity: PLANNING COMMITTEE MEMBER NAME DANIEL M. KOLANSKY, MD MARIA A. GUERTTY, MD, PHD PRESENTER NAME The following individuals have reported the listed relevant financial relationships with commercial interests related to the content of this educational activity. PRESENTER NAME NAME OF COMMERCIAL INTEREST RELATIONSHIP Julio A. Chirinos, MD, PhD OPKO HealthCare, Bristol Myers Squibb Fukuda Denshi, Highpoint Pharmaceuticals NIH, Veterans Affairs Admin American College of Radiology Network Consultant Consultant Research Funding Research Funding Relevant Financial Relationships: Financial relationships are those relationships in which the individual benefits by receiving a salary, royalty, intellectual property rights, consulting fee, honoraria, ownership interest (e.g., stocks, stock options or other ownership interest, excluding diversified mutual funds), or other financial benefit. Financial benefits are usually associated with roles such as employment, management position, independent contractor (including contracted research), consulting, speaking and teaching, membership on advisory committees or review panels, board membership, and other activities from which remuneration is received or expected DISCLOSURE OF UNAPPROVED USES OF PRODUCTS PRESENTER NAME JULIO A. CHIRINOS, MD, PHD PRODUCT CALCIUM CHANNEL BLOCKERS INORGANIC NITRATE ENDOTHELIN RECEPTOR ANTAGONISTS ORGANIC NITRATES/HYDRALAZINE INVESTIGATIONAL AND/OR OFF-LABEL USE USE IN HFPEF USE IN HFPEF USE IN HFPEF USE IN HFPEF