UC Irvine Environmental Health & Safety: Example
Standard Operating Procedures for Particularly Hazardous Substances
Thimerosal
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Process
General handling of Thimerosal. (Ethyl mercurithiosalicylic acid sodium salt).
Hazardous Chemicals/Class of Hazardous Chemicals
Pure form is highly toxic. Reproductive toxin. Sensitizer. Neurotoxin. Organomercurial salt.
PPE - Personal Protective Equipment
Skin and eye protection should be worn when working with Thimerosal. Goggles should be worn when
potential for splashing exists. Disposable or lightweight nitrile, neoprene, natural rubber, or PVC gloves
provide protection from incidental contact. Heavier gloves should be used when extended handling of
contaminated or preserved materials or immersion is likely. A chemical-resistant apron should be used
when transferring or using large quantities and splash is likely. Wear closed toe shoes.
Engineering/Ventilation Controls
Work with thimerosal in a fume hood or with local exhaust ventilation to avoid inhalation. Use only in an
area equipped with a shower and eyewash.
Special Handling Procedures and Storage Requirements
Read MSDS and this SOP prior to use. Store in tightly closed container. Separate from oxidizing agents.
Wash lab bench, glassware and hands thoroughly after use. Use in smallest quantities and concentrations.
Store in Room _________.
Spill and Accident Procedures
Small spills: Do not attempt clean-up if you feel unsure of your ability to do so or if you perceive the risk
to be greater than normal laboratory operation. Absorb incidental spills using damp paper towels. Collect
and transfer to EH&S for disposal.
Large Spills: Notify others in the area. Evacuate room and notify EH&S.
Eyes: Flush for a minimum of 15 minutes.
Skin: Wash thoroughly with soap & water.
Inhalation: Move to fresh air.
Seek medical assistance for further recommendations.
Waste Disposal
Place waste in labeled container with hazardous waste tag complete. Store in secondary container in
Hazardous Waste Storage Area under hood in Room ___. Dispose of through EH&S within 9 months of
container start date.
Approval Required
PI approval for initial use.
Decontamination Procedures
Wash surfaces with soap and water.
Designated Area
Bench ___ in Room ___.
For more information relevant to completing this form, review thoroughly Chemical Hygiene Plan:
Section 5.
Training Acknowledgement: I have read, asked questions, and understand the hazards of and safe
working procedures for the activity/materials described herein.
NAME
DATE
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