BIOGRAPHICAL SKETCH
Provide the following information for the Senior/key personnel and other significant contributors in the order listed on Form Page 2.
Follow this format for each person. DO NOT EXCEED FOUR PAGES.
NAME
POSITION TITLE
Ira S Adams-Chapman, MD MPH
Assistant Professor of Pediatrics
eRA COMMONS USER NAME (credential, e.g., agency login)
IADAMSC
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and
residency training if applicable.)
DEGREE
INSTITUTION AND LOCATION
MM/YY
FIELD OF STUDY
(if applicable)
Emory University
Atlanta, GA
Medical College of Georgia
Augusta, GA
Children’s Hospital Medical Center
Cincinnati, OH
University of California San Diego
San Diego, CA
Emory University Rollins School of Public Health
Atlanta, GA
BA
05/1987
Biology and Political
Science
MD
05/1991
Medicine
Resident
Fellowship
MPH
07/199107/1994
07/199507/1998
08/200705/2011
Pediatrics
Neonatology
Health Outcomes
A. Personal Statement
My clinical and research interests are focused on the neurodevelopmental (ND) follow-up of prematurely born
infants and how specific neonatal morbidities modify outcome. My research activity has focused on patients
with intraventricular hemorrhage and/or periventricular leukomalacia and those with infectious complications of
prematurity. Those patients with a history of necrotizing enterocolitis and/or surgical short bowel syndrome
represent an extremely high risk subset due to the associated systemic inflammatory response from the
primary disease and their compromised nutritional status. Current projects evaluate the ND outcome of ELBW
infants with systemic candidasis, Language outcomes of ELBW infants using the Bayley III and Nutrition and
Neurodevelopmental Outcomes of Neonates with Intestinal Failure.
In addition to being the principal investigator for our site in the NICHD Neonatal Research Network Follow-Up
Project, I am also the medical director of our developmental follow-up program and have been committed to
elevating the scope and level of service provided to our patients. We have systematically worked to improve
both process and output during my tenure. It is clear that both sociodemographic and medical risk factors both
impact long term neurodevelopmental outcome. My research activities are an extension of my clinical duties.
Education of both residents and fellows is an important part of my role as medical director for the follow-up
clinic. I am able to have direct interactions with our trainees and have developed supplementary training
materials to augment their knowledge of neurodevelopmental outcome in this population, including an
interactive educational module.
Future directions are focused on development of a joint developmental/GI clinic for our patients with short
bowel syndrome through cooperative efforts with our division of Gastroenterology and Pediatric Surgery. We
plan to systematically evaluate growth, nutrition and the neurodevelopmental outcome of this subset of
patients. I also plan to translate many of the skills learned in the MPH program to guide system based quality
improvement projects within our neonatology division.
B. Positions and Honors
Positions and Employment
PHS 398/2590 (Rev. 06/09)
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7/91-7/94
7/94-7/95
7/98-9/98
7/95-7/98
1998-present
2002-present
5/09-5/10
Pediatric Internship/Pediatric Residency
Children’s Hospital Medical Center, Pediatrics
Cincinnati, OH
Staff Physician
Children’s Hospital Medical Center, Pediatrics, Division of Neonatology,
Cincinnati, OH
Staff Physician
Children’s Hospital San Diego, Division of Neonatology/CAMG
San Diego, CA
Neonatology Fellowship
University of California San Diego, Department of Pediatrics, Division of
Neonatology, San Diego, CA
Assistant Professor of Pediatrics
Emory University School of Medicine, Department of Pediatrics/Division of
Neonatology, Atlanta, GA
Medical Director, Developmental Progress Clinic
Emory University School of Medicine, Department of Pediatrics/Neonatology,
Atlanta, GA
Consultant
Research Triangle Institute International
Research Triangle, Park, NC
Honors:
Outstanding Fellow Teaching Award, University of California San Diego
Outstanding Resident Award, Division of Neonatology, Cincinnati Children’s Hospital
Harry B. O’Rear Award-Outstanding Medical Student in Pediatrics
C. Selected Peer-reviewed Publications
1.
Adams-Chapman I, Vaucher YE, Bejar RF, Benirschke K, Baergen RN, Moore TR. Maternal floor
infarction of the placenta: Association with central nervous system injury and adverse
neurodevelopmental outcome. Journal of Perinatology, 2002;22:236-241. PMID: 11948388
2.
Stoll BJ, Hansen N, Adams-Chapman I, Fanaroff AA, Hintz SR, Vohr BR, Higgins RD.
Neurodevelopmental and growth impairment among extremely low birth-weight infants with neonatal
infection. JAMA, 292:2357-2365, 2004. PMID: 15547163
3. Hintz SR, Van Meurs KP, Perritt R, Poole WK, Das A, et al for the NICHD Neonatal Research Network.
Neurodevelopmental outcomes of premature infants with severe respiratory failure enrolled in a
randomized controlled trial of inhaled nitric oxide. J Pediatr. 2007 Jul;151(1):16-22, 22.e1-3. PMID:
17586184
4. Adams-Chapman I, Hansen N, Stoll BJ, et al: Neurodevelopmental outcome of the extremely low
birthweight infants with posthemorrhagic hydrocephalus requiring shunt insertion. Pediatrics. 2008
May;121(5):e1167-77. Epub 2008 Apr 7. PMID: 18390958
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5. Peralata-Carcelen M, Moses M, Adams-Chapman I,Gantz M, Vohr BR for the Neonatal Research
Network, NIH. Stability of neuromotor outcomes at 18 and 30 months of age after extremely low birth
weight status. Pediatrics 2009;123(4):1132-41. PMID: 19403482
6. Adams-Chapman I: Insults to the developing brain and impact on neurodevelopmental outcome. J
Commun Disord 2009. 42(4):256-62. PMID: 19423130
7. Freeman Duncan A., Watterberg KL, Nolen TL, Vohr BR, Adams-Chapman I, et al. Effect of ethnicity
and race on cognitive and language testing at age 18-22 months in extremely preterm infants. J
Pediatr, 2012. 160(6): p. 966-971 e2. PMID: 22269248
8. Pappas A, Shankaran S, Hansen NI, Bell EF, Stoll BJ, et al. Outcome of Extremely Preterm Infants
(<1,000 g) With Congenital Heart Defects From the National Institute of Child Health and Human
Development Neonatal Research Network. Pediatr Cardiol, 2012. PMID:22644414
9. Shankaran S, Pappas A, McDonald SA, Vohr BR, Hintz SR, et al for the NICHD Neonatal Research
Network. Childhood outcomes after hypothermia for neonatal encephalopathy. N Engl J Med, 2012.
366(22): p. 2085-92. PMID:22646631
10. Sood BG, Shankaran S, Schelonka RL, Saha S, Benjamine Jr DK, et al. Cytokine Profiles of Preterm
Neonates with Fungal and Bacterial Sepsis. Pediatr Res, 2012. PMID:22562288
11. Vohr BR, Stephen BE, Higgins RD, Bann CM, Hintz Sr, et al for the NICHD Neonatal Research
Network. Are Outcomes of Extremely Preterm Infants Improving? Impact of Bayley Assessment on
Outcomes. J Pediatr, 2012. PMID:22421261
12. Wynn JL, Tan S, Das A, Goldberg RN, Adams-Chapman I, et al for the NICHD Neonatal Research
Network. Outcomes following candiduria in extremely low birth weight infants. Clin Infect Dis, 2012.
54(3): p. 331-9. PMID:22144537
D. Research Support
Active
HD27851 - 2012-2017
Stoll, Barbara J, Site PI
Adams-Chapman I, Follow-Up PI
NICHD Multicenter Network of Neonatal Intensive Care Units
National Institute of Child Health and Human Development
Role: Follow-up PI
Dr. Adams-Chapman is the medical director of the Developmental Progress Clinic where
neurodevelopmental evaluations are performed for patients actively enrolled in studies performed by the
NICHD Neonatal Research Network that require neurodevelopmental assessments.
Completed Research
LIONS Study: Longitudinal iNOmax Observational Neonate Study: A study of term and near term
infants receiving INOmax Therapy. Sponsored by iNO Therapeutics. Enrollment completed
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