SURVEY AND INTEGRATION OF NEUROSCIENCE (I): THE FOUNDATION Neuroscience 5100 Daniel Barth Fall 2013 Office: Phone: Hours: MUEN E420 492-0359 (2-0359) F - 12:00-1:00 (or always by appointment) Seminar: F 10:00-11:40 AM Room: MUEN E317 Lecture: TR 9:30AM-10:45AM (820) Room: HUMN 1B80 Lab: 2 Sections - F (821/822) or W (823/824) Room: MUEN E0022 Required Texts: PRINCIPLES OF NEURAL SCIENCE, E.R. Kandel, J.H. Schwartz & T.M. Jessell, Fourth Edition , Elsevier, 2000. Download LECTURE NOTES from my Web site at http://psych.colorado.edu/~dbarth/ The Lab Manual and Lab Data Worksheet are also available at this Web site. Make sure to download my ANATOMY QUICKTIME MOVIES from this site as well. Not Required: This text is not available and therefore not required. If you can find a used copy though, get it. THE CIBA COLLECTION OF MEDICAL ILLUSTRATIONS, VOLUME I, NERVOUS SYSTEM, PART I, ANATOMY AND PHYSIOLOGY, Frank H. Netter, M.D., CIBA, 1991. SYLLABUS FOR SEMINAR MEETINGS Date AUG SEP OCT NOV DEC Topic 30 6 13 20 27 4 11 18 25 1 8 15 22 29 6 13 Presentations Organization (1) No class Anatomy Lab Anatomy Lab Anatomy Lab Anatomy Lab Anatomy Lab Seminar Lecture Detailed dissection of the sheep brain “ “ “ Practical Exam in Anatomy Electronics: The basics Additional reading: Appendix A Student presentation Student presentation NO CLASS (Society for Neuroscience Meeting) Student presentation Student presentation NO CLASS (Thanksgiving Holiday) Student presentation Student presentation (only if needed) SYLLABUS FOR LECTURE MEETINGS Date AUG SEP 27 29 3 5 10 12 17 19 24 Lecture Topic Reading Organization (1) Methods for Studying the Brain (1) Neuroanatomy (4) (pp. 98, 366-380, 913-916) 1,17,18,44,43(pp.853-856),49,50 Neurophysiology (5) 2,7,8,9,10,11,12,14,15 OCT NOV DEC DEC 26 1 3 8 10 15 17 22 24 29 31 5 7 12 14 19 21 26 28 3 5 10 12 16 Review of Neuroanatomy and Neurophysiology EXAM I Vision (5) 21,26,27,28,29 Audition (3) 30,31 Review of Visual and Auditory Systems NO CLASS (scientific meeting) EXAM II Sensory/Motor (4-5) 22,23,33,36,37,38 NO CLASS (Fall Break) NO CLASS (Fall Break) 42[if we get to the cerebellum] Review FINAL EXAM 1:30 PM - 4:00 PM HUMN 1B80 GRADING SEMINAR Laboratory Practical Presentations = = 50 points 50 points LECTURE Two Quizzes Three Exams = = 60 points 300 points TOTAL = 460 points A- to A B- to B+ C- to C+ D = = = = 90 - 100% 80 - 89.9% 70 - 79.9% 60 - 69.9% COMMENTS ABOUT THE COURSE This course is designed to provide an intensive introduction to the principles of neuroscience. It initially covers the detailed neuroanatomy of human forebrain, hindbrain and spinal cord. This is followed by neurophysiology with an additional concentration on the electrophysiology of neural systems and neural signaling. The basics of neuroanatomy and neurophysiology are then applied to an examination of the structure and function of visual, auditory, and sensorimotor systems in animal and man. ABOUT THE ORGANIZATION All students enrolled in NRSC 5100 (5 credit) must simultaneously attend all lectures and take all exams and quizzes for a section of my tandem course Behavioral Neuroscience (PSYC/NRSC 4052/5052), but not register for this later course. This combination permits a presentation of the material that is balanced between lecture and seminar formats, without wasting valuable seminar time reproducing lectures from the tandem course. While students enrolled in NRSC 5100 are not responsible for the entire laboratory section offered in PSYC/NRSC 4052/5052, the sheep brain dissection is too valuable to miss, so your first several weeks of seminar presentation will be down in the lab performing hands on dissections followed by a practical exam on this material. We then return to the seminar format for the balance of the semester. I usually take this opportunity to provide you with more advanced material that complements the basic PSYC/NRSC 4052/5052 lectures, concentrated particularly on the electrophysiology of neural systems and neural signaling. Student presentations in this seminar have been a highly successful feature in the past and I take them quite seriously. With advanced help from me, you will each prepare a typical 30 minute (20 min present, 10 min questions) presentation on select topics of your choosing that may relate to, but go beyond, the scope of material in this course. Usually (but not exclusively), the topic will be related to research you are conducting in your home lab. This exercise serves the dual purpose of teaching you how to perform a concise and clear scientific presentation while at the same time educating the rest of us about who you are and what you are up to. Further details of the student presentations will be discussed during our initial organizational meeting. Given the time commitments imposed by the breadth and depth of the subject matter, please take a minimum number of credit hours during the semester you enroll in this course. Being responsible for all of the material presented in PSYC/NRSC 4052/5052, plus all of the reading, and individual presentations in NRSC 5100, is a lot. But I assure you it is worth the time commitment, and I hope you find this one of the most challenging, interesting, and useful courses you take as a graduate student in our program. PLEASE USE MY OFFICE HOURS AND MORE! Given the variety of your backgrounds, some of you may have more of a struggle with some parts of the course than others. While class discussion may help compensate for some of this, a particular problem should be continued into my office hours. If this time is not convenient then I can always arrange another time by appointment. I consider office hours to be an integral part of teaching this course and I invite you to do the same. ENJOY!