Molecular Genetics Unit Review

Mrs. Petrany
SBI 4U Molecular Genetics Unit Review
This unit test will cover the topics from Lectures 11-15. Lectures are summaries of the information in
the textbook, therefore it is best to use them as a starting point for study notes. General concepts can be
extracted from the lecture handouts. Textbook questions that have been assigned to date are examples of (a)
how to apply general concepts to specific situations, and (b) types of questions that will appear on the test.
Multiple choice questions will be derived from weekly quiz questions, lecture notes and textbook
questions. Vocabulary for the matching terms section of the test will be taken from lecture notes
(CAPITALIZED) and the textbook (bolded in margin).
The test will be formatted in the following manner:
Part 1 - Multiple Choice - 30 questions, 1 mark each
Part 2 - Matching Terms - 20 questions, 1 mark each
Part 3 - Short Answer - 20 marks total
Total Marks for Test - 70
1. Additional Practice Questions - P. 274 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 13, 14, 18
P. 324 1-12, 13, 14, 15, 17, 18, 19, 23, 24, 26, 27, 29, 30, 34, 40
2. Terms to Review - 20 of the following terms will be on the unit test.
Glycosyl bond
Amino acid
Template strand
Housekeeping gene
Signal molecule
Complimentary base pairing
Replication fork
Coding strand
Acceptor site
Transcription factors
Repressor protein
Nitrogenous base
Replication bubble
mRNA Transcript
Peptide site
Gene regulator
Mrs. Petrany
3. Multiple Choice Review Questions – Quizzes
Molecular Genetics Quiz #1
DNA strands run in parallel opposite directions. They are _________.
A and T pair up; C and G pair up; this is called ______________ base pairing.
True or false: base pairs connect using hydrogen bonds
True or False: complimentary base pairing and hydrogen bonds are the reason DNA molecules are a
consistent 2nm wide
5. The DNA molecule is 2 helical strands…it is a _________ ___________
6. The study of living organisms to develop beneficial technology or processes:______________________
7. DNA is organized in a hierarchy because:
a. It is better that way
b. It fits in the nucleus
c. It is easier for the body to use it if it is organized
8. True or false: molecular biologists use enzymes and processes that occur naturally in bacteria to study
and manipulate DNA
9. What biotechnology equipment uses the chemical and physical properties of DNA to separate the larger
strands from the smaller strands is __________________________________.
10. An organism that has its own DNA, but lacks the machinery to replicate it…and has a symbiotic
relationship with its host organism is:
a. A vector
b. A plasmid
c. A virus
d. A competent cell
Molecular Genetics Quiz #2
1. True or false: DNA replicates semi-conservatively.
2. DNA is replicated continuously on:
a. The leading strand
b. The lagging strand
3. DNA replication takes place in:
a. The cytoplasm
b. The nucleus
4. DNA can not leave the nucleus because:
a. It would not fit through the nuclear membrane
b. It would get destroyed in the cytoplasm
5. In RNA, C bonds with G and A bonds with ____.
6. True or false: A redundancy in the genetic code minimizes replication errors by having only one codon
coding for each amino acid
7. The process that allows a copy of DNA to leave the nucleus is_________________.
8. The process that creates a protein from a strand of mRNA is __________________.
9. How many stages does each of these processes (from 7 and 8) have?
10. True or false: There is only one start codon.
Mrs. Petrany
Molecular Genetics Quiz #3
1. True or false: All proteins are required by the body at all times.
2. Any gene that is required by the body on a regular basis is called a ________________ gene.
3. True or false: Post-transcriptional processes both regulate and protect the mRNA transcript.
4. A mutation that has no effect on protein function is called a _______________ mutation.
5. Translocation mutations affect:
a) Single nucleotides
b) Multiple nucleotides
c) Multiple gene sequences
6. Name one of the causes of mutation.
7. Cytokinesis is:
a) The division of atoms
b) The division of the cytoplasm and organelles
c) The division of the nucleus
d) The division of proteins
8. Which of the following statements about the genetic code is false?
a) There are multiple start codons
b) There are three stop codons
c) Codons are always three nucleotides in length
d) One amino acid can have multiple codons
9. Which of the following would not cause a fatal mutation:
a) Mistakes made by genetic machinery
b) Mutagenic agents
c) Reading frame shifts
d) Single nucleotide change
10. If mRNA was inactive, which of the following would happen:
a) DNA replication would stop
b) Cytokinesis would not be regulated
c) No proteins would be synthesized
d) Mitosis would stop