AESCAP Venture takes 25% stake in i-Optics Amsterdam, Netherlands (November 16, 2007) - Aescap Venture has taken a 25% stake in the Dutch medtech company i-Optics. i-Optics’ eye diagnostics fulfil the need of affordable and user friendly retinal cameras. Key application of the retinal camera is screening for potentially blinding diseases like Diabetic RetinoPathy (DRP) and Macular Degeneration. Diabetes patients should be examined every year on early signs of DRP. However, in many countries less than 50% of diabetes patients are screened due to camera costs, the complexity to operate these cameras and due to the required pupil dilation, a common cause for patients to drop out of screening programs. i-Optics proprietary technology does not require pupil dilation, thus allows patients to drive home after having their eyes screened. Initial clinical validation of its prototype camera has started. The company’s lead camera product will be tested in the USA in a comparative clinical trial involving 1000 patients. Two other innovative diagnostic cameras, one for the use on infants and the other for R&D purposes, are in late stage development. Patrick Krol, partner at Aescap and chairman of i-Optics’ supervisory board, was highly impressed by the company’s patented technology and its potential: “We typically are interested to invest in medical solutions which can decrease healthcare costs. It’s still very hard to find proprietary technology that is both broadly applicable and will reduce costs dramatically. i-Optics is one of these rare cases”. Contacts: Aescap Venture Management BV Patrick Krol Strawinskylaan 629 World Trade Center B-Toren Amsterdam T: +31(0)20 570 2940 F: +31(0)20 673 7846 E-mail: pkrol@aescap.com www.aescap.com i-Optics BV Michiel Mensink Rotterdamseweg 145 2628 AL Delft T: +31(0) 6 242 1247 F: +31(0) 15 278 8842 E-mail: mensink@i-optics.net www.i-optics.net About Aescap Venture Aescap Venture is a venture capital firm focusing on the creation and growth of European biomedical companies. Through early and active involvement in the companies, Aescap Venture will achieve an accelerated development of its portfolio companies and their products. Aescap Venture Fund I has € 103 million under management. The founders of Aescap are Michiel de Haan, the founder and CEO of Atlas Venture until 2000 and Dinko Valerio PhD, the founder and former CEO of Crucell, a Euronext / NASDAQ-listed biotechnology company. Additional Partners are Patrick Krol MBA, a successful entrepreneur and expert in Life Science marketing and business development and Kreske Nickelsen MSc/MBA, previous Director at 3i, with 10 years of experience in European Life Science venture capital. For more information, visit www.aescap.com About i-Optics BV i-Optics has invented and developed an affordable, high-quality and patientfriendly retina camera. i-Optics was established in 2003 in Delft, The Netherlands, by ex McKinsey Michiel Mensink. By the end of that year i-Optics proved the feasibility of the retinal imaging technology. With funding from the Dutch and US government, a small, portable prototype has been developed. Two other innovative diagnostic cameras, one for the use with infants and the other for use in pharma R&D, are in late stage development. For more information, visit www.i-optics.net