Xun et al – supplementary data Supplementary Figure 1 a Supplementary Figure 1 b 1 Xun et al – supplementary data Supplementary Figure 1 c Supplementary Figure 1. Meta-analysis of IL4 and IL13 polymorphisms association with GD measured by allele frequency data. Black squares (OR) and 95% CI (bar) are shown for each study. The pooled ORs and their 95% CIs are represented by the shaded diamonds. Summary ORs are given for each group as well as all groups combined. Meta-analysis was performed using Review Manager software (version 4.2) (http://www.cc-ims.net/RevMan/). (a) Meta-analysis for IL4-T-590C (rs2070874) using a fixed effects model, n indicates the total number of C alleles, N indicates the total number of T plus C alleles; (b) Meta-analysis for IL13-C-1112T (rs1800925) using a random effects model, n indicates the total number of C alleles, N indicates the total number of T plus C alleles; and (c) Meta-analysis for IL13-G2044A (rs20541) using a random effects model, n indicates the total number of G alleles, N indicates the total number of G plus A alleles. 2