CV Pritinder Kaur CURRICULUM VITAE Name: Pritinder KAUR Date of birth: 14 January 1960 Citizenship: Australian Address: Epithelial Stem Cell Biology Laboratory Peter MacCallum Cancer Centre St Andrew’s Place East Melbourne Victoria 3002 Australia Phone: 61-3-9656-3714 (Office) 0408 308 271 (Mobile) 61-3-9656-1411 pritinder.kaur@petermac.org Fax: Email: Current Appointment 2000-present Senior Research Fellow, Peter MacCallum Cancer Centre Group Leader/Lab Head – Epithelial Stem Cell Biology Lab, Cancer Biology Program, Peter MacCallum Cancer Centre Senior Fellow, Dept of Biochemistry & Molecular Biology, Melbourne University 2008-2012 Senior Research Fellow, Level A, National Health & Medical Research Council of Australia 2005-present Life Fellow of the UICC Current Research Interests Molecular & cellular characterisation of human epithelial stem cells of the skin and oesophagus. Molecular & cellular characterisation of the microenvironment of human epithelial stem cells. Role of pericytes in wound healing, tumour microenvironment and tumour progression. Role of skin pericytes in epithelial stem cell and tissue renewal. Role of epithelial stem cells and their progeny in the development of ovarian carcinomas. 1 CV Pritinder Kaur Academic Qualifications B.Sc.Honours 1978-1981: Awarded by University of London; Queen Elizabeth College United Kingdom. Majoring in Cell Biology. Ph.D. 1981-1985: Awarded by University of Manchester Paterson Institute, Christie Hospital & Holt Radium Institute, Manchester, UK. Affiliated with University of Manchester. Thesis title: “Mechanisms of cell migration and differentiation in organised tissue." Defining control of epithelial cell migration that accompanies homeostatic cell renewal and differentiation in the small intestine. Supervisor : Prof Christopher S Potten Postdoctoral Training March 1985 – Aug 1988: Postdoctoral Fellow in Prof James K McDougall’s laboratory, Tumor Biology Lab, Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. Aug 1988 – July 1989: Staff Scientist Prof James K McDougall’s laboratory, Tumor Biology Lab, Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. Aug 1989 - October 1990: Staff Scientist Dr William G Carter’s laboratory, Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. Appointments Held October 1990- Dec 1994: Florey Fellow, Division of Human Immunology, Hanson Centre for Cancer Research, Adelaide, Australia. January 1995- Nov 1999: NHMRC Senior Research Officer/Associate Member, Division of Haematology, Hanson Centre for Cancer Research, Adelaide, Australia. Sabbatical fellowship - 1 August-December 2004: Visiting Scientist, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, USA. Lab of Prof Denise A Galloway. Funded by UICC, Switzerland; CASS Foundation, Melbourne; & Australian Stem Cell Centre, Melbourne. Sabbatical fellowship - 2 August-October 2010: Visiting Scientist, Albert Bonniot Institute, Universite Joseph Fourier, Grenoble, France. Lab of Prof Danielle Dhouailly. Funded by UICC, Switzerland. Awards 1982-1984 1990-1994 2004 2010 PhD scholarship, Cancer Research Campaign, UK Florey Fellowship, Royal Adelaide Hospital, Adelaide, Australia UICC ICRETT Fellowship UICC Yamagiwa-Yoshida International Cancer Study Grant 2 CV Pritinder Kaur Travel Awards 1994 1996, 1997 1998, 1999 2004 2004 EMBO Workshop travel award Anti-Cancer Council of South Australia Travel Award Medical Specialist Staff Fund Travel Award, Royal Adelaide Hospital CASS Foundation Travel Award Australian Stem Cell Centre Training Award Equipment infrastructural grants 2001 Jack Brockhoff Foundation Cryostat for frozen tissue sectioning Investigators : P Kaur, S Nilsson, P Simmons $29,000 2002 Wellcome Trust , UK Flow cytometry facility for cancer research Investigators :P Simmons, P Kaur, M Smyth, RW Johnstone, LE Purton $992,656 Research Grants Awarded a. Past support Anti-Cancer Foundation (SA) Project Grant Project title : "The role of epithelial-mesenchymal interactions in the differentiation and invasive capacity of transformed epidermal cells" Investigators : P Kaur Duration : 1992, 1993 Funds: $35,000 pa NHMRC Project Grant Principal Investigators : J Gamble (CIA) & P Kaur (CIB) Duration : 1992 - 1994. Project title : "Cell surface antigens involved in angiogenesis" Funds : $65,000 pa NHMRC Project Grant #951210 Investigators : P Kaur Duration : 1995-1997 Project Title : "Cell surface alterations during neoplastic conversion in human keratinocytes” Funds : $55,597 (supported my salary at SRO level plus consumables) NHMRC Project Grant #981881 Investigators : P Kaur (CIA), JA Rothnagel (CIB) Duration : 1998-2000 Project Title : “Characterization of human keratinocyte stem cells” Funds : $73,526 pa (supported my salary at SRO level plus consumables) NHMRC Project Grant #145654 Investigator : P Kaur (CIA), I Bertoncello (CIB) Duration : 2001-2003 Project Title : “Developmental potential of murine keratinocyte stem cells” Funds : $70,000 pa 3 CV Pritinder Kaur Sponsored Research Agreement with Organogenesis Inc., Boston, USA Investigator : P Kaur Duration : 1998, 1999 Project Title : “Characterisation of human keratinocyte stem cells to reconstitute epithelial tissue in vitro and in vivo.” Funds: US$130,000 pa NHMRC Project Grant #251535 Investigators : P Kaur Duration : 2003-2005 Project Title : “Microenvironmental regulation of tissue regenerative capacity of keratinocyte stem cells and their progeny” Funds : $124,000 pa NIH RFA Investigators : P Simmons, P Kaur, I Bertoncello, G Begley Duration : Sept 2001-2005 Project Title : “Haemopoietic potential of the epidermis” Funds : US$175,000pa Catholic Archdiocese of Sydney Adult Stem Cell Grant Investigator : P Kaur Duration : 2006 – 2007 Project Title : Improving adult skin regeneration for therapeutic purposes – the role of stem cells and the extracellular matrix protein laminin-10/11. Funds : AU$50,000pa NIH RO1 AR050013-01A2 Project Grant Investigator: P Kaur Duration : 2005-2009 Project Title: “Tissue regenerative capacity of epidermal progenitors” Funds : US$175,000 pa NHMRC Project Grant #400100 Investigators : Phillips WA, P Kaur, R Thomas Duration : 2006-2008 Project Title : Understanding Barrett’s oesophagus Funds : $92,500pa NHMRC Project Grant #455929 Investigators : Saunders NA, P Kaur Duration: 2007-2009 Project Title : Identification of clinically significant subtypes of head and neck cancer cells. Funds: $150,458 pa CASS Foundation Project Title: Can pericytes act as cancer-associated fibroblasts? Investigators : Pritinder Kaur Duration : 2009 Funds : $50,000 NHMRC #519748 Project Title : Patched gene family control of epidermal development and cancer. Duration : 2008-2010 Investigators: B Wainwright, P Kaur (CIB) 4 CV Pritinder Kaur Funds : $167,000pa ARC Project Grant : DP0878823 Project Title : The role of palmitoylation in hair follicle and stem cell biology. Duration : 2008-2010 Investigators : I Smyth, P Kaur, I J Jackson Funds : $81,000 pa Cancer Council of Victoria #807184 Project Title : Biological characterisation of pericytes in cancer and as mesenchymal stem cells. Duration : 2009; 2010 Investigators : P Kaur Funds : $ 100,000 pa b. Current Research Grant Support NHMRC Senior Research Fellowship Salary Support for Pritinder Kaur Duration : 2008-2012 Funds : $107,500 pa Alfred Burns Unit Collaborative Research Agreement Project Title : Improving adult keratinocyte growth for clinical use in burns patients Duration : 2009/10, 2010/11 Investigators : P Kaur Funds : $99,092pa Sponsored Research Agreement with L’Oreal, Paris, France Project Title : The role of pericytes in keratinocyte aging Duration : 2011-2013 Investigators : P Kaur Funds : $160,000 pa NHMRC #1025874 Project Title : The microenvironmental niche in cancer progression Duration : 2012-2014 Investigators : P Kaur & H Schlueter Funds : $181,000 pa 5 CV Pritinder Kaur PUBLICATIONS: Refereed Journal articles (JIF=Journal Impact Factors from 2009): Citations updated December 2010. *denotes ten most significant publications PUBLICATIONS: Refereed Journal articles (JIF=Journal Impact Factors from 2009): Citations updated December 2010. *denotes ten most significant publications 1. Kaur P and Potten CS. Circadian variation in migration velocity in small intestinal epithelium. Cell Tissue Kinet. 19:591-599, 1986a. (30 citations; JIF 4.492) 2. Kaur P and Potten CS. Cell migration velocities in the crypts of the small intestine after cytotoxic insult are not dependent on mitotic activity. Cell Tissue Kinet. 19:601-610, 1986b. (56 citations; JIF 4.492) 3. Kaur P and Potten CS. Effects of puromycin, cycloheximide and noradrenaline on cell migration within the crypts and on the villi of the small intestine. Cell Tissue Kinet. 19:611-625, 1986c. (19 citations; JIF 4.492) 4. Loeffler M, Stein R, Wichmann HE, Potten CS, Kaur P, and Chwalinski S. Intestinal cell proliferation. I. A comprehensive model of steady state proliferation in the crypt. Cell Tissue Kinet. 19:627-645, 1986. (56 citations; JIF 4.492) 5. *Kaur P and McDougall JK. Characterisation of primary human keratinocytes transformed by human papillomavirus type 18. J Virology 62:1917-1924, 1988. (190 citations; JIF 5.150) 6. Kaur P, McDougall JK and Cone R. Immortalisation of primary human epithelial cells by cloned cervical carcinoma DNA containing human papillomavirus 16 E6/E7 ORFs. J Gen Virol 70:1261-1266, 1989. (89 citations; JIF 3.260) 7. Kaur P and McDougall JK. HPV-18 immortalisation of human keratinocytes. 173:302-310, 1989. (80 citations; JIF 3.042) 8. Smith PP, Bryant EM, Kaur P and McDougall JK. Cytogenetic analysis of eight human papillomavirus immortalized human keratinocyte cell lines. Int J Cancer 44:1124-1131, 1989. (48 citations ; JIF 4.722) 9. *Carter WG, Wayner EA, Bouchard TS and Kaur P. The role of integrins 21 and 1 in cell-cell and cell-substrate adhesion of human epidermal cells. J Cell Biol 110:1387-1404, 1990. (576 citations; JIF 9.575) 10. *Carter WG, Kaur P, Gil SG, Gahr PJ and Wayner EA. Distinct functions for integrins 31 in focal adhesions and 64/Bullous Pemphigoid antigen in a new stable anchoring contact (SAC) of keratinocytes: Relation to hemidesmosomes. J Cell Biol 111:3141-3154, 1990. (397 citations; JIF 9.575) 11. *Hurlin PJ, Kaur P, Smith PP, Perez-Reyes N, Blanton RA and McDougall JK. Progression of human papillomavirus type 18-immortalized human keratinocytes to a malignant phenotype. Proc Natl Acad Sci USA 88:570-574, 1991. (168 citations; JIF 9.432) Virology 6 CV Pritinder Kaur 12. *Kaur P and Carter WG. Integrin expression and differentiation in transformed human epidermal cells is regulated by fibroblasts. Journal Cell Science 103:755-763, 1992. (25 citations; JIF 6.144) 13. Gamble JR, Matthias LJ, Meyer G, Kaur P, Russ G, Faull R, Berndt M and Vadas MA. Regulation of in vitro capillary tube formation by anti-integrin antibodies. J Cell Biol 121:931934, 1993. (155 citations; JIF 9.575) 14. Kaur P, Pascoe R, Halbert CL, Smith W and Vadas MA. Establishment of a human umbilical vein endothelial cell line with novel functional capabilities. Endothelium 2: 113-125, 1994. (N/A; JIF 1.649) 15. Kaur P, Paton S, Furze J, Wrin J, Olsen S, Danks J and Scurry J. Identification of a cell surface protein with a role in stimulating human keratinocyte proliferation, expressed during development and carcinogenesis. J. Invest. Dermatol. 109 : 194-9, 1997. (7 citations ; JIF 5.543) 16. *Li A, Simmons PJ & Kaur P. Identification and isolation of candidate human keratinocyte stem cells based on cell surface phenotype. PNAS-USA 95 : 3902-3907, 1998. (240 citations; JIF 9.432) 17. Kaur P & Li A. Characterisation of the adhesive properties of human keratinocytes : an analysis of stem, transit amplifying and post-mitotic differentiating cells. Journal of Investigative Dermatology, 114:413-20, 2000. (88 citations; JIF 5.543) 18. Dicker AJ, Dahler AL, Khanna KK, Kaur P, Li A, Strutton G, Frazer IH and Saunders NA. Functional characterisation of cultured cells derived from an intraepidermal carcinoma of the skin (IEC-1). Exp. Cell Res., 258:352-360, 2000. (13 citations; JIF 3.589) 19. *Tani H, Morris RJ & Kaur P. Enrichment for murine keratinocyte stem cells based on cell surface phenotype. PNAS-USA, 97 10960-10965, 2000. (199 citations; JIF 9.432) 20. Pouliot N, Saunders NA and Kaur P. 2002. Laminin-10/11:an alternative adhesive ligand for epidermal keratinocytes with a functional role in promoting proliferation and migration. Exp. Dermatol. 11: 387-397. (31 citations; JIF 3.239) 21. *Li A, Pouliot N, Redvers R and Kaur P. 2004. Extensive tissue regenerative capacity of neonatal human keratinocyte stem cells and their progeny. J. Clin.Invest. 113:390-400. (83citations; JIF 15.387) 22. Gugasyan R, Voss A, Varigos G, Thomas T, Grumont RJ, Kaur P, Grigoriadis G, Gerondakis S. 2004. The Transcription Factors c-rel and RelA Control Epidermal Development and Homeostasis in Embryonic and Adult Skin via Distinct Mechanisms. Mol Cell Biol. 24:5733-45. (38 citations; JIF 6.057) 23. Adolphe C, Narang M, Ellis T, Wicking C, Kaur P and Wainwright B. 2004. An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis. Development, 131: 5009-5017. (52 citations; JIF 7.194) 24. Webb A, Li A and Kaur P. 2004. Location and phenotype of adult keratinocyte stem cells of the skin. Differentiation. 72: 387-95. (77 citations; JIF 3.311) 7 CV Pritinder Kaur 25. Edmondson SR, Thumiger SP, Kaur P, Loh B, Koelmeyer R, Li A, Silha JV, Murphy LJ, Wraight CJ, Werther GA. 2005. Insulin-like growth factor binding protein-3 (IGFBP-3) localizes to and modulates proliferative epidermal keratinocytes in vivo. Br J Dermatol. 152: 225-230. (18 citations; JIF 4.260) 26. Pouliot N, Redvers RP, Ellis S, Saunders NA and Kaur P. 2005. Optimisation of a transplant model to assess skin reconstitution from stem cell-enriched primary human keratinocyte populations. Exptl Dermatol, 14: 60-69. (14citations; JIF 3.239) 27. Ting SB, Caddy J, Hislop N, Wilanowski T, Auden A, Zhao LL, Ellis S, Kaur P, Uchida Y, Holleran WM, Elias PM, Cunningham JM, Jane SM. 2005. A homolog of Drosophila grainy head is essential for epidermal integrity in mice. Science. 308:411-413. (66 citations; JIF 29.747) 28. *Redvers RP, Li A, Kaur P. 2006. The side population in adult murine epidermis exhibits phenotypic and functional characteristics of keratinocyte stem cells. PNAS-USA, 103(35):13168-73 (35 citations; JIF 9.432) 29. Croagh D, Phillips WA, Redvers R, Thomas RJ, Kaur P. 2007. Identification of candidate murine esophageal stem cells using a combination of cell kinetic studies and cell surface markers. Stem Cells 25 (2): 313-318 (19 citations; JIF 7.747). 30. Gangatirkar P, Paquet-Fifield S, Li A, Rossi R, Kaur P. 2007. Isolation of primary keratinocytes from neonatal foreskin and organotypic culture. Nature Protocols. 2(1):178-86 (JIF 6.335) 31. Croagh, D, Tikoo A, Cheng S, Nandurkar S, Thomas RJ, Kaur P & Phillips WA. 2008. Reconstitution of stratified murine and human oesophageal epithelia in an in vivo transplant culture system. Scan J Gastroenterol. 43(10):1158-68. (4 citations; JIF 2.084). 32. Endo-Munoz L, Dahler A, Teakle N, Rickwood D, Hazar-Rethinam M, Abdul-Jabbar I, Sommerville S, Dickinson I, Kaur P, Paquet-Fifield S, Saunders NA. 2009. E2F7 can regulate proliferation, differentiation and apoptosis in human keratinocytes: implications for cutaneous squamous cell carcinoma formation. Cancer Res., 69: 1800-1808. (6 citations; JIF 7.543). 33. Paquet-Fifield S, Schlüter H, Li A, Aitken T, Gangatirkar P, Blashki D, Koelmeyer R, Pouliot N, Palatsides M, Ellis S, Brouard N, Zannettino A, Saunders N, Thompson N, Li J and Kaur P. 2009. A role for pericytes as microenvironmental regulators of human skin tissue regeneration. J Clin Invest. 119 (9):2795-806. (23 citations; JIF 15.387). 34. Schlüter H, Paquet-Fifield S, Gangatirkar P and Kaur P. 2011. Functional characterisation of quiescent keratinocyte stem cells and their progeny reveals a hierarchical organisation in human skin epidermis. Stem Cells. 29(8):1256-68. Accepted online 14 Jun 2011 DOI:10.1002/stem.675. (JIF 7.871). Book Chapters/Methods 35. McDougall JK, Beckmann AM, Kaur P, and Galloway DA. DNA viruses in anogenital cancer. Medical Virology VI pp.261-283. Eds. LM de la Maza and EM Peterson. Elsevier, 1987. 36. Carter WG, Symington BE and Kaur P. Cell adhesion and the basement membrane in early epidermal morphogenesis. In: 'Epithelial Organization in Development'. Ed. T.P. Fleming, Chapman & Hall (London), 1992, pp. 299-327. 8 CV Pritinder Kaur 37. Kaur P. Immortalization of human keratinocytes with human papilloma virus. Cell & Tissue Culture: Lab Procedures 261:1-7, 1994. 38. Kaur P . and Halbert CL. Immortalization of human keratinocytes with human papilloma virus DNA. Methods in Cell Science 17: 117-123, 1995. 39. Upjohn E, Varigos G & Kaur P. 2004. Burns and leg ulcers. In "Handbook of Embryonic Stem Cells". Edited by Doug Melton, James Thomson, John Gearhart, Brigid Hogan, Ron McKay, Roger Pedersen, Mike West and Robert Lanza. Academic Press, pp731-736. 40. Li A & Kaur P. 2005. "FACS enrichment of keratinocyte stem cells" In “Epidermal Protocols”. p87-96. Edited by Kursad Turksen. Humana Press. 41. Redvers RP & Kaur P. 2005. "A simple protocol for propagating adult murine keratinocytes in culture" In “Epidermal Protocols”. pp15-22. Edited by Kursad Turksen. Humana Press. 42. Upjohn E, Varigos G & Kaur P. 2006. “Leg ulcers and Burns” in “Essentials of Stem Cell Biology”, p419-424. Edited by Robert Lanza, Elsevier Inc. 43. Redvers R and Kaur P. 2006. “Stem cell populations of the skin” in “Tissue Stem Cells : Biology & Applications” Edited by CS Potten, R Clarke, A Renehan and J Wilson, Dekker. pp 117-148. 44. Paquet-Fifield S, Redvers RP, Pouliot N and Kaur P. 2009. A transplant model for human epidermal skin regeneration. In Methods in Molecular Biology series. In press; and Springer's Protocols On-Line [http://www.springerprotocols.com/]. 45. Upjohn E, Varigos G & Kaur P. 2009. Burns and leg ulcers. In "Essentials of Stem Cell Biology" 2nd Edition. Edited by Robert Lanza, John Gearhart, Brigid Hogan, Douglas Melton, Roger Pedersen, E.Donnall Thomas, James Thomson, and Ian Wilmut. Academic Press, pp523542. 46. Schluter H, Upjohn E, Varigos G & Kaur P. Burns and leg ulcers. In "Essentials of Stem Cell Biology". Edited by Robert Lanza, John Gearhart, Brigid Hogan, Douglas Melton, Roger Pedersen, E.Donnall Thomas, James Thomson, and Ian Wilmut. Academic Press. Submitted June 2011. Invited Commentaries/Reviews 47. Cotsarelis G, Kaur P, Dhouailly D, Hengge U & Bickenbach J. Epithelial stem cells in the skin : definition, markers, functions, and localization. Experimental Dermatology, 8:80-8, 1999. (97 citations; JIF 3.239) 48. Hengge UR, Taichman LB, Kaur P, Rogers G, Jensen TG, Goldsmith LA, Rees JL & Christiano AM. How realistic is cutaneous gene therapy? Experimental Dermatology, 8:419-431, 1999. (13 citations; JIF 3.239) 49. Kaur, P & Wood, F. 2005. Stem cells of the skin. Australian Biochemist 36: 15-18 . 50. Webb A & Kaur P. 2006. “Epidermal Stem Cells” Frontiers in Bioscience 11:1031-1041. (3 citations; JIF 3.736) 9 CV Pritinder Kaur 51. *Kaur P. 2006. Interfollicular Epidermal Stem Cells : Identification, Challenges, Potential. J Invest Dermatol 126(7):1450-8. (47 citations; JIF 5.543) 52. Kaur P. 2004. Women in Cell Science : An interview with Fiona Watt. J Cell Sci. 117: 28692870. (JIF 6.144) 53. Daniel Croagh D, Robert J.S. Thomas RJS, Phillips WA & Kaur P. 2008. Esophageal stem cells – a review of their identification and characterization. Stem Cell Reviews. 4:261-8. Published online Aug 5 2008. DOI 10.1007/s12015-008-9031-3. (JIF 5.083) 54. Schlueter H & Kaur P. 2009. Making skin from human embryonic stem cells. Lancet 374 (9703) : 1725-6. (1 citation; JIF 30.758) 55. Kaur P & Potten CS. 2011. Biology of interfollicular keratinocytes : sensationalism versus reality check. Exp Derm. 20(9):697-702. Accepted online 25 Jun 2011 DOI: 10.1111/j.16000625.2011.01338.x (JIF 4.159) 56. Clemons N, Phillips W and Kaur P. Oesophageal stem cells : a review. Central European Journal of Biology Mini Review. Submitted June 2011. 57. Schlueter H & Kaur P. Distinguishing human interfollicular epidermal stem cells from committed progenitors using a limit dilution transplant assay. Edited by Kursad Turksen. Submitted Dec 2011. Invited Commentaries/Reviews 58. Cotsarelis G, Kaur P, Dhouailly D, Hengge U & Bickenbach J. Epithelial stem cells in the skin : definition, markers, functions, and localization. Experimental Dermatology, 8:80-8, 1999. (97 citations; JIF 3.239) 59. Hengge UR, Taichman LB, Kaur P, Rogers G, Jensen TG, Goldsmith LA, Rees JL & Christiano AM. How realistic is cutaneous gene therapy? Experimental Dermatology, 8:419-431, 1999. (13 citations; JIF 3.239) 60. Kaur, P & Wood, F. 2005. Stem cells of the skin. Australian Biochemist 36: 15-18 . 61. Webb A & Kaur P. 2006. “Epidermal Stem Cells” Frontiers in Bioscience 11:1031-1041. (3 citations; JIF 3.736) 62. *Kaur P. 2006. Interfollicular Epidermal Stem Cells : Identification, Challenges, Potential. J Invest Dermatol 126(7):1450-8. (47 citations; JIF 5.543) 63. Kaur P. 2004. Women in Cell Science : An interview with Fiona Watt. J Cell Sci. 117: 28692870. (JIF 6.144) 64. Daniel Croagh D, Robert J.S. Thomas RJS, Phillips WA & Kaur P. 2008. Esophageal stem cells – a review of their identification and characterization. Stem Cell Reviews. 4:261-8. Published online Aug 5 2008. DOI 10.1007/s12015-008-9031-3. (JIF 5.083) 65. Schlueter H & Kaur P. 2009. Making skin from human embryonic stem cells. Lancet 374 (9703) : 1725-6. (1 citation; JIF 30.758) 10 CV Pritinder Kaur 66. Kaur P & Potten CS. 2011. Biology of interfollicular keratinocytes : sensationalism versus reality check. Exp Derm. 20(9):697-702. Accepted online 25 Jun 2011 DOI: 10.1111/j.16000625.2011.01338.x (JIF 4.159) 67. Clemons N, Phillips W and Kaur P. Oesophageal stem cells : a review. Central European Journal of Biology Mini Review. Submitted June 2011. 68. Schlueter H & Kaur P. Distinguishing human interfollicular epidermal stem cells from committed progenitors using a limit dilution transplant assay. Edited by Kursad Turksen. Submitted Dec 2011. Conference Papers 69. Kaur P and McDougall JK. Transformation of mouse cells by HPV6b DNA and HPV-18 DNA. Cancer Cells 5:249-252. Eds. BM Steinberg, JL Brandsma and LB Taichman. Cold Spring Harbor Laboratory. CSF, NY, 1987. 70. Kaur P, Li A, Redvers R and Bertoncello I. 2004. Keratinocyte stem cell assays : an evolving science. J Invest Dermatol. Symposium Proceedings 9: 238-247. Patents 71. Kaur P & Simmons PJ. 2000. Isolation of human keratinocyte stem cells. Patent #0022845. Awarded in the USA, UK and Australia. Conference Presentations : Selected Speaker 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. October 1984. Cell & Tissue Kinetics Conference, Munich, West Germany. "Mechanisms of intestinal epithelial migration". November 1984. International Radiation Biology Conference, Dublin, Ireland. "The effects of radiation on intestinal epithelial migration in mice". June 1987. Sixth International Papillomavirus Workshop, Georgetown University, Washington DC, USA. "Immortalization of human keratinocytes with HPV-18". August 1987. Gordon Conference 'Epithelial Keratinization & Differentiation', Tilton, NH, USA. "Transformation studies with cloned human papillomavirus DNA in primary human epithelial cells". May 1988. Seventh International Papillomavirus Workshop, Sophia Antipolis, France. "Transformation of human epithelial cells by HPV-18". May 1991. Australian Medical research Society Meeting, Adelaide, Australia. “Integrin expression in HPV transformed human keratinocytes is regulated by their mesenchymal environment”. February 1992. Fourth Lorne Cancer Conference, Lorne, Australia. "Fibroblast mediated regulation of integrin expression and differentiation in transformed human epidermal cells". February, 1994. Sixth Lorne Cancer Conference, Lorne, Australia. "Alterations in human epidermal cell surface molecules associated with progression in carcinogenesis". November 1996. Fifth Hanson Symposium, Adelaide, Australia. “Identification of a cell surface protein expressed during development and carcinogenesis, with a functional role in stimulating proliferation in human keratinocytes.” December 1996. “Isolation of human keratinocyte stem cells.” 15th International Papillomavirus Workshop, Gold Coast, Australia. July 1997. Gordon Conference on Epithelial Differentiation and Keratinization, Tilton, USA. “Identification of candidate human keratinocyte stem cells.” May 1998. Satellite Symposium on Keratinisation and its Disorders - a molecular perspective, Kloster-Walberberg, Germany. “Adhesive properties of basal epidermal human 11 CV Pritinder Kaur 13. 14. 15. 16. 21. 22. 23. 24. 25. keratinocytes : An analysis of the stem, transit amplifying and post-mitotic differentiated compartments.” July 1999. Gordon Conference on “Epithelial Keratinisation and Differentiation”, Tilton., USA. “Enrichment for murine epidermal label-retaining cells based on cell surface markers using a fluorescence-activated cell sorting (FACS) approach.” October 1999. EMBO Workshop “Stem Cells, Growth Factors & Cancer”, Torino, Italy. “Enrichment for murine epidermal label-retaining cells based on cell surface markers using a fluorescence-activated cell sorting (FACS) approach.” July 2000. 18th International Papillomavirus Conference, Barcelona, Spain. “Biological characterization of human keratinocyte stem cells”. Feb 2001. Lorne Cancer Conference, Lorne, Australia. “In vitro tissue regenerative capacity of keratinocyte stem cells and their progeny is determined by their mesenchymal microenvironment”. May 2002. Society of Investigative Dermatology, Los Angeles, USA. “Laminin-10/11 restores the intrinsically poor regenerative capacity of differentiating keratinocytes”. May 2005. Gordon Research Conference on “Epithelial Keratinization and Differentiation”, Barga, Italy. Feb 2007. 19th Lorne Cancer Conference. “Regulation of skin tissue renewal via epidermal stem cells and their microenvironment.” Lorne, Australia. March 2007. Hunter Cell Biology Meeting, Pokolbin, New South Wales, Australia. May 2007. 4th Australasian Society of Dermatological Research Scientific Meeting Adelaide. Conference Presentations : Invited Speaker 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. September 1998. Australian and New Zealand Developmental Biology Society Meeting, Adelaide, Australia.“Characterisation of human keratinocyte stem cells.” September 2001. Japanese Society of Investigative Dermatology Stem Cell Workshop, Matsuyama, Japan. “Human keratinocyte stem cells: identification, isolation and biological characterisation”. July 2002. “Workshop on Skin Stem Cells”, World Congress of Dermatology, Paris. “Micro environmental regulation of the regenerative potential of keratinocyte stem cells and their progeny”. November 2002. Queensland University of Technology, Bioscience for the Real World, 2002: Frontiers in Tissue Engineering, Brisbane, Australia. “Microenvironmental regulation of the tissue regenerative capacity of keratinocyte stem cells and their progeny”. November 2002. “International conference On Radiation damage and its modification”, Delhi, India. (Invitation Declined). November 2002. Australian Hair and Wool Research Society Meeting, Melbourne, Australia. “Microenvironmental regulation of the tissue regenerative capacity of keratinocyte stem cells and their progeny”. June 2003. 52nd Montagna Symposium “Stem Cells in Skin”, Snowmass Village, USA. “Establishment of a transplant model to assess keratinocyte stem cell potency”. July 2003. Workshop on “Stem Cells and stem cell plasticity”, Gordon Conference on Epithelial Keratinization and Differentiation, Tilton, USA. “Stem cell activity as a function of microenvironment”. October 2003. First National Stem Cell Centre Conference “Stem cells and Tissue Repair” Melbourne, Victoria, Australia. “Tissue regeneration from skin stem cells and their progeny” Plenary Speaker. October 2003. International Society for Interferon and Cytokine Research Annual meeting. Cairns, Queensland, Australia. “Tissue regeneration of keratinocyte stem cells and their progeny”. January 2004. Summer Conference on “Molecular Mechanisms of Development” Perth, Western Australia, Australia. 12 CV Pritinder Kaur 12. 13. 14. 15. 16. 17. 18. 19. February 2004. Tissue regenerative capacity is not restricted to keratinocyte stem cells. Lorne Cancer Conference, Lorne, Australia. May 2004. Inaugural Meeting of the Australian Society for Dermatological Research, Sydney, Australia. Plenary Speaker. Sept 2004. Australia & New Zealand Matrix Biology Society meeting, Rottnest Island, Western Australia. Sponsored by Clinical Cell Culture (Fiona Wood), Perth. Feb 2005. Timberline Symposium on “Keratinocyte Stem cells : tissue regeneration, wound healing and environmental responses”, Mt Hood, Oregon, USA. Keynote opening address. March 2005. Walter Cottman Mini-Symposium on “Telomeres, Cancer & Stem Cells”. Monash University at Alfred Hospital, Melbourne, Australia. Dec 2005. Indian Academy of Science Symposium on “Stem Cell Research: Technical, Ethical and Social Issues” Centre for Cellular & Molecular Biology, Hyderabad, India. June 2006. 13th International Congress on Oral Pathology and Medicine, Brisbane, Australia. Plenary Speaker. Oct 2006. XVII Annual Meeting of the Indian Society of Organ Transplantation, Ahmedabad, India. Declined. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. Oct 2006. L’Oréal International Symposium on “The Science and Technology of Skin.” Shanghaï, China. Meeting cancelled. Nov 2006. Australian Health and Medical Research Congress. Cancer Stem Cells Session. Melbourne, Australia. 19th July 2007. Keynote speaker : Sydney XII STEAM (Sydney Tissue Engineering and Matrix Group) meeting. 19th July 2007. Sponsored by Becton Dickinson. Oct 2007. 21st World Congress of Dermatology. Stem Cell Session. Buenos Aires, Argentina. Feb 2008. Timberline Symposium on Epithelial Cell Biology “3D Tissue Biology: Human Stem Cells, Cancer & the Microenvironment”, Mount Hood, Oregon, USA. 9th-12th February 2008. Sponsored by Invitrogen. Feb 2008. “Model Organisms and Stem Cell in Development, Regeneration and Disease” National Centre for Biological Sciences, TIFR, Bangalore, India. 23rd-25th February 2008. Sponsored by NCBS. Nov 2008. Australian Health and Medical Research Congress. “Stem Cells Session” Brisbane, Australia. March 2009. Wellcome Trust Conference and retreat on “Perspectives in Stem Cell Proteomics”, Wellcome Trust Conference Centre, Cambridge, UK. December 2009. 34th Japanese Society for Investigative Dermatology Annual Scientific Meeting, Oceania Stem Cell Forum, Fukuoka, Japan. March 2010. 10th Anniversary Hunter Cellular Biology Meeting, Hunter Valley, New South Wales. March 2010. 2nd Australasian Wound and Tissue Repair Society Meeting: Crossing the Boundaries. Perth, Western Australia. June 2010. Keynote speaker. 7th Australasian Society of Dermatological Research Scientific Meeting, Cairns, Australia. June 2010. Keynote speaker. “Cell-based regenerative medicine from human skinderived progenitors” Conference, Luebeck, Germany. Sept 2011. Invited Speaker. Stem Cell Workshop, Institute for Stem Cell Biology & Regenerative Medicine, Bangalore, India. June 2011. Invited Speaker. 2nd Luebeck Regenerative Medicine Symposium. Frontiers in Skin Wound Healing, Luebeck, Germany. Invited Discussant 1. May 1998. Round table Discussion on “New therapeutical concepts for the treatment of disorders of cornification” at Satellite Symposium on Keratinisation and its Disorders - a molecular perspective, Kloster-Walberberg, Germany. 13 CV Pritinder Kaur 2. 3. Dec 2005. Panel Discussion on “Ethical Issues in Stem Cell Research”, Indian Academy of Science Symposium on “Stem Cell Research: Technical, Ethical and Social Issues” Centre for Cellular & Molecular Biology, Hyderabad, India. July 2007. Gordon Conference on “Epithelial Differentiation & Keratinization”. Discussion Leader on “Skin Stem Cells”, Bryant University, Rhode Island, USA. Session chair 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. November 2001. Chair : “Stem Cell” Sessions at the 4th Peter MacCallum Cancer Institute Symposium on “Molecular & Cell Biology of Cancer”, Melbourne, Australia. July 2003. Co-chair of the “Stem Cells and Plasticity” Workshop at Gordon Conference on “Epithelial Keratinization and Differentiation” Tilton, New Hampshire, USA. October 2003. Chair “Tissue Engineering” session of the First National Stem Cell Centre Conference “Stem cells and Tissue Repair” Melbourne, Australia November 2003. Chair of “Skin Cancer and HPV” session of the 5th Peter MacCallum Cancer Centre Symposium “Molecular & Cell Biology of Cancer” Melbourne, Australia. May 2005. Chair of scientific session, 2nd Annual Scientific Meeting of the Australasian Society of Dermatological Research, Perth, Australia. November 2005. Chair Plenary Session 4 and Co-chair of Stem Cell Workshop 1, 6th Peter MacCallum Cancer Symposium on “Molecular & Cell Biology of Cancer”, Melbourne, Australia. May 2006. Chair “Polarity” Session, Australasian Society for Dermatological Research 3rd Annual Scientific Meeting, Melbourne. Sept 2006. Chair “Stem cells & Cancer” session of the 2nd Straddie Boden Conference on Cutaneous Biology, North Stradbroke Island, Australia. May 2007. Chair “Stem cells & Tissue Engineering” session of the 4th ASDR Annual Scientific Meeting, Adelaide, Australia. February 2008. Chair, “The Stem cell Niche” Session. Timberline Symposium on Epithelial Cell Biology, Mount Hood, Oregon, USA. May 2008. Chair “Skin Diseases” session ASDR 5th Annual Scientific Meeting, Sydney, Australia. Oct 2008. Chair “Young Investigator” Session, 1st Peter MacCallum Wilson’s Prom Workshop “Cancer Epigenetics” Feb 2009. Co-Chair “Proteins & Stem Cells” Session, 34th Annual Lorne Conference on Protein Structure and Function, Lorne, Australia. June 2010. Chair, 6th World Congress of Hair Research Societies Meeting. “Stem Cell, Stem Cell Niches and Cicatricial Alopecia" Session, Cairns, Australia. May 2011. Chair, ASDR Annual Scientific Meeting, Perth, Australia. October 2011. Co-Chair, Australasian Society for Stem Cell Research, 4th Annual Meeting, Leura, Blue Mountains, NSW, Australia. Invited Seminars (Institutes/Universities/Industry etc): 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. Dec 1985 Aug 1990 Oct 1993 Oct 1994 Nov 1994 Jul 1995 Feb 1996 Jul 1996 Apr 1997 May 1997 Jun 1997 University of Washington, Seattle, USA..0 University of Washington, Seattle USA Biochemistry Dept, University of Adelaide. Medical School, University of Adelaide. Princess Alexandra Hospital, Brisbane. Systemix, Palo Alto, USA CSIRO Division of Biomolecular Engineering, Sydney Peter MacCallum Cancer Institute, Melbourne. Waite Institute, Adelaide Dept of Genetics, University of Adelaide. Princess Alexandra Hospital, Lions Immunology Unit, Brisbane 14 CV Pritinder Kaur 12. 13. 14. Jul 1997 Jul 1997 Aug 1997 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. Sep 1997 May 1998 Jun 1998 Jun 1998 Mar 1999 Apr 1999 Apr 1999 Apr 1999 Jul 1999 Aug 1999 Sep 1999 Jul 2000 Jul 2000 Apr 2001 Jun 2002 Aug 2002 Sep 2002 Mar 2003 Mar 2003 Sep 2003 Mar 2004 Oct 2004 Sep 2005 38. 39. 40. 41. 42. Dec 2005 Dec 2005 Aug 2006 Sep 2007 Oct 2007 43. Oct 2009 44. 45. 46. 47. 48. 49. 50. Dec 2009 Sep 2010 Sep 2010 Oct 2010 Oct 2010 Mar 2011 Sept 2011 Fred Hutchinson Cancer Research Center, Seattle, USA. Organogenesis Inc., Boston, USA. Lab of Cellular Carcinogenesis, National Instititutes of Health, Bethesda, USA. German Cancer Research Center, Heidelberg, Germany. Lausanne University Hospital, Lausanne, Switzerland. Stony Brook Health Sciences Center, NY, USA. Peter MacCallum Cancer Institute, Melbourne. Adelaide Developmental Biology Group, University of Adelaide. Organogenesis Inc, Boston, USA. Millenium Pharmaceuticals Inc., Boston, USA. Lankenau Medical Research Center, Philadelphia, USA Fred Hutchinson Cancer Research Center, Seattle, USA. Dept of Microbiology & Immunology, University of Adelaide. Institute of Medical & Veterinary Science, Adelaide. Baylor Medical College, Houston, USA. Royal London Hospital, London, UK. Columbia University, New York, USA. Monash Medical Centre, Melbourne Deakin University, Melbourne. Children’s Health Research Institute, Adelaide. Royal Melbourne Hospital, Melbourne. IMB, University of Queensland, Brisbane. Bernard O’Brien Institute of Microsurgery Ludwig Institute for Cancer Research, Melbourne. Cancer Biology Program, Fred Hutchinson Cancer Centre Centre for Immunology & Cancer Res, Princess Alexandra Hospital, Br Brisbane. Madurai Kamaraj University, Madurai, India. National Centre of Biological Sciences, Bangalore, India. Children’s Medical Research Institute, Sydney. Biopolis, Singapore 20th Sept 2007. Sponsored by Biopolis. Queensland University of Technology, Institute of Health & Biomedical Innovation, Brisbane. Monash Immunology and Stem Cell Laboratories, Monash University, Melbourne Institut fur Biochemistry, Aachen University, Germany. Albert Bonniot Institute, Universite Joseph Fourier, Grenoble, France. University of Luebeck, Luebeck, Germany. German Cancer Research Center, Heidelberg, Germany. L’Oreal Life Sciences Research Laboratories, Paris, France. Centre for Stem Cell Research, University of Adelaide, Adelaide. Ludwig Institute for Cancer Research, Parkville, Melbourne. Grant/Fellowship reviewer for : National Health & Medical Research Council, Australia Queensland Cancer Fund. Leo & Jenny Leukemia & Cancer Foundation Medical Research Council, UK Australian Stem Cell Centre Cancer Research UK Swiss National Science Foundation Research Grants Council of Hong Kong 15 CV Pritinder Kaur Australian College of Dermatologists Medical Research Council, UK. National Medical Research Council of Singapore Grant Review panel Member: Australian Stem Cell Centre (2004-2006) NIH RO3 Special Emphasis Review panel 2005, 2007, 2008 (declined) NHMRC Grant Review Panel 2009 GrP1g Cell Biology NHMRC Grant Review Panel 2010 (declined due to timing conflict with sabbatical leave) NHMRC Grant Review Panel 2011 GRP2a Cell Biology & Regenerative Medicine Australian College of Dermatology 2007-present. Society Membership 1996-1999: 1998: 2000-present: 2000-present: 2001-present: 2004–present: 2004-present: 2007-present: 2011-present : European Society of Dermatological Research. The American Society of Gene Therapy. Society of Investigative Dermatology (USA). Australian Society for Medical Research. Australia & New Zealand Cell & Developmental Biology Society. International Society for Stem Cell Research (USA) Australian Society for Dermatological Research. Australasian Wound and Tissue Repair Society Australian Society for Stem Cell Research Executive Positions 1. 2. 3. 4. 5. 6. 7. 8. 2004-present. Inaugural Board Member (and Treasurer 2004-2007), Australian Society for Dermatological Research (ASDR). The ASDR formed in 2004 to promote the research activities of all skin biologists with basic science and clinical disease. 2004-2006. Member of the Scientific Management Advisory Committee, Australian Stem Cell Centre. 2004-present. Editorial Board Member for ‘Stem Cells”, The International Journal of Cell Differentiation and Proliferation. Oct 2006; Sept 2008. Member, Scientific Advisory Board. Scientific Review of Research Programs at Children’s Health Research Institute, Adelaide. Reinvited to serve on SAC for Sept 2010 – Declined due to timing of sabbatical leave in France. Jan 2007-present. Member, Scientific Research Committee of the Australian College of Dermatologists. April 2007-2010. Board Member, Australasian Wound and Tissue Repair Society. Jan 2008-present. Editorial Board Member for “Stem Cell Reviews”. June 2010. President Elect of The Australian Society for Dermatological Research Conference organisation 1. November 2001. Fourth Peter Mac Symposium “Molecular & Cell Biology of Cancer.” Organising Committee Member and Chair : Stem Cell Biology Sessions I and II. Role : Provide input to the scientific Program, invite and liase with overseas and national speakers, and assist with advertising and promoting the Conference. 2. April 2002. First Boden Research Conference on “Developmental Cutaneous Biology”, Stradbroke Island, Australia. This meeting was co-organised with Dr Joe Rothnagel, University of Queensland. Role : Convenor and responsibilities included fund raising (through grant applications and other avenues), inviting all overseas and national speakers, 16 CV Pritinder Kaur selecting Abstracts for oral presentation, managing the Conference budget, preparing Conference booklets, arranging local transportation and promoting the Conference. 3. June 2003. Program Committee Member 52nd Montagna Symposium “Stem Cells in Skin”, Snowmass Village, USA. Duties: Providing input into developing the scientific content of this meeting and inviting international speakers in the US and Europe. 4. July 2003. Moderator/Organiser, Workshop on “Stem Cells and stem cell plasticity”, Gordon Conference on Epithelial Keratinization and Differentiation, Tilton, USA. Duties : Screen all submitted Abstracts (150) for oral presentation at the Stem Cell Workshop and promote discussion as co-chair of the workshop, highlighting current keratinocyte stem cell work. 5. May 2006. Australasian Society for Dermatological Research Annual Scientific Meeting, Melbourne. Local Chairperson/Scientific Program Committee Member. 6. September 2006. Second Boden Conference on “Epithelial Stem Cells & Cutaneous Regeneration” Stradbroke Island, Australia. Meeting co-organiser. 7. June 2007. Poster judge for Australian Stem Cell Centre at the International Society for Stem Cell Research Annual Meeting, Cairns, Australia. 8. Oct 2008 : Co-ordinator, Peter MacCallum Wilson’s Prom Workshop (to replace Peter Mac Symposium). Role : Took up initiative for organising Gordon Conference - style meeting; obtained internal and external funding to support international and national scientists for inaugural meeting held 14th-16th October 2008 on “Cancer Epigenetics”; Member, Scientific Program Committee. 9. March 2010. 2nd Australasian Wound and Tissue Repair Society Meeting: Crossing the Boundaries. Perth, Western Australia. Judge for prizes awarded for best talks from students and postdoctoral fellows. 10. May 2013. Joint ASDR/ASPCR scientific meeting. Co-organiser. Teaching Activities A. Undergraduate teaching: May 1997: Guest Lecturer at University of Adelaide, Department of Genetics “Cancer Biology” Lectures for undergraduates. Mar - Sept 2000 Fiona Schneiders, University of Cologne, Germany. Fiona undertook a sixmonth internship (research training) in fulfilment of her undergraduate degree requirements. She was the recipient of a scholarship from the German Government to fund her visit. Dec - Jan 2003 Ellen Fox, BSc. Summer vacation scholarship funded by ACCV 17 CV Pritinder Kaur Mar- Sep 2004 Holger Russ, University of Mannheim, Heidelberg, Germany. Holger is undertaking a six-month internship (research training) in fulfilment of his undergraduate degree requirements; and is the recipient of a scholarship from the German Government to fund his visit. 2012 : Guest Lecturer at University of Melbourne, Dept of Anatomy & Cell Biology. B. Postgraduate teaching: 1995-1998 : Teaching Honours students through seminars to Honours students, and serving on assessment panel to determine final Honours grades at The Hanson Center for Cancer Research, Institute for Medical & Veterinary Science, Adelaide Postgraduate students supervised in laboratory setting: Oct – Nov 2005 Shin Sakata, MBBS Monash University. Summer vacation scholarship funded by ACCV. Sept 2010 : Lectured to Masters students at the University of Grenoble, Department of Biology, Grenoble, France. Oct 2010 : President of the PhD Thesis Jury and Thesis Examiner of Sebastien Cadau, at the Albert Bonniot Institut, University Joseph Fourier, Grenoble, France. Sebastien was awarded his PhD with outstanding merit described as “Tres Honorable avec Felicitation”. July 2011 : Co-supervisor for Fidini Antoni B Med Sci student together with Dr Shiva Akbarzadeh at the Alfred Burns Unit. Honours students – Sole Supervisor 1996 1997 1998 2006 Amy Li - graduated with 1st class Honours, continued Ph.D. studies in my laboratory. Rachel Earl - graduated with 2nd class Honours, currently studying Medicine at Flinders University, Adelaide. Hiroaki Tani - graduated with 1st class Honours; PhD obtained from Flinders University, Adelaide. Currently a postdoc in Stanford, California. Yuan Cao – graduated with 1st class Honours; awarded APA and is completing her PhD studies in Cell Biology Program at Peter MacCallum Cancer Centre. 18 CV Pritinder Kaur Ph.D. students – Primary Supervisor 1997-2002 Amy Li Recipient of Australian Postgraduate Award (APA) 1997-2000 for PhD studies. Medical Staff Society Research Prize by the Royal Adelaide Hospital, in 1999. Medical and Biosciences Postgraduate Travelling Fellowship, University of Adelaide, for conference travel and visiting laboratories of collaborators to learn techniques in the USA. Albert M. Kligman Fellowship from the Society for Investigative Dermatology (SID), USA to attend and present her work (oral presentation) at the scientific meeting of the SID in Chicago in 2000. 2001-2005 Richard Redvers Recipient of APA and ACCV (Anti-Cancer Council of Victoria) postgraduate scholarship for PhD studies (2001-2004). Farber fellowship to travel to the Montagna Symposium in Snowmass, Colorado, USA (June 2003) to present his data at a Stem cell Meeting. accepted to attend and present data at the Gordon Conference on “Epithelial Keratinization & Differentiation” in New Hampshire, USA (July 2003). National Stem Cell Centre Premier PhD Scholarship (March – Sept 2004) Awarded PhD degree February 2006. 2007-2011 Lynn Chong PhD student Student is currently writing her thesis. 2008-2009 Christian Orlowski PhD student Recipient of APA PhD scholarship, University of Melbourne Student elected to transfer to a different PhD project at the Baker Institute, Melbourne in 2010. 2011-2014 Devbarna Sinha PhD student Recipient of International postgraduate scholarship Australian National University jointly cosupervised with Prof Chris Parish. C. Medical graduates 2004-2005 Dr Angela Webb MBBS Angela Webb is a trained physician and plastic surgeon in training. Recipient of the prestigious Melville Hughes scholarship (2004-2005) from The Royal Australasian College of Surgeons to undertake an MSc thesis project in my laboratory (February 2004). Awarded Masters of Surgery degree May 2005. Co-supervised PhD student with Dr Wayne Phillips 2003-2006 Dr Daniel Croagh MBBS Daniel Croagh is a trained physician (gastroenterologist) whose PhD research project was cosupervised by me and Dr Wayne Phillips. Recipient of 19 CV Pritinder Kaur Surgeon/Scientist PhD scholarship (2003-2006) from The Royal Australasian College of Surgeons. NHMRC postgraduate scholarship (2004-2005). PhD thesis in April 2006. Awarded PhD degree June 2006. Co-supervised PhD student with Dr Philippe Collas (University of Oslo, Norway) 2008-2010 Ingrid Andersen Recipient of Norwegian PhD scholarship Ingrid Andersen was a visiting student in my lab for a year conducting a collaborative project aimed at investigating epigenetic changes in keratinocyte stem cells and their progeny. She is continuing her PhD in Dr Collas’ lab at present. D. International Workshop on Skin Stem Cell Biology, InStem, India. Taught 22 students stem cell isolation techniques and other skin biology methods during a week long hands on teaching workshop in Bangalore, India. The students included PhD students, and senior researchers including lab heads and industry-based scientists. E. Education Committee at Peter MacCallum Cancer Centre Member of the Education Committee overseeing the needs of all student bodies at undergraduate and postgraduate level. Involvement in strategic planning, implementation of policies for student management F. PhD student Confirmation & Review Committee Member at Peter MacCallum Cancer Centre 2000-present : Member, Postgraduate Student Committee (Molecular & Cell Biology since 2005; Stem Cell Biology 2001-2005). The Committee reviews the progress of all PhD students at Peter Mac for confirmation into the PhD program after their first year. Subsequently, the Committee reviews all PhD students twice a year at all stages through to completion. G. PhD Student mentoring at Peter MacCallum Cancer Centre Informal and formal mentoring of PhD students at Peter MacCallum Cancer Centre. H. PhD Thesis Reviews 2001 – University of Newcastle, NSW. 2002 - University of Western Australia, WA 2003 – University of Queensland, Qld 2010 – University of Grenoble, France, USA. Supervision and mentoring of postdoctoral scientists and research staff I have provided scientific leadership and training for students, postdocs and RAs since 1996. The composition of my research team has changed from an initially Hons/PhD student and RA based laboratory, to one made up of postdoctoral scientists and PhD students in the last 6-7 years. My current team is made up one PhD student and two postdoctoral scientists; and a second laboratory at The Alfred Hospital made up of two staff – a senior postdoctoral scientist and a Research Assistant. 20 CV Pritinder Kaur Over the past 10 years I have attracted and trained several national and international postdoctoral scientists, employing them to work on projects and grants awarded to me personally by the NHMRC, Anti-Cancer Societies and NIH RO1 Project Grants, as well as a variety of philanthropic and commercial bodies. I have trained them to execute internationally competitive stem cell biology research of a high calibre providing both intellectual and technical guidance and mentoring for future career development. I have trained and mentored 8 postdoctoral fellows over the past 11 years all of whom continue to work in science today. My role in directing the Tissue Research Laboratory at The Alfred Hospital within the Burns Unit (in collaboration with the Head of the Burns Unit, Dr Heather Cleland) is (a) to provide intellectual scientific guidance and mentoring for grantsmanship and publications; and (b) to translate my research findings into clinical applications for the better and faster treatment of burns patents. I have also employed and trained 3 technical assistants and 5 Research Assistants over the past 13 years supported through external funding awarded to me. Past and Current Collaborations: The field of keratinocyte biology is rather underrepresented in Australia and as such there is limited scope for collaboration with other investigators, although I have freely provided my expertise in this area to interested investigators. However, I have had some productive interactions with collaborators nationally and internationally that have led to (or will lead to) publications over and above the sharing of reagents, that are listed below. Dr Janine Danks, St Vincent’s Institute for Medical Research, Melbourne. Dr Paul Simmons, Stem Cell Lab, Peter MacCallum Cancer Centre. Dr Nick Saunders, Princess Alexandra Hospital, Brisbane. Dr Rebecca Morris, Columbia University, New York. Dr Steve Gerondakis, Walter & Eliza Hall Institute, Melbourne. Dr Brandon Wainwright, Institute of Molecular Biosciences, Brisbane. Dr Stephanie Edmondson, Murdoch Institute, Melbourne. Dr Stephen Jane, Royal Melbourne Hospital, Melbourne. Dr Leigh Ackland, Deakin University, Melbourne. Dr Wayne Phillips, Peter MacCallum Cancer Centre. Dr Izhak Haviv, Cancer Biology Program, Peter Mac. Dr Denise Galloway, Fred Hutchinson Cancer Research Center, Seattle, USA Prof Ralf Paus, Dept of Dermatology, University of Luebeck, Germany. Prof David Bowtell, Cancer Genomics Program, Peter MacCallum Cancer Centre. Prof George Cotsarelis, University of Pennsylvania, Philadelphia, USA. Dr Bruno Bernard and Dr Michelle Rathman-Josserand, Research & Development, L’Oreal, Paris, France. Dr Edna Hardemann & Dr Stephen Palmer, University of New South Wales Dr Heather Cleland & Dr Shiva Akbarzadeh, Alfred Burns Unit, Alfred Hospital, Melbourne. Dr Ian Smyth, Monash University, Melbourne. Dr Patrick Humbert, Peter MacCallum Cancer Centre, Melbourne. Manuscript reviewer for : Nature Genetics : Ad hoc PNAS : 1-2/year Journal of Cell Biology: 1-2/year Journal of Investigative Dermatology: 4-5/year Experimental Dermatology: 1-2/year Journal of Cell Science: 1-2/year Stem Cells: 4-6/year Int J Cancer: Ad hoc. Biological Procedures Online : Ad hoc 21 CV Pritinder Kaur Stem Cell Research Administrative responsibilities: Lab head duties: Obtaining funding, directing research and managing my lab budget since 1995-1999 in Adelaide and subsequently (1999-present) at Peter Mac. Institutional duties: Aug 2001- Sep 2002 : Served on the Grants sub-committee of the Research Division at Peter Mac which prepares and co-ordinates grant applications to philanthropic societies. This Committee provides important infrastructure support to the Research Division for ad hoc purchases such as major pieces of equipment. 2007 : Member, Peter Mac Group Leader Review Panel. Reviewing scientific and career progress of Senior Faculty. Dec 1999-2005. Member/Lab Head, Stem Cell Biology Program at Peter Mac, contributing to the overall running of the shared Stem Cell Lab (about 40 staff) providing input for scientific excellence in research; maintenance of communal equipment and facilities; space allocation and journal clubs together with 4 group leaders in this area. Acted as proxy for the Head of the Stem Cell Biology Program at Research Management Committee Meetings as required. 2005-present: Member/Lab Head, Cancer Cell Biology Program at Peter Mac meeting regularly with senior colleagues to discuss strategic planning for this group. Dec 1999- present: As a member of the Group Leaders committee, I actively participate in research strategy for the Research Division at monthly Senior Staff meetings and at scientific retreats. Core User Facility Groups: 2001-2005: Member of the Flow Cytometry Core Advisory Committee. 2002-present: Member, Media Kitchen Core Advisory Committee. 2002- 2004: Member, Peter Mac Recruitment committee. 2000-present : Member, Animal Users Group. Conference Organisation: 2001; 2005; 2008 : Member, Organising Committee for the 4th and 6th Peter Mac Symposium held in Nov 2001 and 2005 respectively. Co-Convenor of Peter Mac Wilson’s Prom Workshop held in Oct 2008. Student Reviews and Awards: 2003, 2004 : Member, Review Panel for award of the Peter Mac Medal for PhD students. 2006: Member, Peter Mac Education Committee. 22