Naoyuki Taniguchi MD. PhD.
Program Director, Systems Glycobiology Research Group
Chemical Biology Department, Advanced Science Institute, RIKEN
Endowed Professor of Disease Glycomics (Seikagaku Corporation)
Research Institute for Microbial Diseases, Osaka University
Educational Training MD 1967 Hokkaido University Medical School
PhD. 1972
Hokkaido University
Tani52@wd5.so-net.ne.jp
POSITIONS AND HONORS
10/76-9/77
Visiting Associate Professor, Department of Biochemistry, Cornell University
Medical School, NY, USA
5/79-3/86
Associate Professor, Biochemistry Laboratory, Cancer Institute, Hokkaido
University School of Medicine, Sapporo Japan
4/86-3/06
Professor and Chair, Department of Biochemistry, Osaka University Graduate
School of Medicine, Osaka, Japan
10/05 – present
4/06 -present
Member of Science Council of Japan
Endowed Chair Professor, Department of Disease Glycomics, Research
Institute for Microbial Diseases, Osaka University,
10/08
Program Director of Systems Glycobiology Research Group and team leader of
Disease Glycomics, Advanced Science Institute, RIKEN
Award
2002 Japan Medical Association Prize, Takeda Foundation Prize, International
Glycoconjugate Organization (IGO) Award, 2005 Medal with Purple Ribbon from
Emperor, Japan ,2008 IUBMB medal and lecture
Selected publications 1)Taniguchi N. Nature Chem Biology 3:307-309,2007 2) Taniguchi
N, Miyoshi E, Gu J, Honke K and Matsumoto A. Decoding sugar functions by identifying target
glycoproteins. Curr. Opin. Struct. Biol., 16, 561-566, 2006. 3) Wang X, Inoue S, Gu J, Miyoshi
E, Noda K, Li W, Mizuno-Horikawa Y, Nakano M, Asahi M, Takahashi M, Uozumi N, Ihara S,
Lee S H, Ikeda Y, Yamaguchi Y, Aze Y, Tomiyama Y, Fujii J, Suzuki K, Kondo A, Shapiro S D,
Lopez-Otin C, Kuwaki T, Okabe M, Honke K and Taniguchi N. From The Cover: Dysregulation
of TGF-{beta}1 receptor activation leads to abnormal lung development and emphysema-like
phenotype in core fucose-deficient mice. Proc. Natl. Acad. Sci. U.S.A., 102, 15791-15796, 2005.
4)Yoshimura M, Ihara Y, Matsuzawa Y and Taniguchi N. Aberrant glycosylation
of E-cadherinen hances cell-cell binding to suppress metastasis. J. Biol. Chem., 271,
13811-13815, 1996. 5) Uozumi N, Yanagidani S, Miyoshi E, Ihara Y, Sakuma T, Gao C X,
Teshima T, Fujii S, Shiba T and Taniguchi N. Purification and cDNA cloning of porcine brain
GDP-L-fuc: N-acetyl- -D-glucosaminide: alfa1-6fucosyltransferase. J. Biol. Chem., 271,
27810-27817, 1996. 6) Nishikawa A, Ihara Y, Hatakeyama M, Kangawa K and Taniguchi N.
Purification, cDNA cloning, and expression of UDP-N-acetylglucosamine alfa-D-mannoside
beta1-4N-acetylglucosaminyltransferase III from rat kidney. J. Biol. Chem., 267, 18199-18204,
1992.