BIOGRAPHICAL SKETCH
NAME
POSITION TITLE
Nancy A. Obuchowski, PhD
Vice Chairman
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION
University of New Hampshire, Durham, NH
University of Pittsburgh, Pittsburgh, PA
University of Pittsburgh, Pittsburgh, PA
DEGREE
(if applicable)
YEAR(s)
FIELD OF STUDY
B.S.
MS
PhD
1984
1987
1991
Biology
Biometry
Biometry
A. Positions and Honors
Positions and Employment
1991 – 1997
1997 – 2003
1999 – Present
2003 – present
2005 – present
2009 – present
Assistant Staff, The Cleveland Clinic Foundation, Department of Biostatistics and
Epidemiology with Joint Appointment in Division of Radiology
Associate Staff, The Cleveland Clinic Foundation, Department of Biostatistics and
Epidemiology and Radiology
Joint Appointment in Spine Center in Division of Medicine, The Cleveland Clinic
Foundation
Full Staff, The Cleveland Clinic Foundation, Department of Quantitative Health
Sciences
Vice Chair, Department of Quantitative Health Sciences, The Cleveland Clinic
Foundation
Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western
Reserve University
Other Experience/Professional Membership/Honors
2002, 2003
2003 – 2005
2008
Special Emphasis Panel for National Cancer Institute.
Lead Editor of a series on research methods for radiologists, published in AJR
Fellow of the American Statistical Association
B. Selected Publications
Books and Book chapters
Zhou XH, Obuchowski NA, McClish DL. Statistical Methods in Diagnostic Medicine. 2002. Wiley and
Sons, Inc., New York.
Journal Articles
Jensen MC, Brant-Zawadzki MN, Obuchowski N, Modic M, Malkasian D, and Ross JS. Magnetic
Resonance Imaging of the Lumbar Spine in People Without Back Pain. New England Journal
of Medicine, 1994; 331:69-73.
Obuchowski NA. Multi-reader Multi-modality ROC Studies: Hypothesis Testing and Sample Size
Estimation Using an ANOVA Approach with Dependent Observations. With Rejoinder.
Academic Radiology, 1995; 2:522-529.
Modic MT, Ross JS, Obuchowski NA, Browning K, Cianflocco AJ and Mazanec DJ. Contrast
Enhanced MR Imaging in Acute Lumbar Radiculopathy: A Pilot Study of the Natural History.
Radiology, 1995; 195:429-435.
Obuchowski NA. Multi-reader ROC Studies: A Comparison of Study Designs. Academic Radiology,
1995; 2:709-716.
Powell K, Obuchowski N, Mueller K, Hwang C, Ganobcik S, Sturm B, LaPresto E, Hirsch J, Selzer R,
Nissen J and Cornhill JF. Quantitative Detection and Classification of Single-Leg Fractures in
the Outlet Struts of Bjork-Shiley Convex-Concave Heart Valves. Circulation, 1996; 94:32513256.
Obuchowski NA. Nonparametric Analysis of Clustered ROC Curve Data. Biometrics, 1997; 53:170180.
Obuchowski NA and McClish DK. Sample Size Determination for Diagnostic Accuracy Studies
Involving Binormal ROC Curve Indices. Statistics in Medicine, 1997; 16: 1529-1542
Obuchowski NA, Modic MT, Magdinec M and Masaryk TJ. An Assessment of the Efficacy of
Noninvasive Screening for Patients with Asymptomatic Neck Bruits. Stroke, 1997; 28:13301339.
Meyer JI, Khalil RM, Obuchowski NA, Baus LK. Common Carotid Artery: Variability of Doppler vs.
Velocity Measurements. Radiology, 1997; 204:339-341.
Obuchowski NA. On the Comparison of Correlated Proportions for Clustered Data. Statistics in
Medicine, 1998; 17: 1495-1507.
Obuchowski NA. Sample Size Calculations in Studies of Test Accuracy. Statistical Methods in
Medical Research 1998; 7: 371-392.
Ross JS, Obuchowski N, Zepp R. The Postoperative Lumbar Spine: Evaluation of Epidural Scar over
a 1-year Period. Am J Neuroradiol 1998; 1: 183-186.
Powell KA, Obuchowski NA, Davros WJ, Chilcote WA. Quantitative analysis of breast parenchymal
density: correlation with women’s age. Academic Radiology, 1999; 6: 742-747.
Powell KA, Obuchowski NA, Chilcote WA, Barry MM, Ganobcik SN, Cardenosa G. Film-screen
versus digitized mammography: assessment of clinical equivalence. AJR, 1999; 173: 889-894.
Obuchowski NA, Lieber ML, Powell KA. Data analysis for detection and localization of multiple
abnormalities with application to mammography. Academic Radiology 2000; 7: 516-525.
Obuchowski NA. Sample size tables for receiver operating characteristics studies. AJR 2000; 175:
603-608.
Remer EM, Obuchowski N, Ellis JD, Rice TW, Adelstein JD, Baker ME, Adrenal mass evaluation in
patients with lung carcinoma: a cost-effectiveness analysis. AJR, 2000; 174: 1033-1039.
Obuchowski NA. Can electronic medical images replace hard-copy film? Defining and testing the
equivalence of diagnostic tests. Statistics in Medicine 2001; 20: 2845-2863.
Obuchowski NA, Graham RJ, Baker ME, Powell KA. Ten criteria for effective screening: their
application to multi-slice CT screening for pulmonary and colorectal cancers. AJR 2001; 176:
1357-1362.
Obuchowski NA. Special Topics I: ROC curves and their use in Radiology. Radiology 2003; 229:3-8.
Obuchowski NA. Special Topics III: Bias. Radiology 2003; 229:617-21.
Obuchowski NA, Lieber M. The effect of misclassification in screening trials: a simulation study.
Contemporary Clinical Trials 2008; 29: 125-135.
Obuchowski NA, Lieber M. The effect of misclassification in screening trials: a simulation study.
Contemporary Clinical Trials 2008; 29: 125-135.
Obuchowski NA. Estimating sample size for a randomized clinical trial of lung cancer
screening. Contemporary Clinical Trials 2008; 29: 466-77.
Obuchowski NA, Mazzone PJ, Dachman AH. Bias, underestimation of risk, and loss of statistical
power in patient-level analyses of lesion detection. European Radiology 2010; 20: 584-594.
Obuchowski NA, Meziane M, Dachman AH, Lieber ML, Mazzone PJ. What's the control in studies
measuring the effect of computer aided detection (CAD) on observer performance? Academic
Radiology. In press.