WILLIAM F. MILTON FUND
of
HARVARD UNIVERSITY
APPLICATION KIT
Harvard Medical School, Sponsored Programs Administration, 25 Shattuck Street, Suite 509, Boston, MA 02115
Rev. 9/01
WILLIAM F. MILTON FUND
APPLICATION
ELIGIBILITY, GUIDELINES AND INSTRUCTIONS
The bequest of the William F. Milton Fund makes funds available to support research conducted by faculty
members of Harvard University. An advisory inter-faculty Milton Fund Committee has been appointed to assist
in the allocation of Milton Fund income. This Committee administers the funds to facilitate new approaches,
initiate new projects, and in particular, assist junior members of the faculties in establishing their research
programs. The amount allocated to any one program is comparatively small and the duration of support is
limited to one year.
ELIGIBILITY
The annual allocation of the William F. Milton Fund of Harvard University primarily supports investigations of
a temporary nature conducted within the University that meet the following eligibility requirements:
1.
Applicants must be voting members of Harvard University Faculty holding appointments of three years
or more. Generally, this includes a lecturer with a 3-year appointment, Assistant Professor or above (these
titles may vary among schools), or Junior Fellows of the Harvard Society of Fellows.
2.
Such investigations must be of a: (1) medical; (2) geographical; (3) historical; or (4) scientific nature.
3.
The investigation must:
a. Be in the interests of or for promoting the physical and material welfare and prosperity of the human
race (rather than its spiritual, intellectual or aesthetic welfare);
b. Assist in the discovery and perfecting of any special means of alleviating or curing human disease;
or c. Investigate and determine the value or importance of any discovery or invention.
4.
Applicants having substantial active support ($200K or more not including applicant’s salary and fringe
benefits), which runs concurrently with the Milton Fund’s award period will be assigned a very low priority
rating for funding.
5.
Ineligible: Instructors, post-doctoral fellows, residents, those with pending and/or “anticipated” promotions
in their academic appointment status at the time of application submission, and anyone who has received a
Milton Fund Grant within the previous five years are not eligible for funding.
APPLICATION GUIDELINES
DEADLINE:
Applications must be received before November 13th @ 5pm. Applications postmarked
November 13th will not be accepted.
AWARD:
$35,000 for one year beginning January 1st.
APPLICATIONS:
Must be typed using a 10 or 12pt font
PLEASE NOTE:
If applications received are incomplete and/or missing appropriate signatures, they will be
administratively denied and returned without review.
INSTRUCTIONS
Rev. 9/01
SUBMIT APPLICATIONS WITH CONTENTS IN THE FOLLOWING ORDER:
1. Application Face Page: Complete all administration and research information.
2.
Assurance of Compliance:
A. Location of Research: HMS applicants must complete this section according to standard HMS
policy. Applicants whose research will be conducted at an HMS affiliate or other Harvard school must
complete the section and obtain the signature of an authorizing official from that institution (usually
the Sponsored Programs Office).
B. Animal and Human Subjects: Applicants using either animals or humans in the proposed research
must submit a copy of the protocol and approval letter for our records.
3.
Summary Statement, Narrative and References:
A. Include a summary statement of the research proposal (not to exceed 200 words) in layman's terms.
B. Describe the proposed research in sufficient detail to enable the reviewing committee to appraise it.
A level of detail typical of a Scientific American article is appropriate. Include a brief summary of
preliminary work or other background material, objectives, and scope of work not to exceed 4
double-spaced pages with one-inch margins on all sides. Use a 10 or 12pt font. Keep references on
separate pages not to exceed 2 pages in length. The summary statement, narrative and the
reference section should not exceed 7 pages. Make copies of the form page if needed.
4.
Budget and Justification Forms: Provide a detailed budget and justification on the enclosed forms. The
Budget Justification is a narrative of each line item explaining why it is essential to the proposed research
project. Also, explain how the cost was calculated. The total budget must not exceed $35,000.
Personnel: No individual above the level of post-doctoral fellow may receive salaries, stipends, or
special remuneration from the Milton Fund. Personnel supported by Milton Funds may not conduct any
course or instruction offered for academic credit. An occasional lecture, not regularly scheduled in a
course of instruction, will not be regarded as a violation of this provision. Technicians and laboratory
assistants may be paid to the extent that they work on Milton Fund supported investigations. Requests
for payment of secretaries and other personnel usually considered office employees must be justified in
terms of the proposed research. Fringe benefits must be calculated according to your institutional rate.
Equipment: Only expenditures for the temporary purposes of the proposed investigation are allowable
for Milton Fund grants. Funds for large pieces of equipment planned to improve the general facilities of
a laboratory are not usually approved. Funds for maintenance or service contracts are usually not
allowable. Equipment becomes the property of Harvard University upon termination of the
project.
Travel: Travel to collect specimens or obtain data necessary to conduct the proposed research is
allowable and must be explained thoroughly in the budget justification. Travel to scientific meetings is
not an allowable budget item.
Supplies: All research related supplies are allowed.
Overhead: No amount for indirect or administrative expenses may be included in a Milton Fund grant.
Rev. 9/01
Rev. 9/01
INSTRUCTIONS (continued)
5.
Other Support: Document all other support pending and active in the format provided. No other format
will be accepted. Please include any "start-up" packages and/or tenure-transfer funding if applicable. Also
include a short narrative (one paragraph) which demonstrates the applicants need for funding.
6.
Biographical Sketch: Provide a bio-sketch for the applicant and any individual at the post-doctoral
fellow level or above participating in the project. Three pages only. NIH format is acceptable.
7.
Letter of Reference: Required for Junior Fellows of the Harvard Society of Fellows only.
8.
Proof of Appointment: A copy of your current Harvard University Appointment form is required.
9.
Terms and Conditions: (Completed and signed) Please read this document carefully. Once it is signed,
you are agreeing to comply with the terms and conditions as they pertain to the Milton Fund.
MAILING INSTRUCTIONS
Submit original and 9 copies (stapled) to:
Milton Fund Committee/Sponsored Programs Administration
Harvard Medical School
Building A, Suite 509
25 Shattuck Street
Boston, MA 02115
If you have any questions concerning this Application Kit, please contact The Milton Fund Coordinator:
Kemith LeBlanc
Rev. 9/01
Phone: (617) 432-2663
Fax: (617) 432-2651
Email: Kemith_LeBlanc@hms.harvard.edu
APPLICATION FOR SUPPORT
THE WILLIAM F. MILTON FUND
RESEARCH INFORMATION
Principal Investigator:
Academic Title:
Proposed Funding: $
Project Period:
Title of Project:
Type of Investigation: Medical___ Geographic___ Historical____ Scientific____
Purpose of the Proposed Study (please check one or more of the following):
It is in the interest of, or for promoting the physical and material welfare and prosperity of the human race.
It is to assist in the discovery and perfection of a special means of alleviating or curing human disease.
It is to investigate and determine the value of importance of a discovery or invention.
Other Support: Total Active Direct Cost (excluding indirect costs and applicant’s salary and fringe) support from other resources
which run concurrently with the requested Milton Fund project period.
Total Active Support: $
Total Pending Support: $
Previous Milton Fund Support: $
Previous Milton Fund Award Period:
ADMINISTRATIVE INFORMATION
Harvard Tub #:
Harvard Org #:
Principal Investigator Address:
School/Affiliate
Street
Telephone: (
Dept. Name
Building/Room #
)
FAX: (
City
)
State
Zip Code
State
Zip Code
Email Address:
Financial Administrator:
Title:
(person with signature authority for accounts payable in your dept.)
Address:
School/Affiliate
Street
Telephone: (
Dept. Name
Building/Room #
)
FAX: (
City
)
Email Address:
Page 1
Rev. 9/01
APPLICATION FOR SUPPORT
THE WILLIAM F. MILTON FUND
Assurance of Compliance
ANIMAL AND HUMAN SUBJECTS
1. Does this research proposal involve the use of animals YES__ NO__
If YES, Have you submitted a protocol to the HMA- Animal Research Committee? Yes___ No___
If Yes, date of your latest approval- ___/___/____Protocol #
If No, contact the Animal Experimentation Coordinator/Human Studies Coordinator at (617)432-0651.
2. Does this research proposal involve the use of humans? YES__ NO__
If Yes, is the protocol exempt from review according to PHS guidelines? Yes___ No___
Exemption Number _________
If Non-Exempt, has a protocol been sent to HMS Human Studies Committee? Yes___ No___
If Yes, date of your latest approval- ___/___/____Protocol #
If No, call Human Studies Coordinator at (617)432-0651 for assistance
LOCATION OF RESEARCH
Harvard University : Name of School
Affiliate of Harvard University: Name of Affiliate Institution
If research is conducted at a location other than Harvard Medical School, then a research administration official at the affiliated
institution must approve the use of their facility by signing below.
SIGNATURES OF APPROVAL
Name & Title of Institutional Research Administration Official
Signature
(Date)
(ONLY REQUIRED IF RESEARCH NOT AT HMS)
Signature: Principal Investigator
(Date)
Signature: Department Chairperson
(Date)
________________________________________________
Typed Name of Department Chairperson
(REQUIRED OF ALL APPLICANTS)
(REQUIRED OF ALL APPLICANTS)
Page 2
Rev. 9/01
APPLICATION FOR SUPPORT
THE WILLIAM F. MILTON FUND
Research Narrative and References
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Rev. 9/01
APPLICATION FOR SUPPORT
THE WILLIAM F. MILTON FUND
Detailed Budget
Project Period: January 1,
Itemized
Budget
Through December 31,
Base
Salary
%
Project
Effort Salary
Fringe
Benefits
Total
Requested
A. Personnel (name & role)
Professional
Non-Professional
A. Subtotal Personnel
$
B. Subtotal Other Research Expenses
$
Total Requested (a + b):
$
B. Other Research Expenses
Equipment
Travel
Supplies
Consultants
Miscellaneous (detail)
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APPLICATION FOR SUPPORT
THE WILLIAM F. MILTON FUND
Budget Narrative
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Rev. 9/01
APPLICATION FOR SUPPORT
THE WILLIAM F. MILTON FUND
Other Support Form
Sample Format
NAME OF INDIVIDUAL
ACTIVE/PENDING
Project Number (Principal Investigator)
Source
Title of Project (or Subproject)
Dates of Approved/Proposed Project
Annual Direct Costs
Percent Effort
The major goals of this project are…
OVERLAP (summarized for each individual)
Samples
ANDERSON, R.R.
ACTIVE
2 R01 HL 00000-13 (Anderson)
NIH/NHLBI
Chloride and Sodium Transport in Airway Epithelial Cells
3/1/97 – 2/28/00
$186,529
30%
The major goals of this project are to define the biochemistry of chloride and sodium transport in airway epithelial cells and clone
the gene(s) involved in transport.
4/1/94 – 3/31/99
$122,717
5 R01 HL 00000-07 (Baker)
NIH/NHLBI
Ion Transport in Lungs
10%
The major goal of this project is to study chloride and sodium transport in normal and diseased lungs.
9/1/96 – 8/31/98
$43,123
R000 (Anderson)
Cystic Fibrosis Foundation
Gene Transfer of CFTR to the Airway Epithelium
10%
The major goals of this project are to identify and isolate airway epithelium progenitor cells and express human CFTR in airway
epithelial cells.
PENDING
DCB 950000 (Anderson)
National Science Foundation $82,163
Liposome Membrane Composition and Function
12/01/98 – 11/30/00
20%
The major goals of this project are to define biochemical properties of liposome membrane components and maximize liposome
uptake into cells.
OVERLAP
There is scientific overlap between aim 2 of NSF DCB 950000 and aim 4 of the application under consideration. If both are
funded, the budgets will be adjusted appropriately in conjunction with agency staff.
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Rev. 9/01
WILLIAM F. MILTON FUND
Terms, Conditions, & Financial Administration Guidelines
Awards from the William F. Milton Fund, a Harvard University Endowment Fund, must be administered through a Harvard account
number and thus are handled differently from sponsored awards administered directly through your own institution.
You should contact the administrator of your department to learn how to access your Milton funds. A list of some general Harvard
rules and procedures concerning the processing of Milton Fund expenditures follows for your information.

The Milton Fund is similar to a sponsored research account in that you must adhere to the line item budget submitted. It is not to
be used as a discretionary account (i.e., expenses incurred for other departmental purposes). Rebudgeting is permitted under
limited conditions only. Changes between expense categories are allowable provided (1) the categories were approved on the
original application budget; (2) the expenses are allowed according to general policy; (3) the total amount of the award is not
exceeded; (4) the scope of the project is in no way modified. Requests for budgetary changes that DO NOT adhere to these
conditions must be made in writing to the Milton Fund Committee.

Invoices for expenditures are processed through the on-line Webvoucher system or paid through use of the HU Pcard (Purchasing
Card). Invoices processed via Webvoucher with the Webvoucher number clearly indicated in the upper right hand corner of the
invoice should be sent to Harvard University Accounts Payable, 380 Holyoke Center, 1350 Massachusetts Avenue, Cambridge,
MA 02138. Please do not submit invoices to the Milton Fund Coordinator.

The Milton Fund awardee must not use personal funds to pay for services rendered by either companies or individuals. All
invoices must be paid directly by Harvard University’s accounts payable department. If the awardee does pay for expenditures,
he/she must provide the original receipt(s) for the purchase. If original receipts are unavailable, a copy of the credit card bill
and/or a copy of the front and back of the canceled check showing payment are required.

It is your responsibility to manage this account. Harvard will not accept responsibility for cost over-runs.

Milton Fund accounts are closed ninety (90) days after the expiration date of the grant period; any unexpended balance will be
returned to the Milton Fund for future award cycles. Deficits must be cleared by the end of the ninety days. An alternate
Harvard account must be provided by your department in the event over-expenditures are not removed within this time period.

If you have any accounting related questions concerning your award, please contact Nancy Galvin in the General Accounting
Office at 496-3039.

No-cost extensions: Requests must be received, in writing, by the Committee at least thirty (30) days prior to the expiration
date of your grant. No additional money will be made available to you; extensions are granted for a period of time ranging from
three months to one year.

Final Reports: Upon completion of your research project please submit a (one page) report to the Milton Fund Committee. In
addition, please acknowledge support from the Milton Fund in any publication.

All correspondence pertaining to this grant, except invoices, should be directed to the Milton Fund Coordinator, by mail
Sponsored Programs Administration, Harvard Medical School, 25 Shattuck Street, Building A, Suite 509, Boston, MA 02115,
telephone (617) 432-2663, or fax (617)432-2651.
Signature: Award Recipient
(Date)
Signature: Financial Administrator (Date)
Name:(please type)
Name: (please type)
EMAIL:
EMAIL:
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