BIOGRAPHICAL SKETCH
POSITION TITLE
Dr Varvaresou Athanasia,
Associate Professor in Cosmetology,
Pharmacist
Department of Aesthetics and
Cosmetology, Technological
Educational Institution of Athens
Tel: +30 2105385640
Fax: +30 2105385861
Email: avarvares@teiath.gr
Academic Appointments
1985-1989
1990-1991
1991-1996
1996-1996-2007
2007-2012
2012--
Bachelor, School of Pharmacy, University of Athens, Greece
Doctoral Fellow, School of Pharmacy, University of Heidelberg, Germany
Ph.D. studies, School of Pharmacy, University of Athens, Greece
Post-Doctoral Fellow, School of Pharmacy, University of Athens, Greece
(research programs)
Assistant in Research and Education, Department of Aesthetics and
Cosmetology, Technological Educational Institution of Athens
Assistant Professor in Cosmetology, Department of Aesthetics and
Cosmetology, Technological Educational Institution of Athens
Associate Professor in Cosmetology, Department of Aesthetics and
Cosmetology, Technological Educational Institution of Athens
Jobs
1999-2002
2002--
Hospital Pharmacist, Public Hospital Spiliopoulio, Athens, Greece
Consultant in the Development of Drugs and Cosmetics
Research programs
ΕLKE (Κ.Α 70/4/1411, School of Pharmacy, University of Athens), PENED (Κ.Α
70/3/2742, School of Pharmacy, University of Athens), EPEAEK (K.A 70/3/3739,
School of Pharmacy, University of Athens), THALIS (Department of Aesthetics and
Cosmetology, Technological Educational Institution of Athens) και ARCHIMEDES III
(Department of Aesthetics and Cosmetology, Technological Educational Institution of
Athens)
Teaching Activity
Cosmetology I, II, III and Specific Cosmetology [Department of Aesthetics and
Cosmetology, Technological Educational Institution of Athens, (Under-graduate)],
Photoaging and oxidative stress: Topical application of cosmetics [Department of
Aesthetics and Cosmetology, Technological Educational Institution of Athens and
Medical School of Athens (Post-graduate], Pharmaceutical chemistry laboratory lessons
(School of Pharmacy, University of Athens (Post-graduate)].
Publications: 30
Presentations in International Conferences: 20
Citations: 237
Total Impact factor: 26.185
Αuthor:
1. Varvaresou A. «Specific Cosmetology», KAFKAS Publications, Athens 2011,
ISBN: 978-960-6650-48-9
2. Tsirivas E and Varvaresou A. «Laboratory lessons in Cosmetology I», ΤΕΙ
Athens
3. Tsirivas E and Varvaresou A. «Laboratory lessons in Cosmetology III», ΤΕΙ
Athens
4. Varvaresou A. «Laboratory lessons in Specific Cosmetology», ΤΕΙ Athens
Reviewer: Food and Chemical Toxicology (Elsevier), Household and Personal Care
(Tecnoscienze), Current Microbiology (Springer) και Process Biochemistry (Elsevier)
Other activities
1. Responsible of Laboratory of Cosmetology, Department of Aesthetics and
Cosmetology, Technological Educational Institution of Athens
2. Responsible of Division of Aesthetics, Department of Aesthetics and
Cosmetology, Technological Educational Institution of Athens
Publications
Α1. A. Varvaresou, A. Tsotinis, A. Papadaki-Valiraki and Th. Siatra-Papastaikoudi
“New Azathioxanthones: Synthesis and Cytotoxicity”.
Biorganic and Medicinal Chemistry Letters 1996, 6, No.7, 861-864.
Α2. A. Varvaresou, A. Tsotinis, Th. Siatra-Papastaikoudi*, A. Papadaki-Valiraki,
D. E. Thurston, T. C. Jenkins and L. R. Kelland
“Novel Imidazothioxanthones: Synthesis, DNA Binding and Cytotoxicity”.
Biorganic and Medicinal Chemistry Letters 1996, 6, No.7, 865-870.
Α3. K. R. Fox, D. E. Thurston, A. Varvaresou, A. Tsotinis and Th. SiatraPapastaikoudi
“A Novel Series of DNA Triple Helix-Binding Ligands”.
Biochemistry and Biophysics Research Communications 1996, 224, 717-720.
Α4. A. Varvaresou, A. Tsotinis, Th. Siatra-Papastaikoudi* and T. Calogeropoulou
“New Pyrazole-Annulated Azathioxanthenes as Potential Intercalators: Synthesis
and Structure Elucidation”.
Journal of Heterocyclic Chemistry, 1996, 33, 831-835.
Α5. A. Varvaresou, A. Tsotinis, A. Papadaki-Valiraki and Th. SiatraPapastaikoudi*
“Synthesis and Structure Elucidation of New Cytotoxic Azathioxanthones”.
Journal of Heterocyclic Chemistry, 1996, 33, 917-921.
Α6. A. Tsotinis, A. Varvaresou, T. Calogeropoulou, Th. Siatra-Papastaikoudi* and
Α. Tyligada
“Synthesis and Antimicrobial Evaluation of Indole containing Derivatives of 1,3,4Thiadiazole, 1,2,4-Triazole and their open-chain counterparts”.
Arzneimittel Forschung/Drug Research 1997, 47, 307-310.
Α7. A.Varvaresou, Th. Siatra-Papastaikoudi, A. Tsotinis, A. Tsantili-Kakoulidou
and A. Vamvakides
“Synthesis, Lipophilicity and Biological Evaluation of Indole containing Derivatives of
1,3,4-Thiadiazole and 1,2,4-Triazole”
Il Farmaco 1998, 53, 320-326.
Α8. A.Varvaresou, Th. Siatra-Papastaikoudi, A.Tsantili Kakoulidou and Ε. Τyligada
“Synthesis and Biological Evaluation of Indole containing Derivatives of
Thiosemicarbazides and their Cyclic 1,2,4-Triazole and 1,3,4-Thiadiazole Analogs”
Arzneimittel Forschung/Drug Research 2000, 50, 48-54.
Α9. A. Tsantili-Kakoulidou, A.Varvaresou, Th. Siatra-Papastaikoudi, O.A. Raevsky
“Α comprehensive investigation of the partitioning and hyrogen bonding behavior of
indole containing derivatives of 1,3,4-Thiadiazole and 1,2,4-Triazole by means of
Experimental and Calculative Approaches ”
Quantatine Structure Activity Relationships 1999, 18, 482-489.
Α10. Α. Varvaresou, K. Iakovou, E. Filippatos, C. Souli, T. Calogeropoulou, I.
Ioannidou, A. Kourounakis. C. Pannecouque, M. Witvrouw , E. Padalko, J. Neyts, E. De
Clercq, A. Tsotinis
«Synthesis, Antiretroviral ant Antioxidant Evaluation of a Series of new Benzo[b]furan
Derivatives»
Arzneimittel Forschung/Drug Research 2001, 51 (1),156-162.
A11. K. Iakovou, A. Varvaresou, A. P. Kourounakis, K. Stead, D. Sugden, A. Tsotinis*
«Design, synthesis and biological evaluation of novel conformationally restrained
melatoninergic analogs»
Journal of Pharmacy and Pharmacology 2002, 54, 147-156.
A12. A. Varvaresou and K. Iakovou
“Derivatives of 5-Oxy-pyrido[2,3-b]quinoxaline-9-carboxylic acid: A new Tricyclic
System Useful for the Synthesis of Potential Intercalators”
Journal of Heterocyclic Chemistry 2002, 39, 1173-1176.
Α13. Α. Varvaresou, E. Tsaoula and E. Tsirivas
“The influence of the addition of melatonin to a magnesium ascorbyl phosphatecontaining formulation on the mechanical properties of human skin”
Rewiew of Clinical Pharmacology and Pharmacocinetics, 2004, 18, 177-181.
Α14. A. Varvaresou, K. Iakovou, E. Gikas, I. Fichtner, H.H. Fiebig, L.R. Kelland, J.A.
Double, M.C. Bibby and H.R. Hendriks
“Antitumor Activity of Imidazothioxanthones in Murine and Human Tumor Models In
Vitro and In Vivo”
Anticancer Research 2004, 24, 907-920.
A15. K. Iakovou, A.Varvaresou, G. Bruni, P. Massarelli, A. Vavayannis, and M.
Kazanis
“Anti-inflammatory and Analgesic Activity οf two dicyclic analogues of Acetaminophen
and its regioisomer 3-Hydroxyacetanilide”
Pharmaceutical Chemistry Journal, 2004, 38, 239-242..
A16. A. Varvaresou, E. Tsirivas, E. Tsaoula, E. Protopapa
“Oxidative Stress, Photoaging and Topical antioxidant Protection”
Review of Clinical Pharmacology and Pharmacokinetics, 2004, 18, 261-266.
A17. A. Varvaresou, E. Tsirivas, E. Tsaoula, E. Protopapa
“Synthetic colorants commonly used in lipsticks”
Review of Clinical Pharmacology and Pharmacokinetics, 2005, 18, 11-16.
A18. A. Varvaresou, E. Tsirivas, E. Tsaoula
“Isothiazolinone Biocides as Preservatives in Cosmetics”
Review of Clinical Pharmacology and Pharmacokinetics, 2005, 19, 105-108.
A19. A. Varvaresou, E. Tsirivas, E. Tsaoula, E. Protopapa
“The influence of magnesium ascorbyl phosphate on moisturization of stratum
corneum”
Review of Clinical Pharmacology and Pharmacokinetics, 2005, 19, 139-142.
A20. A. Varvaresou
“Percutaneous absorption of organic sunscreens”
Journal of Cosmetic Dermatology, 2006, 5, 53-57.
A21. A. Varvaresou, E. Tsirivas, K. Iakovou, E. Gikas, Z. Papathomas, A.
Vonaparti, I. Panderi
“Development and validation of a reversed-phase ion-pair liquid chromatography method
for the determination of magnesium ascorbyl phosphate and melatonin in cosmetic
creams”
Analytica Chimica Acta, 2006, 573-574, 284-290.
Α22. S. Papageorgiou, A. Varvaresou, S. Hatziantoniou, E. Tsirivas, C. Demetzos, G.
Papaioannou.
“Photostability of retinoids: The influence of the container”
Review of Clinical Pharmacology and Pharmacokinetics, 2007,21, 49-53.
Α23. S. Papageorgiou, A.Varvaresou and E.Tsirivas
“The Development of Self- preserving Cosmetics”
Review of Clinical Pharmacology and Pharmacokinetics, 2008, 22, 455-460
Α24. Varvaresou A., Papageorgiou S., Tsirivas E., Protopapa E., Kintziou H., Kefala V.
and Dementzos C.
“Self-preserving cosmetics”
International Journal of Cosmetic Science, 2009, 31, 163-175.
Α25. S. Papageorgiou., A.Varvaresou, E. Tsirivas and C. Demetzos
“New alternatives to cosmetics preservation”
Journal of Cosmetic Science 61: 107-123 (2010).
A26. A. Varvaresou and K. Iakovou
“Molecular Modeling Study of Intercalation Complexes of Tricyclic Carboxamides
with d(GCGC)2, d(CGCG)2 and d(CGCGCG)2”.
Journal of Moelecular Modeling 8: 2041-2050 (2011).
A27. A. Varvaresou and S. Papageorgiou
“The development of self-preserving gels”
Household and Personal Care Today, 18-21 (2011)
A28. Papagianni P., Varvaresou A., Papageorgiou S., Panderi I. Development and
validation of an ion-pair RP-HPLC method for the determination of oligopeptide-20 in
cosmeceuticals Journal of Pharmaceutical and Biomedical Analysis 56:645-649 (2011)
A29. Kefala V., Kintziou H., Protopapa E., Varvaresou A., Papageorgiou S., Raikou V.
Tyrosinase inhibitors from natural Sources for Potential use in the Aesthetic and
Cosmetology Practice Review of Clinical Pharamacology and Pharmacocinetics
(International
Edition) 25: 65-68 (2011)
A30. Varvaresou Α., Papageorgiou S., Protopapa E. and Katsarou A. Efficacy and
tolerance study of an oligopeptide with potential anti-aging activity Cosmetics,
Dermatological Sciences and Applications 1: 133-140 (2011)
Research Interests
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Synthesis and pharmacological study of new compounds with antitumor, antiinflammatory, antimicrobial and antioxidant activities (Xanthenes, benzofurans,
thiadiazoles, melatoninergic derivatives, pyridoquinoxalines).
Molecular modeling of DNA intercalative compounds
NMR Spectroscopy
Interaction of cosmetic dyes with DNA (xanthenes)
Preservation of cosmetics-thiadiazoles
Self-preserving cosmetics
Influence of antioxidant compounds on human skin elasticity
Development of anti-aging cosmetics
Influence of oligopeptides on human skin elasticity and wrinkles
Efficacy tests of cosmetics: Skin elasticity, profilometry, sebum, moisturization
etc
Lipophilicity structure-activity relationships
UVA and UVB sunscreens
Skin penetration