PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
OR figures of all explanatory variables: comparison among 3 sets of models
Part 1: 3-month survival
Predictor
3-month
survival model selected as
final models in the paper
adjusted OR†
Diagnoses at PMV onset (excluding respiratory failure)
Septicemia
Other infectious and parasitic diseases
Neoplasms
Diabetes mellitus
Nutritional deficiencies
Fluid and electrolyte disorders
Other endocrine/nutritional/metabolic diseases & immunity disorders
Coagulation and hemorrhagic disorders
Other diseases of the blood and blood-forming organs
Mental illness
Diseases of the nervous system and sense organs
Hypertension
Heart valve disorders
Acute myocardial infarction and coronary atherosclerosis
Cardiac dysrhythmias
Other diseases of the heart
Cerebrovascular diseases
Other diseases of the circulatory system
Pneumonia
Chronic obstructive pulmonary disease and bronchiectasis
Asthma
Other diseases of the respiratory system
Gastrointestinal hemorrhage
Other diseases of the digestive system
0.52
0.79
0.30
0.78
0.74
0.99
0.83
0.40
1.02
1.27
1.07
1.32
0.92
0.88
0.89
0.70
1.06
0.60
0.81
1.14
0.88
0.83
0.72
0.84
-1-
**
**
**
**
*
**
**
*
**
**
**
**
**
**
**
**
3-month
survival model that
excluded the year variable
adjusted OR†
0.52 **
0.79 **
0.30 **
0.78 **
0.74 *
0.99
0.83 **
0.40 **
1.02
1.27 *
1.07
1.33 **
0.91
0.89
0.89
0.70 **
1.06
0.60 **
0.82 **
1.14 **
0.88
0.83 **
0.71 **
0.84 **
3-month
survival model using
stepwise regression
adjusted OR†
0.52 **
0.79 **
0.30 **
0.75 **
0.74 **
0.84 *
0.40 **
1.26 *
1.08
1.33 **
0.87 *
0.91
0.70 **
0.60 **
0.81 **
0.84 **
0.73 **
0.84 **
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
Predictor
3-month
survival model selected as
final models in the paper
adjusted OR†
Acute and unspecified renal failure
Urinary tract infections
Other diseases of the genitourinary system
Complications: pregnancy/childbirth/puerperium
Diseases of the skin and subcutaneous tissue
Diseases of the musculoskeletal system and connective tissue
Congenital anomalies
Spinal cord injury
Intracranial injury
Other injury and poisoning
Symptoms; signs; and ill-defined conditions and factors
Shock
Parkinson's disease
Heart failure
Alcoholic liver disease
Non-alcoholic liver disease
0.39
1.25
0.78
0.80
0.82
0.93
0.99
2.00
1.16
0.99
0.89
0.42
1.80
0.77
1.18
0.60
Multiple sclerosis/Other hereditary & degenerative nervous system
conditions
0.98
3-month
survival model that
excluded the year variable
adjusted OR†
**
**
**
**
**
**
**
**
**
Chronic renal failure
0.44 **
Disease history (Number of admissions for the disease in the previous year; excluding respiratory failure)
Septicemia
1.14 **
Other infectious and parasitic diseases
0.93 **
Neoplasms
0.91 **
Diabetes mellitus
0.98
Nutritional deficiencies
0.99
Fluid and electrolyte disorders
0.96
Other endocrine/nutritional/metabolic diseases & immunity disorders
1.03
-2-
0.40 **
1.25 **
0.78 **
0.80
0.82 **
0.94
1.00
1.99 **
1.15
0.99
0.89
0.42 **
1.80 **
0.77 **
1.19
0.60 **
3-month
survival model using
stepwise regression
adjusted OR†
0.39 **
1.24 **
0.78 **
0.82 **
1.94 **
1.13
0.42 **
1.72 **
0.76 **
0.60 **
0.97
0.44 **
0.43 **
1.15 **
0.93 **
0.92 **
0.98
0.99
0.96
1.03
1.14 **
0.94 *
0.91 **
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
Predictor
3-month
survival model selected as
final models in the paper
adjusted OR†
Coagulation and hemorrhagic disorders
Other diseases of the blood and blood-forming organs
Mental illness
Diseases of the nervous system and sense organs
Hypertension
Heart valve disorders
Acute myocardial infarction and coronary atherosclerosis
Cardiac dysrhythmias
Other diseases of the heart
Cerebrovascular diseases
Other diseases of the circulatory system
Pneumonia
Chronic obstructive pulmonary disease and bronchiectasis
Asthma
Other diseases of the respiratory system
Gastrointestinal hemorrhage
Other diseases of the digestive system
Acute and unspecified renal failure
Urinary tract infections
Other diseases of the genitourinary system
Complications: pregnancy/childbirth/puerperium
Diseases of the skin and subcutaneous tissue
Diseases of the musculoskeletal system and connective tissue
Congenital anomalies
Spinal cord injury
Intracranial injury
Other injury and poisoning
1.07
0.85
0.99
1.03
1.00
0.99
1.00
1.05
1.14
1.11
1.04
1.14
1.00
1.04
1.03
1.04
1.00
1.24
0.96
0.96
0.82
0.94
0.97
0.85
1.31
1.15
0.93
-3-
**
**
**
**
**
*
*
*
3-month
survival model that
excluded the year variable
adjusted OR†
1.07
0.86 **
1.00
1.03
1.00
0.99
1.00
1.05
1.14 **
1.11 **
1.05
1.15 **
1.00
1.03
1.03
1.04
1.00
1.24 **
0.97
0.96
0.81
0.94 *
0.97
0.85
1.31
1.16 *
0.93 *
3-month
survival model using
stepwise regression
adjusted OR†
0.85 **
1.17 **
1.12 **
1.15 **
1.23 **
0.96
0.95 *
0.93 *
1.33 *
1.16 *
0.92 **
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
Predictor
3-month
survival model selected as
final models in the paper
adjusted OR†
Symptoms; signs; and ill-defined conditions and factors
Shock
Parkinson's disease
Heart failure
Alcoholic liver disease
Non-alcoholic liver disease
Multiple sclerosis/Other hereditary & degenerative nervous system
conditions
Chronic renal failure
0.96
1.32
0.98
0.94
0.94
0.86
**
*
**
1.11
3-month
survival model that
excluded the year variable
adjusted OR†
0.96
1.33 **
0.98
0.94 *
0.94
0.86 **
3-month
survival model using
stepwise regression
adjusted OR†
1.33 **
0.94 *
0.86 **
1.11
1.10
0.91
**
0.91 **
0.90 **
0.89
**
0.89 **
0.91 **
35–44
0.67
**
0.67 **
0.68 **
45–54
0.67
**
0.68 **
0.69 **
55–64
0.62
**
0.62 **
0.64 **
65–74
0.44
**
0.45 **
0.46 **
75–84
0.36
**
0.36 **
0.38 **
≥85
0.29
**
0.29 **
0.30 **
1.06
**
Northern region
0.89
*
0.89 *
0.89 *
Central region
1.13
**
1.14 **
1.13 **
Southern region
1.04
1.05
1.04
Gender (ref: female)
Male
Age group (ref: 17–34)
PMV incidence year
continuous variable in the value range: [1998, 2002]
1.06 **
Branch of hospital location (ref: Taipei)
-4-
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
3-month
survival model selected as
final models in the paper
adjusted OR†
Predictor
Kao-Ping region
0.89
Eastern region
0.92
*
3-month
survival model that
excluded the year variable
adjusted OR†
3-month
survival model using
stepwise regression
adjusted OR†
0.89 *
0.89 *
0.93
0.91
Hospital type (ref: medical centre)
Regional hospital
Local hospital
0.92
*
0.92 *
0.90
*
*
0.89
0.93
0.90 *
NHI registration location (ref: big city)
Small city or town
1.02
1.02
1.02
Remote or rural area
0.95
0.96
0.96
0.85 **
0.85 **
1.09
1.08
Salary class in NHI registration (ref: bottom 1/3 class)
The middle 1/3 of the population
0.85
The top 1/3 of the population
1.08
Number of patients
Model significance (results from log-likelihood ratio tests)
**
19,127
χ2(103)=3,099.81**
Results from log-likelihood ratio tests for comparing the final model
with the other two models
19,127
χ2(102)=3,073.91**
χ2(1)=25.9**
-5-
19,127
χ2(67)=
3,067.7**
χ2(36)=32.1
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
Part 2: 6-month survival
Predictor
6-month
survival model selected as
final models in the paper
adjusted OR†
Diagnoses at PMV onset (excluding respiratory failure)
Septicemia
Other infectious and parasitic diseases
Neoplasms
Diabetes mellitus
Nutritional deficiencies
Fluid and electrolyte disorders
Other endocrine/nutritional/metabolic diseases & immunity disorders
Coagulation and hemorrhagic disorders
Other diseases of the blood and blood-forming organs
Mental illness
Diseases of the nervous system and sense organs
Hypertension
Heart valve disorders
Acute myocardial infarction and coronary atherosclerosis
Cardiac dysrhythmias
Other diseases of the heart
Cerebrovascular diseases
Other diseases of the circulatory system
Pneumonia
Chronic obstructive pulmonary disease and bronchiectasis
Asthma
Other diseases of the respiratory system
Gastrointestinal hemorrhage
Other diseases of the digestive system
Acute and unspecified renal failure
0.56 **
0.81 **
0.31 **
0.77 **
0.88
0.94
0.83 *
0.55 **
1.09
1.26 *
1.06
1.30 **
1.02
0.98
0.87
0.73 **
1.03
0.73 **
0.84 **
1.16 **
0.85
0.87 **
0.74 **
0.90 *
0.40 **
-6-
6-month
survival model that
excluded the year variable
adjusted OR†
0.56 **
0.81 **
0.31 **
0.77 **
0.88
0.94
0.82 **
0.55 **
1.09
1.26 *
1.06
1.31 **
1.01
0.99
0.87
0.74 **
1.03
0.74 **
0.84 **
1.15 **
0.85
0.87 **
0.73 **
0.90 *
0.40 **
6-month
survival model using
stepwise regression
adjusted OR†
0.57 **
0.81 **
0.31 **
0.77 **
0.82 **
0.53 **
1.24 *
1.07
1.31 **
0.88
0.74 **
0.71 **
0.83 **
0.85
0.86 **
0.73 **
0.88 **
0.39 **
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
Predictor
6-month
survival model selected as
final models in the paper
adjusted OR†
Urinary tract infections
Other diseases of the genitourinary system
Complications: pregnancy/childbirth/puerperium
Diseases of the skin and subcutaneous tissue
Diseases of the musculoskeletal system and connective tissue
Congenital anomalies
Spinal cord injury
Intracranial injury
Other injury and poisoning
Symptoms; signs; and ill-defined conditions and factors
Shock
Parkinson's disease
Heart failure
Alcoholic liver disease
Non-alcoholic liver disease
Multiple sclerosis/Other hereditary & degenerative nervous system
conditions
1.19
**
0.79
0.70
0.75
1.06
1.11
1.90
1.32
1.04
0.87
0.47
1.94
0.76
0.83
0.67
**
6-month
survival model that
excluded the year variable
adjusted OR†
**
**
**
**
**
**
**
1.10
Chronic renal failure
0.43 **
Disease history (Number of admissions for the disease in the previous year; excluding respiratory failure)
Septicemia
1.12 **
Other infectious and parasitic diseases
0.95
Neoplasms
0.89 **
Diabetes mellitus
0.94 **
Nutritional deficiencies
0.92
Fluid and electrolyte disorders
0.96
Other endocrine/nutritional/metabolic diseases & immunity disorders
1.00
Coagulation and hemorrhagic disorders
0.91
-7-
1.20 **
0.79 **
0.70
0.74 **
1.07
1.12
1.88 **
1.31 **
1.04
0.88
0.47 **
1.95 **
0.76 **
0.84
0.67 **
6-month
survival model using
stepwise regression
adjusted OR†
1.17 **
0.78 **
0.73 **
1.95 **
1.37 **
0.46 **
1.77 **
0.72 **
0.66 **
1.09
0.44 **
1.12 **
0.95
0.89 **
0.94 **
0.92
0.97
1.00
0.91
0.43 **
0.96
0.88 **
0.94 **
0.90
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
Predictor
6-month
survival model selected as
final models in the paper
adjusted OR†
Other diseases of the blood and blood-forming organs
Mental illness
Diseases of the nervous system and sense organs
Hypertension
Heart valve disorders
Acute myocardial infarction and coronary atherosclerosis
Cardiac dysrhythmias
Other diseases of the heart
Cerebrovascular diseases
Other diseases of the circulatory system
Pneumonia
Chronic obstructive pulmonary disease and bronchiectasis
Asthma
Other diseases of the respiratory system
Gastrointestinal hemorrhage
Other diseases of the digestive system
Acute and unspecified renal failure
Urinary tract infections
Other diseases of the genitourinary system
Complications: pregnancy/childbirth/puerperium
Diseases of the skin and subcutaneous tissue
Diseases of the musculoskeletal system and connective tissue
Congenital anomalies
Spinal cord injury
Intracranial injury
Other injury and poisoning
Symptoms; signs; and ill-defined conditions and factors
0.83
1.00
1.03
1.01
0.96
0.98
1.04
1.09
1.09
0.99
1.11
1.02
1.04
0.99
0.99
0.99
1.15
0.97
0.95
0.92
0.92
0.94
0.96
1.08
1.14
0.96
0.98
-8-
**
**
**
*
**
*
6-month
survival model that
excluded the year variable
adjusted OR†
0.83 **
1.00
1.03
1.01
0.96
0.98
1.04
1.09
1.09 **
0.99
1.11 **
1.02
1.03
0.99
0.99
0.99
1.15 *
0.98
0.95
0.90
0.91 **
0.94
0.95
1.08
1.15 *
0.96
0.97
6-month
survival model using
stepwise regression
adjusted OR†
0.83 **
0.97
1.11 *
1.09 **
1.12 **
1.14 *
0.94 *
0.91 **
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
Predictor
6-month
survival model selected as
final models in the paper
adjusted OR†
Shock
Parkinson's disease
Heart failure
Alcoholic liver disease
Non-alcoholic liver disease
Multiple sclerosis/Other hereditary & degenerative nervous system
conditions
Chronic renal failure
1.25
0.95
0.95
0.92
0.86
**
**
1.08
6-month
survival model that
excluded the year variable
adjusted OR†
6-month
survival model using
stepwise regression
adjusted OR†
1.25 **
0.95
0.95
0.92
0.86 **
1.27 **
1.08
1.11
0.85 **
0.88
**
0.88 **
0.87 **
0.84
**
0.84 **
0.86 **
35–44
0.64
**
0.65 **
0.64 **
45–54
0.60
**
0.61 **
0.62 **
55–64
0.52
**
0.52 **
0.53 **
65–74
0.36
**
0.36 **
0.37 **
75–84
0.27
**
0.27 **
0.28 **
≥85
0.21
**
0.21 **
0.22 **
1.06
**
Gender (ref: female)
Male
Age group (ref: 17–34)
PMV incidence year
continuous variable in the value range: [1998, 2002]
1.06 **
Branch of hospital location (ref: Taipei)
Northern region
0.94
Central region
1.14
Southern region
0.97
Kao-Ping region
0.88
-9-
0.94
**
*
1.14
0.95
**
1.15 **
0.98
0.99
0.88 *
0.89 *
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
6-month
survival model selected as
final models in the paper
adjusted OR†
Predictor
Eastern region
1.00
6-month
survival model that
excluded the year variable
adjusted OR†
6-month
survival model using
stepwise regression
adjusted OR†
1.01
1.00
Hospital type (ref: medical centre)
Regional hospital
0.89
**
0.89 **
0.90 **
Local hospital
0.86 **
0.86 **
0.87 **
Small city or town
1.04
1.04
1.03
Remote or rural area
0.98
0.99
0.98
NHI registration location (ref: big city)
Salary class in NHI registration (ref: bottom 1/3 class)
The middle 1/3 of the population
0.85
**
0.85 **
0.85 **
The top 1/3 of the population
1.12
*
1.13 **
1.12 *
Number of patients
Model significance (results from log-likelihood ratio tests)
19,127
χ2(103)=3,032.36**
Results from log-likelihood ratio tests for comparing the final model
with the other two models
- 10 -
19,127
19,127
χ2(102)=3,008.05**
χ2(63)=2,982.88**
χ2(1)=24.3**
χ2(40)=49.5
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
Part 3: 1-year survival
Predictor
1-year
survival model selected as
final models in the paper
adjusted OR†
Diagnoses at PMV onset (excluding respiratory failure)
Septicemia
Other infectious and parasitic diseases
Neoplasms
Diabetes mellitus
Nutritional deficiencies
Fluid and electrolyte disorders
Other endocrine/nutritional/metabolic diseases & immunity disorders
Coagulation and hemorrhagic disorders
Other diseases of the blood and blood-forming organs
Mental illness
Diseases of the nervous system and sense organs
Hypertension
Heart valve disorders
Acute myocardial infarction and coronary atherosclerosis
Cardiac dysrhythmias
Other diseases of the heart
Cerebrovascular diseases
Other diseases of the circulatory system
Pneumonia
Chronic obstructive pulmonary disease and bronchiectasis
Asthma
Other diseases of the respiratory system
Gastrointestinal hemorrhage
Other diseases of the digestive system
Acute and unspecified renal failure
0.60 **
0.80 **
0.30 **
0.72 **
0.84
0.97
0.79 **
0.61 *
0.98
1.20
1.04
1.41 **
1.18
1.10
0.91
0.76 *
1.00
0.80 *
0.86 **
1.10
0.95
0.89 *
0.76 **
0.99
0.48 **
- 11 -
1-year
survival model that
excluded the year variable
adjusted OR†
0.60 **
0.80 **
0.30 **
0.72 **
0.83
0.97
0.79 **
0.61 *
0.98
1.21
1.04
1.41 **
1.17
1.10
0.91
0.77 *
1.00
0.81 *
0.86 **
1.10
0.95
0.89 *
0.75 **
0.99
0.48 **
1-year
survival model using
stepwise regression
adjusted OR†
0.61 **
0.77 **
0.29 **
0.71 **
0.82
0.79 **
0.60 **
1.01
1.42 **
0.93
0.76 *
0.77 **
0.89 **
1.11 *
0.89 **
0.76 **
0.46 **
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
Predictor
1-year
survival model selected as
final models in the paper
adjusted OR†
Urinary tract infections
Other diseases of the genitourinary system
Complications: pregnancy/childbirth/puerperium
Diseases of the skin and subcutaneous tissue
Diseases of the musculoskeletal system and connective tissue
Congenital anomalies
Spinal cord injury
Intracranial injury
Other injury and poisoning
Symptoms; signs; and ill-defined conditions and factors
Shock
Parkinson's disease
Heart failure
Alcoholic liver disease
Non-alcoholic liver disease
Multiple sclerosis/Other hereditary & degenerative nervous system
conditions
1.14
**
0.75
0.66
0.75
1.13
1.26
1.72
1.30
1.14
0.82
0.55
1.82
0.79
0.83
0.72
**
1-year
survival model that
excluded the year variable
adjusted OR†
**
**
**
*
**
**
**
**
1.11
Chronic renal failure
0.41 **
Disease history (Number of admissions for the disease in the previous year; excluding respiratory failure)
Septicemia
1.08
Other infectious and parasitic diseases
0.96
Neoplasms
0.88 **
Diabetes mellitus
0.93 **
Nutritional deficiencies
0.85
Fluid and electrolyte disorders
1.06
Other endocrine/nutritional/metabolic diseases & immunity disorders
1.02
Coagulation and hemorrhagic disorders
1.00
- 12 -
1.15 **
0.75 **
0.66
0.74 **
1.14
1.27
1.71 **
1.29 **
1.14 *
0.82
0.55 **
1.82 **
0.79 **
0.83
0.72 **
1-year
survival model using
stepwise regression
adjusted OR†
0.75 **
0.74 **
1.11
1.26
1.64 **
1.29 **
1.12
0.54 **
1.79 **
0.78 **
0.69 **
1.10
1.12
0.41 **
0.40 **
1.08
0.96
0.88 **
0.93 **
0.85
1.07
1.02
1.00
0.88 **
0.93 **
0.88
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
Predictor
1-year
survival model selected as
final models in the paper
adjusted OR†
Other diseases of the blood and blood-forming organs
Mental illness
Diseases of the nervous system and sense organs
Hypertension
Heart valve disorders
Acute myocardial infarction and coronary atherosclerosis
Cardiac dysrhythmias
Other diseases of the heart
Cerebrovascular diseases
Other diseases of the circulatory system
Pneumonia
Chronic obstructive pulmonary disease and bronchiectasis
Asthma
Other diseases of the respiratory system
Gastrointestinal hemorrhage
Other diseases of the digestive system
Acute and unspecified renal failure
Urinary tract infections
Other diseases of the genitourinary system
Complications: pregnancy/childbirth/puerperium
Diseases of the skin and subcutaneous tissue
Diseases of the musculoskeletal system and connective tissue
Congenital anomalies
Spinal cord injury
Intracranial injury
Other injury and poisoning
Symptoms; signs; and ill-defined conditions and factors
0.78
1.00
1.05
1.00
0.94
0.96
1.04
1.03
1.08
0.99
1.08
1.01
1.07
1.00
0.99
0.98
0.97
0.94
0.96
0.84
0.92
0.92
1.00
0.97
1.08
0.98
0.96
- 13 -
**
**
**
*
*
*
1-year
survival model that
excluded the year variable
adjusted OR†
0.78 **
1.00
1.05
1.00
0.94
0.96
1.04
1.02
1.08 **
0.99
1.08 **
1.01
1.07
1.00
0.99
0.98
0.97
0.94 *
0.96
0.82
0.92 *
0.92 *
1.00
0.97
1.09
0.98
0.96
1-year
survival model using
stepwise regression
adjusted OR†
0.79 **
1.09 **
0.98
0.99
0.96
0.94
0.91 *
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
Predictor
1-year
survival model selected as
final models in the paper
adjusted OR†
Shock
Parkinson's disease
Heart failure
Alcoholic liver disease
Non-alcoholic liver disease
Multiple sclerosis/Other hereditary & degenerative nervous system
conditions
Chronic renal failure
1.18
0.99
0.91
0.86
0.89
*
*
*
1.02
1-year
survival model that
excluded the year variable
adjusted OR†
1.18 *
0.99
0.91 *
0.86
0.89 *
1-year
survival model using
stepwise regression
adjusted OR†
1.24 **
0.92 *
0.88 **
1.02
0.83
**
0.83 **
0.82 **
0.79
**
0.79 **
0.80 **
35–44
0.61
**
0.62 **
0.61 **
45–54
0.54
**
0.55 **
0.56 **
55–64
0.43
**
0.43 **
0.45 **
65–74
0.28
**
0.28 **
0.30 **
75–84
0.19
**
0.19 **
0.20 **
≥85
0.15
**
0.15 **
0.16 **
1.07
**
Gender (ref: female)
Male
Age group (ref: 17–34)
PMV incidence year
continuous variable in the value range: [1998, 2002]
1.07 **
Branch of hospital location (ref: Taipei)
Northern region
0.99
0.99
1.00
Central region
1.12
*
Southern region
0.87
*
0.88 *
0.88 *
Kao-Ping region
0.84
**
0.84 **
0.85 **
- 14 -
1.12
*
1.13 *
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
1-year
survival model selected as
final models in the paper
adjusted OR†
Predictor
Eastern region
0.87
1-year
survival model that
excluded the year variable
adjusted OR†
1-year
survival model using
stepwise regression
adjusted OR†
0.88
0.87
Hospital type (ref: medical centre)
Regional hospital
0.85
**
0.85 **
0.87 **
Local hospital
0.87
**
0.87 **
0.90 *
NHI registration location (ref: big city)
Small city or town
1.02
1.03
1.03
Remote or rural area
1.02
1.03
1.02
0.89 **
0.89 **
Salary class in NHI registration (ref: bottom 1/3 class)
**
The middle 1/3 of the population
0.89
The top 1/3 of the population
1.08
1.09
1.08
19,127
19,127
19,127
Number of patients
Model significance (results from log-likelihood ratio tests)
χ2(103)=2,939.46**
Results from log-likelihood ratio tests for comparing the final model
with the other two models
- 15 -
χ2(102)=2,914.93**
χ2(63)=2,875.31**
χ2(1)=24.5**
χ2(40)=64.1**
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
Part 4: 2-year survival
Predictor
2-year
survival model selected as
final models in the paper
adjusted OR†
Diagnoses at PMV onset (excluding respiratory failure)
Septicemia
Other infectious and parasitic diseases
Neoplasms
Diabetes mellitus
Nutritional deficiencies
Fluid and electrolyte disorders
Other endocrine/nutritional/metabolic diseases & immunity disorders
Coagulation and hemorrhagic disorders
Other diseases of the blood and blood-forming organs
Mental illness
Diseases of the nervous system and sense organs
Hypertension
Heart valve disorders
Acute myocardial infarction and coronary atherosclerosis
Cardiac dysrhythmias
Other diseases of the heart
Cerebrovascular diseases
Other diseases of the circulatory system
Pneumonia
Chronic obstructive pulmonary disease and bronchiectasis
Asthma
Other diseases of the respiratory system
Gastrointestinal hemorrhage
Other diseases of the digestive system
Acute and unspecified renal failure
0.63
0.82
0.31
0.73
0.71
0.96
0.72
0.74
0.95
1.19
1.07
1.39
1.17
1.23
0.97
0.82
0.99
0.94
0.88
1.10
1.00
0.92
0.79
0.99
0.56
- 16 -
**
**
**
**
*
**
**
**
**
*
**
2-year
survival model that
excluded the year variable
adjusted OR†
0.63 **
0.82 **
0.31 **
0.73 **
0.71 *
0.96
0.72 **
0.74
0.95
1.19
1.07
1.39 **
1.16
1.23 **
0.97
0.83
0.99
0.94
0.88 **
1.09
1.00
0.92
0.78 **
0.99
0.56 **
2-year
survival model using
stepwise regression
adjusted OR†
0.63 **
0.80 **
0.31 **
0.73 **
0.71 *
0.75 **
1.08
1.38 **
1.13
0.90 **
0.93
0.79 **
0.53 **
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
Predictor
2-year
survival model selected as
final models in the paper
adjusted OR†
Urinary tract infections
Other diseases of the genitourinary system
Complications: pregnancy/childbirth/puerperium
Diseases of the skin and subcutaneous tissue
Diseases of the musculoskeletal system and connective tissue
Congenital anomalies
Spinal cord injury
Intracranial injury
Other injury and poisoning
Symptoms; signs; and ill-defined conditions and factors
Shock
Parkinson's disease
Heart failure
Alcoholic liver disease
Non-alcoholic liver disease
Multiple sclerosis/Other hereditary & degenerative nervous system
conditions
1.12
*
0.78
0.54
0.77
1.17
1.30
1.74
1.34
1.30
0.91
0.63
1.32
0.77
0.81
0.84
**
2-year
survival model that
excluded the year variable
adjusted OR†
**
**
**
**
**
**
1.12
Chronic renal failure
0.43 **
Disease history (Number of admissions for the disease in the previous year; excluding respiratory failure)
Septicemia
1.05
Other infectious and parasitic diseases
0.94
Neoplasms
0.89 **
Diabetes mellitus
0.91 **
Nutritional deficiencies
0.80 *
Fluid and electrolyte disorders
1.05
Other endocrine/nutritional/metabolic diseases & immunity disorders
1.08
Coagulation and hemorrhagic disorders
0.86
- 17 -
1.12 *
0.78 **
0.55
0.76 **
1.17
1.31
1.74 **
1.33 **
1.30 **
0.92
0.63 **
1.32
0.77 **
0.82
0.84
2-year
survival model using
stepwise regression
adjusted OR†
0.79 **
0.75 **
1.16
1.33
1.79 **
1.33 **
1.29 **
0.64 **
0.74 **
1.11
1.11
0.43 **
0.42 **
1.05
0.94
0.89 **
0.91 **
0.80 *
1.06
1.08
0.86
0.89 **
0.90 **
0.82 *
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
Predictor
2-year
survival model selected as
final models in the paper
adjusted OR†
0.80 **
0.99
0.99
0.96
1.00
0.95
0.99
1.02
1.06 *
0.98
1.04
1.00
1.01
1.03
1.00
1.00
0.98
0.97
0.95
1.06
0.94
0.92
1.05
1.04
1.03
0.98
0.98
Other diseases of the blood and blood-forming organs
Mental illness
Diseases of the nervous system and sense organs
Hypertension
Heart valve disorders
Acute myocardial infarction and coronary atherosclerosis
Cardiac dysrhythmias
Other diseases of the heart
Cerebrovascular diseases
Other diseases of the circulatory system
Pneumonia
Chronic obstructive pulmonary disease and bronchiectasis
Asthma
Other diseases of the respiratory system
Gastrointestinal hemorrhage
Other diseases of the digestive system
Acute and unspecified renal failure
Urinary tract infections
Other diseases of the genitourinary system
Complications: pregnancy/childbirth/puerperium
Diseases of the skin and subcutaneous tissue
Diseases of the musculoskeletal system and connective tissue
Congenital anomalies
Spinal cord injury
Intracranial injury
Other injury and poisoning
Symptoms; signs; and ill-defined conditions and factors
- 18 -
2-year
survival model that
excluded the year variable
adjusted OR†
0.81 **
0.99
0.99
0.97
1.00
0.95
0.99
1.02
1.06 *
0.98
1.04
1.00
1.01
1.03
1.00
1.00
0.99
0.97
0.95
1.04
0.94
0.92
1.04
1.03
1.03
0.98
0.98
2-year
survival model using
stepwise regression
adjusted OR†
0.79 **
0.97
0.98
1.01
0.98
0.94
0.97
0.92 *
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
Predictor
2-year
survival model selected as
final models in the paper
adjusted OR†
Shock
Parkinson's disease
Heart failure
Alcoholic liver disease
Non-alcoholic liver disease
Multiple sclerosis/Other hereditary & degenerative nervous system
conditions
Chronic renal failure
1.12
1.01
0.91
0.72
0.92
*
*
0.97
2-year
survival model that
excluded the year variable
adjusted OR†
2-year
survival model using
stepwise regression
adjusted OR†
1.12
1.01
0.92
0.72 *
0.92
0.97
**
0.78 **
0.77 **
0.78 **
0.78 **
0.78 **
0.78
Gender (ref: female)
Male
Age group (ref: 17–34)
35–44
0.65
**
0.66 **
0.64 **
45–54
0.55
**
0.56 **
0.57 **
55–64
0.39
**
0.39 **
0.41 **
65–74
0.25
**
0.25 **
0.27 **
75–84
0.16
**
0.16 **
0.18 **
≥85
0.11
**
0.11 **
0.12 **
1.06
**
PMV incidence year
continuous variable in the value range: [1998, 2002]
1.06 **
Branch of hospital location (ref: Taipei)
Northern region
0.99
0.99
0.98
Central region
1.13
*
Southern region
0.86
*
0.86 *
0.86 *
Kao-Ping region
0.82
**
0.83 **
0.82 **
- 19 -
1.13
*
1.13 *
PMV file 2 to reviewers (ORs for all variables for 3 sets of models)
2-year
survival model selected as
final models in the paper
adjusted OR†
Predictor
Eastern region
0.90
2-year
survival model that
excluded the year variable
adjusted OR†
2-year
survival model using
stepwise regression
adjusted OR†
0.91
0.89
Hospital type (ref: medical centre)
Regional hospital
0.87
**
0.87 **
0.89 **
Local hospital
0.85
**
0.85 **
0.88 *
NHI registration location (ref: big city)
Small city or town
1.04
1.04
1.04
Remote or rural area
1.04
1.05
1.04
0.89 **
0.87 **
Salary class in NHI registration (ref: bottom 1/3 class)
**
The middle 1/3 of the population
0.88
The top 1/3 of the population
1.07
1.08
1.07
19,127
19,127
19,127
Number of patients
Model significance (results from log-likelihood ratio tests)
χ2(103)=2,652.06**
Results from log-likelihood ratio tests for comparing the final model
with the other two models
PMV: prolonged mechanical ventilation
OR: odds-ratio.
CI: confidence interval.
*
p<0.05; ** p<0.01.
†
The OR was adjusted for all other covariates.
- 20 -
χ2(102)=2,633.87**
χ2(55)=2,570.22**
χ2(1)=18.2**
χ2(48)=81.8**