‫بسمه تعالي‬
‫■ مشخصات فردي‪:‬‬
‫نااااانام منااااانام ااااانن‬
‫آ رينممدركمتحصيل ‪Ph.D.‬‬
‫رشتهمتحصيل مشامي د روييم‬
‫مرتبهمعلم‬
‫د روسازي) م‬
‫ستن‬
‫مسععععععام‬
‫معععععامي مممممممم‬
‫(د نشگاه علوم پزشكي مازنمر ن‪-‬د نشكمه‬
‫■ سو بق تحصالي ‪:‬‬
‫م‬
‫درجه‬
‫تحصالي‬
‫‪1‬‬
‫كتر يم‬
‫حرفهم ي‬
‫‪2‬‬
‫‪Ph.D.‬م‬
‫‪3‬‬
‫رشته تحصالي‬
‫ر سنزيم‬
‫شيم م‬
‫ر ي م‬
‫رهمتكميل م‬
‫تحقيقنت‬
‫د نشگاه‬
‫نشگنهمعل ام‬
‫پزشك مكرمننم‬
‫نشگنهمعل ام‬
‫پزشك متهر نم‬
‫نشگنهمآلبرتن‬
‫مکان‬
‫جغر فاايي‬
‫سال‬
‫شروع‬
‫سال‬
‫پايان‬
‫ير نم‬
‫‪3173‬م‬
‫‪3131‬‬
‫ير نم‬
‫‪3131‬م‬
‫‪3133‬م‬
‫‪3131‬‬
‫‪3133‬‬
‫كننن‬
‫م‬
‫م‬
‫م‬
‫م‬
‫■ سو بق پژوهشي ‪:‬‬
‫لف‪ -‬مقاالت منتشر شمه فارسي‬
‫‪ )1‬فر مدي معليرضن‪ ،‬محقيقت م مپ پك‪ ،‬م م مامي سعام‪ ،‬م ممصحف ممحمدم‬
‫حسن‪،‬سنتزم مبررس مفعنليتمضدمميكر ب مپيپر زينيلمكين ل نمهنيم‬
‫جديد‪.‬ممجلهم نشگنهمعل امپزشك مكرمنن‪ ،‬م م رهمپنجم‪،‬مشمنرهم‪،1‬مم‬
‫ص‪،311-311‬مم‬
‫‪3133‬مم‬
‫م‬
‫‪ )2‬م منم مسعيد‪ ،‬مسنتز ممشتقنت مجديد م‪-2‬متيل‪-1-‬ترينز ليلم‬
‫كر منن ن م كسيم م تر مبه معن ن متركيبنت مبنلق ه مضد مقنرچ‪ .‬ممجلهم‬
‫نشگنه معل ا مپزشك ممنزندر ن‪ ،‬م م ره مشننز هم‪ ،‬مشمنره م‪،11‬م‬
‫م مشهري رم‪،3131‬مصفحنتم‪.37-22‬م‬
‫مر‬
‫‪ )3‬م منم مسعيد‪ ،‬سنتز متركيبنت مجديد ممشتق م‪ 1‬م‪ -2،‬ي مآريل‪-2-‬‬
‫تينز لين‪-2-‬تي ن مبن م ثر مبنلق ه ممهنر مكننده م‪ ،COX-2‬ممجلهم‬
‫نشگنه معل ا مپزشك ممنزندر ن‪ ،‬م ره مشننز هم‪ ،‬مشمنره م‪ ،17‬مبهمنم‬
‫م سفندم‪،3131‬مصفحنتم‪71-73‬م‪.‬‬
‫‪1‬‬
‫نگلاسي‬
‫ مقاالت منتشر شمه‬-‫ب‬
1) Foroumadi, A. ; Emami, S.; Davood, A.; Moshafi, M. H.; Sharifian, A.; Tabatabaiee, M.;
Tarhimi Farimani, H.; Sepehri, G.; Shafiee, A. Synthesis and in-vitro antibacterial activities of
N-substituted piperazinyl quinolones. Pharmaceutical Sciences. 1997, 3, 559
2) Foroumadi, A. ; Emami, S. Haghighat, P.; Moshafi, M. H. Synthesis and in-vitro antibacterial
activity of new N-substituted piperazinyl quinolones. Pharm. Pharmacol. Commun. 1999, 5,
591–594.
3) Emami, S.; Shafiee, A. Stereoselective Syntheses of (E)- and (Z)-2,3-Dihydro-3-(1,2,4triazolyl)-4H-1-benzopyran-4-one Oxime Ethers. Heterocycles, 2001, 55(11), 2059–2074.
4) Foroumadi, A.; Davood, A.; Mirzaei, M.; Emami, S.; Moshafi, M. H. Synthesis and
antibacterial activity of some novel N-substituted piperazinyl quinolones. Boll. Chim. Farm.
2001, 140(6), 411–416.
5) Emami, S.; Falahati, M.; Banifatemi, A.; Moshiri, K.; Shafiee, A. Stereoselective synthesis
and in vitro antifungal evaluation of (E)- and (Z)-imidazolylchromanone oxime ethers. Arch.
Pharm. Pharm. Med. Chem. 2002, 335(7), 318–324.
6) Foroumadi, A. ; Soltani, F.; Emami, S.; Davood, A. Antituberculosis agents. III. In vitro
evaluation of antimycobacterial activity and cytotoxicity of some N-substituted piperazinyl
quinolones. Boll. Chim. Farm. 2002, 141(3), 247–249.
7) Foroumadi, A.; Mirzaei, M.; Emami, S.; Salari, P.; Ghaffari, F.; Amini, M.; Shafiee, A.
Synthesis and antifungal activity of some new 1,2,4-triazolo [3,4-b][1,3,4]thiadiazines. Daru,
2002, 10(1), 34–37.
8) Foroumadi, A. ; Asadipour, A.; Mirzaei, M. ; Karimi, J. ; Emami, S. Antituberculosis agents.
V. Synthesis, evaluation of in vitro antituberculosis activity and cytotoxicity of some 2-(5nitro-2-furyl)-1,3,4-thiadiazole derivatives. Il Farmaco, 2002, 57, 765–769.
9) Foroumadi, A. ; Ashraf-Askari, R.; Moshafi, M.H.; Emami, S.; Zeynali, A. Synthesis and in
vitro antibacterial activity of N-[5-(5-nitro-2-furyl)-1,3,4-thiadiazol-2-yl]piperazinyl
quinolone derivatives. Pharmazie, 2003, 58(6), 432–433.
10) Emami, S. ; Falahati, M.; Banifatemi, A.; Amanlou, M.; Shafiee, A. (E)- and (Z)-1,2,4triazolylchromanone oxime ethers as conformationally constrained antifungals. Bioorg. Med.
Chem., 2004, 12 (15), 3971–3976.
11) Emami, S. ; Falahati, M.; Banifatemi, A.; Shafiee, A. Stereoselective synthesis and antifungal
activity of (Z)-trans-3-azolyl-2-methylchromanone oxime ethers. Bioorg. Med. Chem., 2004,
12 (22), 5881–5889.
12) Emami, S.; Shafiee, A. Synthesis, stereochemical and conformational properties of trans-2,3dihydro-2-methyl-3-(1,2,4-triazolyl)-4H-1-benzopyran-4-one oxime ethers. Tetrahedron,
2005, 61, 2649–2654.
2
13) Emami, S.; Foroumadi, A.; Asadipour, A.; Toyserkani, A. Synthesis of 1-(furan-2-yl)-2-(1Himidazol-1-yl)ethanone O-benzyloxime as a furan analog of oxiconazole. Chemistry: An
Indian Journal, 2005, 1(12), 749–751.
14) Emami, S.; Falahati, M.; Banifatemi, A.; Roudaki, M. M. Synthesis and antifungal activity of
some new (Z)-trans-2-methyl-3-(1,2,4-triazol-4-yl) chromanone oxime derivatives. Chemistry:
An Indian Journal, 2005, 1(11), 713–717.
15) Foroumadi, A.; Emami, S.; Rezvani, N.; Shafiee, A.; Asadipour, A. Synthesis of certain
diarylsulfonylurea derivatives as new potential antitumor agents. Chemistry: An Indian
Journal, 2005, 1(12) 745–748.
16) Foroumadi, A.; Emami, S.; Hassanzadeh, A.; Rajaee, M.; Sokhanvar, K.; Moshafi, M. H.;
Shafiee, A. Synthesis and antibacterial activity of N-(5-benzylthio-1,3,4-thiadiazol-2-yl) and
N-(5-benzylsulfonyl-1,3,4-thiadiazol-2-yl)piperazinyl quinolone derivatives. Bioorg. Med.
Chem. Lett., 2005, 15, 4488–4492.
17) Foroumadi, A.; Emami, S.; Mehni, M.; Moshafi, M. H.; Shafiee, A. Synthesis and
antibacterial activity of N-[2-(5-bromothiophen-2-yl)-2-oxoethyl] and N-[(2-5bromothiophen-2-yl)-2-oximinoethyl] derivatives of piperazinyl quinolones. Bioorg. Med.
Chem. Lett., 2005, 15, 4536–4539.
18) Emami, S.; Foroumadi, A. Synthesis and antifungal evaluation of allyl containing derivatives
of 5-(5-nitrofuran-2-yl)-1,3,4-thiadiazole. Chemistry: An Indian Journal, 2005, 2(1), 10–13.
19) Emami, S. Synthesis of 2,3-dihydro-3-hydroxymethyl-3-(4H-1,2,4-triazol-4-yl)- 4H-1benzopyran-4-ones. Chemistry: An Indian Journal, 2005, 2(1), 14–16.
20) Foroumadi, A.; Emami, S.; Pournourmohammadi, S.; Kharazmi, A.; Shafiee, A. Synthesis
and in vitro leishmanicidal activity of 2-(1-methyl-5-nitro-1H-imidazol-2-yl)-5-substituted1,3,4-thiadiazole derivatives. Eur. J. Med. Chem., 2005, 40, 1346–1350.
21) Emami, S.; Shafiee, A.; Foroumadi, A. Quinolones: Recent Structural and Clinical
Developments. Iranian Journal of Pharmaceutical Research, 2005, 3, 123–136.
22) Emami, S.; Kebriaeezadeh, A.; Zamani. M. J.; Shafiee, A. Azolylchromans as a novel
scaffold for anticonvulsant activity. Bioorg. Med. Chem. Lett., 2006, 16, 1803–1806.
23) Foroumadi, A.; Oboudiat, M.; Emami, S.; Karimollah, A.; Saghaee, L. Moshafi, M. H.;
Shafiee, A. Synthesis and antibacterial activity of N-[2-[5-(methylthio)thiophen-2-yl]-2oxoethyl] and N-[2-[5-(methylthio)thiophen-2-yl]-2-(oxyimino)ethyl] piperazinylquinolone
derivatives. Bioorg. Med. Chem., 2006, 14 (10), 3421–3427.
24) Emami, S.; Shafiee, A.; Foroumadi, A. Structural features of new quinolones and relationship
to antibacterial activity against Gram-positive bacteria. Mini-Rev. Med. Chem., 2006, 6, 375–
386.
3
25) Emami, S.; Foroumadi, A. Synthesis of 4-(4-methylsulfonylphenyl)-3-phenyl-2(3H)-thiazole
thione derivatives as new potential COX-2 inhibitors. Chinese. J. Chem.2006, 24 (6), 791–
794.
26) Foroumadi, A.; Ghodsi, S.; Emami, S.; Najjari, S.; Samadi, N.; Faramarzi, M. A.;
Beikmohammadi, L.; Shirazi, F. H.; Shafiee, A. Synthesis and antibacterial activity of new
fluoroquinolones containing a substituted N-(phenethyl)piperazine moiety. Bioorg. Med.
Chem. Lett., 2006, 16, 3499–3503.
27) Foroumadi, A.; Mansouri, S.; Emami, S.; Mirzaei, J.; Sorkhi, M.; Saeid-Adeli, N.; Shafiee, A.
Synthesis and antibacterial activity of nitroaryl thiadiazole-levofloxacin hybrids. Arch. Pharm.
2006, 339 (11), 621–624.
28) Emami, S.; Hosseinimehr, S. J.; Taghdisi, S. M.; Akhlaghpoor, S. Kojic acid and its
manganese and zinc complexes as potential radioprotective agents. Bioorg. Med. Chem. Lett.,
2007, 17 (1, January), 45–48.
29) Foroumadi, A.; Mohammadhosseini, N.; Emami, S.; Letafat, B.; Faramarzi, M. A.; Samadi,
N.; Shafiee, A. Synthesis and antibacterial activity of new 7-piperazinylquinolones containing
functionalized 2-(furan-3-yl)ethyl moiety. Arch. Pharm. 2007, 340 (1, January), 47–52.
30) Foroumadi, A.; Firoozpour, L.; Emami, S.; Mansouri, S.; Ebrahimabadi, A. H.; Asadipour,
A.; Amini, M.; Saeid-Adeli, N.; Shafiee, A. Synthesis and Antibacterial Activity of N-[5(chlorobenzylthio)-1,3,4-thiadiazol-2-yl] piperazinyl quinolone derivatives. Arch. Pharm. Res.
2007, 30 (No 2, Feb), 138–145.
31) Rajabalian, S.; Foroumadi, A.; Shafiee, A.; Emami, S. Functionalized N-(2oxyiminoethyl)piperazinyl quinolones as new cytotoxic agents. J. Pharm. Pharmaceut. Sci.
2007, 10 (No. 2, June), 153–158.
32) Emami, S.; Kumar, P.; Yang, J.; Kresolic, Z.; Paproski, R.; Cass, C.; McEwan, A. J. B.;
Wiebe, L. I. Synthesis, Transportability and Hypoxia-selective Binding of 1--D-(5-Deoxy-5Fluororibofuranosyl)-2-Nitroimidazole (-5-FAZR), a Configurational Isomer of the Clinical
Hypoxia Marker, FAZA. J. Pharm. Pharmaceut. Sci. 2007, 10 (No. 2, June), 235–243.
33) Emami, S.; Foroumadi, A. Theoretical study on Z/E selectivity in the oximation of αhaloacetophenones. Asian J. Chem. 2007, 19 (No. 6), 4727–4732.
34) Foroumadi, A.; Firoozpour, L.; Nematollahi, N.; Ebrahimabadi, A. H.; Emami, S.; Moshafi,
M. H.; Asadipour, A.; Shafiee, A. Synthesis of new fluoroquinolones containing a N-[5(fluorobenzylthio)-1,3,4-thiadiazol-2-yl]piperazine moiety. Asian J. Chem. 2007, 19 (No. 6),
4547–4552.
35) Letafat, B.; Emami, S.; Mohammadhosseini, N.; Faramarzi, M. A.; Samadi, N.; Shafiee, A.;
Foroumadi, A. Synthesis and antibacterial activity of new N-[2-(thiophen-3-yl)ethyl]
piperazinyl quinolones. Chem. Pharm. Bull. 2007, 55 (No. 6, June), 894–898.
4
36) Foroumadi, A.; Emami, S.; Mansouri, S.; Javidnia, A.; Saeid-Adeli, N.; Shirazi, F. H.;
Shafiee, A. Synthesis and antibacterial activity of levofloxacin derivatives with certain bulky
residues on piperazine ring. Eur. J. Med. Chem. 2007, 42 (No. 7, July), 985–992.
37) Foroumadi, A.; Samzadeh-Kermani, A.; Emami, S.; Dehghan, G.; Sorkhi, M.; Arabsorkhi, F.;
Heidari, M. R.; Abdollahi, M.; Shafiee, A.; Synthesis and antioxidant properties of some 3benzylidene-7-alkoxychroman-4-ones. Bioorg. Med. Chem. Lett. 2007, 17 (No. , Dec.), 6764–
6769.
38) Hosseinimehr, S. J.; Emami, S.; Taghdisi, S. M.; Akhlaghpoor, S. 5,7-Dihydroxychromone2-carboxylic acid and its transition-metal (Mn and Zn) chelates as non-thiol radioprotective
agents. Eur. J. Med. Chem. 2008, 43 (No. 3, March), 557–561.
39) Emami, S.; Foroumadi, A.; Faramarzi, M. A.; Samadi, N. Synthesis and antibacterial activity
of quinolone-based compounds containing a coumarin moiety. Arch. Pharm. Chem. Life Sci.
2008, 341, 42–48.
40) Emami, S.; Foroumadi, A.; Falahati, M.; Lotfali, E.; Rajabalian, S.; Ebrahimi, S.-A.; Farahyar,
S.; Shafiee, A. 2-Hydroxyphenacyl azoles and related azolium derivatives as antifungal
agents. Bioorg. Med. Chem. Lett. 2008, 18, 141–146.
41) Kebriaeezadeh, A.; Emami, S.*; Ebrahimi, M.; Sharifzadeh, M.; Khorasani, R.; Shafiee, A.
Anticonvulsant and antiepileptogenic effects of azolylchromanones on lithium–pilocarpine
induced seizures and pentylenetetrazole-kindling model of epilepsy. Biomed. Pharmacother.
2008, 62 (No. 4, April-May), 208–211.
42) Behrouzi-Fardmoghadam, M.; Poorrajab, F.; Ardestani, S. K.; Emami, S.; Shafiee, A.;
Foroumadi, A. Synthesis and in vitro anti-leishmanial activity of 1-[5-(5-nitro-2-furyl)-1,3,4thiadiazol-2-yl]- and 1-[5-(5-nitro-2-thienyl)-1,3,4-thiadiazol-2-yl]-4-aroylpiperazines.
Bioorg. Med. Chem. 2008, 16, (Issue 8, 15 April) 4509–4515.
43) Foroumadi, A.; Rineh, A.; Emami, S.; Siavoshi, F.; Massarrat, S.; Safari, F.; Rajabalian, S.;
Falahati, M.; Lotfali, E.; Shafiee, A. Synthesis and anti-Helicobacter pylori activity of 5(nitroaryl)-1,3,4-thiadiazoles with certain sulfur containing alkyl side chain. Bioorg. Med.
Chem. Lett. 2008, 18 (Issue 11, 1 June), 3315–3320.
44) Kumar, P.; Emami , S.; McEwan, A. J. B.; Wiebe, L. I. Stereospecific deuteration of furanosyl azomycin nucleosides; a model reaction for tritium radiolabeling. Bioorg. Med.
Chem. Lett. 2008, 18 (Issue 11, 1 June), 3256–3260.
45) Mirzaie, J.; Siavoshi, F.; Emami, S.; Safari, F.; Khoshayand, M. R.; Shafiee, A.; Foroumadi,
A. Synthesis and in vitro anti-Helicobacter pylori activity of N-[5-(5-nitro-2-heteroaryl)-1,3,4thiadiazol-2-yl]thiomorpholines and related compounds. Eur. J. Med. Chem. 2008, 43, 1575–
1580.
5
46) Letafat, B.; Emami, S.; Aliabadi, A.; Mohammadhosseini, N.; Moshafi, M. H.; Asadipour, A.;
Shafiee, A.; Foroumadi, A.; Synthesis and in-vitro antibacterial activity of 5-substituted-1methyl-4-nitro-1H-imidazoles. Arch. Pharm. Chem. Life Sci. 2008, 341, 497–501.
47) Shafiee, A.; Haddad Zahmatkesh, M.; Mohammadhosseini, N.; Khalafy, J.; Emami, S.;
Moshafi, MH.; Sorkhi, M.; Foroumadi, A. Synthesis and in-vitro antibacterial activity of Npiperazinyl quinolone derivatives with 5-chloro-2-thienyl group. Daru, 2008, 16 (No. 3), 189–
195.
48) Foroumadi, A.; Safavi, M.; Emami, S.; Siavoshi, F.; Najjari, S.; Safari, F.; Shafiee, A.
Structure-activity relationship study of a series of N-substituted piperazinyl-fluoroquinolones
as anti-Helicobacter pylori agents. Medicinal Chemistry, 2008, 4 (No. 5, September), 498–
502.
49) Mohammadhosseini, N.; Letafat, B.; Siavoshi, F.; Emami, S.; Safari, F.; Shafiee, A.;
Foroumadi, A. Synthesis and in vitro anti-Helicobacter pylori activity of 2[(chlorobenzyl)thio]-5-(5-nitro-2-furyl)-1,3,4-thiadiazoles. Med. Chem. Res., 2008, 17 (No. 9,
Dec.), 578–586.
50) Foroumadi, A.; Emami, S.; Rajabalian, S.; Badinloo, M.; Mohammadhosseini, N.; Shafiee,
A. N-Substituted piperazinyl quinolones as potential cytotoxic agents: Structure–activity
relationships study. Biomed. Pharmacother., 2009, 63 (No. 3, March.), 216–220.
51) Jazayeri, S.; Moshafi, M. H.; Firoozpour, L.; Emami, S.; Rajabalian, S.; Haddad , M.;
Pahlavanzadeh, F.; Esnaashari, M.; Shafiee, A.; Foroumadi; A. Synthesis and antibacterial
activity of nitroaryl thiadiazole-gatifloxacin hybrids. Eur. J. Med. Chem. 2009, 44 (No. 3),
1205–1209.
52) Poorrajab, F.; Ardestani, S. K.; Foroumadi, A.; Emami, S.; Kariminia, A.; BehrouziFardmoghadam, M.; Shafiee, A. Selective leishmanicidal effect of 1,3,4-thiadiazole
derivatives and possible mechanism of action against Leishmania species. Exp. Parasitol.
2009, 121 (No. 4, April), 323–330.
53) Emami, S.; Behdad, M.; Foroumadi, A.; Falahati, M.; Lotfali, E.; Sharifynia, S. Design of
conformationally constrained azole antifungals: Efficient synthesis and antifungal activity of
trans-3-imidazolylflavanones. Chem. Biol. Drug Des. 2009, 73 (No. 4, April), 388–395.
54) Poorrajab, F.; Ardestani, S. K.; Emami, S.; Behrouzi-Fardmoghadam, M.; Shafiee, A.;
Foroumadi, A. Nitroimidazolyl-1,3,4-thiadiazole-based anti-leishmanial agents: Synthesis and
in vitro biological evaluation. Eur. J. Med. Chem. 2009, 44 (No. 4, April), 1758–1762.
55) Kumar, P.; Emami, S.; McEwan, A. J.B.; Wiebe, L. I. Development of an Economical, Single
Step Synthesis of FAZA, a Clinical Hypoxia Marker, and Potential Synthons to Prepare its
Positional Analogs. Letters in Drug Design & Discovery, 2009, 6 (No. 1, January), 82–85.
6
56) Kumar, P.; Emami, S.; Kresolek, Z.; Yang, J.; McEwan, A. J. B.; Wiebe, L. I.. Synthesis and
hypoxia selective radiosensitization potential of β-2-FAZA and β-3-FAZL: Fluorinated
azomycin β-nucleosides. Med. Chem., 2009, 5 (No. 2, March), 118–29.
57) Hosseinimehr, S. J.; Emami, S.; Zakaryaee, V.; Ahmadi, A.; Moslemi, D. Radioprotective
effects of kojic acid against mortality induced by gamma irradiation in mice. Saudi Med. J.,
2009, 30 (No. 4), 490–493.
58) Shafiee, A.; Emami, S.; Ghodsi, S.; Najjari, S.; Sorkhi, M.; Samadi, N.; Faramarzi, M.A.;
Foroumadi, A. Synthesis and antibacterial activity of N-[2-(2-naphthyl)ethyl]piperazinyl
quinolones. J. Iran. Chem. Soc. 2009, 6 (No. 2, June), 325–332.
59) Emami, S.; Foroumadi, A.; Samadi, N.; Faramarzi, M. A.; Rajabalian, S. Conformationally
constrained analogs of N-substituted piperazinylquinolones: Synthesis and antibacterial
activity of N-(2,3-dihydro-4-hydroxyimino-4H-1-benzopyran-3-yl)-piperazinylquinolones.
Arch. Pharm. Chem. Life Sci. 2009, 342 (No. 7, July), 405–411.
60) Foroumadi, A.; Sedaghat, S.; Emami, S.; Yazdanian, M.; Moshafi, M. H.; Safavi, M.;
Sakhteman, A.; Firoozpour, L.; Vosooghi, M.; Shafiee, A. Synthesis and Structure-activity
Relationship Study of 2-Substituted- 5-(5-nitro-2-thienyl)-1,3,4-thiadiazoles as AntiHelicobacter pylori Agents. Letters in Drug Design & Discovery, 2009, 6 (No. 6, September),
468–474.
61) Emami, S.; Foroumadi, A. 3-Imidazolyl substituted flavans as potential antifungal agents:
Synthesis, stereochemical properties and antifungal activity. Arch. Pharm. Chem. Life Sci.
2009, 342 (No. 9, September), 541–545.
62) Bolouri, F.; Moghadami Tabrizi, N.; Davari Tanha, F.; Niroomand, N.; Azmoodeh, A.;
Emami, S.; Falahati, M.; Sharifynia, S.; Safavi, M.; Shasiee, A.; Foroumadi, A. Effectiveness
of fluconazole for suppressive maintenance therapy in patients with RVVC: a randomized
placebo-controlled study. Iranian Journal of Pharmaceutical Research, 2009, 8 (No. 4,
Autumn), 307–313.
63) Alireza Foroumadi, Maedeh Sorkhi, Mohammad Hassan Moshafi, Maliheh Safavi, Ardeshir
Rineh, Farideh Siavoshi, Abbas Shafiee, Saeed Emami*. 2-Substituted-5-nitroheterocycles:
In vitro anti-Helicobacter pylori activity and structure-activity relationship study. Med. Chem.,
2009, 5 (No. 6, Nov.), 529–534.
64) Zohreh Nazarian, Saeed Emami, Samaneh Heydari, Sussan K. Ardestani, Maryam Nakhjiri,
Fatemeh Poorrajab, Abbas Shafiee, Alireza Foroumadi, Novel antileishmanial chalconoids:
synthesis and biological activity of 1- or 3-(6-chloro-2H-chromen-3-yl)propen-1-ones. Eur. J.
Med. Chem. 2010, 45 (No. 4, April), 1424–1429.
65) Maliheh Safavi, Alireza Foroumadi, Maryam Nakhjiri, Mohammad Abdollahi, Abbas Shafiee,
Hoda Ilkhani, Mohammad Reza Ganjali, Seyed Jalal Hosseinimehr, Saeed Emami *.
7
Complexes of 2-hydroxyacetophenone semicarbazones: A novel series of superoxide
dismutase mimetics. Bioorg. Med. Chem. Lett. 2010, 20 (No. 10, 15 May), 3070–3073.
66) Alireza Foroumadi, Saeed Emami, Maedeh Sorkhi, Maryam Nakhjiri, Zohreh Nazarian,
Samaneh Heydari, Sussan K. Ardestani, Fatemeh Poorrajab, Abbas Shafiee, Chromene-based
synthetic chalcones as potent antileishmanial agents: synthesis and biological activity. Chem.
Biol. Drug Des. 2010, 75 (No. 6, June), 590–596.
67) Majid Mahmoodi, Alireza Aliabadi, Saeed Emami, Maliheh Safavi, Saeed Rajabalian,
Mohammad-Ali Mohagheghi, Ahad Khoshzaban, Alireza Samzadeh-Kermani, Navid Lamei,
Abbas Shafiee, Alireza Foroumadi, Synthesis and in vitro cytotoxicity of poly-functionalized
4-(2-arylthiazol-4-yl)-4H-chromenes. Arch. Pharm. Chem. Life Sci. 2010, 343 (No.,), 411–
416.
68) Navid Lamei, Alireza Foroumadi, Saeed Emami , Mohsen Amini, Abbas Shafiee,
Heterocycle-bridged and Conformationally Constrained Retinoids: Synthesis of 4-(7,8,9,10Tetrahydro-7,7,10,10-tetramethyl-4H-benzo[6,7]chromeno-[4,3-d]thiazole-2-yl)benzoic Acid.
Chinese Journal of Chemistry, 2010, 28 (No. 10, October) 1951–1956.
69) Alireza Aliabadi, Fazel Shamsa, Seyed Nasser Ostad, Saeed Emami, Abbas Shafiee, Jamshid
Davoodi, Alireza Foroumadi, Synthesis and biological evaluation of 2-phenylthiazole-4carboxamide derivatives as anticancer agents. Eur. J. Med. Chem. 2010, 45 (No. 11,
November), 5384–5389.
70) Babak Heidary Alizadeh, Alireza Foroumadi, Saeed Emami, Mehdi Khoobi, Fatemeh Panah,
Sussan K. Ardestani, Abbas Shafiee, Isochaihulactone analogues: Synthesis and antiproliferative activity of novel dibenzylbutyrolactones. Eur. J. Med. Chem. 2010, 45 (No. 12,
December) Pages 5979–5984.
71) Saeed Emami, Abbas Kebriaeezadeh, Nematollah Ahangar, Reza Khorasani,
Imidazolylchromanone oxime ethers as potential anticonvulsant agents: anticonvulsive
evaluation in PTZ-kindling model of epilepsy and SAR study. Bioorg. Med. Chem. Lett. 2011,
21 (No. 2, 15 January), 655–659.
72) Eskandar Alipour, Saeed Emami, Azadeh Yahya-Meymandi, Maryam Nakhjiri, Farnaz
Johari, Sussan K. Ardestani, Fatemeh Poorrajab, Maryam Hosseini, Abbas Shafiee, Alireza
Foroumadi, Synthesis and antileishmanial activity of 5-(5-nitroaryl)-2-substituted-thio-1,3,4thiadiazoles. J. Enzyme Inhib. Med. Chem. 2011, 26 (No. 1, February), 123–128.
73) Mohammad Hassan Moshafi, Azadeh Yahya-Meymandi, Seyed Esmaeil Sadat-Ebrahimi,
Saeed Emami, Maryam Nakhjiri, Farideh Siavoshi, Maryam Omrani, Mohsen Vosooghi,
Eskandar Alipour, Abbas Shafiee, Alireza Foroumadi, Synthesis and biological activity of 5nitrofuran-containing (1,3,4-thiadiazol-2-yl)piperazine moieties as new type of antiHelicobacter pylori heterocycles. J. Serb. Chem. Soc. 2011, 76 (No. 2,) 201–210.
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74) Mohammad Hassan Moshafi, Maedeh Sorkhi, Saeed Emami, Maryam Nakhjiri, Azadeh
Yahya-Meymandi, Amir Soheil Negahbani, Farideh Siavoshi, Maryam Omrani, Eskandar
Alipour, Mohsen Vosooghi, Abbas Shafiee and Alireza Foroumadi, 5-Nitroimidazole-based
1,3,4-Thiadizoles: Heterocyclic Analogs of Metronidazole as Anti- Helicobacter pylori
Agents. Arch. Pharm. Chem. Life Sci. 2011, 344 (No. 3, March) 178–183.
75) Hassan Aryapour, Gholam Hossein Riazi, Alireza Foroumadi, Shahin Ahmadian, Abbas
Shafiee, Oveis Karima, Majid Mahdavi, Saeed Emami, Maedeh Sorkhi and Sirus Khodadady,
Biological evaluation of synthetic analogues of curcumin: chloro-substituted-2'hydroxychalcones as potential inhibitors of tubulin polimerization and cell proliferation. Med.
Chem. Res., 2011, 20, (No. 4, May) 503–510.
76) Azar Tahghighi, Farzane Rezazade Marznaki, Farzad Kobarfard, Siavoush Dastmalchi, Javid
Shahbazi Mojarrad, Sepideh Razmi, Sussan K. Ardestani, Saeed Emami, Abbas Shafiee,
Alireza Foroumadi, Synthesis and antileishmanial activity of novel 5-(5-nitrofuran-2-y1)1,3,4- thiadiazoles with piperazinyl-linked benzamidine substituents, Eur. J. Med. Chem.
2011, 46 (No. 6, June), 2602–2608.
77) Mehdi Khoobi, Saeed Emami, Gholamreza Dehghan, Alireza Foroumadi, Ali Ramazani,
Abbas Shafiee, Synthesis and free radical scavenging activity of coumarin derivatives
containing a 2-methylbenzothiazoline motif. Arch. Pharm. Chem. Life Sci. 2011, 344 (No. 9,
September) 588–594.
78) Mehdi khoobi, Alireza Foroumadi, Saeed Emami, Maliheh Safavi, Gholamreza Dehghan,
Babak H. Alizadeh, Ali Ramazani, Sussan K. Ardestani, Abbas Shafiee, Coumarin-based
bioactive compounds: facile synthesis and biological evaluation of coumarin-fused 1,4thiazepines. Chem. Biol. Drug Des. 2011, 78 (No. 4, October): 580–586.
79) Nematollah Ahangar, Adile Ayati, Eskandar Alipour, Arsalan Pashapour, Alireza Foroumadi,
Saeed Emami*, 1-[(2-Arylthiazol-4-yl)methyl]azoles as a new class of anticonvulsants:
Design, synthesis, in vivo screening and in silico drug-like properties. Chem. Biol. Drug Des.
2011, 78 (No. 5, Novamber) 844–852.
80) Saeed Emami *, Motahare Kazemi-Najafabadi, Soughra Pashangzadeh, Alireza Foroumadi,
Mohammad Ali Faramarzi, Nasrin Samadi, Mehraban Falahati, Roohollah Fateh and Mahtab
Ashrafi-Khozani, Synthesis and antifungal activity of 1-[(2-benzyloxy)phenyl]-2-(azol-1yl)ethanone derivatives: Exploring the scaffold flexibility. Chem. Biol. Drug Des. 2011, 78
(No. 6, December) 979–987.
81) Azar Tahghighi, Sepide Razmi, Mohammad Mahdavi, Parham Foroumadi, Sussan K.
Ardestani, Saeed Emami, Farzad kobarfard, Siavosh Dastmalchi, Abbas Shafiee, Alireza
Foroumadi. Synthesis and antileishmanial activity of 5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2amines containing N-[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl] moieties. Eur. J. Med. Chem.
2012, 50 (April) 124–128.
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82) Maryam Nakhjiri, Maliheh Safavi, Eskandar Alipour, Saeed Emami, Amir Farzin Atash,
Mona Jafari-Zavareh, Sussan K. Ardestani, Mehdi Khoshneviszadeh, Alireza Foroumadi,
Abbas Shafiee, Asymmetrical 2,6-bis(benzylidene)cyclohexanones: Synthesis, cytotoxic
activity and QSAR study. Eur. J. Med. Chem. 2012, 50 (April) 113–123.
83) Mehdi Khoobi, Ali Ramazani, Alireza Foroumadi, Saeed Emami, Farnaz Jafarpour, Amir
Mahyari, Katarzyna Ślepokura, Tadeusz Lis, and Abbas Shafiee, Highly cis-diastereoselective
synthesis of coumarin-based 2,3-disubstituted dihydrobenzothiazines by organocatalysis.
Helvetica Chimica Acta, 2012, 95 (April) 660–671.
84) Saeed Emami *, Seyed Jalal Hosseinimehr, Kami Shahrbandi, Ahmad Ali Enayati, Zahra
Esmaeeli, Synthesis and evaluation of 2(3H)-thiazole thiones as tyrosinase inhibitors. Arch.
Pharm. 2012, 345 (No. 8, August) 629–637.
85) Mahsa Ansari, Saeed Emami *, Mohammad A. Khalilzadeh, Malek Taher Maghsoodlou,
Alireza Foroumadi, Mohammad Ali Faramarzi, Nasrin Samadi, Sussan Kabudanian Ardestani,
Replacement of the methylene of dihydrochalcones with oxygen: Synthesis and biological
evaluation of 2-phenoxyacetophenones, Chem. Biol. Drug Des. 2012, 80 (issue 4, October)
591–597.
86) Negar Mohammadhosseini, Zahra Alipanahi, Eskandar Alipour, Saeed Emami, Mohammad
Faramarzi, Nasrin Samadi, Nika Khoshnevis, Abbass Shafiee, Alireza Foroumadi. Synthesis
and antibacterial activity of novel levofloxacin derivatives containing a substituted
thienylethyl moiety. DARU J. Pharm. Sci. 2012, 20 (August) 16.
87) Adile Ayati, Mehraban Falahati, Hamid Irannejad, Saeed Emami*, Synthesis, in vitro
antifungal evaluation and in silico study of 3-azolyl-4-chromanone phenylhydrazones, DARU
J. Pharm. Sci., 2012, 20 (October) 46.
88) Hassan Aryapour, Gholam Hossein Riazi, Shahin Ahmadian, Alireza Foroumadi, Majid
Mahdavi, Saeed Emami, Induction of apoptosis through tubulin inhibition in human cancer
cells by new chromene-based chalcones. Pharmaceutical Biology, 2012, 50 (No. 12,
December) 1551–1560.
89) Loghman Firoozpour, Najmeh Edraki, Maryam Nakhjiri, Saeed Emami, Maliheh Safavi,
Sussan Kabudanian Ardestani, Mehdi Khoshneviszadeh, Abbas Shafiee, Alireza Foroumadi,
Cytotoxic activity evaluation and QSAR study of chromene-based chalcones. Arch. Pharm.
Res. 2012, 35 (No. 12, December) 2117–2125.
90) Maliheh Safavi, Nasim Esmati, Sussan Kabudanian Ardestani, Saeed Emami, Soheila Ajdari,
Jamshid Davoodi, Abbas Shafiee, Alireza Foroumadi, Halogenated flavanones as potential
apoptosis-inducing agents: synthesis and biological activity evaluation. Eur. J. Med. Chem.
2012, 58 (December) 573–580.
91) Mohammad Azizmohammadi, Mehdi Khoobi, Ali Ramazani, Saeed Emami, Abdolhossein
Zarrin, Omidreza Firuzi, Ramin Miri, Abbas Shafiee, 2H-Chromene derivatives bearing
10
thiazolidine-2,4-dione, rhodanine or hydantoin moieties as potential anticancer agents. Eur. J.
Med. Chem., 2013, 59 (January) 15–22.
92) Adile Ayati, Saeed Emami*, Straightforward synthesis of thiazoline-incorporated
chalconoids from phenacyl halides. Mol. Divers., 2013, 17 (No. 1, February) 41–47.
93) Nouraddin Hosseinzadeh, Mohammad Hasani, Alireza Foroumadi, Hamid Nadri, Saeed
Emami, Nasrin Samadi, Mohammad Ali Faramarzi, Parastoo Saniee, Farideh Siavoshi, Neda
Abadian, Yasaman Mahmoudjanlou, Amirhossein Sakhteman, Alireza Moradi, Abbas Shafiee,
5-Nitro-heteroarylidene analogs of 2-thiazolylimino-4-thiazolidinones as a novel series of
antibacterial agents, Med. Chem. Res., 2013, 22 (No. 5, May), 2293–2302.
94) Seyyede Faeze Razavi, Mehdi Khoobi, Hamid Nadri, Amirhossein Sakhteman, Alireza
Moradi, Saeed Emami, Alireza Foroumadi, Abbas Shafiee, Synthesis and evaluation of 4substituted coumarins as novel acetylcholinesterase inhibitors. Eur. J. Med. Chem., 2013, 64
(June) 252–259.
95) Saeed Emami, Shahaboddin Shojapour, Mohammad Ali Faramarzi, Nasrin Samadi, Hamid
Irannejad, Synthesis, in vitro antifungal activity and in silico study of 3-(1,2,4-triazol-1yl)flavanones. Eur. J. Med. Chem., 2013, 66 (August) 480–488.
96) Azar Tahghighi, Saeed Emami, Sepide Razmi, Farzane Rezazade Marznaki, Sussan K.
Ardestani, Siavoush Dastmalchi, Farzad Kobarfard, Abbas Shafiee, Alireza Foroumadi, New
5-(nitroheteroaryl)-1,3,4-thiadiazols containing acyclic amines at C-2: synthesis and SAR
study for their antileishmanial activity, J. Enz. Inhib. Med. Chem., 2013, 28 (No. 4, Auggust):
843–852.
97) Saeedeh Noushini, Eskandar Alipour, Saeed Emami, Maliheh Safavi, Sussan Kabudanian
Ardestani, Ahmad Reza Gohari, Abbas Shafiee, Alireza Foroumadi, Synthesis and cytotoxic
properties of novel (E)-3-benzylidene-7-methoxychroman-4-one derivatives. DARU J. Pharm.
Sci. 2013 (April), 21: 31.
98) Fatemeh Molaverdi, Mehdi Khoobi, Saeed Emami, Masoumeh Alipour, Omidreza Firuzi,
Alireza Foroumadi, Gholamreza Dehghan, Ramin Miri, Fatemeh Shaki, Farnaz Jafarpour,
Abbas Shafiee, Polyoxygenated cinnamoylcoumarins as conformationally constrained analogs
of cytotoxic diarylpentanoids: synthesis and biological activity. Eur. J. Med. Chem. 2013, 68
(October) 103–110.
99) Saeed Emami, Ebrahim Ghafouri, Mohammad Ali Faramarzi, Nasrin Samadi, Hamid
Irannejad, Alireza Foroumadi, Mannich bases of 7-piperazinylquinolones and kojic acid
derivatives: synthesis, in vitro antibacterial activity and in silico study. Eur. J. Med. Chem.
2013, 68 (October) 185–191.
100)
Mehdi Khoobi, Masoumeh Alipour, Amirhossein Sakhteman, Hamid Nadri, Alireza
Moradi, Mehdi Ghandi, Saeed Emami, Alireza Foroumadi , Abbas Shafiee, Design,
synthesis, biological evaluation and docking study of 5-oxo-4,5-dihydropyrano[3,2-
11
c]chromene derivatives as acetylcholinesterase inhibitors and butyrylcholinesterase inhibitors.
Eur. J. Med. Chem. 2013, 68 (October) 260–269.
101)
Saeed Emami, Nima Shahrokhirad, Alireza Foroumadi, Mohammad Ali Faramarzi,
Nasrin Samadi, Narges Soltani-Ghofrani, 7-Piperazinylquinolones with methylene-bridged
nitrofuran scaffold as new antibacterial agents. Med. Chem .Res. 2013, 22 (No. 12, December)
5940–5947.
102)
Mandana Banimustafa, Asma Kheirollahi, Maliheh Safavi, Sussan Kabudanian
Ardestani, Hassan Aryapour , Alireza Foroumadi, Saeed Emami*, Synthesis and biological
evaluation of 3-(trimethoxyphenyl)-2(3H)-thiazole thiones as combretastatin analogs. Eur. J.
Med. Chem. 2013, 70 (December) 692–702.
103)
Ali Asadipour, Masoumeh Alipour, Mona Jafari, Mehdi Khoobi, Saeed Emami,
Hamid Nadri, Amirhossein Sakhteman, Alireza Moradi, Vahid Sheibani, Abbas Shafiee,
Alireza Foroumadi, Novel coumarin-3-carboxamides bearing N-benzylpiperidine moiety as
potent acetylcholinesterase inhibitors. Eur. J. Med. Chem. 2013, 70 (December) 623–630.
104)
Seyed Mostafa Ebrahimi, Mohammad Mahdavi, Saeed Emami, Mina Saeedi, Mehdi
Asadi, Loghman Firoozpour, Mehdi Khoobi, Kouros Divsalar, Abbas Shafiee,
AlirezaForoumadi, Green and catalyst-free one-pot synthesis of anthranilamide Schiff bases:
an approach toward sirtinol. Synthetic Communications, 2014, 44 (Issue 5), 665–673.
105)
Afsaneh Zonouzi, Roghieh Mirzazadeh, Maliheh Safavi, Sussan Kabudanian
Ardestani, Saeed Emami, Alireza Foroumadi, 2-Amino-4-(nitroalkyl)-4H-chromene-3carbonitriles as new cytotoxic agents, Iran. J. Pharm. Res., 2013, 12 (No. 4, Autumn), 679–
685.
106)
Bahram Letafat, Raheleh Shakeri, Saeed Emami, Saeedeh Noushini, Negar
Mohammadhosseini, Nayyereh Shirkavand, Sussan Kabudanian Ardestani, Maliheh Safavi,
Marjaneh Samadizadeh, Aida Letafat, Abbas Shafiee, Alireza Foroumadi, Synthesis and in
vitro Cytotoxic Activity of Novel Chalcone-like Agents. Iran. J. Basic Med. Sci. 2013, 16
(No. 11, November), 1155–1162.
107)
Masoumeh Alipour, Mehdi Khoobi, Saeed Emami, Saeed Fallah-benakohal, Seyedeh
Farnaz Ghasemi-Niri, Mohammad Abdollahi, Alireza Foroumadi, Abbas Shafiee,
Antinociceptive properties of new coumarin derivatives bearing substituted 3,4-dihydro-2Hbenzothiazines. DARU J. Pharm. Sci., 2014, 22 (No. 1, January), 9.
108)
Hamid Irannejad, Nima Naderi, Saeed Emami, Roja Qobadi Ghadikolaei, Alireza
Foroumadi, Tina Zafari, Ali Mazar-Atabaki, Sakineh Dadashpour, Microwave-assisted
synthesis and anticonvulsant activity of 5,6-bisaryl-1,2,4-triazine-3-thiol derivatives. Med.
Chem. Res. 2014, 23 (No. 5, May), 2503–2514.
109)
Mojtaba Babazadeh-Qazijahani, Hamid Badali, Hamid Irannejad, Mohammad Hosein
Afsarian, Saeed Emami,* Imidazolylchromanones containing non-benzylic oxime ethers:
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synthesis and molecular modeling study of new azole antifungals selective against
Cryptococcus gattii. Eur. Med. Chem. 2014, 76 (April) 264–273.
110)
Ali Ramazani, Mehdi Khoobi, Azar Torkaman, Fatemeh Zeinali Nasrabadi, Hamid
Forootanfar, Mojtaba Shakibaie, Mandana Jafari, Alieh Ameri, Saeed Emami, Mohammad
Ali Faramarzi, Alireza Foroumadi, Abbas Shafiee, One-pot, four-component synthesis of
novel cytotoxic agents 1-(5-aryl-1,3,4-oxadiazol-2-yl)-1-(1H-pyrrol-2-yl)methanamines, Eur.
J. Med. Chem., 2014, 78 (May), 151–156.
111)
Saeed Emami*, Touba Banipoulad, Hamid Irannejad, Alireza Foroumadi, Mehraban
Falahati, Mahtab Ashrafi-Khozani, Somaye Sharifynia, Imidazolylchromanones containing
alkyl side chain as potential lanosterol 14α-demethylase inhibitors: synthesis, antifungal
activity and docking study. J. Enz. Inhib. Med. Chem., 2014, 29 (No. 2, April) 263–271.
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