Dr Alastair McBeath
Dr. Alastair J. A. McBeath
Publication List (last updated October 2015)
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Fourrier M., Lester K., Markussen, T., Falk, K., Secombes C.J., McBeath, A., and Collet B. (accepted). Dual
mutation events in the haemagglutinin-esterase and F protein from an Infectious salmon anaemia virus HPR0
genotype promote viral fusion and activation by an ubiquitous host protease. PLOS One
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*Aamelfot, M., *McBeath, A., Christiansen, D., Matejusova, I. and Falk, K. (2015). Infectious salmon anaemia virus
(ISAV) mucosal infection in Atlantic salmon. Veterinary Research 46:120.
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Aamelfot, M., Dale, O. B., McBeath, A., Falk, K. (2015). Host tropism of infectious salmon anaemia virus (ISAV) in
marine and freshwater fish species. Journal of Fish Diseases. 38(8):687-94.
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*McBeath, A.,*Aamelfot, M., Christiansen, D., Matejusova, I., Markussen, T., Dale, O. B., Weli, S. and Falk, K. (2015).
Immersion challenge with low and highly virulent infectious salmon anaemia virus reveals different pathogenesis in
Atlantic salmon. Journal of Fish Diseases 38(1):3-15.
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McBeath, A., Ho, Y.M., Aamelfot, M., Hall, M., Christiansen, D., Markussen, T., Falk, K. and Matejusova, I. (2014).
Low virulent infectious salmon anaemia virus (ISAV) replicates and initiates the immune response earlier than a
highly virulent virus in Atlantic salmon gills. Veterinary Research 45:83
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McBeath, A. 2014. Studying ISA, the International Way. Fish Farmer Magazine: 37(5 - September/October): 40
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Fourrier M., Lester K., Thoen E., Mikalsen A., Evensen Ø., Falk K., Collet B. and McBeath, A., (2014). Deletions in
the Highly Polymorphic Region (HPR) of Infectious Salmon Anaemia Virus HPR0 haemagglutinin-esterase enhance
viral fusion and influence the interaction with the fusion protein. Journal of General Virology, 95(5): 1015-1024.
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Pert, C.C., Fryer, R.J., Cook, P., Kilburn, R., McBeath, S., McBeath, A., Matejusova, I., Urquhart, K., Weir, S.J.,
McCarthy, U., Collins, C., Amundrud, T. & Bricknell, I.R. (2014). Using sentinel cages to estimate infestation
pressure on salmonids from sea lice in Loch Shieldaig, Scotland. Aquaculture Environment Interactions, 5: 49-59.
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Hall, M., R.J Smith, E.S Munro, I Matejusova, C.E.T Allan, A.G Murray, S.J Duguid, N.K.G. Salama, A McBeath,
I.S. Wallace, N. Bain, M. Marcos-Lopez, and R.S Raynard. (2013). Epidemiology and Control of an Outbreak of
Viral Haemorrhagic Septicaemia in Wrasse Around Shetland Commencing 2012. Scottish Marine and Freshwater
Science 4 (3):49.
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McBeath, A., Bain, N., Fourrier, M., Collet, B. and Snow, M. (2013). A strand specific real-time RT-PCR method for
the targeted detection of the three species (vRNA, cRNA and mRNA) of Infectious Salmon Anaemia Virus (ISAV)
replicative RNA. Journal of Virological Methods, Jan;187(1):65-71.
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*McBeath, A., *Fourrier ,M., Munro, E., Falk, K. and Snow, M. (2011). Presence of a full length highly polymorphic
region (HPR) in the ISAV haemagglutinin-esterase does not affect the primary functions of receptor binding and
esterase activity. Archives of Virology, 156(12): 2285-2289.
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Penston, M.J., McBeath, A.J.A. and Millar, C.P. (2011). Densities of planktonic Lepeophtheirus salmonis before
and after an Atlantic salmon farm relocation. Aquaculture Environment Interactions. 1: 225-232.
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Campbell, S., McBeath, A., Secombes, C., Snow, M. and Collet, B. (2011). Interferon response following infection
with genetically similar isolates of viral haemorrhagic septicaemia virus (VHSV) exhibiting contrasting virulence in
rainbow trout. Fish and Shellfish Immunology, 30 (1): 287-294.
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McBeath, A., Bain, N. and Snow, M. (2009). Surveillance for infectious salmon anaemia virus HPR0 in marine
Atlantic salmon farms across Scotland. Diseases of Aquatic Organisms 87:3 161-169.
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Pan, M., McBeath, A., Hay, S., Pierce, G. J., & Cunningham, C. O. (2008). Real-time PCR assay for detection and
relative quantification of Liocarcinus depurator larvae from plankton samples. Marine Biology 153 (5): 859-870.
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Matejusová, I., McKay, P., McBeath, A.J.A., Collet, B. & Snow, M. (2008). Development of a sensitive and
controlled real-time RT-PCR assay to screen for the presence of viral haemorrhagic septicaemia virus (VHSV) in
the marine salmonid aquaculture industry in Scotland. Diseases of Aquatic Organisms 80: 137-144.
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Dr Alastair McBeath
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Collet, B., Bain, N., Prevost, S., Besinque, G., McBeath, A & Snow, M (2008). Isolation of an Atlantic salmon
(Salmo salar) Signal transducer and activator of transcription STAT-1 gene: kinetics of expression upon ISAV or
IPNV infection. Fish & ShelIfish Immunology 25: 861-867.
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Lockhart, K., McBeath, A.J.A., Collet, B., Snow, M. and Ellis, A.E. (2007). Expression of Mx mRNA following
infection with IPNV is greater in IPN-susceptible Atlantic salmon post-smolts than in IPN-resistant Atlantic salmon
parr. Fish & Shellfish Immunology 22:151-156.
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McBeath A.J.A., Snow M., Secombes C.J., Ellis A.E. and Collet B. (2007). Expression kinetics of interferon and
interferon-induced genes in Atlantic salmon (Salmo salar) following infection with infectious pancreatic necrosis
virus and infectious salmon anaemia virus. Fish and Shellfish Immunology 22, 230-241.
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McBeath, A.J.A., Penston, M.J., Snow, M., Cook, P.F., Bricknell I.R. and Cunningham, C.O. (2006). Development
and application of real-time PCR for specific detection of Lepeophtheirus salmonis and Caligus elongatus larvae in
Scottish plankton samples, Diseases of Aquatic Organisms 73:141-150.
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Snow, M., McKay, P., McBeath, A.J., Black, J., Doig, F., Kerr, R., Cunningham, C.O., Nylund, A. and Devold, M.
(2006) Development, application and validation of a Taqman real-time RT-PCR assay for the detection of infectious
salmon anaemia virus (ISAV) in Atlantic salmon (Salmo salar). Dev Biol (Basel) 126, 133-45; discussion 325-6
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McBeath, A. J. A., Collet, B., Paley, R., Duraffour, S., Aspehaug, V., Biering, E., Secombes, C. J. and Snow, M.
(2006) Identification of an interferon antagonist protein encoded by segment 7 of Infectious Salmon Anaemia Virus.
Virus Research 115, 176-184.
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Matejusová, I., Gelnar, M., McBeath, A. J. A., Collins, C. M. & Cunningham, C. O. (2001). Molecular markers for
gyrodactylids (Gyrodactylidae: Monogenea) from five fish families (Teleostei). International Journal for Parasitology
31(7), 738-745.
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McBeath, A. J. A., Burr, K. L-A. & Cunningham, C. O. (2000). Development and use of a DNA probe for
confirmation of cDNA from Infectious Salmon Anaemia virus (ISAV) in PCR products. Bull. Eur. Assoc. Fish Pathol.,
20(3) pp130 – 134.
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