Investigation of acute diarrhoea in care homes/ elderly patients For general advice on assessment of acute diarrhoea see clinical knowledge summary: http://www.cks.nhs.uk/diarrhoea_adults_assessment#-471656 Assess severity – ensure patient does not need hospital admission Exclude other causes e.g. overflow, known sources of enteric infection, laxatives, high energy feeds, known inflammatory bowel disease. Suspect HCAI (C diff) if patient was inpatient at hospital or prescribed antibiotics in preceding 8 weeks and falls into an at risk group eg elderly, frail, prev C diff infection (toxin positive or negative), taking high dose PPI, clinical contact of C diff (although person to person transmission is unusual) . There are no clinical features to make a C diff infection more likely. Send stool spec for C diff testing if suspected. DO NOT TEST FOR C DIFF WITHIN 3 MONTHS OF A POSITIVE RESULT. The result will be positive anyway so treat if symptomatic according to the advice of a consultant microbiologist. Care homes should not be sending in specimens without having liaised with the responsible primary care clinician. Advice on the management of C diff will always accompany the positive result. If in doubt ask the microbiologist. Isolate suspected cases while awaiting a result. Doldon July 2012