Alper-JCCC Molecular Epidemiology Symposium: Advances of Gene-Environmental Interaction and Lung and Other Smoking-related Cancers 8:00 AM – 6:00 PM, April 14, 2007 Gonda Building, First Floor Conference Room The symposium is sponsored by the Ann Fitzpatrick Alper Program in Environmental Genomics and the UCLA Jonsson Comprehensive Cancer Center (JCCC), the symposium is also co-sponsored by the UCLA Center for Occupational and Environmental Health (COEH), UCLA Lung SPORE, and the UCLA Molecular Epidemiology Training and Research Program. 7:00-7:50 Breakfast 7:50-8:20 Introduction: Dr. Roshan Bastani, Dr. Zuo-Feng Zhang, Dr. Jeanette Papp and Dr. Stephen Dubinett Session One: Keynote Lectures 8:20-9:20 Advances of Genetic Susceptibility of Lung and Head and Neck Cancer Dr. Paolo Boffetta Coordinator, Genetics and Epidemiology Cluster International Agency for Research on Cancer 150 cours Albert Thomas 69008 Lyon France Tel +33-472738554 Fax +33-472738320 "Dr. Paolo Boffetta" <boffetta@iarc.fr> 9:20-10:20 NAT2, GSTM1, occupational and tobacco exposures, and bladder cancer: historical perspective and lessons learned about studying gene-environment interactions Nathaniel Rothman, M.D., M.P.H., M.H.S. Senior Investigator Division of Cancer Epidemiology and Genetics National Cancer Institute Executive Plaza South, Room 8116 6120 Executive Boulevard MSC 7242 Bethesda, Maryland 20892-7335 1 Phone: 301-496-9093 Fax: 301-402-1819 E-mail: rothmann@mail.nih.gov 10:20-10:30 Tea Break Session 2: Gene-Environmental Interaction on Risk, Progression and Chemoprevention of Lung and Smoking-related Cancers 10:30-11:10 Tobacco Carcinogenesis: a Pathway-based Approach Xifeng Wu, MD, PhD Professor of Epidemiology Department of Epidemiology - Box 1340 The University of Texas M. D. Anderson Cancer Center 1155 Pressler Blvd Houston, TX 77030 CPB 4.3209 Telephone: (713) 745-2485 Fax: (713) 792-4657 E-mail: xwu@mdanderson.org 11:10-11:50 Molecular Therapeutics and Chemoprevention of Lung Cancer Ruiwen Zhang, MD, PhD, DABT Professor, Clinical Pharmacology, Pharmacology and Toxicology Director, Cancer Pharmacology Laboratory University of Alabama at Birmingham VH 113, Box 600 1670 University Blvd. Birmingham, AL 35294-0019 (205) 934-8558 (Phone) (205) 975-9330 (FAX) Ruiwen.Zhang@ccc.uab.edu 11:50-12:30 Whole genome association study of lung cancer Jianfeng Xu, M.D. Dr.PH. Professor of Public Health and Cancer Biology Director, Program for Genetic and Molecular Epidemiology of Cancer 2 Associate Director, Center for Human Genomics Wake Forest University School of Medicine Medical Center Blvd Winston-Salem, NC 27157 Tel: (336) 713-7500 Fax: (336) 713-7566 Email: jxu@wfubmc.edu 12:30-1:30 Lunch 1:30-2:10 Gene-Environment Interaction on Lung Cancer Progression and Survival Ping Yang, MD, PhD Professor Mayo Clinic College of Medicine Email: Yang.Ping@mayo.edu http://mayoresearch.mayo.edu/mayo/research/staff/yang_p.cfm 2:10-2:50 Inflammation and Lung Cancer Risk Qiuyin Cai, MD, PhD Assistant Professor Vanderbilt Epidemiology Center Institute of Medicine and Public Health Vanderbilt University Medical Center PRB 636, 2220 Pierce Avenue Nashville, TN 37232-6838 Phone : 615-936-1351 Fax : 615-936-1790 Email : qiuyin.cai@vanderbilt.edu 2:50-3:30 Molecular Epidemiology Study of Indoor Air Pollution and Lung Cancer. Qing Lan, M.D., M.P.H., Ph.D. Investigator Occupational & Environmental Epidemiology Branch Division of Cancer Epidemiology & Genetics National Cancer Institute 6120 Executive Blvd. EPS Room 8109 Bethesda, Maryland 20892-7238 Telephone: (301) 435-4706 3 Fax (301) 402-1819 E-mail: qingl@mail.nih.gov 3:30-3:40 Tea Break 3:40-4:00 UCLA Lung Cancer Chemoprevention Trial, An Update Jenny Mao, MD Associate Professor UCLA School of Medicine Med-Pul & Critical Care Box 951690, 37-131 CHS Los Angeles, CA 90095-1690 Phone : 310-825-3100 Fax : 310-206-8622 Email : jmao@mednet.ucla.edu 4:00-4:20 Molecular Epidemiology of Lung Cancer in Chinese Population Hongbing Shen, MD, PhD Professor of Epidemiology Dean, School of Public Health Nanjing Medical University Nanjing 210029, Jiangsu People¡¯s Republic of China Tel:(86)25-8686-2756 Fax:(86)25-8652-7613 Email:hbshen@njmu.edu.cn 4:20-4:40 XRCC1/LIG1 polymorphisms, Indoor Air pollution & risk of lung cancer in Taiyuan, China Lina Mu, MD, PhD Associate Professor Department of Epidemiology Fudan University School of Public Health Shanghai 200032 People’s Republic of China Email: ln_mu2000@yahoo.com 4 Li Liu, MD Director, Chronic Disease Prevention and Control Taiyuan Center for Chronic Disease Prevention and Control Taiyuan CDC, China Tel: 0351-7227554 4:40-5:00 Passive Smoking and Head and Neck Cancer among Non-Smokers Amy Lee, PhD Gene Environment Epidemiology Group International Agency for Research on Cancer 150 Cours Albert-Thomas 69008 Lyon France email: <amyleeucla@gmail.com> 5:00-5:20 NAD(P)H:quinone oxidoreductase 1 (NQO1) Pro187Ser polymorphism and the risk of lung cancer Chun (Rebecca) Chao, PhD Department of Research and Evaluation Kaiser Permanente Southern California 100 S. Los Robles, Suite 201 Pasadena, CA 91101 Tel: 626-564-3797 Fax: 626-564-3409 Email: chun.r.chao@kp.org 5:20-5:40 Lung Cancer Susceptibility (LCS) Study Survival Outcomes: An Update Rebecca Suk Heist, MD MPH Instructor in Medicine, Harvard Medical School Massachusetts General Hospital Cancer Center Yawkey 7B 55 Fruit Street Boston MA 02114 phone: 617 724 4000 fax: 617 726 0453 RHEIST@PARTNERS.ORG 5 6