South West Region
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Sepsis Research, initiated between 1 January 2001 and 31 December 2002 Click on the hyperlinks below to be taken to that region. To search for individual keywords in this document, go to the ‘Edit’ menu and click ‘Find’ (or hold down ‘Control’ and ‘F’ simultaneously). Eastern London Northern & Yorkshire North-West Scotland South-East Trent West Midlands Wales South-West Eastern Region TITLE: CORTICUS - Corticosteroid therapy in septic shock CONTACT: Dr M Garfield UNIT: Ipswich Hospital NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0254112093 TITLE: International Neonatal Immunotherapy Study CONTACT: Doctor Paramasivam Sivakuma UNIT: Luton and Dunstable NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0594125137 TITLE: PROGRAMS: a prophylactic gramulocyte macrophage colony stimulating factor to reduce sepsis in pre-term neonates CONTACT: Dr J Gould UNIT: Ipswich Hospital NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0254098169 TITLE: Prophylactic Granulocyte-Macrophage Colony Stimulating Factor (GMCSF) to reduce sepsis in preterm neonates - PROGRAMS. ISRCTN 42553489 CONTACT: Dr J D Eason UNIT: East Norfolk and Waveney Research Consortium Norfolk and Norwich University Hospital/Norwich PCT http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0547099395 (back to top of document) London Region TITLE: A Multicentre randomised controlled trial of prophylactic granulocyte macrophage colon stimulating factor (GM-CSF) to reduce sepsis in preterm neonates - observational study of infants/parents CONTACT: Mrs Liz Schroeder UNIT: Hammersmith Hospital NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0016121142 TITLE: An open label safety study for recombinant human activated protein C in severe sepsis. A Phase 3b clinical trial. CONTACT: Dr Simon Nadel UNIT: St Marys NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0241098109 TITLE: An open label safety study for recombinant human activated protein C in severe sepsis. A phase 3b clinical trial. [MT/AB/MREC/00/7/64] CONTACT: Dr Neil Soni UNIT: Chelsea and Westminster Healthcare NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0060099603 TITLE: An open label study of recombinant Human Activated Protein C in severe sepsis. A phase 3b clinical trial (protocol F1K-MC-EVBF) CONTACT: Dr MJ Peters UNIT: Great Ormond Street Hospital for Children NHS Trust / Institute of Child Health. http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0012095825 TITLE: An open-label study of Recombinant Human Activated Protein C in Severe Spsis a phase 3b clinical trial CONTACT: Professor E David Bennett UNIT: St Georges Healthcare NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0236098081 TITLE: Bacteraemia following conservative dentogingival manipulation procedures in children CONTACT: Mrs H Hawazen UNIT: UCL Hospitals NHS Foundation Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0263092955 TITLE: Functional ability following amputation after meningococcal sepsis. CONTACT: Dr Tom Allport UNIT: St Marys NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0241083508 TITLE: Glutathione synthesis in critically ill septic infants and children CONTACT: Mr M Chowdhury UNIT: Great Ormond Street Hospital for Children NHS Trust / Institute of Child Health. http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0012108124 TITLE: INIS CONTACT: Dr Khalid N Haque UNIT: Epsom and St Helier University Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0112083926 TITLE: INIS CONTACT: Dr Nic Wilson UNIT: Whipps Cross University Hospital NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0080092707 TITLE: Investigation of the efficacy and safety of Drotrecogin Alfa (activated) in Pediatric Severe Sepsis CONTACT: Dr MJ Peters UNIT: Great Ormond Street Hospital for Children NHS Trust / Institute of Child Health. http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0012128265 TITLE: PROGRAMS CONTACT: Dr Elia Maalouf UNIT: Homerton University Hospital NHS Foundation Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0024096193 TITLE: PROGRAMS follow up CONTACT: Dr Charlotte Daman UNIT: University Hospital Lewisham NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0124139293 TITLE: Promoting glutathione synthesis in critically-ill septic infants and children CONTACT: Professor Agostino Pierro UNIT: The BUPA Foundation http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0053115498 TITLE: Prophylactic granulocyte_Macrophage colony stimulating factor (GM_CSF) to reduce Sepsis in preterm neonates (PROGRAMS). CONTACT: Dr Neena Modi UNIT: Newham University Hospital NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0147102136 TITLE: Prophylactic granulocyte-macropharge colony stimulating factor (GMCSF) to reduce sepsis in pre-term neonates. CONTACT: Dr Enitan M Ogundipe UNIT: Chelsea and Westminster Healthcare NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0060102264 TITLE: Randomised controlled trial of early plasmafiltration in severe sepsis CONTACT: Dr MJ Peters UNIT: Great Ormond Street Hospital for Children NHS Trust / Institute of Child Health. http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0012108080 TITLE: Role of toll receptors in the cardiovascular changes associated with gramnegative septic shock CONTACT: Professor Jane A Mitchell UNIT: Royal Brompton and Harefield NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0201097634 TITLE: Significance of serum bactericidal activity (SBA) test in ICU patients treated empirically for sepsis CONTACT: Dr Panagiotis Kaltsas UNIT: Hammersmith Hospital NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0016111479 TITLE: The use of C-reactive Protein (CRP) in the diagnosis of bacterial sepsis with febrile neutropenia in children CONTACT: Dr Ali Bokhari UNIT: Queen Marys Sidcup NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0533110573 TITLE: Thioredoxin and endothelial activation in sepsis CONTACT: Professor TW Evans UNIT: Royal Brompton and Harefield NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0201103802 (back to top of document) Northern and Yorkshire Region TITLE: An open label safety study for recombinant human activated protein C in severe sepsis - A phase IIIb clinical trial CONTACT: Dr John Esmond UNIT: Calderdale and Huddersfield NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0083099517 TITLE: Conformational changes in the structure of albumin and its degradation into fragments in meningococcal sepsis CONTACT: Dr Paula McQueen UNIT: NHS Executive Northern and Yorkshire http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0461108795 TITLE: Effect of a combined urokinase and flucloxacillin line lock in treatment of acute haemodialysis catheter related sepsis. CONTACT: Dr P Laboi UNIT: Leeds Teaching Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0436121432 TITLE: INIS (International Neonatal Immunotherapy Study) CONTACT: Dr Eilean Crosbie UNIT: Calderdale and Huddersfield NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0083114186 TITLE: International Neonatal Immunotherapy Study (INIS) CONTACT: Dr Anil Gupta UNIT: North Tees and Hartlepool NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0159093857 TITLE: International Neonatal Immunotherapy Study (INIS). CONTACT: Dr Peter Brocklehurst UNIT: Bradford Teaching Hospitals NHS Foundation Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0050111061 TITLE: Mitochondrial DNA sequence variation and outcomes from human sepsis CONTACT: Dr S V Baudouin UNIT: Newcastle upon Tyne Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0503117359 TITLE: The influence of venous impulse foot pumps on Pin tract infections CONTACT: Mr B Venkateswaran UNIT: Bradford Teaching Hospitals NHS Foundation Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0050111063 (back to top of document) North-West TITLE: A prospective study for estimation of cardiac responsiveness to fluid administration using stroke volume variation in mechanically ventilated patients with severe sepsis CONTACT: Dr Gernot Marx UNIT: Royal Liverpool and Broadgreen University Hospitals Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0207097767 TITLE: A prospective study of the use of mupirocin to prevent pin-site infections CONTACT: Mr RA Wilkes UNIT: Salford Royal Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0217083985 TITLE: Bioelectral impedance spectroscopy in monitoring capillary leak syndrome in Meningcoccal sepsis CONTACT: Dr David Stewart UNIT: Central Manchester and Manchester Childrens University Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0129097157 TITLE: Evaluation of sensitivity of non-invasive determinants for capillary leakage syndrome in septic patients CONTACT: Dr Gernot Marx UNIT: Royal Liverpool and Broadgreen University Hospitals Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0207104817 TITLE: INIS - International Neonatal Immunotherapy Study CONTACT: Dr Lydia S Bowden UNIT: South Manchester University Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0226134841 TITLE: International Neonatal Immunotherapy Study CONTACT: Dr Meera Lama UNIT: East Lancashire Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0300113921 TITLE: International Neonatal Immunotherapy Study (INIS) CONTACT: Dr M Yadav UNIT: Bolton Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0010106303 TITLE: Investigation of the efficacy and safety of Drotrecogin Alfa (Activated) in Paediatric severe sepsis CONTACT: Dr PB Baines UNIT: Royal Liverpool Childrens NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0206131759 TITLE: PROGRAMS - A multi-centre, randomised controlled trial of prophylactic granulocyte-macrophage colony-stimulating factor (GM-CSF) to reduce sepsis in preterm neonate CONTACT: Dr A J B Emmerson UNIT: Central Manchester and Manchester Childrens University Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0453102490 TITLE: PROGRAMS - A multi-centre, randomised controlled trial of prophylactic granulocyte-macrophage colony-stimulating factor (GM-CSF) to reduce sepsis in preterm neonates CONTACT: Dr Modi N UNIT: Liverpool Womens Hospital NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0128094716 TITLE: Selenium replacement and outcome in critically ill septic patients. CONTACT: Dr SM Mostafa UNIT: Royal Liverpool and Broadgreen University Hospitals Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0207104826 (back to top of document) Scotland TITLE: A study of early predictors of renal dysfunction in septic shock CONTACT: Dr B H Cuthbertson UNIT: NHS Grampian http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0411110680 TITLE: BSAC Bacteraemia Resistance Study. CONTACT: Dr G Phillips UNIT: Tayside Research Consortium http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0405091422 TITLE: Comparison of CT and FDG PET in the localisation of intra-abdominal septic foci in critically ill patients CONTACT: Dr Steve McCallum UNIT: NHS Grampian http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0411110708 TITLE: Corticosteroid therapy of septic shock (CORTICUS) CONTACT: Dr B H Cuthbertson UNIT: NHS Grampian http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0411110679 TITLE: INIS CONTACT: Dr William McGuire UNIT: Tayside Research Consortium http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0405103477 TITLE: INIS (international neonatal immunotherapy study) CONTACT: Dr S Ibhanesebhor UNIT: Lanarkshire Acute Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0399131652 TITLE: International Neonatal Immunotherapy Study CONTACT: Dr Ben J Stenson UNIT: The Lothian University Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0519099234 TITLE: International Neonatal Immunotherapy Study (INIS). CONTACT: Dr Brian Jones UNIT: North Glasgow University Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0394113726 TITLE: PROGRAMS CONTACT: Dr Peter W Fowlie UNIT: Tayside Research Consortium http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0405098702 TITLE: Prophylactic Granulocyte-Macrophage Colony Stimulating Factor to reduce sepsis in preterm neonates (PROGRAMS). CONTACT: Dr Andrew Powls UNIT: North Glasgow University Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0394105468 TITLE: The effects of systemic corticosteroids on the inflammatory response and oxidative stress in septic shock - sub study CONTACT: Dr B H Cuthbertson UNIT: NHS Grampian http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0411123388 TITLE: The role of polymorphisms on the TREM-1 receptor in sepsis and the effect on the inflammatory response CONTACT: Dr H F Galley UNIT: NHS Grampian http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0411130135 (back to top of document) South East TITLE: An Open-Label Study of Recombinant Human Activated Protein C in Severe Sepsis CONTACT: Dr Atul Kapila UNIT: Royal Berkshire and Battle Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0199097590 TITLE: INIS CONTACT: Dr Peter Brocklehurst UNIT: Surrey and Sussex Healthcare NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0109118492 TITLE: International Neonatal Immunotherapy Study - INIS CONTACT: Dr Tony Ducker UNIT: Medway NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0132108433 TITLE: International Neonatal Immunotherapy Study (INIS) CONTACT: Dr David Long UNIT: East Kent Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0514135940 TITLE: PROGRAMS - Prophylactic granulocyte macrophage colony stimulating factor (GMCSF) to reduce sepsis in pre-term neonates CONTACT: Dr Fiona Weir UNIT: Brighton and Sussex University Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0051113378 TITLE: PROpylactic GRAulocyte-Macrophage colony stimulating factor to reduce Sepsis in preterm infants - PROGRAMS CONTACT: Dr Bov Jani UNIT: Medway NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0132091312 TITLE: The Use of Teicoplanin in the Treatment of Septicaemia Caused by Coagulase Negative Staphylococci - UKCCSG Study CONTACT: Dr Anne Davidson UNIT: Brighton and Sussex University Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0051113380 (back to top of document) South West Region TITLE: International Neonatal Immunotherapy Study (INIS) CONTACT: Dr Anoo Jain UNIT: United Bristol Healthcare NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0264135970 TITLE: International Neonatal Immunotherapy Study (INIS) CONTACT: Professor A Whitelaw UNIT: North Bristol NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0234093841 TITLE: PROGRAMS Study CONTACT: Dr D J Evans UNIT: North Bristol NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0234104405 TITLE: PROGRAMS. Prophylactic granulocyte-macrophage colony stimulating factor to reduce sepsis in preterm neonates. CONTACT: Dr Cairns UNIT: United Bristol Healthcare NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0264146225 TITLE: Sepsis occurrence in the acutely ill patient (SOAP) CONTACT: Dr Chris Roberts UNIT: Gloucestershire R&D Consortium http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0106114448 (back to top of document) Trent Region TITLE: A comparison of cardiac output measurement in patients with sepsis using the TruCCOMS and PiCCO continuous cardiac output monitors versus thermodilution. CONTACT: Dr Aamer Ahmed UNIT: University Hospitals of Leicester NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0123094575 TITLE: A Multicentre Randomised Controlled Trial of Prophylactic GranulocyteMacrophage Colony Stimulating Factor (GM-CSF) to Reduce Sepsis in Preterm Neonates (PROGRAMS) CONTACT: Dr S P Wardle UNIT: Queens Medical Centre University Hospital NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0192104719 TITLE: Glutamine Supplementation of Parental Nutrition in Surgical Newborn Infants CONTACT: Mr S J Singh UNIT: Queens Medical Centre University Hospital NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0192119042 TITLE: International Neonatal Immunotherapy Study (INIS) CONTACT: Dr Loretta Davies-Reynolds UNIT: Barnsley District General Hospital NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0034136497 TITLE: International Neonatal Immunotherapy Study (INIS) CONTACT: Ms Carole Campbell UNIT: Nottingham City Hospital NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0170106727 TITLE: Investigation of the role of molecular techniques in the mangement of sepsis in total joint arthroplasty CONTACT: Dr P Norman UNIT: Northern General Hospital NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0164112567 TITLE: Open-label safety study for recombinant human activated protein C in severe sepsis. (Phase III b Clinical Trial). CONTACT: Dr David Edbrooke UNIT: Sheffield Teaching Hospitals NHS Foundation Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0059096440 (back to top of document) Wales TITLE: A Prospective, Open, Multicentre, Phase II Study of Antithrombin Concentrate in Meningococcal Septicaemia CONTACT: Dr G Findlay UNIT: South Bro Taf R&D Consortium http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0054100598 TITLE: An Open-Label study of Recombinant Human Activated Protein C in Severe Sepsis A Phase 3b Clinical Trail CONTACT: Dr BJM Ferguson UNIT: IMH Consortium http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0044095726 TITLE: CORTICUS - Corticosteroid Therapy of Septic Shock. CONTACT: Dr G Findlay UNIT: South Bro Taf R&D Consortium http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0054139586 TITLE: International Neonatal Immunotherapy Study (INIS) CONTACT: Dr Iyad Al-Muzaffar UNIT: Pontypridd and Rhondda NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0046111191 TITLE: Meningococcal Septicaemia CONTACT: Mrs T.E. Rogers UNIT: South Bro Taf R&D Consortium http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0054095784 TITLE: PROGRAMS (Prophylactic Granulocyte-Macrophage colony stimulating factor (GM-CSF) to reduce sepsis in preterm neonates). CONTACT: Dr. PH Cartlidge UNIT: South Bro Taf R&D Consortium http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0054114564 TITLE: PROGRAMS TRIAL CONTACT: Dr Jean Matthes UNIT: IMH Consortium http://www.nrr.nhs.uk/ViewDocument.asp?ID=M0044095727 (back to top of document) West Midlands Region TITLE: Double blind prospective randomised controlled trial of antibiotic prophylaxis for percutaneous endoscopic gastrostomy (PEG) CONTACT: Dr B J M Jones UNIT: The Dudley Group of Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0557099429 TITLE: INIS - International Neonatal Immunotherapy Study CONTACT: Dr B Kumararatine UNIT: The Royal Wolverhampton Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0214100164 TITLE: INIS International Neonatal Immunotherapy Study CONTACT: Dr Julie Nycyk UNIT: Sandwell and West Birmingham Hospitals NHS Trust http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0064104560 TITLE: INIS Study CONTACT: Dr S V Deshpande UNIT: Shrewsbury and Telford Research and Development Consortium http://www.nrr.nhs.uk/ViewDocument.asp?ID=N0375109708 (back to top of document)
