Curriculum vitae
Michael D. Mendenhall, Ph.D.
Department of Molecular & Cellular Biochemistry
275 BBSRB
University of Kentucky
741 South Limestone
Lexington, KY 40536
(859) 257-5379 (office), 257-5428 (laboratory)
email: mendenh@uky.edu
Personal
3525 Coltneck Lane
TELEPHONE: (859) 271-6878
CELL: (859) 421-3731
DATE OF BIRTH: 2 December 1956
HOME ADDRESS:
Education
GRADUATE:
1974-1978
1978-1985
POSTDOCTORAL:
1985-1986
UNDERGRADUATE:
1986-1988
A.B. Biochemistry, University of California, Berkeley
Ph.D., Molecular Biology, University of Wisconsin, Madison,
Advisor: Associate Professor Michael R. Culbertson
University of California, Santa Barbara, Advisor: Associate
Professor Steven I. Reed
Scripps Clinic & Research Institute, LaJolla, CA, Advisor:
Assistant Member Steven I. Reed
Employment
1977, 1978
1988-1994
1994-present
Technician for Professor Randy Schekman, University of California,
Berkeley
Assistant Professor of Biochemistry with a joint appointment at the L.P.
Markey Cancer Center, University of Kentucky, Lexington, KY
Associate Professor of Biochemistry with a joint appointment at the L.P.
Markey Cancer Center, University of Kentucky, Lexington, KY
Other Experience
1977-1978
Undergraduate research under supervision of Professor Randy
Schekman, University of California, Berkeley
Michael Mendenhall
2
Teaching
1988-1989
BCH618:
Seminar in biochemistry. Fall. 14 hours class time, 5-7 hours advising. Advisor
for Lori Dwyer.
BCH619:
Seminar in biochemistry. Spring. 13 hours class time, 5-7 hours advising.
Advisor for Reichang Yan and Bao-Li Yang.
Topics in Biochemistry (research proposal writing): Spring. Advisor for Bao-Li
Yang.
BCH780:
BCH640:
Research in biochemistry. Summer. Advisor for Bettye Ridley.
1989-1990
BCH618:
BCH640:
BCH615:
BCH619:
BCH780:
BCH640:
BCH640:
Seminar in biochemistry. Fall. 14 hours class time, 5-7 hours advising. Advisor
for Swati Joshi.
Research in biochemistry. Fall. Advisor for Bettye Ridley and Michael
Shoemaker.
Molecular biology and genetics. Spring. 13.5 hours of lecture/discussion (nine
1.5 hour sessions, 20-30 students).
Seminar in biochemistry. Spring. Course director. (13 hours class time; 5-7
hours advising). Advisor for Carrie Rinker-Schaeffer.
Topics in biochemistry (research proposal writing). Spring. Advisor for Debbie
Gunnersen.
Research in biochemistry. Spring. Advisor for Bettye Ridley.
Research in biochemistry. Summer. Advisor for Bettye Ridley, Chifu Huang,
and Allen Schroering.
1990-1991
BCH618:
Seminar in biochemistry. Fall. Advisor for Michael Shoemaker. (13 hours class
time, 5-7 hours advising).
BCH615:
Molecular biology and genetics. Spring. 12 hours of lecture/discussion (eight 1.5
hour sessions, 20-30 students).
Seminar in biochemistry. Spring. 13 hours class time; 10-14 hours advising.
Advisor for Titania Nugroho and Reichang Yan.
Research in biochemistry. Spring. Advisor for Wensheng Lin.
BCH619:
BCH640:
BCH640:
Research in biochemistry. Summer. Advisor for Wensheng Lin and Scott
Walker.
Michael Mendenhall
3
1991-1992
BCH618:
BCH640:
BCH615:
BCH619:
BCH640:
BCH780:
BCH517:
BCH640:
Seminar in biochemistry. Fall. (13 hours class time, 5-7 hours advising).
Advisor for Michael Shoemaker.
Research in biochemistry. Fall. Advisor for Jiu-sheng Wu, Scott Walker, and
Wensheng Lin.
Molecular biology and genetics. Spring. 4.5 hours of lecture/discussion (three
1.5 hour sessions, 20-30 students)
Seminar in biochemistry. Spring. (9 hours class time; 5-7 hours advising).
Advisor for Cancan Huang.
Research in biochemistry. Advisor for Scott Walker and Wensheng Lin.
Topics in biochemistry (research proposal writing). Spring. Advisor for Titania
Nugroho and Scott Walker.
Experimental methods in biochemistry (laboratory course for 12 graduate
students, 160 contact hours). Summer. Course director.
Research in biochemistry. Summer. Advisor for Wensheng Lin and Titania
Nugroho.
1992-1993
BCH611:
BCH618:
BCH749:
BCH615:
Biochemistry and cell biology of nucleic acids. Fall. (7.5 hours class time, 17
students)
Seminar in biochemistry. Fall. (10 hours class time).
Dissertation research. Fall. Advisor for Wensheng Lin and Titania Nugroho.
BCH749:
Molecular biology and genetics. Spring. 4.5 hours of lecture/discussion (three
1.5 hour sessions, 20-30 students)
Seminar in biochemistry. Spring. Advisor for Titania Nugroho. (9 hours class
time).
Biochemistry for Medical Students. Spring. 3 hours class time. 6 hours
preparation time. Led small group (12-15 students) discussion of papers taken
from the scientific literature.
Dissertation research. Spring. Advisor for Wensheng Lin and Titania Nugroho.
BCH749:
BCH850:
Dissertation research. Summer. Advisor for Titania Nugroho.
Fourth-year elective for medical students. Summer. Advisor for Yvon Sterkers.
BCH619:
BCH811:
1993-1994
BCH401G:
BCH618:
BCH640:
BCH749:
Fundamentals of biochemistry (undergraduate and graduate introductory course,
16 one hour lectures, 153 students). Fall.
Seminar in biochemistry. Fall. (9 hours class time, 5-7 hours advising). Advisor
for Dequin Ma.
Research in biochemistry. Fall. Advisor for Jianming Yin.
Dissertation research. Fall. Advisor for Titania Nugroho and Cancan Huang.
Michael Mendenhall
4
BCH615:
BCH749:
Molecular biology and genetics. Spring. 4.5 hours of lecture/discussion (three
1.5 hour sessions, 20-30 students)
Seminar in biochemistry. Spring. (9 hours class time; 5-7 hours advising).
Advisor for Kenneth Henry.
Dissertation research. Spring. Advisor for Titania Nugroho.
BCH749:
Dissertation research. Summer. Advisor for Titania Nugroho.
BCH619:
1994-1995
MI707
BCH401G:
BCH640:
BCH749:
BCH619:
BCH615:
BCH401G:
BCH618:
BCH749:
BCH619:
BCH615:
BCH401G:
BCH618:
BCH640:
BCH619:
BCH401G:
BCH618:
BCH619:
BCH401G:
BCH618:
BCH619:
BCH780:
Special topics in Molecular Biology: Cell cycle regulation. Fall. Mentor for Amy
Dix's presentation on Inhibitors of cyclin dependent kinases.
Fundamentals of biochemistry (undergraduate and graduate introductory course,
17 one hour lectures, 200 students). Fall. Course director.
Research in biochemistry. Fall. Advisor for Paula Lemons.
Dissertation research. Fall & spring. Advisor for Titania Nugroho.
Seminar in biochemistry. Spring. (9 hours class time).
Molecular biology and genetics. Spring. 4.5 hours of lecture/discussion (three
1.5 hour sessions, 30 students)
1994-1995
Fundamentals of biochemistry (undergraduate and graduate introductory course,
17 one hour lectures, 200 students). Fall. Course director.
Seminar in biochemistry. Fall. (9 hours class time).
Dissertation research. Fall & spring. Advisor for Titania Nugroho.
Seminar in biochemistry. Spring. (9 hours class time).
Molecular biology and genetics. Spring. 4.5 hours of lecture/discussion (three
1.5 hour sessions, 30 students)
1995-1996
Fundamentals of biochemistry (undergraduate and graduate introductory course,
17 one hour lectures, 200 students). Fall. Course director.
Seminar in biochemistry. Fall. (9 hours class time).
Research in biochemistry. Fall. Advisor for William Howard.
Seminar in biochemistry. Spring (9 hours class time).
1996-1997
Fundamentals of biochemistry (undergraduate and graduate introductory course,
17 one hour lectures, 200 students). Fall. Course director.
Seminar in biochemistry. Fall. (9 hours class time).
Seminar in biochemistry. Spring (9 hours class time).
1997-1998
Fundamentals of biochemistry (undergraduate and graduate introductory course,
23 one hour lectures, 200 students). Fall. Course director.
Seminar in biochemistry. Fall. (9 hours class time).
Seminar in biochemistry. Spring (9 hours class time).
Signal Transduction. Spring (4.5 hours class time).
Michael Mendenhall
5
BCH401G:
BCH618:
BCH619:
BCH401G
BIO632
BCH618:
BCH619:
BCH608
1998-1999
Fundamentals of biochemistry (undergraduate and graduate introductory course,
23 one hour lectures, 200 students). Fall. Course director.
Seminar in biochemistry. Fall. (9 hours class time).
Seminar in biochemistry. Spring (9 hours class time).
1999-2000
Fundamentals of biochemistry (undergraduate and graduate introductory course,
200 students). Fall. Course director.
Cell Division (22 lecture hours, 12 students). Fall.
Seminar in biochemistry. Fall. (9 hours class time).
Seminar in biochemistry. Spring (9 hours class time).
Biochemistry (8 lectures, 50 students). Spring.
IBS603
IBS605
BCH618:
BCH619:
IBS602
2000-2001
Fundamentals of biochemistry (undergraduate and graduate introductory course,
200 students). Fall. Course director.
Cell Biology & Signaling I. Fall. 5 lectures.
Experimental Genetics. Fall. 5 lectures.
Seminar in biochemistry. Fall. (9 hours class time).
Seminar in biochemistry. Spring (9 hours class time).
Biomolecules & Molecular Biology. Spring. 2 lectures.
BCH618:
BCH619:
IBS602
2001-2002
Seminar in biochemistry. Fall. (9 hours class time).
Seminar in biochemistry. Spring (9 hours class time).
Biomolecules & Molecular Biology. Spring. 1 lecture.
IBS601
BCH618:
BCH619:
2002-2003
Biomolecules. Fall (7 lectures)
Seminar in biochemistry. Fall. (9 hours class time).
Seminar in biochemistry. Spring (13 hours class time, advisor for Shuangli Guo).
BCH401G
IBS602
IBS601
BCH611
BCH618:
BCH619:
MI616
IBS601
BCH611
BCH618:
BCH619
2003-2004
Biomolecules II. Spring (1 lecture)
Biomolecules. Fall (course director, 9 lectures)
Nucleic Acids. Fall (5 lectures)
Seminar in biochemistry. Fall. (15 hours class time, advisor for Garland
Crawford).
Seminar in biochemistry. Spring (15 hours class time)
2004-2005
Cancer. Spring (1 lecture)
Biomolecules. Fall (course director, 10 lectures)
Nucleic Acids. Fall (5 lectures)
Seminar in biochemistry. Fall. (15 hours class time, advisor for Rachel
Schowalter & Jianing Yang).
Seminar in Biochemistry. Spring. (15 hours class time)
Michael Mendenhall
6
2005-2006
IBS601
BCH618
BCH619
Biomolecules: Fall (course director, 15 lectures)
Seminar in Biochemistry. Fall (15 hours class time)
Seminar in Biochemistry: Spring (15 hours class time)
2006-2007
MI616
BCH619
BS601
BCH618
Cancer. Spring (1 lecture)
Seminar in Biochemistry: Spring (15 hours class time)
Biomolecules: Fall (course director, 18 lectures)
Seminar in Biochemistry. Fall (15 hours class time)
2007-2008
BCH619
IBS601
BCH618
Seminar in Biochemistry: Spring (15 hours class time)
Biomolecules: Fall (course director, 18 lectures)
Seminar in Biochemistry. Fall (15 hours class time, advisor for Chunxia Zhao)
2008-2009
BCH619
IBS601
BCH618
MI616
Seminar in Biochemistry: Spring (15 hours class time)
Biomolecules: Fall (course director, 18 lectures)
Seminar in Biochemistry. Fall (15 hours class time)
Cancer. Spring (2 lectures)
2009-2010
BCH619
IBS601
BCH618
Seminar in Biochemistry: Spring (15 hours class time)
Biomolecules: Fall (course director, 18 lectures, 16 discussion sections)
Seminar in Biochemistry. Fall (15 hours class time)
2010-2011
BCH619
IBS601
BCH618
Bioethics
Seminar in Biochemistry: Spring (15 hours class time)
Biomolecules: Fall (course director, 18 lectures, 16 discussion sections)
Seminar in Biochemistry. Fall (15 hours class time)
Led 30 minute discussion section on laboratory animal use
2011-2012
BCH619
IBS601
BCH618
Seminar in Biochemistry: Spring (15 hours class time)
Biomolecules: Fall (course director, 18 lectures, 16 discussion sections)
Seminar in Biochemistry. Fall (15 hours class time)
2012-2013
BCH619
Seminar in Biochemistry: Spring (15 hours class time)
Michael Mendenhall
7
IBS601
BCH401G
BCH618
Biomolecules: Fall (course director, 18 lectures, 16 discussion sections)
Introduction to Biochemistry (3 lectures)
Seminar in Biochemistry. Fall (15 hours class time)
Student Research Advising
Masters student: Wensheng Lin (Jan 1991-Dec 1992)
Ph.D. students: Titania Nugroho (Aug 1991-July 1995)
Brett Johnson (June 1998-1999)
Kirk Williams (Jan 2000-2001)
Postdoctoral advisor:
Walid Al-Jumaily (Sept 1992-July 1995)
R. Michael Sheetz (Sept 1993-June 1994)
Gopalakrishnan Venkataraman (April 1995-February 1996)
Keith Filer (July 1995-1998)
Qing-hua Chin (Oct 1996-2003)
Jennifer Williams (Oct 1997-2000)
Yu Xue-yan (Dec. 1999-Nov. 2000, May 2002-2003)
Student committees:
Sue Jamison (Biochemistry, Aug 1988-)
Bettye Ridley (Biochemistry, June 1989-Aug 1990)
Michael Shoemaker (Biochemistry, June 1989-May 1994)
Shawn Lockhart (Biochemistry, Aug 1989-July 1993)
Scott Walker (Biochemistry, June 1991-June 1992)
Chin-ten Chen (Microbiology & Immunology, Aug 1991-Oct 1994)
Yi Li (Biology, July 1992-April 1996)
Jennnifer Williams (Biology, Apr 1993-1997)
Jennifer Myka (Vet science, 1994-2002)
Jianming Yin (Biochemistry, 1995-2000)
Christopher Lies (Biology, May 1995-2002)
Seyung Chung (Biology, March 1996-2000)
Haipeng Shao (Biochemistry, 1996-2000)
Srinivas Venkatram (Biology, 1996-1999)
Kareem Chehade (Biochemistry 1996-2002)
Paul Balbo (Microbiology 1998-2002)
Duane Hassane (Microbiology 1998-2002)
Brett Johnson (Biochemistry 1998-2004)
Mohammed Alanazi (Biochemistry 1999)
Kris Jones (Biochemistry 1999-2000)
C.K. Prakash (Biology 1999-2003)
Michael Spencer (Biochem 1999-2003)
Kirk Williams (Biochem 2000-2001)
Robert Bevins (MI 2002-2006)
Dissertation committees (outside reviewer):
Kevin Stansbury (Toxicology, 26 July 1994)
Michael Mendenhall
8
Melissa Dunn (Microbiology, 23 August 1995)
Kuang-Ren Chung (Plant Pathology, 5 March 1996)
Jijun Cheng (Biology, 2 December 1999)
Sakshi Pandit (Biology, 4 September 2007)
Tseten Yeshi (Biology, 2 December 2010)
Other advising
Yvonne Sterkers. Fourth year medical school elective (visiting student from Necker EnfantsMalades, Paris, France) 1993 summer
Brandon Rexford. Program in summer research for high school science teachers. Howard
Hughes Initiative (Lawrence Dunbar High, Lexington, KY). 1994 summer
Eustace Fernandes. Summer undergraduate research project (visiting student from the
University of Toledo, Toledo, Ohio) 1994 summer.
Matthew Cave: Summer undergraduate research project (visiting student from Rice
University, Texas) 1995 summer.
Crystal Randolph: Program in summer research for high school science teachers. Howard
Hughes Initiative. (Franklin High, Franklin, KY) 1995 summer
Doug Dietemeyer: Post-baccalaureate research. July 1995-July 1996
Fred Lin: Academic Mentoring Program, Henry Clay High School. September 1995-June
1996
Brett Glass: Academic Mentoring Program, Henry Clay High School. September 1995-June
1996
Amy Fliegge: Graduate student from Yale Department of Biochemistry (September 19961999)
Sarah Crowley: Howard Hughes Summer Undergraduate Research (1997)
Jeff Craig: Undergraduate honors project, Pfizer Award winner (1999)
Che-yun Brelin: Academic Mentoring Program, Dunbar High School, (September 1999-June
2000)
Yu Xueyan :Visiting Scientist from Shandong University, PRC (December 1999-Nov. 2000)
Yu Xueyan :Visiting Scientist from Shandong University, PRC (May 2002-April 2003)
Brandon Adkins: BIO395 student (Fall 2003-Spring 2005)
Jessica Own:
Berea Undergraduate (Summer, 2004)
Leslie Denhard:
Berea Undergraduate (Summer, 2004)
Jennifer Elmore:
Berea Undergraduate (Summer, 2005)
Jamie Johnson:
Berea Undergraduate (Summer, 2005)
Jason Meyer:
UK undergraduate (Fall 2006 to summer 2007 research project)
Grant Support
PRESENT
2009--
NIH 8P20GM103486-09 (COBRE): "Molecular Basis of Human Disease"
(Louis Hersh, PI);Oct. 1, 2009 topresent; 5% effort, Direct costs for July
2012 to June 2013: $133,462, Indirect costs for July 2012 to June 2013:
$64,729
Michael Mendenhall
9
.
PAST
2001-2002
2000-2001
1995-2000
1998
1988-1989
1988-1989
1989
1990-1991
1991
1990-1993
1993-1995
2001-2004
2003-2007
2009-present
NIH R21 AI48590-01: "Genetic analysis of C. jejuni CDT Function" (Carol
Pickett, PI);Oct. 1, 2001 to July 31, 2002; 5% effort, Total direct: 200,000
Total indirect: 89,600.
Medical Center Research Fund: "Factors Affecting the Interaction
Between a Cyclin Dependent Kinase and It's Inhibitor", July 2000 to 2001,
$15,000
National Institutes of Health, "Regulation of Sic1 inhibition of yeast Cdk
complexes" ($117,838 annual direct costs, PI)
Scope account ($15,000)
American Cancer Society Institutional Grant, "Phenotypic effects of
disruption of cell cycle controlled protein kinase/substrate interactions,"
$7,500 (P.I.)
UKMC Research Fund Small Research Project, "Identification of Cdc28
substrates," $10,000 (P.I.)
UKMC Major Equipment Grant, "Protein kinase substrates involved in cell
division control," $21,361.45 (P.I.)
Physicians Service Plan, "Molecular cloning of a cell cycle regulated
substrate of the Cdc28/Cdc2 protein kinase," $13,300 (P.I.)
UKMC Major Equipment Grant, "Major equipment purchase of centrifugal
elutriator," $20,470 (P.I.)
American Cancer Society, "The role of p40 in yeast cell division control,"
$90,000 annually (P.I.)
American Cancer Society, "The role of p40 in yeast cell division control"
($90,000 annually, P.I.).
DARPA CR-19108-430938 "The Eukaryotic Cell Cycle as a Test Case for
Modeling Cellular Regulation in a Collaborative Problem-Solving
Environment" (John Tyson, Va Tech, PI) Sept 1, 2001 to Aug 30, 2004,
10% effort, $1,650,000 total costs
NSF MCB-0315548 "Genetic and Biochemical Studies of a Yeast
CDK.inhibitor Interaction." (Michael Mendenhall, PI), 1 Sept 2003 to 30
August 2006 ($390,000 total costs)
NCRR 5P20RR020171-08 (Michael Mendenhall, co-PI; L. Hersh (PI) Viral
Core for the COBRE in the Molecular Basis of Human Disease,
09/01/04-06/30/14
Honors
1974-1975
1976-1978
1977
1978
1978-1981
1985-1988
14 June 1995
Alumni Scholar, University of California, Berkeley
Regents Scholar, University of California, Berkeley
Phi Beta Kappa
Graduated summa cum laude, University of California, Berkeley
NSF Predoctoral Fellowship
Jane Coffin Childs Postdoctoral Fellow
Hoechst-Stiftung Preis awarded for Schwob, E., T. Böhm, M.D.
Mendenhall & K. Nasmyth, (1994) The B-type cyclin kinase inhibitor
Michael Mendenhall
10
p40SIC1 controls the G1/S transition in Saccharomyces cerevisiae.
Cell 79:233-244
Professional Organizations
1988-present
1988-present
1988-present
1991-present
American Association for the Advancement of Science
American Society of Microbiologists
Genetics Society of America
American Society of Biochemistry and Molecular Biology
Presentations
Spring, 1989
2 November 1991
5 November 1992
12 May 1993
9 June 1993
16 September 1993
25 April 1994
13 September 1994
18 August 1994
20 August 1994
4 November 1994
14 November 1994
17 February 1995
30 March 1995
University of Kentucky, Department of Biological Sciences
University of Chicago, An inhibitor of CDC28.
University of Kentucky, Department of Biological Sciences,
Stopping the cell cycle? An inhibitor of the CDC28/cdc2 protein
kinase
The Cell Cycle '93: Regulators, Targets and Clinical Applications.
XIIIth Washington International Spring Symposium, George
Washington University School of Medicine. An inhibitor of the
Cdc28 protein kinase may mediate a cell cycle checkpoint.
1993 Yeast Genetics and Molecular Biology Meeting, University of
Wisconsin, Madison. An inhibitor of the Cdc28 protein kinase may
mediate a cell cycle checkpoint.
Professional education, American Cancer Society Board Meeting,
Lexington, KY.
Department of Microbiology and Molecular Biology, Oklahoma
State University. Stopping cell division: Genetic analysis of an
inhibitor of cyclin-dependent protein kinase from yeast.
Department of Microbiology & Immunology, University of Kentucky,
Lexington. The G1S transition in yeast.
1994 Yeast Genetics and Molecular Biology Meeting, University of
Washington, Seattle. SIC1 of S. cerevisiae is a cyclin-specific
inhibitor of Cdc28.
1994 Yeast Genetics and Molecular Biology Meeting, University of
Washington, Seattle. Panelist on workshop on cell cycle
regulation. Led discussion on inhibitors of cyclin dependent
kinases.
University of Chicago, Chicago, Illinois. STARTing S phase.
Department of Biochemistry and Molecular Biology, Indiana
University School of Medicine. The G1S transition in yeast.
NICHD NIH, Bethesda, MD. The START to S phase transition in
yeast.
Plenary session speaker at the Serono Symposia XIIIth Testis
Workshop: Cellular and Molecular Regulation of Testicular Cells.
Michael Mendenhall
11
27 April 1995
3 May 1995
11 January 1996
28 March 1996
22 November 1997
1 December 2000
March 2003
8 Nov 2008
From Start to S phase: Early regulatory events in the yeast cell
cycle.
Department of Biochemistry, University of Colorado, Denver. The
G1S transition in yeast
Banting and Best Department of Medical Research, University of
Toronto, Ontario, Canada. The role of Sic1 cyclin dependent
kinase inhibitor in the Start to S phase transition of yeast.
Keystone Symposia on The Cell Cycle: The Sic1 inhibitor of the
yeast G1/S transition.
Lousiana State University, Shreveport, LA.The Sic1 inhibitor of the
yeast G1/S transition.
University of Chicago, IL. Phosphorylation and ubiquitination of
the CDK inhibitor Sic1
Virginia Polytechnic University, Blacksburg, VA. Control and
maintenance of the G1 period in yeast
Kinetic studies of early cell cycle events in Saccharomyces
cerevisiae. Budapest Collegium, Budapest, Hungary.
Oral presentation: Proteomic analysis reveals Elongin C as a
mediator of Notch4 activity in renal tubule cells. American Society
of Nephrology Meeting in Philadelphia.
Service
Graduate student recruitment committee for the Department of Biochemistry from 1989 to
1992.
Preliminary examination coordinator, 1989-1994. I completely revamped the written
examination to focus on defined (but changing) topics that the students could focus. In
addition I have had the responsibility of organizing the exam every year.
Curriculum committee of the Department of Biochemistry, 1991.
Co-organizer (with Judith Shelling and Isabel Mellon) of the Junior Faculty Joint Research
talks designed to promote greater interactions among newly recruited faculty in the
Department of Biochemistry. 1992-1994.
Departmental seminar coordinator, 1993-1994
Macromolecular Structure Analysis Oversight Committe, 1993-1998
Research Committe of the College of Medicine, 1994 to 1995. Thomas Curry and I have had
the responsibility of rewriting the application guidelines to better serve the needs of the
local research community.
Organizer of the Cell Cycle Group, a monthly research presentation from laboratories on
campus that have a common interest in the mechanisms by which cells divide.
Participants include: Don Biek, Jeff Davidson, Jim Freeman, Neal Kay, Tim Meeker,
Pete Mirabito, Bin-Tao Pan, Tom Roszman, Jesse Sisken, Charlie Snow, Steve Zimmer
and their laboratories. 1993-1999. This meeting has already spawned several joint
research projects.
New Faculty Recruitment Committee (1994-1995)
Signal Tranduction & Cell Cycle Subcommittee for preparation of Cancer Center Core Grant
(1995-1996)
Program Director for the Cell Cycle and Proliferation Program (1996-1999)
Chair Combs Building Equipment Committee (1997-)
Michael Mendenhall
12
Senate Advisory Faculty Code Committee (alternate member, 1998-1999)
Director of Graduate Studies for the Department of Biochemistry (1998-2003)
Academic Council for the Medical Center (alternate member, 1 Sept 1998 to 31 August 2000)
New Biochemistry Faculty Recruitment (1998-99)
Biochemistry Curriculum committee (1998-)
co-Director of College of Medicine combined Masters of Science program (1999-2000)
Senate Advisory Faculty Code Committee (regular member, 1999-2001)
Review and Chair Search Committee for the Department of Behavioral Science (1999-2002)
Integrated Graduate Program Committee (1999-)
Academic Council for the Medical Center (regular member, 1 Sept 2000 to 31 Aug 2002)
Faculty Council for the Medical Center (2000 academic year)
Electronic Thesis and Dissertation Committee (2000-2002)
Behavioral Science Chair Search Committee (2000-2001)
Director of the Masters of Medical Science Program (2000-2001)
CCTS/CR-DOC Scientific Review Committee (2008-2011)
Director of the Viral Core Facility (2009-)
Institutional Biosafety Committee (2011-)
Vice Chair for Education, Department of Molecular & Cellular Biochemistry (2012-)
Director of Graduate Studies, Department of Molecular & Cellular Biochemistry (2012-)
MS Medical Sciences Oversight Committee (2012-)
Undergraduate Education Working Group (2012-2013)
Committee on Educational Productivity (2013)
Basic Science Subcommittee of the COM Curriculum Committee (2013-)
Senate Adhoc Committee on Teacher Course Evaluation (2014-)
COM Faculty Council (2014-)
Editorial Boards
Journal of Biological Science (1998-2003)
Journal/Grant/Text Reviews
BRSG/PSP grant, 1989, 1992.
National Science Foundation ad hoc reviews (1994-5, 2005, 2007, 2009)
NSF Study Section Member: Signal Transduction and Regulation (1995-1998, 2001-2004,
2006-2007)
Louisiana Education Quality Support Fund (1995)
Genetics (1999-2002)
Genes & Development (2005, 2006)
Journal of Biological Chemistry (1994-1998, 2004-2007)
Journal of Cell Science (2000)
Molecular & Cellular Biology (1995, 2006)
Molecular and General Genomics (2001)
Molecular Biology of the Cell (1995)
Proceedings of the National Academy of Science (1996)
New Biochemistry Text designed for a 1 semester introductory course from Harper Collins
Publishers (1995)
Michael Mendenhall
13
Local American Cancer Society (1995)
National American Cancer Society (1996)
NIH ad hoc (1998)
University of Kentucky Medical Center Research Fund (1997, 1998)
Chaired site visit for NSF Plant Genome Program @ University of Missouri, Columbia (1-3
June 1999)
New edition of Biochemistry by Voet & Voet (2000)
South Plains Foundation (2001)
NIH Study Section Member. Minority & Disabled Post-doctoral Fellowships (2002-2005)
MU-Monsanto Project Proposal (2002)
Military Infectious Disease Research Program (2002)
Pre-revision review of chapters in Biochemistry by Berg, Timockyo & Stryver (2009)
Tenure review for Department of Biochemistry & Cellular & Molecular Biology at the University
of Tenneesse (2009)
Markey Cancer Center internal grant (2009)
NSF ad hoc review (2010)
Chapter reviews of new edition of Lehninger’s Principles of Biochemistry by Nelson & Cox
(2011)
Proposal reviewer for Shota Rustaveli National Science Foundation (Georgia): (2011-)
National Science Foundation Fellowship Program Study Section (2013)
Chapter reviews of new edition of Berg, Tymoczko & Styer Biochemistry by Freeman (2013)
Publications
Reed, S.I., de Barros-Lopes, M.A., Ferguson, J., Hadwiger, J.A., Ho, J., Horwitz, R., Jones,
C.A., Lörincz, A.T., Mendenhall, M.D., Peterson, T.A., Richardson, S., and Wittenberg,
C. (1985) Genetic and molecular analysis of division control in yeast. Cold Spring
Harbor Symposia on Quantitative Biology, v. L pp. 627-634. Cold Spring Harbor
Laboratory, Cold Spring Harbor, N.Y.
Winey, M., Mendenhall, M.D., Cummins, C.M., Culbertson, M.R., and Knapp, G. (1986)
Splicing of a yeast proline tRNA containing a novel suppressor mutation in the
anticodon stem. J. Mol. Biol. 192:49-63
Mendenhall, M.D., Leeds, P., Fen, H., Mathison, L., Zwick, M., Sleiziz, C., and Culbertson,
M.R. (1987) Frameshift suppressor mutations affecting the major glycine transfer RNAs
of Saccharomyces cerevisiae. J. Mol. Biol. 194: 41-58
Mendenhall, M.D., Jones, C.A., and Reed, S.I. (1987) Dual regulation of the yeast CDC28-p40
protein kinase complex: Cell cycle, pheromone, and nutrient limitation effects. Cell
50:927-935
Mendenhall, M.D. and Culbertson, M.R. (1988) The yeast SUF3 frameshift suppressor
encodes a mutant glycine tRNAccc. Nuc. Acids Res. 16:8712
Ball, C.B., Mendenhall, M.D., Sandbaken, M.G., and Culbertson, M.R. (1988) The yeast SUF5
frameshift suppressor encodes a mutant glycine tRNAccc. Nuc. Acids Res. 16:8713
Mendenhall, M.D., Richardson, H.E., and Reed, S.I. (1988) Dominant negative protein kinase
mutations that confer a G1 arrest phenotype. Proc. Natl. Acad. Sci. USA 85:44264430
Reed, S.I., Hadwiger, J.A., Mendenhall, M.D., Richardson, H.E. and Wittenberg, C. (1988)
Control of cell proliferation in Saccharomyces cerevisiae by the Cdc28 protein kinase.
In Current Communications in Molecular Biology: Cell Cycle Control in
Michael Mendenhall
14
Eukaryotes. Beach, D., Basilico, C. and Newport J., eds. pp.53-56. Cold Spring
Harbor Laboratory, Cold Spring Harbor, N.Y.
Reed, S.I., Hadwiger, J.A., Mendenhall, M.D., and Wittenberg, C. (1988) Regulation of cell
division in yeast by the Cdc28 protein kinase. In Cancer Cells/6 Eukaryotic DNA
Replication. Edited by T. Kelly and B. Stillman. pp. 251-258. Cold Spring Harbor
Laboratory, Cold Spring Harbor, N.Y.
Hadwiger, J.A., Wittenberg, C., Mendenhall, M.D., and Reed, S.I. (1989) The Saccharomyces
cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene,
encodes a subunit of the Cdc28 protein kinase complex. Mol. Cell. Biol. 9:2034-2041
Mendenhall, M.D. (1993) An inhibitor of p34CDC28/cdc2 protein kinase activity from
Saccharomyces cerevisiae. Science 259:216-219
Nugroho, T.T. and M.D. Mendenhall (1994) An inhibitor of yeast cyclin-dependent protein
kinase plays an important role ensuring the genomic integrity of daughter cells, Mol.
Cell Biol. 14:3320-3328
Schwob, E., T. Böhm, M.D. Mendenhall and K. Nasmyth (1994) The B-type cyclin kinase
inhibitor p40SIC1 controls the G1/S transition in Saccharomyces cerevisiae. Cell 79:233244
Mendenhall, M.D., W. Al-jumaily, & T.T. Nugroho (1995) The Cdc28 inhibitor p40 SIC1. In
Progress in Cell Cycle Research. v. 1. Edited by L. Meijer and H.Y. Lim Tung. p.
173-185. El Tree Scientific Publishers, Houston, TX,
Mendenhall, M.D. (1996) From Start to S phase: Early regulatory events in the yeast cell cycle.
In Cellular and Molecular Regulation of Testicular Cells. Edited by Claude
Desjardins. p. 11-25. Springer-Verlag Inc. New York, NY
Mendenhall, M.D. The cyclin dependent kinase inhibitors of Saccharomyces cerevisiae and
Schizosaccharomyces pombe (1998) In Current Topics in Microbiology and
Immunology. P. 1-24 Edited by S.I. Reed and P. Vogt. Springer-Verlag New York, Inc.
Schneider, B. L., E. E. Patton, S. Lanker, M. D. Mendenhall, C. Wittenberg, B. Futcher, and M.
Tyers (1998) Yeast G1 cyclins are unstable in G1 phase. Nature 395:86-89 (1998).
Mendenhall, M.D. and A. E. Hodge (1998), Regulation of Cdc28 cyclin-dependent protein
kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae. Molecular
& Microbiological Reviews 62:1191-1243
Hodge, A. and M. Mendenhall (1999) The cyclin-dependent kinase inhibitory domain of the
yeast Sic1 protein is contained within the C-terminal 70 amino acids, Molecular &
General Genetics 262:55-64
Greenberg, V.L., J.M. Williams, E. Boghaert,M.D. Mendenhall, K. B. Ain, and S.G. Zimmer
(2001) Butyrate alters the expression and activity of cell cycle components in anaplastic
thyroid carcinoma cells, Thyroid 11:21-29
Greenberg, V.L., J.M. Williams, J.P. Cogswell, M.D. Mendenhall, and S.G. Zimmer, (2001)
Histone deacetylase inhibitors promote apoptosis and differential cell cycle arrest in
anaplastic thyroid cancer cells, Thyroid 11:315-325
Hassane, D. C., R. B. Lee, M. D. Mendenhall, and C. L. Pickett (2001) Cytolethal distending
toxin demonstrates genotoxic activity in a yeast model, Infection and Immunity
69:5752-9.
Nash, P., X. Tang, S. Orlicky, Q. Chen, F. B. Gertler, M.D. Mendenhall, F. Sicheri, T. Pawson,
M. Tyers (2001) Multisite phosphorylation of a CDK inhibitor sets a threshold for the
onset of DNA replication. Nature 414: 514-521.
Timothy D. Cummins, Michael D. Mendenhall, Michelle N. Lowry, Erik A.Korte, Michelle T.
Barati, Syed J. Khundmiri, Sarah A. Salyer, Jon B. Klein, David W. Powell (2011) Elongin
Michael Mendenhall
15
C is a Mediator of Notch4 Activity in Human Renal Tubule Cells, BBA - Proteins and
Proteomics 1814:1748-1757
Erica M. Weekman, Tiffany L. Sudduth, Erin L. Abner, Gabriel J. Popa, Michael D. Mendenhall,
Holly M. Brothers, Kaitlyn Braun, Abigail Greenstein and Donna Wilcock (2014)
Transition from an M1 to a mixed neuroinflammatory phenotype increases amyloid
deposition in APP/PS1 transgenic mice. J. of Neuroinflammation 11:127.
Books
Signal Transduction Protocols, 2nd Edition (2004) edited by Robert C. Dickson and Michael D.
Mendenhall, Humana Press.