RIME - Sore Throat Kevin Chang, MSIII November 26, 2010 History Intake Duration, severity, improving/worsening Onset (abrupt or gradual) Respiratory distress / difficulty breathing Fever (how high, how long, getting better or worse) Fatigue Immunization history (important for C. diphtheria) Physical Exam Mucosal injection / Erythema Exudates / Swelling Stridor / Drooling Vesicles / Lesions Asymmetry of tonsils / Deviation of uvula Differential Diagnosis of and Management Causes Pharyngitis- Viral Pharyngitis- Bacterial Abscess- Bacterial -Rhinovirus, coronavirus, RSV, adenovirus, coxsackie A, influenza, parainfluenza -Group A Streptococcus, Corynebacterium diphteriae, Neisseria gonorrhea, Chlamydia pneumoniae, Mycoplasma pneumoniae -Retropharyngeal, Lateral pharyngeal, Peritonsillar -EBV (infectious mononucleosis) Symptoms And Signs -Sore throat, difficulty speaking, difficulty swallowing, neck tenderness / swollen lymph nodes, fever, headache -Adenovirus: pharyngoconjunctival fever -Coxsackie: herpangina, hand/foot/mouth -EBV: excessive fatigue, chronic duration, lymphadenopathy, splenomegaly Treatment -Self limited, tx symptomatic - acetaminophen, NSAIDs (no aspirin) - warm liquids (honey/lemon tea) -gargle with warm salt water -throat lozenges (not in young children) -Sore throat, difficulty speaking, difficulty swallowing, neck tenderness / swollen lymph nodes, fever, headache *Note: Mostly indistinguishable from viral sx, though may have a more prolonged course or purulent exudate)* -Rapid strep test, if normal, then throat culture -For GAS: -10 day course of oral penicillin -OR single dose IM benzathine penicillin G -Group A Strep, Staph aureus, respiratory anaerobes, Haemophilus -Difficulty swallowing, drooling, unwillingness to move neck (torticollis), change in voice, respiratory distress, neck swelling/mass, trismus Other Conditions Epiglottitis Inflammatory conditions: Kawasaki’s disease, StevenJohnson syndrome, Behcet’s syndrome Chemical exposure Irritative pharyngitis (dry heat) Foreign body HSV (herpetic stomatitis) -Antibiotics (empiric until culture results), eg. Augmentin, clindamycin - Surgical drainage Sources: Nelson Textbook of Pediatrics, AAP Pediatrics in Review, UpToDate