CURRICULUM VITAE SOHEIL NAJIBI, M.D., Ph.D. EDUCATION College of Marin University of California, Berkeley Boston University School of Medicine Boston University School of Medicine Boston University School of Medicine Boston University School of Medicine University of Iowa Hip and Pelvis Institute (Joel M Matta) 1986-1989 1989-1990 1990-1995 1990-1997 1997-1998 1998-2002 2002-2003 2008-2009 B.A. Ph.D. M.D. Internship Residency Fellowship Fellowship Molecular Cell Biology Physiology Medicine General Surgery Orthopaedic Surgery Sports Medicine Pelvic and Acetabular Trauma Anterior Total Hip Reconstruction LICENSING Full License in state of Massachusetts, #205486 (expired) Full License in state of Iowa, #34524 (current) Full License in state of Michigan, #4301082734 (current) Full License in state of Arizona, # 33241 (current) Full License in state of California, # A88147 (current) Full License in state of Nevada, # 11120(current) Full License in state of Alaska #7256 (current) DEA #BN6947355 NPI # 1215003686 CERTIFICATION USMLE Part I USMLE Part II USMLE Part III Orthopaedic Surgery Written Boards Orthopaedic Surgery Oral Boards Diplomat, American Board of Orthopaedics Passed 1996 Passed 1997 Passed 1999 Passed 2002 Passed 7/28/06 July 28, 2006 – December 31, 2016 AFFILIATIONS American Academy of Orthopaedic Surgery, Fellow American Orthopaedic Society of Sports Medicine, Member Orthopaedic Trauma Association, Member CLINICAL APPOINTMENTS Head team physician, Men’s Ice Hockey, Wentworth Institute of Technology, Boston, Massachusetts, 2001-2002 Fellow team physician, Football, University of Iowa, Iowa City, Iowa, 2002 Fellow team physician, Basketball, University of Iowa, Iowa City, Iowa, 2002-2003 Fellow team physician, Men’s and Women’s Gymnastics, University of Iowa, Iowa City, Iowa, 2003 Senior Staff Surgeon, Department of Orthopedics, Henry Ford Hospital, Detroit, Michigan, 2003-2008 Head team physician, Motor City Mechanics, Professional Hockey (UHL) team, Michigan, 2004-2005 Associate Orthopaedic Residency Director, Henry Ford Health Systems, Detroit, Michigan, 2006- 2008 Hip and Pelvis Fellow, Saint John’s Hospital, Santa Monica, California, 2008-2009 Staff Surgeon, Hip and Pelvis Institute, Saint John’s Hospital, Santa Monica, California, August 2009- 2011 Staff Surgeon, Providence Alaska Medical Center and Alaska Regional Hospital, Anchorage, Alaska, November 2011-2012 Director of Pelvis and Acetabular Trauma, Harbor UCLA, Torrance, California, August 2009-present RESEARCH INTERESTS Effects of nitric oxide on fracture healing, cartilage and ligament injury Epidemiology of non-military gunshot wounds in the musculoskeletal system Anterior Cruciate ligament allograft biomechanical testing Effects of Bone-morphogenic proteins on bone healing in large defects Wear characteristics of bearing materials in total hip arthroplasty CLINICAL INTERESTS Sports Medicine: Arthroscopic and open shoulder reconstruction, shoulder arthroplasty; arthroscopic and open knee ligamentous reconstruction, and cartilage procedures including OATS, OCT and osteochondral allografts; knee osteotomies and limb deformity correction. Orthopaedic Trauma: Pelvic and acetabular reconstruction. Fracture care. Management of poly-trauma patients. Management of gunshot wounds to the extremities. Management of articular and peri-articular fractures, knee dislocations and fracture dislocations. Shoulder fractures and fracture dislocations. Reconstruction: Anterior approach total hip arthroplasty. Peri-acetabular osteotomies. Shoulder arthroplasty. ORTHOPAEDIC COURSES AND MEETINGS 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. AO Basic Fracture Course, Charlotte, NC 1998 Boston Orthopaedic Trauma Symposium 1999 Boston Orthopaedic Pathology Course 1999 Boston Orthopaedic Trauma Symposium 2000 Boston Orthopaedic Trauma Symposium 2001 AAOS 17th Annual Comprehensive Review Course March 2001 New England Resident’s Spine Symposium 2001 Zimmer National Orthopaedic Resident Meeting 2001 Boston Orthopaedic Pathology Course 2002 Maine Comprehensive Orthopaedic Review Course 2002 AAOS 69th Annual Meeting, Dallas, TX 2002 AAOS 70th Annual Meeting, New Orleans, LA 2003 AAOS 71st Annual Meeting, San Francisco, CA 2004 Taylor Spatial Frame and Ring External Fixation Course, Columbus, OH 2004 Current Solutions in Orthopaedic Trauma, Tampa, FL Nov 2004 Advances in Locked Plating, Birmingham, MI March 2005 AOSSM Annual Meeting, Keystone Colorado July 2005 AAOS 73rd Annual Meeting, San Diego, CA 2006 Osteoarthritis Symposium, Dearborn, MI April 2006 AAOS/ASES: Completing the transition from open to arthroscopic rotator cuff tears, Los Angeles,CA 2006 Boston Orthopaedic Trauma Symposium 2006 Reverse Shoulder Prosthesis Course, Tornier, Boston 2007 Orthopaedic Trauma Association, Boston 2007 Henry Ford Sports Medicine Symposium, Dearborn , MI 2008 AAOS 75th Annual Meeting, San Francisco, CA 2008 AO Fourteenth Pelvic and Acetabular Fracture Management Course, Toronto, Canada May 1-4, 2008 AOSSM Annual Meeting, Orlando, FL July 2008 20th Emile Letournel Institute Course and Workshop: Fractures of the Acetabulum and Pelvis, Santa Monica, CA September 2008 29. Orthopaedic Trauma Association, Denver, CO October 2008 30. Orthopaedic Trauma Association, San Diego, CA October 2009 31. 32. 33. 34. 35. 36. 37. Acumed Upper Extremity course, Las Vegas, NV November 2009 AAOS 77th Annual Meeting, San Diego, CA 2011 AOSSM Annual Meeting, San Diego, CA July 2011 Smith and Nephew anterior total hip arthroplasty and knee arthroplasty, Las Vegas, NV, September 2011 Orthopaedic Trauma Association Annual Meeting, San Antonio, TX, October 2011 Alaska Orthopaedic Society Meeting, Girdwood, AK, March 2012 AAOS 78th Annual Meeting, Chicago 2013 RESEARCH EXPERIENCE Hip and Pelvis Institute 08/08 to 08/09 Several projects involving the management and outcomes of pelvic and acetabular fractures, technique and outcomes of anterior approach total hip arthroplasty and resurfacing. Henry Ford Health Systems 10/03 to 08/08 Department of Orthopaedic Surgery Several projects involving the epidemiology of extremity gunshot wounds, prevalence of gunshot wounds to the joints, biomechanical studies on fixation of olecranon with FiberWire tension band, biomechanical studies of load to failure of multiple tissue grafts used for ACL reconstruction, and study of risk factors influencing simultaneous bilateral extensor mechanism rupture, and a study of bone healing in opening wedge osteotomies with use of pone morphogeneic protein. Boston Medical Center and Lahey Clinic 7/98 to 6/02 Department of Orthopaedic Surgery Three projects involving the efficacy of non-reamed tibial nailing in tibial fractures, efficacy and feasibility of allpolyethylene tibial components in total knee arthroplasty, pros and cons of foley catheter utilization in total joint arthroplasty were studied. Boston University School of Medicine 5/92 to 9/95 Department of Physiology and Vascular Biology Several projects involving endothelium-dependent relaxation in normal and hypercholesterolemic rabbit arteries, as well as mechanisms of vascular smooth muscle contraction were studied. Boston University School of Medicine 5/91 to 8/91 Department of Physiology and Vascular Biology The effects of extracellular matrix on endothelial cell attachment and growth in cell cultures were studied. The effects of fibronectin and laminin on the rate of growth and differentiation of endothelial cells were investigated in the cell culture model. University of California, Berkeley 9/89 to 5/90 Department of Molecular Cell Biology Senior honors research project at U.C. Berkeley. The effects of L-Propionylcarnitine on myocardial ischemia and reperfusion injury were studied in the isolated Langandorff rat heart. College of Marin 2/88 to 6/88 Department of Chemistry Design of a multistep purification process to reclaim silver from heavy metal waste. DOCTORATE THESIS Regulation of vascular smooth muscle tone via endothelium-derived nitric oxide via two distinct mechanisms. PUBLICATIONS 1. Leipala JA, Bhatnagar R, Pineda E, Najibi S, Massoumi K and Packer L: Protection of the Reperfused Heart by L-propionylcarnitine. J. Appl. Physiol. 1991; 2471(4): 1518-1522. 2. Cowan CL, Palacino JJ, Najibi S and Cohen RA: Potassium Channel-Mediated Relaxation to Acetylcholine in Rabbit Arteries. J. Pharmacol. Exp. Ther. 1993; 266(3): 1482-1489. 3. Najibi S, Cowan CL, Palacino JJ and Cohen RA: Enhanced Role of Potassium Channels in Relaxations to Acetylcholine in Hypercholesterolemic Rabbit Carotid Arteries. Am. J. Phsiol. 1994; 266: H2061-H2067. 4. Bolotina VM, Najibi S, Palacino JJ, Pagano PJ and Cohen RA: Nitric Oxide Directly Activates Calciumdependent Potassium Channels in Vascular Smooth Muscle Cells. Nature 1994; 268: 850-853. 5. Stegeman JJ, Hahn ME, Weisbrod R, Woodin BR, Joy JS, Najibi S and Cohen RA: Induction of Cytochrome P4501A1 by Aryl Hydrocarbon Receptor Agonist in Porcine Aorta Endothelial Cells in Culture and Cytochrome P4501A1 Activity in Intact Cells. Mol. Pharmacol 1995; 47:296-306. 6. Najibi S and Cohen RA: Enhanced Role of Potassium Channels in Relaxations of Hypercholesterolemic Rabbit Carotid Artery to Nitric Oxide and Sodium Nitroprusside. Am. J. Physiol 1995; 269: H805-811. 7. Cohen RA, Plane F, Najibi S, Huk I, Malinski T and Garland CJ: Nitric Oxide is the Mediator of Both Endothelium-Dependent Relaxation and Hyperpolarization of the Rabbit Carotid Artery. Proc Natl Acad Sci, April 1997, Physiology; Vol 94: 4193-4198. 8. Pagano PJ, Griswold MC, Najibi S, Marklund SL and Cohen RA. Resistance of Endothelium-dependent Relaxation to Elevation of O 2 levels in Rabbit Carotid Artery. Am J Physiol Heart Circ Physiol, 277: H2109H2114, 1999. 9. Najibi S, Scherl SA and Cramer KE: Pediatric Femur Fracture. J Ortho Trauma, 2000 Aug; 14(6):449-450. 10. Adachi T, Matsui R, Weisbrod RM, Najibi S and Cohen RA: Reduced Sacro/Endoplasmic Reticulum Ca2+ Uptake Activity can Account for the Reduced Response to NO but not Sodium Nitroprusside in Hypercholesterolemic Rabbit Aorta. Circulation, 2001; 104:1040-1045. 11. Bhandari M, Tornetta P 3rd, Sprague S, Najibi S, Petrisor B, Griffith L and Guyatt GH: Predictors of Reoperation following Operative Management of Fractures of the Tibial Shaft. J Ortho Trauma. 2003 May; 17(5):353-61. 12. Najibi S, Iorio R, Surdam JW, Whang W, Appleby D and Healy WL: All-Polyethylene and Metal-Backed Tibial Components in Total Knee Arthroplasty: A Matched Pair Analysis of Functional Outcome. J Arthroplasty. 2003 Oct; 18(17 Suppl 1): 9-15. 13. Najibi S, Hartigan BJ and Goldfarb CA. Case Controversy, Distal Radius. J Ortho Trauma, 2004 April; 18(4): 250-252. 14. Iorio R, Whang W, Healy WL, Patch DA, Najibi S and Appleby D. The Utility of Bladder Catheterization in Total Hip Arthroplasty. Clin Orthop Relat Res. March 2005; 432: 148-52. 15. Najibi S and Albright JP. The use of knee braces, part 1: Prophylactic Knee Braces in Contact Sports. Am J Sports Med. 2005 April; 33(4):602-11. 16. Dougherty PJ, Silverton C and Najibi S. Urban Gunshot Wound Ballistics. Tech Ortho Trauma. 2006 Oct; 21(3):181-185. 17. Najibi S, Dougherty PJ and Morandi M. Management of Gunshot Wounds to the Joints. Tech Ortho Trauma. 2006 Sept; 21(3):200-204. 18. Dougherty PJ, Najibi S and Morandi M: Gunshot Humerus Shaft Fractures. Tech Ortho Trauma. 2006 Sept; 21(3):214-217. 19. Dougherty PJ, Vaidya R, Silverton CD, Bartlett C, and Najibi S. Joint and Long-Bone Gunshot Injuries. JBJS Am, 2009 April; 91:980-997. 20. Dougherty PJ, Najibi S, Silverton CD, Vaidya R. Gunshot Wounds: Epidemiology, Wound Ballistics, and Soft-Tissue Treatment. ICL 2009, 58:131-139. 21. Dougherty PJ, Van Holsbeeck M, Mayer TG, Garcia JA, and Najibi S. Lead Toxicity Associated with a Gunshot-Induced Femoral Fracture. A Case Report. JBJS Am, 2009 August; 91:2002-8. 22. Najibi S, Klenck RE, Matta JM, Tannast M. Symphyseal Disruption During Childbirth: Is Fixation Necessary? J Ortho Trauma, 2010 Dec;24(12):732-9. 23. Dougherty PJ, Walters N, Schilling P, Najibi S, Herkowitz H. Comparison of the USMLE Step 1, OITE, and ABOS Part I Certifying Examination Results: A Multicenter Study. Clin Orthop Relat Res. 2010 Mar 30. 24. Dougherty PJ, Vaidya R, Silverton CD, Bartlett CS, and Najibi S. Joint and Long-Bone Gunshot Injuries. Instr Course Lect, 2010; 59:465-79. 25. Najibi S, Banglmeier R, Matta JM, and Tannast M: Material Properties of Common Suture Materials in Orthopaedic Surgery. Iowa Orthopaedic Journal, 2010;30: 88-88. 26. Najibi S: Mechanical Failure of the Long Gamma Nail in Two Proximal Femur Fractures. Iowa Orthopaedic Journal, 2010; 30: 205-210. 27. Najibi S, Tannast M, and Latini JM. Civilian Gunshot Wounds to the Genitourinary Tract: Incidence, Anatomic Distribution, Associated Injuries and Outcomes. Urology, 2010 Oct;76(4):977-81; discussion 981. 28. Vaidya R, Sethi A, Najibi S, Lee S, and Dougherty PJ: Gunshot Injuries of the Spine, Evaluation and Management Principles. JAAOS. (in press) 29. Desai SS, Larkin BJ and Najibi S: Failed Distal Biceps Tendon Repair Utilizing a Single-Incision EndoButton Technique and Its Successful Treatment. A Case Report. J Hand Surg Am. 2010 Dec;35(12):1986-9. 30. Najibi S, Dougherty PJ , Matta JM. Tannast M. Gunshot Wounds to the Acetabulum: Pattern, Complications and Management. J Ortho Trauma. 2012 Aug;26(8):451-9. 31. Tannast M, Najibi S, Matta JM: 20-year Survivorship of the Hip Following Operative Treatment of 1208 Acetabular Fractures. JBJS Am. 2012 Sep 5;94(17):1559-67. 32. Elliot S. Mendelsohn, Tigor Warganich, Evan S. Nielson and Soheil Najibi: Application of an Antibiotic intramedullary Nail in the Management of Large Metacarpal Bone Defect. The Hand and Upper Extremity Surgery journal (in press) Book Chapters Richard A. Cohen, Soheil Najibi and Victoria Bolotina. The Other Role of Nitric Oxide as an Endothelium-Derived Hyperpolarizing Factor, 1995. Annunziato Amendola, Soheil Najibi. Foot and Ankle Injuries in Athletes. Orthopaedic Knowledge Update, Sports Medicine, Third Edition. Paul J. Dougherty, Soheil Najibi. Gunshot and wartime injuries. Rockwood and Green, Seventh Edition. Soheil Najibi, Joel M. Matta. Anterior Approach for Total Hip Arthroplasty. Orthopaedic Knowledge Update, Adult Reconstruction, Fourth Edition Soheil Najibi, Moritz Tannast, and Paul J. Dougherty, Section Editors. Chapter 7. Gunshot Wounds of the Joints. GUNSHOT WOUNDS, AAOS, Monograph Series 44. February 2011, ISBN/ISSN: 9780892037506. Soheil Najibi, Moritz Tannast, Paul J. Dougherty, and Jerilyn M. Latini, Section Editors. Chapter 10. Gunshot Wounds of the Pelvis and Acetabulum. GUNSHOT WOUNDS, AAOS, Monograph Series 44. February 2011, ISBN/ISSN: 9780892037506. Paul J. Dougherty and Soheil Najibi, Section Editors. Chapter 11. Gunshot Fractures of the Femoral Shaft. GUNSHOT WOUNDS, AAOS, Monograph Series 44. February 2011, ISBN/ISSN: 9780892037506. Paul J. Dougherty and Soheil Najibi, Section Editors. Chapter 12. Gunshot Fractures of the Tibia. GUNSHOT WOUNDS, AAOS, Monograph Series 44. February 2011, ISBN/ISSN: 9780892037506. Elliot S. Mendelsohn, Soheil Najibi and David J. Slutsky. Management of Traumatic Bone loss in the Hand. Operative Orthopedics: UpperExtremity, 1ed, Chapter 55, p 712-722. (in Press). ABSTRACTS and SCIENTIFIC MEETINGS 1. Soheil Najibi and Manaus Monroe. Reclamation of Silver from Heavy Metal Waste. 7th Annual Meeting of the Association of North Bay Scientists, Sonoma, CA 1987. 2. Conrad L. Cowan, James J. Palacino, Soheil Najibi, and Richard A. Cohen. Nitric Oxide-Independent Endothelium-Dependent Relaxation to Acetylcholine in Rabbit Arteries. FASEB #4436, 1993. 3. Soheil Najibi, Conrad L. Cowan and Richard A. Cohen. Hypercholesterolemia Enhances the Contribution of Calcium-dependent Potassium Channels to Endothelium-Dependent Relaxation in Rabbit Carotid Artery. American th Heart Association's 66 scientific session. Circulation 88(4), Part 2, #37, 1993. 4. Soheil Najibi and Richard A. Cohen. Nitric Oxide Inhibits Contractions due to Calcium Influx by a Potassium th Channel-Dependent Mechanism. American Heart Association's 67 scientific session. Circulation 90(4), Part 2,#1903, 1994. 5. Robert Weisbrod, Soheil Najibi, and Richard A. Cohen. Decreased Cyclic GMP-dependent Smooth Muscle Cell th Calcium Regulation by Nitric Oxide in Hypercholesterolemia. American Heart Association's 67 scientific session. Circulation 90(4), Part 2, #3100, 1994. 6. Soheil Najibi and Richard A. Cohen. Hypercholesterolemia Enhances Contribution of Calcium Activated Potassium Channels to Endothelium Independent Relaxation in Rabbit Carotid Artery. AFCR, 1995. 7. Soheil Najibi and Richard A. Cohen. Nitric Oxide Mediates Endothelium-Dependent Relaxation in the th Presence of Nitric Oxide Synthase Inhibitors Independently of Cyclic GMP. American Heart Association's 68 scientific session. Circulation 1995, 92(8), #2682. 8. P.J. Pagano, M.C. Griswold, Joseph Fiorillo, Soheil Najibi, and R.A Cohen. Resistance of EndotheliumDependent Relaxation to Superoxide Anion in the Rabbit Carotid Artery, Evidence for a Role of Peroxinitrite. Oxygen 95, Second Annual Meeting of the Oxygen Society 1995. 9. Soheil Najibi. Lasers in shoulder and knee surgery. 18th Annual Hawkeye Sports Medicine Symposium. University of Iowa; December 6-7, 2002. 10. Richard Iorio, Soheil Najibi, William Healy. All-Polyethylene and Metal-Backed Components in Total Knee Arthroplasty: a Matched Pair Analysis of Functional Outcome. AAOS 70 th Annual Meeting, P149, New Orleans, MO. 2003. 11. Soheil Najibi. Instructional Course Lectures, Treatment of Peri-Articular Gunshot Wounds. AAOS 74th Annual Meeting, San Diego, CA. 2007. 12. Soheil Najibi. Instructional Course Lectures, Treatment of Peri-Articular Gunshot Wounds. AAOS 75th Annual Meeting, San Francisco, CA. 2008 13. William Hakeos, Christopher Wybo, Shane A. Knighton, Paul Dougherty and Soheil Najibi. The Use of Fiber Wire Suture for Fixation of Olecranon Fractures: A Biomechanical Comparison of Various Fixation Techniques. Orthopaedic Trauma Association Annual Meeting, Denver, CO. 2008. 14. Soheil Najibi, Joel M. Matta, Moritz Tannast and Andrew Fishman Prevention of Thromboembolic Disease in Anterior Total Hip Arthroplasty with Acetylsalicylic Acid is Safe, Cost-Efficient and Effective. Chest Annual Meeting, San Diego, CA. 2009. 15. Soheil Najibi, Joel M. Matta, Paul J Dougherty, and Moritz Tannast. Gunshot Wounds to the Acetabulum: Pattern, Complications and Management. Orthopaedic Trauma Association Annual Meeting, San Diego, CA. 2009. 16. Soheil Najibi, Richard Banglmaier, Joel M. Matta and Moritz Tannast. Suture Materials in Orthopaedic Trauma: What is the Strongest? Orthopaedic Trauma Association Annual Meeting, San Diego, CA. 2009. 17. Moritz Tannast, Soheil Najibi, and Joel M. Matta. Long Term Survivorship of the Hip after Fixation of Acetabular Fractures. AAOS 76th Annual Meeting, New Orleans LA. 2010. 18. Soheil Najibi, Moritz Tannast and Jerilyn M. Latini. Civilian Gunshot Wounds to the Genitourinary Tract: Incidence, Anatomic Distribution, Associated Injuries and Outcomes. American Urologic Association 2011. AWARDS AND HONORS Life-time Member of Alpha Gamma Sigma Honor Society American Heart Association Medical Student Research Fellow of 1992-1993 Henry Russek Research Award 1995 American Federation of Research Council Scholarship 1995 Lahey Clinic Orthopaedic Research Award 2002 Detroit Academy of Orthopaedic Surgeons, Research Award, First Place, May 2008