Selected list of publications
Scientific papers (C. difficile)
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Rupnik M, Wilcox MH, Gerding DN. (2009) Clostridium difficile infection: new developments in
epidemiology and pathogenesis. Nat Rev Microbiol. 7(7):526-36. Review.
Zidaric V, Zemljic M, Janezic S, Kocuvan A, Rupnik M. (2008) High diversity of Clostridium difficile
genotypes isolated from a single poultry farm producing replacement laying hens. Anaerobe.
14(6):325-7.
Pokorn, M., Radšel, A., Čižman, M., Jereb, M., Karner, P., Kalan, G., Grosek, Š., Andlovic, A.,
Rupnik M. (2008) Severe Clostridium difficile associated disease in children. Pediatr Infect Dis J 27:
944-946.
Pirš T., Ocepek M., Rupnik M. (2008) Isolation of Clostridium difficile from food animals in Slovenia.
J. Med. Microbiol., 2008, vol. 57 (6): 790-792.
Rupnik M.
Heterogeneity of large clostridial toxins: importance of Clostridium difficile
toxinotypes.(2008) FEMS Microbiol Rev., 32(3): 541-555.
Rupnik M. Is Clostridium difficile-associated infection a potentially zoonotic and foodborne disease?
(editorial) (2007) Clin Microbiol Infect., 13:457- 459.
Reineke J, Tenzer S, Rupnik M, Koschinski A, Hasselmayer O, Schrattenholz A, Schild H, Von
Eichel-Streiber C. (2007) Autocatalytic cleavage of Clostridium difficile Toxin B. Nature, 446: 415419.
Greco A, Ho JG, Lin SJ, Palcic MM, Rupnik M, Ng KK. (2006) Carbohydrate recognition by
Clostridium difficile toxin A. Nat Struct Mol Biol., 13: 460-461.
Geric B, Carman RJ, Rupnik M, Genheimer CW, Sambol SP, Lyerly DM, Gerding DN, Johnson S.
(2006). Binary Toxin-Producing, Large Clostridial Toxin-Negative Clostridium difficile Strains Are
Enterotoxic but Do Not Cause Disease in Hamsters. J Infect Dis. 193(8):1143-50.
Ho, JG, Greco A, Rupnik M, Ng KK. (2005) Crystal structure of receptor-binding C-terminal repeats
from Clostridium difficile toxin A. Proc Natl Acad Sci U S A. 102:18373-8.
Rupnik, M., Dupuy, B., Fairweather, N.F., Gerding, D.N., Johnson, S., Just, I., Lyerly, D.M., Popoff,
M.R., Rood, J.I., Sonenshein, A.L., Thelestam, M., Wren, B.W., Wilkins, T.D., and Eichel-Streiber
C.v. (2005). Revised nomenclature of Clostridium difficile toxins and associated genes. J. Med.
Microbiol., 54: 113-117.
Rupnik, M., Pabst, S., Rupnik, M., von Eichel-Streiber, C., Urlaub, H., Soling H.D. (2005).
Characterization of the cleavage site and function of resulting cleavage fragments after limited
proteolysis of Clostridium difficile toxin B (TcdB) by host cells. Microbiology. 151: 199-208.
Rupnik, M., Grabnar, M., and Geric, B. (2003). Binary toxin producing Clostridium difficile strains.
Anaerobe, 9: 289-294.
Geric, B., Johnson, S., Gerding, D., Grabnar, M., and Rupnik, M. (2003). Frequency of binary toxin
genes among Clostridium difficile strains that do not produce large clostridial toxins. J. Clin.
Microbiol., 41: 5227-5232.
Rupnik, M., Avesani, V., Janc, M., Eichel-Streiber, C.v. and Delmée M. (1998) A novel toxinotyping
scheme and the correlation to serogrouping of Clostridium difficile isolates, J. Clin. Microbiol., 36:
2240-2247.
Scientific papers (general bacterioogy and microbial typing)
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Kotnik-Kevorkijan, B., Klasinc, M., Lorenčič Robnik, S., Petrovič, Ž., Rupnik, M.. (2009) Diversity
of spa types among MRSA isolates from Maribor University [SLO] Zdrav Vestn., 78, 119-122.
Rijavec T, Lapanje A, Dermastia M, Rupnik M. (2007) Isolation of bacterial endophytes from
germinated maize kernels. Can J Microbiol., 53(6):802-808.
Lapanje A, Drobne D, Nolde N, Valant J, Muscet B, Leser V, Rupnik M. (2007) Long-term Hg
pollution induced Hg tolerance in the terrestrial isopod Porcellio scaber (Isopoda, Crustacea). Environ
Pollut. 153:537-47
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Lapanje, A., Rupnik, M., Drobne, D. (2007) Gut Bacterial Community Structure (Porcellio Scaber,
Isopoda, Crustacea) As A Measure Of Community Level Response To Long-Term And Short-Term
Metal Pollution. Environ. Toxicol. Chem., 26, ( 4):. 755-763.
Cankar, K, Kraigher, H, Ravnikar, M, Rupnik, M. (2005). Bacterial endophytes from seeds of Norway
spruce (Picea abies L. Karst). FEMS Microbiol Lett., 244: 341-345.
Drobne, D., Rupnik, M., Lapanje, A., Strus, J. and Janc, M. (2002) Isopod gut microflora parameters
as endpoints in toxicity studies. Environ. Toxicol. Chem., 21: 604-609.
Book Chapters
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Rupnik M., Just I., (2006) Large clostridial cytotoxins modifying small GTPases. In Sourcebook of
Bacterial Protein Toxins (J. Alouf, M. Popoff, eds.), p.409- 429, Elsevier.
Kostanjšek, R., Štrus, J., Lapanje, A., Avguštin, G., Rupnik, M., Drobne, D. (2006) Intestinal
microbiota of terrestrial isopods. V: König, H., Varma, A. (eds.). Intestinal microorganisms of termites
and other invertebrates, (Soil biology, 6). Berlin: Springer, pg. 115-131.
Rupnik, M. (2009) Molecular variability in clostridium difficile large clostridial toxins. V:
Brüggemann, Holger, Gottschalk, Gerhard (eds.). Clostridia : molecular biology in the post-genomic
era. Norfolk, UK: Caister Academic Press, pg. 131-142.
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