Ministry of Health General Directorate of Health Institutes and Colleges Educational Affairs Department CURRICULUM FOR HEALTH COLLEGES Department / Specialty : PHARMACY ITEM COURSE TITLE & CODE CONTENTS PHARMACOLOGY 2 PHR 204 DURATION 3 hours weekly for 15 weeks IV LEVEL TEACHING STAFF REQUIRED OBJECTIVES PRECEDING COURSES MAIN SUBJECTS a Ph.D. holder in Pharmacology By the end of this course the student is expected to : 1. focus on the different groups of drugs affecting the central nervous system ; their mechanisms of action, indications and major side effects, giving some importance to drugs of abuse 2. learn the classification, names of drugs, dosage forms, routes of administration, mechanisms of action, uses and adverse effects of Analgesics, Antipyretics, Non-steroidal anti-inflammatory drugs, Antirheumatic drugs and drugs used in gout 3. understand the importance of autacoids in relation to the mechanisms underlying pain, allergy and other related disorders 4. gain good knowledge of drugs that act on the GIT and drugs affecting respiratory disorders 5. understand the importance of water and electrolytes balance prior to the study of the renal and cardiovascular systems Anatomy - Physiology - Biochemistry 1. Drugs affecting the CNS 2. Autacoids 3. Analgesics, Non-steroidal anti-inflammatory 1 drugs, antirheumatic drugs, drugs used in gout and drugs used in migraine 4. Drugs used in Respiratory disorders 5. Drugs used in GIT disorders 6. Water and electrolytes balance MAIN TEACHING STRATEGIES METHODS OF ASSESSMENT REFERENCES Delivery of Lectures, Holding Class Seminars, Class Discussion * 45% at least 2 theory exams during the term * 5% attendance and behaviour * 50% Final exam 1. Goodman & Gilman’s The Pharmacological basis of Therapeutics (The latest edition) 2. Basic & clinical pharmacology ,by Bertman G. Katzung (the latest edition) 3. Pharmacology , by Rang , Dale & Ritter (the latest edition) 4. Clinical Pharmacology ; Laurence & Bennett (the latest edition) 5. Pharmacology ; Jacob , L.S. (the latest edition) 2 CURRICULUM CONTENTS Course Title : UNIT Pharmacology 2 CONTENTS HOURS Drugs acting on the central nervous system 2. UNIT 3. 1 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. - Overview of the Central Nervous System and Related Disorders - Sedative-Hypnotic Drugs - The Alcohols - Antiepileptic Drugs - General Anesthetics - Local Anesthetics - Skeletal Muscle Relaxants - Management of Parkinsonism - Antipsychotic Agents and Lithium - Antidepressant Agents - Opioid Analgesics and Antagonists - CNS Stimulants - Drugs used in Migraine - Drugs of Abuse 14 Autacoids UNIT 2 * Histamine agonists * Clinical uses, toxicity, and contraindications * Histamine antagonists - H1-receptor antagonists - H2-receptor antagonists * Serotonin agonists * Clinical uses, toxicity, and contraindications * Serotonin antagonists * Melatonin * The Ergot Alkaloids - Mechanism of action - Clinical uses, toxicity, and contraindication * Prostaglandins, Thromboxanes, Leukotrienes, and Related Compounds - Mechanism of action - Tissue and organ system effects - Clinical application, toxicity, and contraindications - Inhibitors 3 9 Nonsteroidal Anti-Inflammatory Drugs; Antirheumatic Drugs; Nonopioid Analgesics; Drugs used in Gout UNIT 3 * * * * * * Mechanism of inflammation Nonsteroidal anti-inflammatory drugs (NSAIDs) Antirheumatic drugs Glucocorticoid drugs Other non-narcotic analgesics Drugs used in gout - Diseases affecting drug metabolism * Drugs used in migraine 9 Drugs used in Respiratory Tract Disorders UNIT 4 * Bronchodilators * Antihistamines - Non-sedative antihistaminics - Sedative antihistaminics * Mucolytics * Cough Preparations * Nasal Decongestants 4 Drugs Affecting the G.I.T. UNIT 5 UNIT 6 * * * * * * * * Drugs used in the treatment of peptic-ulcers Drugs promoting gastrointestinal motility Antiemetic Drugs Pancreatic enzyme replacement therapy Laxatives Antidiarrheal Drugs Drugs used for the dissolution of gallstones Drugs used in the treatment of chronic inflammatory bowel disease Body water & Electrolytes content and Acid-Base balance - Factors affecting volume and constituents of body fluid - Electrolyte balance disturbance - Acid-Base balance disturbance 4 6 3 Ministry of Health General Directorate of Health Institutes and Colleges Educational Affairs Department CURRICULUM FOR HEALTH COLLEGES Department / Specialty : PHARMACY ITEM COURSE TITLE & CODE DURATION CONTENTS Pharmaceutics 2 PHR 206 3 hours weekly (Theory) + 2 hours weekly (Practical) for 15 weeks IV LEVEL TEACHING STAFF REQUIRED OBJECTIVES an M.Sc. or a Ph.D. holder in Pharmaceutics This course is designed to focus on a variety of topics: 1. Mixtures ; their types and compounding methods 2. Parenteral preparations ; solvents used, sterilization and quality control tests required 3. Drops (eye-ear-nasal) ; sterilization procedures and preservation, filling and storage Pharmaceutics 1 PRECEDING COURCES MAIN SUBJECTS 1- Mixtures 2- Suspensions 3- Parenteral preparations 4- Eye , Ear and Nasal drops MAIN TEACHING STRATEGICS Delivery of lectures using overhead projector , Class Discussion METHODS OF ASSESMENTS 20% Two periodical theory exams during the term 10% One practical exam during semester. 5% Attendance and behaviour. 10% Oral exam. 20% Final practical exam. 35% Final theoretical exam. 1- Drug Calculations, Mulholland 5th Ed.., 1996. 2- Remington, The Science and Practice of 5 REFERENCS Pharmacy, Voliand II, 19th Ed., 1995. 3- Pharmaceutical Practice, A.J. Winfield, R.M.E. Richard; 2nd Ed. 1999. 4- Pharmaceutics, The Science of Dosage Forms Design ; M.E.Aulton, 2nd Ed., 2002. 5-Pharmaceutical Dosage Forms and Delivery Systems ; Howard Ansel ; Loyd V. Allen Nicholas Popovich ; 7th Ed., 1999. 6 CURRICULUM CONTENTS COURSE TITLE : Pharmaceutics 2 UNIT CONTENTS (Theory) HOURS Mixtures UNIT 1 * Simple mixtures (definition & chemicals used) * Addition of volatile liquids * Procedures for preparation of simple mixtures * Mixtures containing insoluble dispersible substances * Mixtures containing insoluble non-dispersible substances * Suspending agents used * Mixtures containing liquids and precipitate forming mixture * Mixtures containing slightly miscible liquids. * Mixtures containing effervescent ingredients 9 Suspensions UNIT 2 - Definition - Criteria for a good suspension - Interfacial properties of suspended particles * surface free energy * electrical properties - Flocculation and deflocculation in suspensions - Settling in suspensions 12 - Formulation of suspensions Parenteral Medications and Sterile Fluids UNIT 3 - Definition and route of administration - Solvents and vehicles for injection - Added substances - Methods of sterilization - Pyrogens and pyrogen testing - Containers and their types - Packaging, labeling and storing of injections - Quality control tests 7 16 Eye – Ear – Nasal Drops UNIT 4 - Definition Excipients used Preparation procedures Preservatives used in preparation Osmotic pressure and pH control 8 8 CURRICULUM CONTENTS COURSE TITLE : Duration : Teaching Staff Required : UNIT Pharmaceutics 2 (Practical) 2 hours weekly for 15 weeks a B.Sc. holder in Pharmacy CONTENTS HOURS Mixtures UNIT 1 - Sodium chloride mixture Ferrous sulphate mixture Magnesium carbonate mixture Calcium carbonate mixture Chalk mixture, paediatric BP Ammonium chloride mixture BP Potassium citrate mixture 10 Suspensions UNIT 2 - Preparation of magnesium carbonate suspension - Determination of sedimentation rate for different suspensions - Preparation of suspensions using suspending agents 8 Eye-Ear-Nasal Drops UNIT 3 - Hydrogen peroxide ear drops Ichthammol glycerin ear drops Sodium bicarbonate ear drops Benzocaine ear drops Alkaline nasal wash Ephedrine nasal drops. Zinc sulphate eye drops Sulphacetamide eye drops Pilocarpine eye drops 9 12 Ministry of Health General Directorate of Health Institutes and Colleges Educational Affairs Department CURRICULUM FOR HEALTH COLLEGES Department / Specialty : PHARMACY ITEM CONTENT ANALYTICAL CHEMISTRY COURSE TITLE AND CODE CHEM 210 DURATION 2 hours weekly (Theory) + 2 hours weekly (Practical) for 15 weeks LEVEL IV TEACHING STAFF REQUIRED an M.Sc. or a Ph.D. holder in Analytical or Pharmaceutical Chemistry The course includes the knowledge of analytical chemistry and its applications in the pharmaceutical fields with special concentration on qualitative and quantitative types of drug analysis. The applications include OBJECTIVES functional group analysis by titrimetric, spectroscopic and chromatographic methods. Upon completion of this course the student will be able to: 1 Understand the importance of analytical chemistry in the field of pharmacy. 2 Know the techniques of handling pharmaceutical chemicals. 3 Consider the applications of functional group analysis in qualitative and quantitative chemical and drug analysis. 4 Know the applications of instrumental analysis e.g. spectroscopy and chromatography. PRECEDING COURSES General Chemistry & Basic organic Chemistry Concepts and types of chemical analysis MAIN SUBJECTS 1. Fundamentals of chemical analysis. 2. Hydrogen ion concentration and buffer solution. 3. Acid-base titrations. 10 4. Oxidation-reduction reactions. 5. Solubility and precipitation. 6. Compleximetric titrations. Instrumental analysis 1. Spectrophotometeric analysis. 2. Chromatographic analysis. MAIN TEACHING STRATEGIES Lectures using power point or equivalent presentation strategies. 20% at least two quizzes during the semester. METHODS OF ASSESSMENT 40% At least 5 PRACTICAL tests during course. 5% Practical report writing 5% Attendance & behaviour 30% Final theoretical examination 1.Analytical chemistry, Garry D. Christian, 6th Edition, 2003. REFERENCES 2.Vogel's Quantitative Chemical Analysis (6th Edition), 2000. 11 CURRICULUM CONTENTS ANALYTICAL CHEMISTRY (Theory) UNIT UNIT 1 CONTENTS Concepts and types of chemical analysis: HOURS 2 1. Definition and applications of chemical analysis. 2. Types of chemical analysis. UNIT 2 Fundamentals of chemical analysis: 1. Electrolytes (weak and strong) 2. Atomic and molecular weights 2 3. Equivalent weight and concentrations UNIT 3 UNIT 4 Hydrogen ion concentration: 2 Calculation of pH in aqueous solutions of acids, bases and salts Buffer solutions: 2 1. Definition, buffer capacity 2. Applications of buffer in pharmaceutical preparations Acid-base titrations:: 1. Indicators UNIT 5 2. Neutralization of acids and alkalis 3 3. Principle and application of acid-base titration in quantitative analysis of some pharmaceutical agents like aspirin analysis and basic compounds like alkaloids. UNIT 6 Oxidation-reduction reactions: 1. Definition, oxidizing and reducing agents. 2. Calculation in redox reactions Application of redox reactions in determining of the strength of iodine, hydrogen peroxide and oxalic acid. 12 3 Solubility and precipitation: UNIT 7 1. Solubility and solubility products. 3 2. Practical applications (Mohr's and Volhard methods) Compleximetric titrations: 1. Complex ion and its stability. UNIT 8 2. Chelation and chelating agents. 3 3. Application of chelation in analysis and stability of pharmaceutical preparations as determination of calcium and bismuth salts with EDTA. Instrumental analysis: UNIT 9 2 1.Definition 2.Types of instrumental analysis (spectroscopy and chromatography) 3. Advantages of instrumental analysis Spectrophotometeric analysis: Definition UNIT 10 Principle of spectrophotometric method of analysis. 4 Types of spectroscopy (Colorimetry, UV, and Flourimetry). Applications of spectrophotometry in pharmaceutical analysis as streptomycin (colourimetry) and ampicillin (UV) Chromatographic analysis: Definition Principles of chromatographic methods of analysis UNIT 11 Types of chromatography (paper chromatography, column chromatograpgy, HPLC and GC). Application of chromatography in pharmaceutical analysis as carbohydrates (paper chromat.), dyes (column chromat.), volatile oils (GC), and most drugs (HPLC). 13 4 CURRICULUM CONTENTS COURSE TITLE : Duration : Staff Required : UNIT Weeks 1, and 2 Analytical Chemistry (Practical) 2 hours weekly for 15 weeks a B.Sc. holder in Pharmacy CONTENTS Introduction to analytical chemistry laboratory 1. Handling of analytical tools like glassware, balances, equipment 2. Differences between volumetric and nonvolumetric glassware 3. Laboratory safety and handling of chemicals like conc. acids, alkalis, oxidizing agents and organic solvents (flammable) 4. How to write analytical report Weeks 3 and 4 Preparation of standard solutions Weeks 5 &6 Acid-base titrations Week 7 Buffer solutions 1. Preparation and standardization of 0.1 N HCl and 0.1N H2SO4 2. Preparation and standardization of 0.1N NaOH 1. Determination of carbonate – bicarbonate mixture 2. Determination of borax – boric acid mixture in alkaline nasal lotion 1. Preparation of buffer solutions of different pH values 2. Use of pH-meter in determining the pH of unknown solution Week 8 4 4 2 2 Precipitatimetric titrations Application of Volhard method tom determine chloride concentration in normal saline solution and/or in dextrosesaline solution for injection Week 10 4 Redox titrations Preparation and standardization of 0.1 N I2, 0.1 N Na2S2O3, 0.1 N KMnO4 Week 9 HOURS 2 Complexometric titration Determination of calcium content in calcium gluconate using EDTA and Erio T as indicators 14 2 Week 11 Tutorial class 1. How to predict the chemical method for the analysis of compounds 2. Sensitivity and application of analytical chemistry Weeks 12 & 13 Weeks 14 & 15 2 Spectrophotometry 1. Determination of the max for different coloured solutions using suitable colourimeter 2. Calibration curve of KMnO4 and assay of unknown strength 4 Chromatography 1. Isolation of dyes mixture on column chromatography 2. Application of TLC and paper chromatography in the 4 separation and identification of sugars 15 Ministry of Health General Directorate of Health Institutes and Colleges Educational Affairs Department CURRICULUM FOR HEALTH COLLEGES Department / Specialty : PHARMACY ITEM CONTENT COURSE TITLE AND CODE Pharmaceutical Chemistry DURATION 2 hours weekly (Theory) + 2 hours weekly (Practical) for 15 weeks LEVEL IV TEACHING STAFF REQUIRED a Ph.D. holder in Pharmaceutical Chemistry CHEM 211 This course includes a blend of chemical and pharmacological principles necessary for understanding the : 1. Structure-activity relationships (SAR) that simplify OBJECTIVES the understanding the pharmacological activity and side effects. 2. Pharmacokinetics of drugs (ADME). 3. Relation between the molecular structure of drugs with both the pharmaceutical dosage forms and their stability. These principles are applied to all pharmacological groups PRECEDING COURSES Basic organic Chemistry, Biochemistry and Analytical Chemistry 1. Antimicrobial agents 2. Cancer chemotherapy MAIN SUBJECTS 3. Diuretics and drugs acting on the CVS 4. Drugs acting on the CNS. 5. Analgesics and anti-inflammatory drugs 6. Antihistaminics 16 7. Vitamins and hormones 8. Drugs acting on the G.I.T. 9. Biotechnology products MAIN TEACHING STRATEGIES Delivery of Lectures, Holding Class Seminars, Class Discussion, Videotape Presentation 30 % Two theoretical Tests during the semester METHODS OF ASSESSMENT 20 % Practical Tests 5 % Attendance and behaviour 25 % Final Theoretical Examination 20 % Final Practical Examination REFERENCES 1. Wilson and Gisvold’s, Textbook Organic Medicinal Pharmaceutical Chemistry, 10th edition or the latest edition. 2. David A. William, Thomas L. Lemke and William O. Foye, Foye's Principles of Medicinal Chemistry, 2001. 17 CURRICULUM CONTENTS Course Title : Pharmaceutical Chemistry (Theory) CONTENTS UNIT HOURS Antimicrobial Agents: UNIT 1 UNIT 2 1. Anti-infective agents (antiseptics, preservatives, antifungal, anti-T.B, anthelmintics, antimalarials and antiprotozoal). 2. Antibacterial antibiotics (-Lactam, aminoglycosides, chloramphenicol, tetracyclines, macroclides and polypeptides). 3. Antiviral agents Cancer chemotherapy: Alkylating agents, antimetabolites, hormones and other antineoplastic compounds. 5 2 Drugs acting on the CNS: UNIT 3 1. CNS depressants (anesthetics, sedatives- hypnotics, antipsychotics, skeletal muscle relaxants and antiepileptics. 2. CNS stimulants (analeptics, MAO inhibitors and antidepressants) 4 Analgesics and anti-inflammatory Drugs : UNIT 4 1. Morphine and related compounds 2. Anti-tussives 3. Anti-inflammatory analgesics (aspirin, arylacetic acid derivatives and phenacetin) 2 Diuretics and cardiovascular agents: UNIT 5 UNIT 6 1. Carbonic anhydrase inhibitors, high-ceiling diuretics, potassium-sparing diuretics 2. Antiangina, antiarrhythmic, and antilipidemic agents 3. Antihypertensive agents 4. Anticoagulants Antihistamines: 1. H1- Receptor antagonists 2. H2- Receptor antagonists 18 3 2 UNIT 7 Vitamins: 1. Fat soluble vitamins 2. Water soluble vitamins Hormones and Hormone Antagonists : UNIT 8 UNIT 9 UNIT 10 1. Steroidal hormones 2. Peptide hormones 3. Prostaglandins Drug acting on GIT: 1. Anti-diarrheal 2. Laxatives and emollients Biotechnology products: 1. Type of biotechnology products 2. Stability and handling of biotechnology products 19 4 5 1 2 CURRICULUM CONTENTS COURSE TITLE : Duration : Staff Required : Pharmaceutical Chemistry 2 hours weekly for 15 weeks a B.Sc. holder in Pharmacy UNIT Weeks 1, and 2 (Practical) CONTENTS HOURS Introduction to pharmaceutical chemistry laboratory 1. Types of functional groups 2. The use of functional groups in qualitative analysis of 4 pharmaceutical agents 3. Types of analytical processes (Chemical and Instrumental analysis) used in qualitative analyses 4. How to write analytical report Weeks 3 and 4 Limit tests and purity of water 1. Types of water and water hardness 2. Limit tests for chloride, sulfate and heavy metals in tape 4 and drinking water Weeks 5 Application of acid-base &6 1. Analysis of Aspirin tablets 2. Identification of aspirin (acidic), paracetamol (phenolic) 4 and isoniazide (basic) tablets 3. Determination of alkaloidal contents in Ipeca extract Weeks 7 & 8 Redox titrations 1. Determination of I2 content in betadine solution 2. Determination of H2O2 using KMnO4 3. Bromometrically determination of INH 20 4 Weeks 9, & Application of preciptatimetry 10 Identification of alkaloids (Atropine, Hyoscine, Quinine, 4 Quinidine, ..etc) by different alkoidal precipitating agents Week 11 Tutorial class How to predict the chemical method for analysis of unknown 2 pharmaceutical agents Weeks 12 & 13 Spectrophotometry 1. Colourimetric determination of adrenaline injection 2. UV determination of chloramaphenicol preparation 4 3. How to use spectroscopic methods in identification of unknown compounds (conjugation and its effect on method of analysis) Weeks 14 & 15 Chromatography 1. Application of TLC and paper chromatography in the separation and identification of sugars 2. Application of HPLC in the separation and identification of drugs (DEMO presentation) 3. Application of GC in identification of a mixture of volatile oils 21 4 Ministry of Health General Directorate of Health Institutes and Colleges Educational Affairs Department CURRICULUM FOR HEALTH COLLEGES Department / Specialty : PHARMACY ITEM COURSE TITLE & CODE CONTENT Communication Skills DURATION 1 hour weekly for 15 weeks COM 212 IV LEVEL an M.Sc. or a Ph.D. holder in a pharmaceutical science , with a good command of English TEACHING STAFF REQUIRED OBJECTIVES PRECEDING COURSES MAIN SUBJECTS MAIN TEACHING STRATEGIES METHODS OF ASSESSMENTS By the end of this course the student will be able to : 1. Communicate properly and effectively with patients 2. Understand and apply patient’s compliance methods 3. Communicate politely and in good faith with their teachers , class mates, , and with other colleagues English Language 1. Introduction to communication Skills 2. Communication Obstacles 3. Listening skills 4. Conversation and ethics of communication Delivery of Lectures , Holding Class Seminars, Class Discussion - 45% At least 2 theory exams during the term - 5% Attendance and behaviour - 50% Final examination 22 REFERENCES 1. Communication in Pharmacy Practice , Lea Febiger , William Tindal (the latest edition) 2. Communication Skills in Pharmacy Practice ; Tindall , Beardsly Kimberlin ; 3rd edition , 1994 . CURRICULUM CONTENTS Communication Skills UNIT UNIT1 CONTENTS Introduction to Communication - Elements of good communication - Principles of patients communication - Enhancement of communication with patients UNIT2 3 Communication Obstacles - Environmental obstacles - Personal obstacles - Obstacles related to the patient UNIT3 3 Listening skills - UNIT4 HOURS Listening obstacles Reflexes associated with listening Enhancement of listening Listening training and practice Patients consultations 4 Conversation and the Ethics of communication - Dealing with incoming calls to the pharmacy - Dealing with outgoing telephone calls from the Pharmacy - Ideal communication level in the pharmacy - Ethics of patients communication 23 5 Ministry of Health General Directorate of Health Institutes and Colleges Educational Affairs Department CURRICULUM FOR HEALTH COLLEGES Department / Specialty : PHARMACY UNIT CONTENTS COURSE TITLE & CODE Hospital Pharmacy PHR 213 2 hours weekly for 15 weeks DURATION IV LEVEL TEACHING STAFF REQUIRED OBJECTIVES an M.Sc or a Ph. D. holder in a pharmaceutical science , preferably in clinical pharmacy Upon completion of this course the student will be able to: 1. Consider the role of the pharmacy department in the hospital and the role of pharmacy technicians in the pharmaceutical services 2. Understand the method of medicament arrangement, storage and registration of medicines 3. State the regulations of drug dispensing and the precautions applied 4. Understand and calculate I.V prescriptions 5. Understand the role of different committees that exist in the hospital 6. learn about drug handling in in-patient and out-patient departments Biology , Pharmaceutics PRECEDING COURSES MAIN SUBJECTS 1- Introduction to hospital pharmacy 2- Pharmacy Department committees 3- Out-patient medication system 4- In-patient medication system 5- Intravenous admixture system 24 MAIN TEACHING STATEGIES 6- Intravenous nutrition 7- Pharmaceutical calculation Interactive discussion , memorizing and understanding METHODS OF ASSESSMENTS 45% At least two theory written exams during the semester 5% attendance and behaviour 50% Final theory Exam REFERENCES -Hospital Pharmacy; William E. Hassan J.R., Lea-Febiger, Latest Edition. -Pharmacy, Drugs and medical care; Mickey Smith, David Knapp, Williams and Wilkins, Latest Edition - Source book on unit dose drug distribution. ASHP., Latest Edition 25 CURRICULUM CONTENT Course Title : UNIT Hospital Pharmacy CONTENTS HOURS Introduction to Hospital Pharmacy UNIT 1 - Role of pharmacy in health services - Role of pharmacy technician in the pharmaceutical services - Pharmacy site and area. - Pharmacy equipment * Area requirement * Equipment design, size and location * Equipment construction * Equipment cleaning and maintenance - Organizational structure of the pharmacy department. 6 Pharmacy Department committees UNIT 2 - Infection control committee * Responsibilities and function of infection control committee * Role of pharmacist in infection control committee - Antibiotics committee * Responsibilities and function of antibiotics committee * Role of pharmacist in antibiotics committee - Pharmacy and therapeutic committee * Responsibilities and function of PTC committee * Role of pharmacist in PTC committee * Organization and operation of PTC committee - Quality assurance committee. * Responsibilities and function of QAC committee * Role of pharmacist in QAC committee 4 Out-patient medication system UNIT 3 - Reasons for the need of out patient department and type of patients receiving medications from out patient pharmacy - Location of out patient pharmacy - Out patient activity chart and drug prescription 26 5 system including prescription writing and dispensing procedure - Dispensing of narcotics and controlled drugs * classification of controlled drugs * controlled drug register * prescription for controlled drugs In-patient medication system - Individual prescription medication for each patient UNIT 4 - A complete floor stock system Unit dose system Prescription for in - patient pharmacy Emergency drugs List 3 Intravenous Drug admixture system * Component of an I.V admixture programme UNIT 5 - Preparation area Stability Incompatibility Aseptic techniques Patient I.V profiling Labeling and check systems Auxiliary label Quality assurance and control Refrigeration 5 Intravenous nutrition UNIT 6 - Overview of I.V. nutrition elements including minerals, vitamins, protein and energy requirements - Examples of patent solutions available for I.V. - Overview of the site of administration ; advantages and disadvantages 5 Pharmaceutical calculations UNIT 7 - Additives (admixtures) - Hyperelimentation solution - Rate of flow of I.V. fluids 27 2 Ministry of Health General Directorate of Health Institutes and Colleges Educational Affairs Department CURRICULUM FOR HEALTH COLLEGES Department / Specialty : UNIT Course title& Code Duration PHARMACY CONTENTS Pharmacy Ethics and Laws PHR 214 2 hours weekly for 15 weeks IV Level Teaching Staff Required Objectives a B.Sc. holder in Pharmacy By the end of this term the student is expected to learn : 1- the history of pharmacy practice 2- the low and regulations of pharmacy practice 3- drug information sources None Preceding Courses Main Subjects Ethics, legislation, laws and regulations of the pharmacy practice profession Main Teaching - To allow students become acquainted with the knowledge of laws and regulations of pharmacy practice in an easy way by using Strategies overhead or multimedia projector - Teacher – students interactive methods Methods of Assessments 1-Attendance and behavior (5%) 2-two theoretical midterm exams (45%) 3-final theory exam (50%) References 1-Drug information,, latest ed. 2-Laws of pharmacy practice in Saudi Arabia, latest ed. 3-Dules and guidelines of narcotics, latest ed. 28 CURRICULUM CONTENTS course title: UNIT UNIT 1 UNIT 2 UNIT 3 Ethics and Laws of Pharmacy CONTENTS HOUIRS - Introduction and historical data - Rules of pharmacy establishment including public and private pharmacies and drug stores 4 - Rules for establishing of medication factories - Equipment and instruments available in factories - Guidelines for products labeling 6 - Rules for registration of drug companies - Rules for pharmaceutical products registration 4 UNIT 4 - Scientific offices - Rules for scientific offices opening. - Definition of controlled medication and narcotics UNIT 5 - Handling of controlled medication - Importation and dispensing of narcotics. - Recording of controlled medications - Annual report of narcotics UNIT 6 - Scientific references and updating information utensils, (pharmacopeias, abstracts and index system, microfilm system and computerized programmes) 4 UNIT 7 - Punishment committee - Unlawful pharmacy practice - Lawful punishment. 4 29 4 4