INBAR FRIEDRICH BEN-NUN, PH.D. ____ 3844 Camino Lindo San Diego, CA 92122 (C) 858- 405-3367 golan.inbar.bn@gmail.com __ SUMMARY OF QUALIFICATIONS Stem Cell Scientist 3+ years of research team management 5+ years of postdoctoral experience in stem cell research. Expertise in culturing human embryonic stem cells (hESCs) and generating induced pluripotent stem cells (iPSCs) from various species (human, non-human primates, mouse and rhinoceros). 10+ years of molecular biology and biochemistry experience. TECHNICAL EXPERTISE Experience in diverse methods and applications in human pluripotent stem cell biology, molecular biology and biochemistry including: Culturing and differentiating embryonic stem cells Transient and stable transfections qRT-PCR Western blots iPSC generation from human, non-human primates and rhino Retroviral, lentiviral, adenoviral production and infection Flow cytometry Cryopreservation culturing mammalian cells Immunostaining RNAi Kinase assays EXPERIENCE Research positions Research associate The laboratory of Prof. J. Loring, Center for Regenerative Medicine, The Scripps Research Institute, La Jolla, CA 2007 - present Studied the effect of microRNA on cellular reprogramming. Generated hiPSCs from human, mouse and endangered species (Northern white rhinoceros and non-human primates drill and chimpanzee). Postdoctoral fellow The laboratory of Prof. N. Benvenisty, The Hebrew University of Jerusalem, Jerusalem, Israel Studied the effect of microRNA on p21 levels in hESCs. 2005 - 2007 Teaching positions Mentor Mentoring undergraduate students. CIRM (California Institute for Regenerative Medicine) Bridges to Stem Cell program. Instructor Giving tutorials and assisting with student’s laboratory work. NIH Human Embryonic Stem Cell Comprehensive Training Course, The Scripps Research Institute, La Jolla, CA Teaching Assistant Laboratory supervisor and instructor, Advanced Biochemistry for B.Sc. students, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel. Peer review Served as a reviewer for Stem Cells and Development 2009 - present 2008 1997 - 2004 EDUCATION Ph.D. Cancer Research The Hebrew University of Jerusalem, Jerusalem, Israel. PhD Thesis: Harnessing PKR activation for the selective killing of lymphoma cells. Mentors: Prof. A. Levitzki, Department of Biological Chemistry, The Hebrew University of Jerusalem, and Prof. H. Ben-Bassat, Laboratory of Experimental Surgery, Hadassah University Hospital, Jerusalem, Israel. 1999 - 2005 M.Sc. Molecular and Structural Biology Graduated with distinction The Hebrew University of Jerusalem, Jerusalem, Israel. MSc Thesis: Arachidonic acid metabolism – a putative target for AG-555 Mentors: Prof. A. Levitzki, Department of Biological Chemistry, The Hebrew University of Jerusalem, and Prof. H. Ben-Bassat, Laboratory of Experimental Surgery, Hadassah University Hospital, Jerusalem, Israel. 1997 - 1999 Teaching Diploma, Biology The Hebrew University of Jerusalem, Jerusalem, Israel. 1995 - 1997 B.Sc. Biology Graduated with distinction The Hebrew University of Jerusalem, Jerusalem, Israel. 1994 - 1997 PUBLICATIONS 1. Inbar Friedrich Ben-Nun, Susanne C. Montague, Marlys L. Houck, Yu-Chieh Wang, Suellen J. Charter, Louise C. Laurent, Oliver A. Ryder and Jeanne F. Loring. Generation of induced pluripotent stem cells for conservation of endangered species. Submitted for publication. 2. 3. 4. 5. 6. Inbar Friedrich Ben-Nun and Benvenisty, N. Human embryonic stem cells as a cellular model for human disorders. Molecular and Cellular Endocrinology, 252:154-159, 2006. Inbar Friedrich, Eizenbach, M., Sajman, J., Ben-Bassat, H., and Levitzki, A. A cellular screening assay to test the ability of PKR to induce cell death in mammalian cells. Molecular Therapy, 12:969-975, 2005. Inbar Friedrich, Ben-Bassat, H., and Levitzki, A. Activation of dsRNA dependent protein kinase PKR in Karpas299 does not lead to cell death. Cancer Biology and Therapy, 4: e10-e15, 2005. Inbar Friedrich, Shir, A., and Levitzki, A. RNA molecules as anti-cancer agents. Seminars in Cancer Biology. 14: 223-230, 2004. Shir, A., Inbar Friedrich, and Levitzki, A. Tumor specific activation of PKR as a non-toxic modality of cancer treatment. Seminars in Cancer Biology, 13: 309-314, 2003. INVITED/SELECTED LECTURES 1. 2. 3. 4. 5. 6. 7. 8. Cellular reprogramming of endangered species. California Institute for Regenerative Medicine (CIRM) Stem Cells training course. The Scripps Research Institute, La Jolla, CA, July 2011. Invited lecture. Generation of induced pluripotent stem cells for conservation of endangered species. Cal State University, San Marcos, CA. May 2011. Invited lecture. Cellular reprogramming of endangered species for research and conservation. STEMGENT Human Cellular Reprogramming Training Course, San Diego, CA. December 2011, February 2011. Invited lecture. Cellular reprogramming of the critically endangered species northern white rhinoceros. Stem Cell Interest Group, The Salk Institute, La Jolla, CA. February 2011. Invited lecture. Cellular reprogramming of the drill endangered species. STEMGENT Mouse Cellular Reprogramming Training Course, San Diego, CA. November 2010. Invited lecture. Cellular reprogramming of endangered species. California Institute for Regenerative Medicine (CIRM) Stem Cells training course. The Scripps Research Institute, La Jolla, CA, November 2010. Invited lecture. Cellular reprogramming of endangered species. California Institute for Regenerative Medicine (CIRM) Bridges to Stem Cells training course. The Scripps Research Institute, La Jolla, CA, July 2010; August 2010. Invited lecture. Selective killing of cancer cells by specific activation of the double-stranded RNA dependent protein kinase-PKR. 11th Conference of the International Society for Cancer Gene Therapy (ISCGT), London, England, 2002. Selected lecture. AWARDS/FELLOWSHIPS Postdoctoral fellowship, The O’Keeffe Foundation. Postdoctoral fellowship, Millipore. Unrestricted. CIRM (California Institute for Regenerative Medicine) Trainee Grant. The Lady Davis postdoctoral fellowship. The Hebrew University of Jerusalem. Hebrew University Rector's Fellowship for outstanding students. Travel Grant. The Authority for Research Students, The Hebrew University of Jerusalem. Onyx Poster Prize, the 11th conference of the ISCGT (International society for cancer gene therapy). Noah Lichtenstein Prize. The Hebrew University of Jerusalem. Golda Meir Doctoral Fellowship. The Hebrew University of Jerusalem. ASM (American Society for Microbiology) Travel Grant. Honors Scholarship. The Hebrew University of Jerusalem, Israel. Dean's List. The Hebrew University of Jerusalem, Israel. 01/2010 - present 04/2009 - 12/2009 04/2008 - 03/2009 10/2005 - 09/2006 10/2001- 09/2004 2003 2002 2002 2002 2001 1996 1995