Cancer survival in the UK and Europe, 1995-2009 Cancer survival rates in the UK are trailing 10 years behind the rest of Europe Cancer survival ratesi in the UK are currently at a level or lagging behind what many other European countries had already achieved by the late 1990s, according to new analysis by Macmillan Cancer Support. Using data from the CONCORD-2 study, which compared five-year net survival rates for a range of common cancers across the globe, we show that survival rates in the UK for lung, breast, colon and stomach cancer are currently trailing 10 years behind several other European countries. For example, the UK is at least 10 years behind Sweden for three of the four most Country commonly diagnosed cancers (colon, breast and lung). The UK and Sweden have similar levels of wealth, both countries have universal access to healthcare, and both collect high-quality cancer data from 100% of the populationii. The table below shows a selection of cancer types where the UK is at least 10 years behind other countries. While the UK has seen an increase in cancer survival between 1995-1999 and 2005-2009, these other countries have also continued to improve, meaning that the UK has failed to close the gap. Five-year net survival Five-year net survival % increase from rate rate 1995-1999 to (1995-1999) (2005-2009) 2005-2009 Breast cancer Most common cancer diagnosis in the UKiii UK 74% 81% 9% Sweden 84% 86% 3% Franceii 84% 87% 4% Italyii 83% 86% 4% March 2015 Country Five-year net survival Five-year net survival % increase from rate rate 1995-1999 to (1995-1999) (2005-2009) 2005-2009 Lung cancer 2nd most common cancer diagnosis in the UKi UK 7% 10% 32% Austria 14% 18% 27% Finland 11% 12% 12% Germanyiv 12% 16% 40% Italyii 13% 15% 14% Netherlands 12% 15% 19% Norway 11% 15% 40% Colon cancer 4th most common cancer diagnosis in the UKi UK 48% 54% 12% Finland 59% 63% 7% Franceii 57% 60% 5% Italyii 58% 63% 10% Netherlands 55% 60% 8% Norway 56% 62% 11% Sweden 55% 63% 13% March 2015 Country Five-year net survival Five-year net survival % increase from rate rate 1995-1999 to (1995-1999) (2005-2009) 2005-2009 Stomach cancer 15th most common cancer diagnosis in the UKi UK 15% 19% 28% Austria 30% 33% 12% Germanyii 23% 32% 39% Italyii 31% 32% 4% Norway 21% 24% 14% Sweden 21% 23 % 9% About the research These figures are based on an analysis of the most recent results from a global study of cancer survival, the CONCORD-2 study, published in the leading medical journal The Lancetv in 2014. The study uses data on cancer diagnoses from 279 population-based cancer registries in 67 countries for 25.7 million adults (age 15–99 years) and 75,000 children (age 0–14 years) diagnosed with cancer during 1995–2009 and followed up to December 31, 2009, or later. We investigated all adult cancers and European countries included in CONCORD-2 to find cases where the upper confidence interval (CI) for the UK survival rate in 200509 is smaller than the lower CI for the comparison country in 1995-99. These are March 2015 cases where we can be most certain than the UK survival for 2005-09 was below the other country’s survival for 1995-99. Therefore there may be other examples where the UK is lagging 10 years behind other countries. In this document we have highlighted clear examples of countries and cancers where we lag behind rather than listing all cases. i Five-year age-standardised net survival (%) in adults (1599 years). This is adjusted for background mortality in every country or region by age (single year), sex, and calendar year, and by race or ethnic origin in some countries. Net survival can be interpreted as the proportion of cancer patients who survive up to that time, after eliminating other causes of death (background mortality). The quality and completeness of cancer registration data can affect both incidence and survival estimates and, thus, the reliability of international comparisons. However the CONCORD researchers developed a suite of quality control programs to systematically check and revise their data. ii Both Sweden and the UK take part in the International Cancer Benchmarking Partnership based on having comparable wealth, universal access to health care, and longstanding, high-quality, population-based cancer registration (Coleman M et al. The IMWG (2011) Cancer survival in Australia, Canada, Denmark, Norway, Sweden, and the UK, 1995–2007 (the International Cancer Benchmarking Partnership): an analysis of populationbased cancer registry data. Lancet 377: 127–138 http://www.thelancet.com/journals/lancet/article/PIIS014 0-6736%2810%2962231-3/fulltext) iii England - Office of National Statistics. Cancer Registration Statistics, England, 2012. Available from: www.ons.gov.uk/ons/publications/re-reference-tables. html?edition=tcm%3A77-352128. Wales - Welsh Cancer Intelligence and Surveillance Unit. Official Statistics Trends. Available from: www.wcisu.wales.nhs.uk/officicalstatistics-exel-files-of-trend. N. Ireland - Northern Ireland Cancer Registry. Online Statistics. Available from: www.qub.ac.uk/researchcentres/nicr/CancerData/OnlineStatistics/ Scotland - ISD Scotland. Cancer Incidence in Scotland 2012. Available from: www.isdscotland.org/HealthTopics/Cancer/Publications/datatables.asp?id=1233#1233. iv Data does not cover 100% of population (France – 18%, Germany – 44%, Italy – 39%) v Allemani C, Weir HK, Carreira H et al and the CONCORD Working Group. Global surveillance of cancer survival 1995–2009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2). Lancet 2015; 385: 977–1010. http://dx.doi.org/10.1016/S0140-6736(14)62038-9 March 2015