Format for a NETWORK programme application – Concept note South (Identification phase) Call Network University Cooperation (NETWORK) 2015 1. Description of the project context Enhancing Infectious Diseases Education and Research In Ethiopia Infectious diseases such as malaria, tuberculosis and HIV/AIDs contribute to the large proportion of morbidity, mortality and disability in Ethiopia. This needs an urgent call for increased and sustained efforts to train the humanpower required to confront this development menace and to promote research towards the development of new or improved approaches for vaccines, drugs and diagniostics. This seeks establishment of a network University collaboration (NUC) between Jimma University and and other partner institutions (Hawassa University, Ambo University and Addis Ababa College of Veterinary Medicine and Agriculture). Jimma University (JU) with long experience and strong infrastructure leads the network while Hawassa University (HU), Ambo University (AU) and Addis Ababa University College of Veterinary Medicne and Agriculture (CVMA) will be partner universities. JU will support to build the capacity of the partner institutions through joint Masters and PhD training and conducting collaborative research focusing on the causes, epidemiology, pathogenesis and control of malaria, tuberculosis and HIV/AIDs. JU will serve as the hub in the network to share scientific expertise and resources to partner institutions. The scope of the capacity building provided by JU will also be expanded to include short and medium term training programs. The NUC initiative achieves excellence through the following objectives: (i) Train high level health professionals and academics on infectious diseases and research through MSc and PhD programs; (ii) Conduct collabortaive research to develop new disease control tools and increase research out puts.(iii) Serve as a core facility with state-of-the art laboratories to support infectious diseases research to enhance collaborative research among researchers/scientists in partner institutions 1.1. Background of the project Original idea and steps undertaken to elaborate the idea. Infectious diseases such as malaria, tuberculosis, soil transmited helimenthiasis and zoonotic diseases have been the main research topics in the IUC programme at Jimma University, resulting in the building of local capacity in terms of human power by producing over seven individuals with PhD and seven others are close to finalize their PhD study. Jimma University established substantial research infrastructure (Molecular Biology Laboratory, Parasitology and Immunology Laboratory, Mycobacteriology laboratory, Bioassay Laboratory, NTDs laboratory, Insectary, Animal House, etc.,) and eventually launched a joint doctoral school in Tropical and Infectious Diseases in collaboration with University of Ghent. Jimma University is looking for opportunities to share experience and infrastructure with other Universities in Ethiopia that operate in the context of VLIR-UOS supported projects. Jimma University has already good track record in research and capacity building. Thus, it needs to avail the infrastructure and capacity it has built over the last 10 years to do collaborative research on the proposed areas with other partner institutions. Since Jimma University built capacity and has put in place good infrastructure it will serve as a hub to bring Ambo University, Hawassa University and CVMA/AAUwhich already began research in few areas of human and animal health through Own Initiative/TEAM projects programme. This partner institutions are strategically located in areas where infectious diseases are highly prevalent and the burden from such diseases is also high. Moreover, these institutions lack human power to ensure the quality of education and research capacity for knowledge creation and technology transfer. Hence, by working with Jimma University and Flemish Universities through this network initiative they can have more and better qualified academic staff which can play a pivotal role in training high level professionals with better scientific and technical NETWORK Programme Call 2015 Annex 1: Format for the concept note South 1/6 expertise urgently needed in Ethiopia. There have been contacts between Jimma University and the different partners Universities. Jimma University and those partner Universities had successful research projects in the area of animal and human health running for several years. Capacity building and research at Jimma University have been supported by the IUC programme for the last 10 years, but additional funding is required to bring the partners universities together to develop curricula, launch joint MSc and PhD programs, conduct research and set up new research facilities at the partner Universities which do not have an IUC programme before. Therefore, additional funding is required to scale up the achievements and successes of IUC to a national scale and to other institutions. There is no other partner or government funding that can pick up the network collaboration initiative as most of other funding sources focus on institutional development. History of the collaboration / antecedents Antecedents – please indicate whether this project proposal is a continuation of an existing project, actions already undertaken, or a project in finalisation phase. Describe that project in 10 lines. Jimma university has been working with VLIR-OUS in capacity building and research since 2007 on infectious diseases, zoonotic and animal diseases, environmental health and ecology. These projects have created over 50 PhD study opportunities, established research centers and strengthend laboratory facilities to support the country's effort to improve the quality of teaching and enhance research. This collaborative project however is now at its final phase. Currently, Jimma University has a good capacity building outcome and good research track record . Moreover it has put in place good infrastructure. Therefore, in collaboration with Flemish universities, Jimma University is looking for opportunities to share experience and infrastructure with other partner universities in Ethiopia that operate in the context of VLIR-UOS to improve their capacity in conducting research. 1.2. Presentation of the project partners Local project partners Local project team (Involved staff next to the project lead and involved focal points and academics at other involved universities. Professors, assistants, (administrative) collaborators, etc, ; involved departments/universities.) The infectious diseases research team at Jimma University has a long experience on infectious diseases research. It is a multidisciplinary team comprised of medical entomologists, parasitologists, Microbiologists, epidemiologists, molecular biologists,veterinarians, public health specialists, molecular biologists, sociologists and a biostatistician. The team is thus with multidisciplinary expertise.to undertake innovative research on infectious diseases. There are also administrative and field station staffs in the team. Capacities and strategic interest (as they relate to the project) Given the scientific expertise and good infrastructure with well established & fully equipped research facilities, the infectious diseses research team at Jimma University has the capacity to lead the network to undertake high quality collaborative research with partner universities and build the capacity of partner universities through training high level health professionals and academics through joint masters and PhD programs Our strategic interest is to forge strong partnership with Souh universities and Flemish Universities to build the capacities of partner Universities in the South to train high level professionals who undertake basic and applied research to develop disease surveillance and monitoring systems and also develop new or improved technologies or tools for detection, diagnosis, trearment, prevention and control of infectious diseases. support the partner universities to develop graduate program curricula to enhance competencies in teaching and research. NETWORK Programme Call 2015 Annex 1: Format for the concept note South 2/6 Experience (academic, international) of the promoter Dr. Delenasaw Yewhalaw is a Medical Entomologist. He is an Associate Professor and currently Head of Tropical and Infectious Diseases Research Center (TIDRC) and Coordinator of Tropical and Infectious Diseases postgraduate program at Jimma University. He is a recognized malaria researcher and has enormous research experience on malaria and its vectors. He has worked on malaria research for over 11 years. He is consulting USAID/PMI on malaria vector monitoring and surveillance in Ethiopia. He has a good research track record and acquisition and management of several international research grant projects (eg., WHO/TDR, NIH, NSS, FV). He has also an experience in mentoring MSc and PhD students. Currently, he is supervising 5 MSC and 9 PhD students working on malaria, leishmaniasis, onchcercisais and other infectious diseases. He authored and co-authored over 27 papers inpeer-reviewed journals and contributed two book chapters on malaria. He has also presented his work on several international scientific conferences and symposia. Links to other relevant national and international collaborating institutes (name, nature) and society in a broader sense (government, NGO, The infectious diseases research team at Jimma University has several national, regional and international collaborating academic and research institutes, government sector agencies, societies working on malaria,TB/HIV, soil transmitted helimenthiasis, zoonotic diseases and other etc.) infectious diseases such as the International Center of Insect Physiology and Ecology, Imperial College, London, University of Crete, Greece, University of California, Irvine, Liverpool School of Tropical Medicine,University College London-UCL (UK), University of Bergen, Norway, University of Copenhagen (Denmark), London School of Hygiene and Tropical Medicine, London, UK, and Institute of Tropical Medicine, University of Crete. Local collaborating institutes include: Armour Hanson Research Institute, Ethiopian Ministry of Health, Ethiopian Public Health Institute, Ethiopian Water Resources Institute and Aklilu Lemma Institute of Pathobiology. Malaria Consortium and Ethiopian Society of Tropical and Infectious Diseases, Other involved actors (if applicable) Name and function of the actor (Partner University 1) Dr Eskinder Loha (Epidemiologist) Major (project related) activities He is a researcher on malaria, HIV/AIDS and Tuberculosis. He provides training on appropriate epidemiological tools, statistical data management skills using statistical software packages (SPSS, STATA, ENA for SMART etc). He has worked in malaria research for the last 5 years. He published over 22 scientific papers on peer-reviewed journals. He is also consulting ESHE-USAID, Save the Children- USA, Federal Ministry of Health of Ethiopia, UNICEF, World Health Organization, Integrated Family Health Program, EVIDENCE TO ACTION PROJECT on health. Capacities and strategic interest (as they relate to the project) The team constitutes a primary epidemiologists and health care expert. Hawassa University is located in a region where malaria infectious diseases such as malaria is endemic at nearby places Hence, it’s a strategic interest to start up partnership in capacity building and research with HU. Reasons for which the actor is involved in the project Partners of the network and coordinator NETWORK Programme Call 2015 Annex 1: Format for the concept note South 3/6 1.3. Link with the VLIR-UOS country strategy VLIR-UOS country stragey for Ethiopia has identified health as a national area of priority sector for intervention within the IUC programme. Therefore, building the capacity of the partner universities is a major objective. This NUC project aims to support partner universities on capacity building and research on infectious diseases of nation importance, thus scaling up capacity building to the national level through partnership. 1.4. Link with other initiatives (complementarity/synergy) Link with initiatives taken in the same domain by other organisations (local, regional, Belgian, etc.) and in other VLIR-UOS activities. The infectious diseases research at Jimma University, Hawassa University, Ambo University and CVMA/AAU are supported by many donors other than VLIR-OUS, e.g., WHO/TDR, USAID, NORHED, OHCEA, SENUPH, GLOBVAC, NIH and other projects This network will open up such new opportunities also for the partner Universities. 1.5. Beneficiaries / target group Description of the direct beneficiaries (specific objective) and indirect beneficiaries and stakeholders (external groups that are affected by the implementation of the project), their interest, attitude and possible role. The direct beneficiaries from this network project are partner universities which can build their capacity and also the lead university and partner universities which jointly reinforce their research capacity through collaborative research, technology transfer and exchange of information through networking. Moreover, disease control program of the country, the community living under the threat of infectious diseases, non-governmental organizations and policy makers indirectly benefit from the out comes of the network project. 1.6. Problem analysis General and national presentation of the sector / development problem treated in the project, as well as the political lines (development problem related to the sector analysis) In Ethiopia, infectious diseases are major public health problems. Many of these diseases (e.g., malaria, Tuberculosis,HiV/AIDS, soil transmitted helimenthiasis,schistosomisis, leishmaniasis, onchocerciasis, lymphatic filariasis, human African trypanosomiasis, etc.,) are endemic in Ethiopia and are the major causes of morbidity and mortality in the country and places a major burden in the population. High morbidity and mortality associated from infectious diseases reflect the poor state of knowledge about their causes and epidemiology and the lack of effective technologies for their control. Local specific research is important to provide accurate situation analysis on the prevalence, distribution and determinants of infection as effective control of infectious diseases is based on sound knowledge of local epidemiology of the diseases as well as understanding of the role of social and behavioral factors that informs a decision-making process for disease control. Jimma University has a long experience in infectious diseases research and partner institutions that have started to build up capacity (Hawassa University, Ambo University, CVMA/AAU) are interested to build thier capacity. Analysis of the capacity constraints the partners are confronted with (academic problem) NETWORK Programme Call 2015 Annex 1: Format for the concept note South 4/6 Jimma University have a long experience in infectious diseases research of priority and some NTDs (Malaria, TB/HIV and soil transmitted helminthiasis) while other partner institutions (HU, AU and CVMA/AAU) have started to build up capacity or are merely interested in such capacity. Jimma University has benefited from a long term IUC project and has substantial research capacity and infrastructure, and wants to use its experience to support partner universities in developing these research capacities. 2. Description of the project Summary Infectious diseseases such as malaria, tuberculosis and HIV/AIDS are pressing health and development problems in Ethiopia and in Africa as well. Infectious diseases are changing rapidly in conjunction with dramatic societal and environmental changes. There are also Important resurging, emerging and resurging infectious diseases due to climate change, resistance of pathogens to drugs and vectors to insecticides. Thus infectious diseases remain the leading cause of death and disability-adjusted life years (DALYs). To effectively address the threat of infectious diseases and reduce burden, there is a need to develop the capacity of partner institutions working on the area of such diseases and undertake collaborative research to generate data for policy decision for the containment of infectious diseases that affect, or threaten to affect, the public’s health. The expected results of this project are: 1) Build capacity of partner institutions through launching graduate programs to produce more and better qualified health professionals with better scientific and technical expertise through capacity building 2) to strengthen the infrastructure in partner institutions and enhance collaborative research among partner institutions For research activities, please elaborate the proposed research methodology and process. Not mandatory Describe the developmental relevance of the project. Infectious diseases are threats to global health resulting in considerable causes of morbidity, mortality and disability. It accounts for the majority of deaths in children and adults, absence from work and school and contribute to impaired growth in children.The disease further has serious economic impact, and is considered to have a large contribution to poverty by slowing economic growth and development. The current major concerns of these diseases are the emergence and spread of drug resistant pathogens (parasites, bacteria, and virus) and insecticide resistant vectors. High morbidity and mortality associated with these diseases reflect the poor state of knowledge about their causes and epidemiology and the limited effective technologies for their control. Furthermore, capacity for high level professional training and advanced research undertakings on infectious diseases in the local context is challenging. Effective and sustainable control of infectious diseases needs highly trained human capital and research to better understand their biological underpinnings and develop new tools including vaccines, improved diagnostics and new drugs that are critically needed to combat these major public health problems in the region. Therefore, building the capacity of partner institutions by launching joint MSc/ PhD programs to produce high level professionals and who will be involved in basic and applied research to identify, develop, validate and evaluate new tools and strategies in the diagnosis, treatment, prevention and control of infectious diseases is a key step forward. Thus, establishing such a network is a major objective of this project. 3. Needs assessment and sustainability Describe in detail the capacity of the different local units, preconditions and major problems that could be enNETWORK Programme Call 2015 Annex 1: Format for the concept note South 5/6 countered as also potential external influencing factors (feasibility). From preliminary discussion and partners mapping excercie, the human resource profile of the partner institutions is low. It was also understood that all partner institutions feel that they can learn from each other and there is readiness of the lead and experienced institution to share experience with partners and provide them access to infrastructure, and readiness of partner institutions to learn from other partner universities and share their own experience and resources with other network members. There is enthusiasm to learn, receive guidance and support from more experienced and lead partner. Partners must avail themselves to attend the consultative meetings, workshops, curriculum development and competitive grant proposal writing, so that a network can be established and run efficiently. All partners have basic capacity to set up the basic facilities at their home institution, but Jimma University has more advanced capacity because of the state-of-the art facilities it has been investing in over the last many years to run high level research, Jimma University also agrees to avail the all the facilities available in Tropical and Infectious Disease Research Center (TIDRC) and field research station for the required collaborative research with partner institutions. Priority will also be given to strengthen partnerships between partner institutions to ensure sustainability. Describe the opportunities and challenges for the sustainability of benefits (capacity retention, continuation of research activities, etc.) This research network combines South Universities with substantial and limited research experience in infectious diseases in general and in malaria, tuberculosis and soil transmitted helimenthiasis in general. This network provides opportunities for the partner institutions to.create synergy promote operational efficiency of the project. In institutions with substantial expertise such as Jimma University, it allows postdoctoral researchers to continue their research and reap the benefits of their previous PhD study. In the younger institutions, the new MSc/ PhD researchers will join efforts with their more experienced colleagues and make part of a network that will give them ample opportunities for further collaboration in the future. To maintain sustainability, the researchers from both institutions will actively be engaged in sharing of experience and expertise including writing of joint grant proposals, engagement in consultancy services, exchange of staff and students, These activities will create long-term capacity of the collaborating institutes to mobilize supplementary resources from other sources. The partnership lays foundation for further collaboration and creation of sustainable capacity. Staff turnover could be a challenge at partner institutions and a retation mechanism will be in place to engage the staff in research. NETWORK Programme Call 2015 Annex 1: Format for the concept note South 6/6