Multiple responses: The desirability approach The desirability approach is a popular method that assigns a "score" to a set of responses and chooses factor settings that maximize that score The desirability function approach is one of the most widely used methods in industry for the optimization of multiple response processes. It is based on the idea that the "quality" of a product or process that has multiple quality characteristics, with one of them outside of some "desired" limits, is completely unacceptable. The method finds operating conditions x that provide the "most desirable" response values. Desirabilit y functions of Derringer and Suich Depending on whether a particular response Yi is to be maximized, minimized, or assigned a target value, different desirability functions di(Yi) can be used. A useful class of desirability functions was proposed by Derringer and Suich (1980). Let Li, Ui and Ti be the lower, upper, and target values, respectively, that are desired for response Yi, with Li Ti Ui. Desirabilit y function for "target is best" If a response is of the "target is best" kind, then its individual desirability function is For each response Yi(x), a desirability function di(Yi) assigns numbers between 0 and 1 to the possible values of Yi, with di(Yi) = 0 representing a completely undesirable value of Yi and di(Yi) = 1 representing a completely desirable or ideal response value. The individual desirabilities are then combined using the geometric mean, which gives the overall desirability D: with k denoting the number of responses. Notice that if any response Yi is completely undesirable (di(Yi) = 0), then the overall desirability is zero. In practice, fitted response values i are used in place of the Yi. with the exponents s and t determining how important it is to hit the target value. For s = t = 1, the desirability function increases linearly towards Ti; for s < 1, t < 1, the function is convex, and for s > 1, t > 1, the function is concave (see the example below for an illustration). Desirabilit If a response is to be maximized instead, the individual desirability is y function for maximizing a response defined as with Ti in this case interpreted as a large enough value for the response. Desirabilit y function for minimizing a response Finally, if we want to minimize a response, we could use with Ti denoting a small enough value for the response. Desirabilit y approach steps The desirability approach consists of the following steps: 1. Conduct experiments and fit response models for all k responses; 2. Define individual desirability functions for each response; 3. Maximize the overall desirability D with respect to the controllable factors. Example: An example using the desirability approach Factor and response variables Derringer and Suich (1980) present the following multiple response experiment arising in the development of a tire tread compound. The controllable factors are: x1, hydrated silica level, x2, silane coupling agent level, and x3, sulfur level. The four responses to be optimized and their desired ranges are: Source Desired range PICO Abrasion index, Y1 120 < Y1 200% modulus, Y2 1000 < Y2 Elongation at break, Y3 400 < Y3 < 600 Hardness, Y4 60 < Y4 < 75 The first two responses are to be maximized, and the value s=1 was chosen for their desirability functions. The last two responses are "target is best" with T3 = 500 and T4 = 67.5. The values s=t=1 were chosen in both cases. Experiment al runs from a central composite design The following experiments were conducted using a central composite design. Run Number x1 x2 x3 Y1 Y2 Y3 Y4 Fitted response Using ordinary least squares and standard diagnostics, the fitted responses are: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 -1.00 +1.00 -1.00 +1.00 -1.00 +1.00 -1.00 +1.00 -1.63 +1.63 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 -1.00 -1.00 +1.00 +1.00 -1.00 -1.00 +1.00 +1.00 0.00 0.00 -1.63 +1.63 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 -1.00 -1.00 -1.00 -1.00 +1.00 +1.00 +1.00 +1.00 0.00 0.00 0.00 0.00 -1.63 +1.63 0.00 0.00 0.00 0.00 0.00 0.00 102 120 117 198 103 132 132 139 102 154 96 163 116 153 133 133 140 142 145 142 (R2 = 0.8369 and adjusted R2 = 0.6903); (R2 = 0.7137 and adjusted R2 = 0.4562); (R2 = 0.682 and adjusted R2 = 0.6224); 900 860 800 2294 490 1289 1270 1090 770 1690 700 1540 2184 1784 1300 1300 1145 1090 1260 1344 470 410 570 240 640 270 410 380 590 260 520 380 520 290 380 380 430 430 390 390 67.5 65.0 77.5 74.5 62.5 67.0 78.0 70.0 76.0 70.0 63.0 75.0 65.0 71.0 70.0 68.5 68.0 68.0 69.0 70.0 (R2 = 0.8667 and adjusted R2 = 0.7466). Note that no interactions were significant for response 3 and that the fit for response 2 is quite poor. Optimizati on performed by DesignExpert software Optimization of D with respect to x was carried out using the DesignExpert software. Figure 5.7 shows the individual desirability functions di( i) for each of the four responses. The functions are linear since the values of s and t were set equal to one. A dot indicates the best solution found by the Design-Expert solver. Diagram of desirability functions and optimal solutions FIGURE 5.7 Desirability Functions and Optimal Solution for Example Problem Best Solution The best solution is (x*)' = (-0.10, 0.15, -1.0) and results in: d1( 1) = 0.34 ( 1(x*) = 136.4) *) d2( 2) = 1.0 ( 2(x d3( 3) = 0.49 ( 3(x d4( 4) = 0.76 ( 4(x = 157.1) *) = 450.56) *) = 69.26) The overall desirability for this solution is 0.596. All responses are predicted to be within the desired limits. 3D plot of the overall desirability function Figure 5.8 shows a 3D plot of the overall desirability function D(x) for the (x2, x3) plane when x1 is fixed at -0.10. The function D(x) is quite "flat" in the vicinity of the optimal solution, indicating that small variations around x* are predicted to not change the overall desirability drastically. However, the importance of performing confirmatory runs at the estimated optimal operating conditions should be emphasized. This is particularly true in this example given the poor fit of the response models (e.g., 2).