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Bio-Rad Molecular Imager® Gel Doc™ XR+ System
Catalog item 1708195
Sole Source Specification
The Molecular Imager Gel Doc XR System is manufactured solely by Bio-Rad Laboratories, Inc. It is the
most automated gel documentation system that allows obtaining optimized image data and analysis
from a gel in a single uninterrupted, fast and completely repeatable workflow.
The system has the flexibility to image fluorescent and colorimetric samples.
The system is powered by Image Lab® software to enable the highest level of automation in hardware
calibration, image optimization, image capture and analysis.
Unlimited copies of Image Lab software are available with each system to allow free functionality for
sharing, analysis, and presentation of gel data.
The systems hardware components include a high-resolution 12-bit CCD camera, a light-tight
compact darkroom, slide-out transilluminator with preparative mode for added safety when
manually visualizing samples with UV excitation. The system is capable of providing trans-UV, transblue, trans-white, and epi-white light illumination. The software-driven motorized lens is controlled
via PC or Mac computer through a convenient single USB computer interface.
The Gel Doc XR+ can be used for imaging a wide variety of applications, including colorimetric and
fluorescent western blots, colony counting, nucleic acid and protein detection via colorimetric and
fluorescent stains using a large portfolio of detection methods (Ethidium Bromide, SYBR Green, SYBR
Safe, SYBR Gold, GelGreen, GelRed, Fast Blast, SYPRO Ruby, Flamingo, Oriole, CY3, Rhodamine, Green
Fluorescent Protein, Hoechst, Krypton, Silver stain, Copper stain, Zinc stain, Coomassie Brilliant Blue,
Coomassie Fluor Orange, Fluorescein, CY2, Alexa 488, Qdots 525, 565, 625 and other spectrally
similar stains, labels and dyes).
The features below and their benefits together combine to make the Gel Doc XR a unique offering to
researchers.
Feature
Capabilities powered by Image Lab software
Automated workflow from image capture to results
recorded in a protocol file
Automated Image optimization at system set up
including focus, iris and flat field calibration
Benefit
Combined automated gel imaging and analysis in a
single software application
Allows 100% repeatability of the workflow by any user
Eliminates need for training
Allows re-creating, exchanging and editing existing
workflows among multiple users
Patent pending system calibration for image size,
focus, and flat field
Produces beautiful, publication-ready images
Delivers image data that is always optimized and
reproducible without imaging artifacts for superior
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Automated image capture driven by a selected gel or
blot application
Automated image analysis
Animated tutorials for novice users
User defined data charts with instant access to Excel
functionality
Snapshot tool to copy images, lane profiles and
graphs
Raw image data export to Tiff
Software is Mac and PC compatible and license
registration is not required
High Resolution CCD USB 1.44 megapixel camera
12-bit Data Acquisition
1392x1040 (1.44MP) CCD array
4.6x4.6μm pixel size
Motorized Zoom Lens
C-mount f/1.2; 12.5-75mm zoom lens
Large Sample Platen
UV illumination area is 26 x 25cm
Universal Hood II
Light tight darkroom chamber with light baffling
Touch pad controls for iris, zoom, and focus of
the lens
USB interface
UV Transillumination
302nm UV-B
image uniformity and quantitation
Eliminates need for manual instrument adjustments
to obtain an image, saves time
Ensures that image optimization is specific to a
selected gel or blot application
Automated lane and band identification, molecular
weight or base pares evaluation, band sizing, and
quantitation based on a reference band or quantity
standards
Comprehensive 1D gel and blot image analysis in the
shortest possible time
Produces reports with data organized the way a
researcher desires
Minimized time from lab work to presentations
Engaging introduction to obtaining reliable imaging
data from gel and blot samples
Live update of results with any change of analysis
parameters
Data analysis is enriched with Excel calculations
within a single user interface
Instant copy/paste into publications and
presentations within a single user interface
Original data files can be opened in other image
analysis software without any changes to the raw
data (Quantity One, FPQuest, InfoQuest and other)
for additional study
Unlimited number of copies can be installed on
multiples computers to allow flexibility in choosing
location, media and time for data analysis
Quantitative, greater than 3.0 orders of linear
dynamic range, for all samples
high resolution imaging
For resolving closely spaced bands on a gel or blot
Allows variable spatial resolution while supporting
high collection efficiency required for faint sample
Flexibility in imaging samples of various sizes
Eliminates background from ambient light
Allows users to over-ride automated lens control at
the darkroom
Single-point connection to PC or Mac
Broad range UV illumination with a peak at 302nm.
Compatible with a wide range of applications
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254nm UV-C (optional)
365nm UV-A (optional)
Filter Slider
3-Position Filter Slider
Filters
Standard filter
520DF30nm (optional)
560DF50nm (optional)
630BP30nm (optional)
including
ethidium bromide, SYBR green, SYBR gold,
Fluorescein, Texas Red, SYPRO Ruby, GelStar, CY3,
Rhodamine, and GFP
Broad range UV illumination with a peak at 254nm.
Compatible with EtBr, SYBR green and SYBR gold
imaging.
Broad range UV illumination with a peak at 365nm.
Compatible with carbohydrate gel imaging, GFP, SYBR
green, or to visualize DNA with minimal nicking
The slider accommodates two 62mm diameter
emission filters for laboratories that wish to optimize
imaging for different stains.
Used for efficient imaging of a broad range of samples
with a single filter
Optimal filter for SYBR Green/GFP/SYBR Gold/
Fluorescein imaging
Optimal filter for CY3/Rhodamine imaging
Optimal filter for SYPRO Ruby/Oriole/Texas Red
imaging
User, system, and sample safety features
UV Safety Interlock on the main door and
transilluminator drawer
UV and White Lamp Auto Shut-off
Acrylic UV Shield
Analytical & Preparative UV Mode
Upgrade to ChemiDoc XRS+
Simple and quick change of the XR+ camera to a high
sensitivity chemiluminescence grade CCD camera
Quantity One software (optional)
Image capture
Colony counting
Protects users from UV exposure by shutting off UV
light source during opening of the main door or pull
out drawer
To preserve lamp life, system automatically shuts off
UV and white light lamps after approximately 5
minutes
Fits on and angles over the transilluminator to protect
users when manually visualizing samples on the
transilluminator
(additional protective gear such as goggles/mask and
glove are recommended)
Preparative mode reduces the light intensity of the
lamps to reduce UV exposure when manipulating a
sample (isolating bands from a gel) and to reduce UV
damage to samples
Enables high sensitivity and broad dynamic range
detection for chemiluminescent, fluorescent and
colorimetric samples
Full lens control of iris, zoom, and focus from
software acquisition window
Lens settings can be saved for reproducible imaging
Quantify colonies and distinguish blue/white colony
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Multi-channel viewer
Quick guides for Printing, Volume, Band, Colony
Counting, Differential Display, Phylogenetic Tree, and
VNTR Analyses
Band, Lane, Matching, Image, Phylogenetic,
Similarity Matrix, and VNTR Reports
Archiving of Band Detection Parameters and
Standards
17 Pre-saved Bio-Rad Standards
Mac and PC compatibility
Network versions
CFR 21-11 module
IQ/OQ procedures
selection
Allows overlay of up to 3 images assigned to
individual color channels (RGB)
Quick navigation through the acquisition and image
analysis workflow
Complete menu of reports to fit needs of different
users
Saves time and provides reproducibility for analysis of
similar samples
Convenience for faster band size determination
The Gel Doc XR+ and Quantity One are compatible
with both Mac OSX (Intel and PowerPC) and PC (Vista,
XP, and 2000) platforms
Network versions of the Quantity One software are
available as 1, 2, 3, 4, 5, and 10-user network license
configurations
Allows users to comply with CFR Part 11
requirements
Allows compliance with pharma/biotech and similar
industry regulatory requirements