LIVER DISEASE We generally treat health problem as a priority when it gives rise to substantial pain and suffering or is life threatening in the short run. Most diseases of the liver corrode a person’s body continuously but silently. Since liver diseases generally do not present as a sudden and acute condition, they have not received due attention in India where the per capita expenditure on healthcare is very limited. Consequently, there has not been much organized development in the areas of healthcare delivery or public health resource utilization for liver diseases in India. Lack of clarity in scientific understanding of liver diseases amongst professionals has also added to the problem. Policy Makers and Planners are generally more concerned about the number of deaths due to a disease, the direct) e.g. healthcare resource utilization) and indirect (e.g.. workdays lost) economic impact of the disease based on existing data. In the case of liver disease, data that are required for health-care planning are grossly inadequate in liver diseases in different regions of India. Further – perhaps, most importantly, there is inadequate understanding of the causes and processes that lead to liver diseases. These factors have resulted liver diseases being a lowpriority agenda for the country’s health planners. This scenario needs to be changed and the change can happen with our concerted efforts. THE LIVER Traditionally, the liver has often been thought of as guilty whenever the body runs into troublesome function. This has come from an age old belief that the liver holds the key to good - life and well being : Thus ,“Pitta”(bile), that comes from liver has been told to represent the state of the liver. Over years, improvements in science has provided us a much better and clear understanding of liver function and its’ disorders – but the theme remain the same. The liver by all that it does try to influence the function of other organs of the body and maintain tranquility in the body as a whole. Liver is in the first line of defense and hence through the life-course of an individual, faces many injuries – the strength and the nature of which varies. The causes include infections, different drugs, high intake of alcohol, etc. When the liver suffers an injury, it usually heals by itself, without any medication. However, if the injury exceeds a limit, or with repeated injury or because of other problems in the human body (mostly unknown), this healing process puts the surviving liver into trouble, depriving them of blood supply and nutrition. The liver slowly, but often silently, starts to lose its capacity of functioning with full efficiency. At this time, the components (called cells) of the liver become disorganized and an end-stage disease, called cirrhosis of the liver, sets in. This is an unfortunate development. Although new information reaching us tells that in early stages even cirrhosis can be improved, often these patients reach doctor so late that the only option remain is to replace the unhealthy liver by a portion of liver from a healthy person- liver transplantation. This is a difficult job - technically and an even more difficult job is to find a donor liver. Acceptability and availability of liver transplantation has got a social component that would foster awareness. Awareness on Liver The best way to reduce disease burden of a country is for her citizens to recognize diseases in themselves, be aware of the known diseases and taken preventive measures. This calls for public awareness. An important obstacle in propagating scientific awareness and education about liver diseases are the associated stigma, preconceived notions and misconceptions. Often, cleansing these notions are replacing these by scientifically enriched ideas may be as difficult a job as fighting the disease itself. Thus, the liver cirrhosis is often equated with alcohol intake and an unregulated life. As a result, many patients try to avoid seeking early medical help out of fear of getting socially ostracized. Such avoidance prevents detection of an early stage of the disease. Thus, most often, people seek medical help for liver disease only when the disease has progressed to such a stage that available treatments are not beneficial and leads to fatality. In addition, lots of magic remedies are practiced to treat persons afflicted with liver disease. There is a great social need to raise public awareness and impart education regarding liver diseases. Healthy Liver Liver health, as focus, is an inseparable part of prevailing notions and approach to public health in the society. Public health in India, despite its success has yet not attained the focus it needs. An important limitation of public health approaches in this country had been that it lacked the clarity of understanding of what to achieve and the philosophical bent of mind to convert a stubbornly mechanical issue to a social movement. This is one of the areas where Liver Foundation, West Bengal intends to contribute. Advances in molecular and cell biology as well as proteomics and glycomics have changed the face of Hepatology that we see today and envision for the next couple of years. Over the last two decades, as the language of science and knowledge have changed into one of genes, signals and clones – few disciplines have moved as fast as Hepatology into this brave new world. The stumbling block in understanding of liver diseases earlier was that, the clinical manifestations are very late and the underlying early phenomenon are too discrete and precise to be picked up by human hands, ears and the eyes – the tools that we had in the era that preceded. But now, in the late eighties and early nineties, human endeavour had focused on more precise delineation of the early phenomenon in liver diseases, with an eye to develop potentially correctible interventions based on sound principles of causation of liver disease. VALUE ADDED LINKS : 1. www.liverindia.com 2. www.livertransplantindia.com 3. www.chennailiverfoundation.org 4. www.nlfindia.com 5. www.cpaaindia.org/infocentre/clipping_lvrc.htm 6. www.liverfoundation.org 7. www.liver.ca 8. en.wikipedia.org/wiki/Liver 9. www.barcnetwork.org 10. www.childliverdisease.org 11. www.livercancer.com 12. www.liverfacts.com Contact Us & Source: Liver Foundation, West Bengal 12, Dr. M Ishaque Road (Formerly known as Kyd Street) Iran Society House Kolkata - 700 016 Phone : 91.33.2226 4675 E-mail : partha@liverfoundation.in, abhijit@liverfoundation.in Website : www.liverfoundation.in