Cell Reproduction Chromosomes—composed of chromatin that has become tightly wrapped around globules of proteins called histones. Each chromosome consists of two individual parts called chromatids. The point at which each chromatid is attached is called a centromere. In all sexually reproducing organisms, chromosomes occur in homologous pairs. Each chromosome of a pair has the same size and shape as its homologue. A cell that contains both chromosomes of a homologous pair is said to be diploid. A cell that contains only one chromosome from each homologous pair is said to be haploid. Cell reproduction—occurs when the parent cell divides producing two new daughter cells. Types of cell reproduction include: 1. Binary fission—two identical cells produced from the splitting of the original cell in two equal halves. Most cells reproduce in this manner. 2. Budding—one larger cell and one smaller cell produced from the splitting of the original cell into two cells of different sizes. A unicellular fungus called yeast reproduces in this manner. Cell cycle—includes the non-reproducing stage in which cells spend most of their life, called interphase, and the reproducing stage in which new cells are formed called mitosis. During interphase, cells are using energy to carry out the basic cell functions. New cell parts such as mitochondria and ribosomes are being produced early in interphase. About midway through interphase, each chromosome and the DNA it contains replicates. Mitosis—division of the nucleus during the reproductive portion of the cell cycle. Occurs in somatic cells throughout the body. Mitotic phases: 1. Prophase a. nucleoli disappear b. nuclear membrane disintegrates c. coiling and shortening of chromosomes give nucleus a grainy appearance d. centrioles break apart and begin to migrate toward opposite poles, spindle begins to form e. during late prophase, chromosomes appear as two joined sister chromatids joined at the centromere 2. Metaphase a. microtubules of the spindle capture the chromosomes by the centromere b. chromosomes move to the equator of the spindle and become aligned 3. Anaphase a. centromeres split and sister chromatids begin to move apart b. chromosomes migrate to opposite poles of the cell 4. Telophase a. cell cleavage furrow appears in animal cells as plasma membrane is pulled together by microtubules b. cell plate begins to appear in plants c. telophase ends with the reverse of the events that began prophase Control of the cell cycle: 1. An estimated 25 million cell divisions occur per second in the human body 2. Some cells divide at a faster rate than others, some never reproduce once they mature (nerve cells) 3. Cell-to-cell contact may be one of the mechanisms that control the rate of cell reproduction Meiosis—cell division that occurs in gonads (reproductive organs) resulting in haploid (1/2 the normal chromosome number) gametes (sex cells). Characteristics of meiosis: 1. Occurs only in gonads a. Males—testes b. Females—ovaries 2. Produces cells called gametes that have half the normal chromosome number for that species. Haploid is the term used to describe the chromosome number in this type of cell. 3. A two stage cell division. a. Meiosis one—involves the formation of tetrads and is the reduction division, that is, the division that makes the resulting daughter cells haploid. Chromosomes do not break apart at the centromeres during the first meiotic division as they do in mitosis. Crossing over may occur early in this stage of meiosis. b. Meiosis two—involves the separation of the chromatids and formation of the actual daughtercells or gametes. 4. Types of meiosis include: a. Spermatogenesis—production of the male Gametes in humans, called sperm. Four full-sized daughter cells produced per mother cell (primary spermatocyte) in this type of meiosis. b. Oogenesis—production of the female gametes in humans, ova (eggs). Produces only one full-sized daughter cell per mother cell (primary oocyte) in this type of meiosis. 5. The union of a haploid sperm and a haploid ovum produces a diploid (containing the normal number of chromosomes for a species) zygote which develops into a new individual of that species.