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Brief CURRICULUM VITAE
Dr. Dimitra Kovala-Demertzi, Professor
Date and Place of Birth : September 28th, 1944, Thessaloniki, Greece
Mail Address: Department of Chemistry, Inorganic Chemistry, University of Ioannina, 45110
Ioannina, Greece.
Email: dkovala@cc.uoi.gr
Academic Degrees
a) B.Sc. in Chemistry, 1969, Department of Chemistry, Aristotelio University of Thessaloniki
Thessaloniki,, Greece;
b) Ph.D. in Inorganic Chemistry, 1983, Department of Chemistry, University of Ioannina,
Ioannina, Greece; Title of Dissertation "Complexes of o-aminobenzylamine with Copper(II),
Cobalt(II), Nickel(II), Palladium(II) and Platinum(II)"
c) Specialization on Clinical Chemistry and Identification of professional practice. Journal of
the government N0 126/11-1980 Sect. B.
Post Doctoral Research Experience
a) July 1982 - October 1982, Donnan Laboratories, Department of Inorganic, Physical and
Industrial Chemistry, University of Liverpool, Liverpool, England, Cooperation with Senior
lecturer Dr. D. Nicholls.
b) June 1985 - September 1985, University UIA of Antwerpen, Antwerpen, Belgium,
Cooperation with Prof. E.Vanstant.
c) June 1986 - September 1986, Laboratorium Anorganische Scheikunde, Rijksuniversitair
Centrum Antwerpen, Antwerpen, Belgium, University UIA of Antwerpen, Atwerpen,
Belgium, Cooperation with Prof. H.O. Desseyn.
d) September 1991 - February 1992 , visiting Professor, Department of Chemistry, University
of Florida, U.S.A., Cooperation with Prof. R. Drago
e) August-September 1997, visiting Professor, Department of Chemistry, University of Essex,
Cooperation with Dr J.R. Miller
Professional Positions
a) Biochemical Department of Ippokrateio General Hospital of Salonica
April 1970-April 1975
Specialization on Clinical Chemistry
b) Department of Chemistry, University of Ioannina, Ioannina, Greece
June 1975 - February 1983, Assistant
February 1983 - February 1987, Lecturer
February 1987 - 1997, Assistant Professor
February 1998- 2004, Associate Professor
April 2004- now Professor
Research Activities
Inorganic, Bioinorganic and Organometallic Chemistry
Materials-Drugs- Fhysical products
Metal-Based drugs
Synthesis, characterization, structure of new complex compounds and biological
applications (Drug Dessign)
Metal complexes as drugs and as catalysts
Synthesis and Characterization of New materials (nanoparticles)
Catalysis
Study of physical products- Anti-oxidant and anticancer activity.
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Educational activity
Teaching of Introductory, Intermediate and Advanced Inorganic Chemistry to the students of
Chemistry Department, University of Ioannina. Teaching of Bioinorganic Chemistry and
metal-based drugs to post-graduated students of the Department of Chemistry of the
University of Ioannina.
Educational Greek books and chapter in international books
1. D. Kovala-Demertzi, “Laboratory experiments in Inorganic Chemistry”, Ioannina
1994, 140 pages.
2. D. Kovala-Demertzi, “Specific chapters of Inorganic Chemistry”, Ioannina 1995,
107 pages
3. D. Kovala-Demertzi “Metal-based Drugs”, in Bioinorganic Chemistry, Editor N.
Hadjiliadis, Ioannina 1999.
4. Z. Szafran, R.M. Pike, M.M. Singh “Microscale Inorganic Chemistry. A
Comprehensive Laboratory Experience” by J. Wiley @ sons. Greek version N.
hadjiliadis, T. Kabanos, D. Kovala-Demertzi, I. Plakatouras, M. Louloudi and s.
Hadjikakou, 2000, 366 pages
5. D. Kovala-Demertzi, A. Domopoulou and M.A. Demertzis«Synthesis,
Spectroscopy and Structures of Complexes of Pd(II) with 4N-Substituted
Derivatives of 2-Αcetylpyridine Thiosemicarbazone” in “Cytotoxic, Mutagenic and
Carcinogenic Potential of Heavy Metals Related to Hyman Environment” Nato ASI
Series, pp. 467-476, ed. N.D. Hadjiliadis, Kluwer Academic Publishers, Dordrecht,
1996
6. D. Kovala-Demertzi "Synthesis and Ρeactivity of Τripalladium clusters" in
METAL CLUSTERS IN CHEMISTRY; Editors: P. Braunstein, L. A. Oro, P. R.
Raithby; WILEY-VCH 1999.
Participation in Research and Educational Projects
Coordinator of Greek research projects (Hrakleits, Pened) on metal-based drugs and bilateral
research projects on metal-based drugs and QSAR (Greece-Italy; Greece-Romania, GreecePoland, Greece-Montenegro)
Participation on the ECTN (European Chemistry Thematic Network)
Participation on the «Multimedia Group» of ECTN. The Working Group on
Multimedia, Open and Distance Learning is one of the Groups of the European
Chemistry Thematic Network; a consortium of about one hundred Chemistry
Departments in Western, Central and Eastern European Universities, which explores
important issues in the chemical sciences from a European perspective. The aims of
the Group are (1) to offer students and lecturers a choice of tools for teaching and
learning; and (2) to encourage chemistry colleagues to increase their use of electronic
tools like networking and multimedia.
Participation on the group "Practical Skills" of ECTN. Τhe objectives of the group
were: To equip chemistry graduates with the skills to do further laboratory research,
and. To train chemistry graduates that are suitable for employment in the non-practical
aspects of commerce. These areas could well be within the chemical industry (e.g.
marketing, administration) but they could also be in non-chemical areas such as
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finance. The practical core chemistry working group believes that practical courses
should be designed to equip graduates with as many transferable skills as possible.
Participation on the COST ELCHEM. ELCHEM is a Metalaboratory to develop elearning technologies in Chemistry, http://www.unil.ch/cost/chem. ELCHEM is a
project of the COST (Collaboration in Scientific and Technical Research) in
Chemistry Action D23 aimed at gathering together European Laboratories working on
the development of problem solving environments and grid computing technologies
useful for implementing e-learning tools for Chemistry, ELCHEM
(http://cost.cordis.lu/src/pdf/D23-e.pdf)..
Socrates-Erasmos, Departmental Coordinator 1998-2010
Former Ph.D students (supervisor)
1. Dr. P. Tauridou, (Ph.D.) Ioannina 1994
2. Dr. A. Domopoulou,(Ph.D.) Ioannina 1998
3. Dr. N Kourkoumelis, (Ph.D) Ioannina 2000
4. V. Dokorou (Master of Science), Ιoannina 2001.
5. L. Papathanasis(Master of Science), Ιoannina 2001
6. Dr. Paras Nath Yadav , (Ph.D), Ioannina 2002.
7. Μ. Tounta (Master of Science), Ioannina 2003.
8. Ch. Kotoglou (Master of Science), Ioannina 2004
9. Ch. Prentjas (Master of Science), Ioannina 2003
10. V. Dokorou, (Ph.D) Ioannina 2004
11. J. Wiecek ( Ph.D.) Ioannina 2006
12. A. Galani (Master of Science), Ioannina 2007
13. A. Alexandratos (Master of Science), Ioannina 2007
14. A. Primikiri (Master of Science), Ioannina 2008
15. M. Staninska (Ph.D.) Ioannina 2009
Current Ph. D students (supervisor)
16. A. Karageorgou (for Master of Science)
17. Maria Dosi (for Master of Science)
18. Anastasia Pournara (for Ph.D.)
19. Stauroula Anastasopoulou (for Ph.D.)
20. Hanna Ahmed (for Ph.D.)
and Postdoctoral students
21. Dr. A. Galani, 2000-2005
22. Dr. N. Dodoff 2002-2003
23. Dr. U. Gangadharmath 2002-2003
24. Dr. Seetharamapa 2004
Current International Co-operations and activities
1. Associate Professor Umberto Russo, Dipartimento de Chimica Inorganica,
Metallorganica ed Analitica, Padua, Italy
2. Professor Alfonso Castineiras, Department of Chemistry, University of Santiago de
Compostela, Santiago de Compostela, Spain
3. Dr. Costel Sarbu, Associate Professor, "Babes-Bolyai" University, Cluj-Napoca, Faculty
of Chemistry and Chemical Engineering, Department of Analytical Chemistry, ClujNapoca, Romania
4. Jerry P. Jasinski, Chair, Professor of Chemistry, Department of Chemistry, Keene State
College, 229 Main Street, Keene, NH 03435-2001
5. Zbigniew Ciunik, D.Sc., Faculty of Chemistry, University of Wroclaw, Department of
Crystallography, 14 F. Joliot-Curie St., 50-383 Wroclaw, Poland
6. Participation on the organizing committee of Scientific International Conferences
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Inorganic Chemistry, Applied
Organometallic Chemistry, Journal of Inorganic Biochemistry, European Journal of
Inorganic Chemistry, Inorganic Chemistry Communications, Inorganica Chimica Acta,
Journal of Organometallic Chemistry, Polyhedron, European Journal of Pharmaceutical
Sciences, Chemistry A European Journal, Life Sciences, Canadian Journal of
Chemistry, Main Group Metal Chemistry, Synlett, Journal of Coordination reviews et
all.
7. Reviewer on International Journals such as,
Invited Lecturer
I have given lectures after invitation at Universities: In Universities of Poland,
University of Poznan, of Lodz, of Wroclav, of Celicia. In Universities of Italy:
University of Padova and at CNRS of Padova. In The University of Cluj-Napoca,
Romania. I have given lectures at Greek Conferences of Chemistry, and Biology and
at International Conferences; at 4th Conference Greek-Cyprian, at 3rd GIPS, στο 3rd
Joint Greek-Italian Meeting on Chemistry of Biological systems and Molecular
Engineering, at 4rd FGIPS, at NATO Advanced Study Institute “Cytotoxic, Mutagenic
and Carcinogenic Potential of Heavy Metals, Including Metals Related to human
Environment”, στο XXth International Conference on Organometallic Chemistry,
2002, at 3rd International Conference of the Chemical Societies of the South-Eastern
European Countries on the chemistry in the New Millennium-an Endless Frontier.
2002, Bucharest,
Invited lecturer at International Conference of Medical Physics, 2003, Poland, at
Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus,
2004 at 8th FGIPS, 2005, at HALCHEM, 2006 and at National Institute Research
(EIE), 2006.
Invited lecturer at Conference “Chemistry and Culture – Euro Mediterranean
Cooperation in Research and Education. Chimie et Culture – Coop. Euro
Méditerranéenne en Recherche et Education, Aristotle Univ. of Thes. 19 & 20 October
2007.
Invited lecturer at 3rd North America – Greece – Cyprus Workshop on Paramagnetic
Materials, 13-15 June, Cyprus, 2009 and at UNIVERSITA’ DI CAMERINO, LLP
ERASMUS / INTENSIVE, Advanced Catalysis and Organometallic Chemistry, 16 to
28 August 2009
Number of published articles and cited publications
132 articles published to professional scientific journals and more than one hundred thirty
(130) announcements to International Conferences and Symposium. From the citation index,
the above publications are cited more than 2000 times.
RESEARCH PUBLICATIONS
132. T. P. Stanojkovic, D. Kovala-Demertzi, A. Primikyri, Isabel Garcia-Santos, A.
Castineiras, Z. Juranic and M. A. Demertzis, ‘Zinc(II) complexes of 2-acetyl
pyridine
1-(4-fluorophenyl)-piperazinyl
thiosemicarbazone:
Synthesis,
spectroscopic study and crystal structures – Potential anticancer drugs’ J. Inorg.
Biochem. 104/4 (2010) 467-476.
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131. J.Wiecek, D. Kovala-Demertzi, Z. Ciunik, J.Wietrzyk, M. Zervou, and M. A.
Demertzis, “Organotin Compound Derived from 3-Hydroxy-2-formylpyridine
Semicarbazone: Synthesis, Crystal Structure, and Antiproliferative Activity”
Bioinorganic Chemistry and Applications, (2010) Article ID 718606, 7,
doi:10.1155/2010/718606.
130. J.Wiecek, D. Kovala-Demertzi, Z. Ciunik, M.Zervou, M. A. Demertzis,
“Diorganotin Complexes of a Thiosemicarbazone, Synthesis: Properties, X-Ray
Crystal Structure, and Antiproliferative Activity of Diorganotin Complexes”
Bioinorganic Chemistry and Applications, (2010) Article ID 867195,
doi:10.1155/2010/867195.
129. T.D. Tzima, G. Sioros, C. Duboc, D. Kovala-Demertzi, V.S. Melissas, Y.
Sanakis, “Multifrequency electron paramagnetic resonance and theoretical studies
of a Mn(II) (S = 5/2) complex: The role of geometrical elements on the Zero Field
Splitting parameters” Polyhedron, 28, 15 (2009) 3257-3264.
128. I. Wiecek, V. Dokorou, Z. Ciunik, D. Kovala-Demertzi *, “Organotin complexes
of pyruvic acid thiosemicarbazone: Synthesis, crystal structures and
antiproliferative activity of neutral and cationic diorganotin complexes”
Polyhedron, 28/ 15 (2009) 3298-3304
127. Alia-Cristina Tenchiu (Deleanu), Ioannis D. Kostas, D. Kovala-Demertzi,
Aris Terzis, "Synthesis and characterization of new aromatic aldehyde/ketone
4-(β-D-glucopyranosyl)thiosemicarbazones" Carbohydrate Research, 344 (2009)
1352–1364.
126. C. Onisor, D. Kovala-Demertzi, M.A. Demertzis, C. Sarbu,* “A comparative
Study of Molecular Lipophilicity Indices of Some Formyl- and Acetylpyridine-3Thiosemicarbazone Derivatives and Various Computed Descriptors” Revista de
Chimie, 60/10 (2009) 1039-1046
125. D. Kovala-Demertzi*, Hadjipavlou-Litina, A. Primikiri, M. Staninska, C.
Kotoglou, M. A. Demertzis Title: Anti-Inflammatory, Antiproliferative, and
Radical-Scavenging Activities of Tolfenamic Acid and Its Metal Complexes,
Chemistry & Biodiversity , 6 (2009) 948-960.
124. D. Kovala-Demertzi,* D. Hadjipavlou-Litina,* M. Staninska, A. Primikiri, C.
Kotoglou and M. A. Demertzis, Anti-oxidant, in vitro, in vivo anti-inflammatory
activity and antiproliferative activity of mefenamic acid and its metal complexes
with manganese(II), cobalt(II), nickel(II), copper(II) and zinc(II) ” Journal of
Enzyme Inhibition & Medicinal Chemistry JEIMC, 24 /3 (2009) 742-752
123. D. Kovala-Demertzi,* V. Dokorou, A. Primikiri, R. Vargas, C. Silvestru, U.
Russo, M. A. Demertzis, “Organotin meclofenamic complexes: Synthesis, crystal
structures and antiproliferative activity of the first complexes of meclofenamic
acid – Novel anti-tuberculosis agents” Journal of Inorganic Biochemistry, 103/ 5
(2009) 738-748
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122. D. Kovala-Demertzi,* A. Papageorgiou, L. Papathanasis, A. Alexandratos, P.
Dalezis, J. R. Miller, M.A. Demertzis,* “In vitro and in vivo antitumor activity of
platinum(II) complexes with thiosemicarbazones derived from 2-formyl and 2acetyl pyridine and containing ring incorporated at N(4)-position: Synthesis,
spectroscopic study and crystal structure of platinum(II) complexes with
thiosemicarbazones, potential anticancer agents” European Journal of Medicinal
Chemistry, 44/3, 1296-1302 (2009)
121. D, Skrzypek, D. Kovala-Demertzi, B. Szymanska-Niewiadomska, N.
Kourkoumelis, M. Staninska, ‘The Synthesis and Spectroscopic Study of Novel
Binuclear Chromium(III) Complex with Pipemidic Acid’ Polish Journal of
Chemistry, 83/3 (2009) 363-371.
120. C. Onisor, D. Kovala-Demertzi, M.A. Demertzis MA, C. Sarbu,* M.V. Diudea,
“QSPR modeling of molecular lipophilicity of some formyl and acetylpyridine-3thio-semicarbazones by topological descriptors” Math-Communications in
Mathematical and in Computer Sciences, 60(3) (2008) 1007-1020
119. D. Kovala-Demertzi,* J. Wiecek, J. C. Plakatouras and Z. Kiunic, “Selfassembly of Dialkyltin(IV) moieties and a thiosemicarbone to a trinuclear
macrocycle and the unpresedented formation of two pseudo-polymorfs with
different cavities” CrystEngComm., 10 (10) (2008) 1291-1295.
118. V. Dokorou, M. A. Demertzis and D. Kovala-Demertzi,* “Recent advances on:
organotin complexes of non-steroidal anti-inflammatory drugs, NSAIDs. Antitubercolosis agents” Pharmakeftiki, 21, I (2008) 1-9 (review article)
117. D. Kovala-Demertzi,* A. Alexandratos, A. Papageorgiou , P. Nath Yadav, P.
Dalezis, and M. A. Demertzis, “Synthesis, characterization, crystal structures, in
vitro and in vivo antitumour activity of palladium(II) and zinc(II) complexes with
2-Formyl
and
2-Acetyl
Pyridine
Ν(4)-1-(2-pyridyl)-piperazinyl
Thiosemicarbazone” Polyhedron, 27(13) (2008) 2731-2738
116. V. N. Dokorou, Dimitra Kovala-Demertzi,* M. Louloudi, A. Silvestru, M. A.
Demertzis, “Synthesis, characterization and catalytic properties of diorganotin
derivatives. Crystal and molecular structure of the first complex of 2-(2-methyl-3nitroanilino)benzoic Acid of 1,2:3,4-di-μ2-2-(2-methyl-3-nitroanilino) benzoatoO,O-1,3-bis-2-(2-methyl-3-nitroanilino)
benzoato-O-1,2,4:2,3,4-diμ3-oxotetrakis[di-methyltin(IV)] ” J. Organomet. Chem., 693(24) (2008) 3587-3592.
115. D. Kovala-Demertzi,* Nikolaos Kourkoumelis,* K. Derlat , J. Michalak , F. J.
Andreadaki, I.
D. Kostas,* “Thiosemicarbazone-derivatised palladium
nanoparticles as efficient catalyst for the Suzuki–Miyaura cross-coupling of aryl
bromides with phenylboronic acid” Inorg. Chim. Acta, 361, 5 (2008) 1562-1565
114. D. Kovala-Demertzi,* A. Galani, N. Kourkoumelis,* J. R. Miller, and M. A.
Demertzis,* “Synthesis, characterization, crystal structure and antiproliferative
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activity of platinum(II) complexes with 2-acetylpyridine-4-cyclohexylthiosemicarbazone” Polyhedron, 26 (2007)2871–2879
113. D. Kovala-Demertzi,* T. Varadinova, P. Genova, P. Souza and M.A.Demertzis,
“Platinum(II) and Palladium(II) Complexes of Pyridine-2- carbaldehyde
Thiosemicarbazone as Alternative anti-Herpes Simplex Virus Agents” Bioinorgac
Chem. Applic. (BCA) art. no. 56165 (2007).
112. N. I. Dodoff, D. Kovala-Demertzi, J. Kuduk-Jaworska, M. Kubiak, and A.
Kochel,
“Structure
of
(dimethyl
sulfoxide-S){glyoxylic
acid}
thiosemicarbazonato(2−)-O,N,S}platinum(II)” Cryst. Res. Technol. 42, No. 5,
(2007) 517 – 521
111. D. Kovala-Demertzi,* A. Boccarelli, M.A. Demertzis and M. Coluccia, “In vitro
antitumour activity of 2-acetylpyridine N(4)-ethyl-thiosemicarbazone and its
platinum(II) and palladium(II) complexes” Chemotherapy, 53 (2007) 148-152
110. D. Skrzypek,* B. Szymanska, D. Kovala-Demertzi,* M. Staninska and N.
Kourkoumelis, “ Synthesis and spectroscopic study of cobalt(II) complexes with
a quinolone family member (pipemidic acid) ” Polish J. Enviromental Studies,
15/44, (2006) 97-99
109. M. A. Demertzis,* P. Nath Yadav, D. Kovala-Demertzi,* “Palladium(II)
Complexes of the Thiosemicarbazone and N-Ethylthiosemicarbazone of 3Hydroxypyridine-2-carbaldehyde: Synthesis, Properties, and X-Ray Crystal
Structure” Helv. Chim. Acta, 89 (9) (2006)1959-1970
108. N. I. Dodoff,* D. Kovala-Demertzi, M. Kubiak, J. Kuduk-Jaworska, A. Kochel,
and G. A. Gorneva, “Dimethyl Sulfoxide Containing Platinum(II) and
Palladium(II) Chelate Complexes of Glyoxylic and Pyruvic Acid
Thiosemicarbazones. A New Class of Cytotoxic Metal Complexes” Z.
Naturforsch. 61b, (2006) 1 – 13
107. D. Skrzypek,* B. Szymanska, D Kovala-Demertzi,* J. Wiecek, E. Talik and M.
A. Demertzis, “Synthesis and spectroscopic studies of iron(III) complex with a
quinolone family member (pipemidic acid) ” Journal of Physics and Chemistry
of Solids, (2006) 2550–2558
106. D. Kovala-Demertzi,* P. Nath Yadav, J. Wiecek, S. Skoulika, T. Varadinova
and M. A. Demertzis,* “Zinc(II) complexes derived from pyridine-2-carbaldehyde
thiosemicarbazone and (1E)-1-pyridin-2-ylethan-1-one thiosemicarbazone.
Synthesis, crystal structures and antiproliferative activity of zinc(II) complexes” J.
Inorg. Biochem. 100/ 9 (2006) 1558-1567.
105. I. D. Kostas,* G. A. Heropoulos, D. Kovala-Demertzi,* P. N. Yadav, J. P.
Jasinski, M. A. Demertzis, F. J. Andreadaki, G. Vo-Thanh, A. Petit and A. Loupy,
“Microwave-promoted Suzuki–Miyaura cross-coupling of aryl halides with
phenylboronic acid under aerobic conditions catalyzed by a new palladium
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complex with a thiosemicarbazone ligand” Tetrahedron Letters, e 47/26, (2006)
4403-4407
104. J. Seetharamappa,* N. Motohashi and D. Kovala-Demertzi, “Application of
Phenothiazine Derivatives and other Compounds for the Determination of Metals
in Various Samples” Current Drug Targets, (7) 9, (15) (2006)1107-1121
103. D. Kovala-Demertzi*, “Recent advances on non-steroidal anti-inflammatory
drugs, NSAIDs: Organotin complexes of NSAIDs” (review article
J. Organom. Chem. 691 (2006)1767–1774
102. N. Kourkoumelis,* A. Hatzidimitriou, D. Kovala-Demertzi,* “Synthesis and
Crystal
Structure
of
trichlorodimethyl(2-aminopyrimidinium)tin(IV),
[SnMe2Cl3(H-2APY)] ” Crystallography Reports Vol. 51, Suppl. 1, (2006) pp.
S76–S78
101. B. Szymanska, D. Skrzypek,* D. Kovala-Demertzi,* M. Staninska, M.A.
Demertzis “Synthesis and spectroscopic study of copper(II) and manganese(II)
complexes with pipemidic acid”, Spectrochim. Acta, Part A 63 (2006) 518–523
100. D. Kovala-Demertzi,* V. Dokorou, R. Kruszynski, T. J Bartczak, J. Wiecek, and
M.A. Demertzis,.“Condensation reaction of dimethyltin(IV) oxide with {2-[(2,3dichlorolphenyl)amino] benzoic acid}.Synthesis and study of a novel dimeric
tetraorganodistannoxane”, Z. Αnorg. Αllgem.Chem. (ZAAC) 631(12) (2005) 24812484
99. D. Kovala-Demertzi,* U. Gangadharmath, M. A. Demertzis, Y. Sanakis, “Crystal
structure and spectral studies of a novel manganese(II) complex of 4-Phenyl-2acterylpyridine thiosemicarbazone. Extended network of [Mn(Ac4Ph)2] via
hydrogen bond linkages and π-π interactions” Inorg. Chem Commun. 8 (7),
(2005) 619-622
98. D. Kovala-Demertzi,* Vaso N. Dokorou, Jerry P. Jasinski, Adam Opolski,
Joanna Wiecek, Maria. Zervou, Mavroudis A. Demertzis,* “Organotin
flufenamates. Synthesis, characterization and antiproliferative activity of organotin
flufenamates” J. Organomet. Chem. 690 (2005)1800–1806
97. Ioannis D. Kostas,* Fotini J. Andreadaki, D. Kovala-Demertzi,* Ch. Prentjas, and
Mavroudis A. Demertzis “Suzuki-Miyaura cross-coupling reaction of aryl
bromides and chlorides with phenylboronic acid under aerobic conditions
catalyzed by palladium complexes with thiosemicarbazone ligands” Tetrahedron
Letters, 46 (12) (2005) 1967-1970
96. E. Pontiki, D. Hadjipaulou,* I. Hadjidakis, A.M. Demertzis and D. KovalaDemertzi “Quantitative Structure-Activity Relationships of Substituted (S)Phenylpiperidines as Preferential Dopamine Autoreceptor Antagonists Using
Neural Networks” J. Enzyme Inhibition and Medicinal Chemistry 20(1) (2005)
5–12
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95. D. Kovala-Demertzi, D. Skrzypek,* B. Szymanska , A. Galani, M.A. Demertzis,
“EPR spectroscopic study of a dinuclear copper(II) complex of tolfenamic acid”
Inorg. Chim. Acta, 358 (1) (2005)186-190
94. M.L. Główka, M. Błaszczyk, Ch. Prentjas and D. Kovala-Demertzi, “Synthesis
and
structure
of
two
thiocarboxypyrazolic
acid
derivatives”
Polish J. Chem. 78 (2004) 2013-2022
93. B. P. Kamat, J. Seetharamappa* and D. Kovala-Demertzi, “Spectrofluorometric
Study of the Interaction of Coumarin Derivatives with Bovine Serum
Albumin”
Journal of Photoscience Vol. 11(2) (2004) pp. 65-69
92. I. Kurikou, S. Hadjikakou, D. Kovala-Demertzi, K. Viras, and T.
Mauromoustakos,* “Effects of non-steroidal anti-inflammatory drugs in membrane
bilayers” Chemistry and Physics of Lipids, 132 (2004) 157–169
91. N.I. Dodoff, R. Varga, D. Kovala-Demertzi, “Crystal structure of N-3pyridinylmethanesulfonamide
and
trans-diiodobis(N-3pyridinylmethanesulfonamide) platinum(II)” Z. Naturforsch., B (9): (2004)10701076
90.
E. Siapi, T. Mavromoustakos,* D. Kovala-Demertzi, C. Vidjeluc, M.A.
Demertzis, “The thermal effects of platinum (II) and palladium (II) complexes
with 2-acetyl pyridine and pyridine-2-carbaldehyde N(4)-ethyl-thiosemicarbazones
in membrane bilayers.” Thermochimica Acta 424 (1-2), 53-58 (2004)
89. L. Papathanasis, M.A. Demertzis,* P. Nath Yadav, D. Kovala-Demertzi,* Ch.
Prentjas, A. Castiñeiras, S. Skoulika, and D. X. West, “Palladium(II) and
Platinum(II) complexes of 2-hydroxy acetophenone N(4)-Ethylthiosemicarbazone.
Crystal structure and description of bonding properties” Inorg. Chim. Acta 357
(2004) 4113-4120
88. G. Roman, A. Ch. Pappas, D. Kovala-Demertzi, and M.I Prodromidis,*
"Preparation of a 2-(4-fluorophenyl)indole modified xerogel and its use for the
fabrication of screen-printed electrodes for the electrocatalytic determination of
sulfide" Analytica Chimica Acta 523(2004) 201-207
87. D. Kovala-Demertzi,* A. Koutsodimou, A. Galani, S. K. Hadjikakou, M. A.
Demertzis,*
M.
Xanthopoulou,
J.
R.
Miller,
C.S.
Frampton,
“Diphenylbis(Hpiroxicam)tin(IV), [Ph2Sn(Hpir)2]” Applied Organomet. Chem.
18 (2004) 501-502
86. V. Dokorou, D. Kovala-Demertzi,* J.P. Jasinski, A. Galani and M.A. Demertzis,
“Synthesis, Spectroscopic Studies and Crystal Structures of Phenylorganotin
Derivatives with [Bis(2,6-dimethylphenyl)amino]benzoic acid. Novel Antituberculosis Agents” Helvetica Chimica Acta, 87 (2004) 1940-1950
10
85. C. Sarbu, M.A. Demertzis, D. Kovala-Demertzi, “Fuzzy principal component
analysis and its applications in QSAR studies” Rev. Chim-Bucharest, 55 (5)
(2004) 297-300
84. C. Sarbu C, C. Vijdeluc, M.A. Demertzis and D. Kovala-Demertzi, “UV-VIS
spectral information of platinum(II) and palladium(II) complexes with pyridine-2carboxaldehyde-thiosemicarbazone and their correlation with antineoplastic and
cytogenetic effects” Rev. Chim-Bucharest, 55 (7) (2004) 478-482
83 A. Galani, D. Kovala-Demertzi,* N. Kourkoumelis, A. Koutsodimou, V.Dokorou,
Z. Ciunik, Umberto Russo, Mavroudis A. Demertzis,* . “Organotin adducts of
indomethacin: synthesis, crystal structures and spectral characterization of the first
organotin complexes of indomethacin” Polyhedron, 23 (2004)2021-2030.
82. D. Kovala-Demertzi,* P. N. Yadav, M. A. Demertzis, J. P. Jasiski, F. J.
Andreadaki and I. D. Kostas,* “First use of a palladium complex with a
thiosemicarbazone-based ligand as catalyst precurs or for the Heck reaction”
Tetrahedron Letters 45 (2004) 2923–2926
81. D. Kovala-Demertzi,* A. Galani, M.A. Demertzis,* S. Skoulika and C. Kotoglou,
“Binuclear copper(II) complexes of Tolfenamic. Synthesis, crystal structure,
spectroscopy and superoxide dismutase activity” J. Inorg. Βιοchem. 98(2004)
358–364.
80. N. Kourkoumelis, M. A. Demertzis, D. Kovala-Demertzi,* A. Koutsodimou, A.
Moukarika “Preparations and spectroscopic studies of organotin complexes of
diclofenac” Spectrochimica Acta: A 60 (2004) 2253-2259
79. V.Dokorou, M.A. Demertzis, J. P. Jasinski, and D. Kovala-Demertzi,* “Synthesis
and spectroscopic studies of diorganotin derivatives with 2-[(2,6dimethylphenyl)amino]benzoic acid. Crystal and molecular structure of the first
complexes of 2-[(2,6-dimethylphenyl)amino]benzoic acid. Crystal and molecular
structures of 1,2:3,4-di-μ2-2-[(2,6-dimethylphenyl)amino]-benzoatoO,O-1,3-bis-2[(2,6-dimethylphenyl)amino]benzoato-O-1,2,4:2,3,4-diμ3-oxo-tetrakis[dibutylltin(IV)] and bis-2-[(2,6-dimethylphenyl)amino]benzoato-di-n-butyltin(IV)”,
J. Organomet. Chem. 689 (2004) 317–325
78 E. Mioglou, Z. Iakovidou, B. Karagianni, D. Mourelatos, B. Gourtsa, D. KovalaDemertzi, V. Dokorou, N. Kourkoumelis, M. Demertzis,. “SCEs as a genotoxicity
index of organometallic complexes of Sn(IV) with known non-steroidal antiinflammatory drugs” Επιστημονική επετηρίδα τμήματος ιατρικής Α.Π.Θ., 30, 1,
(2003) 26-30
77. C. Sarbu, MA. Demertzis MA, D. Kovala-Demertzi, “Chromatographic behaviour
and lipophilicity of Pd(II) and Pt(II) complexes of py-2-carbaldehyde
tiosemicarbazone with potential biological activity” Rev. Chim-Bucharest 54 (10)
(2003) 799-801
11
76. A. Galani, M. A. Demertzis, Maciej Kubicki and D. Kovala-Demertzi,*
“Organotin-Drug Interactions. Organotin adducts of lornoxicam, Synthesis and
Characterization of the first complexes of lornoxicam” Eur. J.Inorg. Chem, 9,
(2003)1761-1767
75. P. Nath Yadav ,M. A. Demertzis,* D. Kovala-Demertzi,* S. Skoulika and D. X.
West, “Palladium(II) complexes of 4-formylantipyrine N(3)-substituted
thiosemicarbazones: first example of X-ray crystal structure and description of
bonding properties” Inorg. Chim. Acta,349, 30-36 (2003)
74. D. Kovala-Demertzi,* M. A. Demertzis, E. Filiou, A. A. Pantazaki, P.N. Yadav, J.
R. Miller, Y. Zheng and D. A. Kyriakidis* “Platinum(II) and palladium(II)
complexes with 2-Acetyl pyridine 4N-ethyl thiosemicarbazone able to overcome
the cis-Platin resistance. Structure, antibacterial activity and DNA strand
breakage” Biometals, 16 (2003) 411–418
73. D. Kovala-Demertzi,* M. A. Demertzis, J. R. Miller, C. S. Frampton, J. P. Jasinski
and
D
X.
West,
“Structure
of
Bis(2-acetylpyridine
3hexamethyleneiminylthiosemicarbazonato) palladium(II), a Potential Antitumor
Complex”, J. Inorg Biochem., 92 (2002) 137-140
72. T. Mavromoustakos, I. Kyrikou, A. Kapou and D. Kovala-Demertzi, “Effects of
NSAIDs in membrane bilayers” in Drug Discovery and design: Medical Aspects,
Volume 55 of Biomedical and Health Research, Editors: J. Matsoukas, T.
Mavromoustakos; IOS Press, pp. 150-157, 2002
71. D. Kovala-Demertzi,* V. Dokorou, Z Ciunik, N. Kourkoumelis and M.A.
Demertzis, “Organotin Mefenamic Complexes: Preparations, spectroscopic
studies and crystal structure of a triphenyl ester of mefenamic acid. Novel antituberculosis agents” Applied Organometallic Chemistry, 16 (2002) 360-368
70. P. N. Yadav, M.A. Demertzis,* D. Kovala-Demertzi,* A. Castineiras and D.X.
West, “Synthesis, solution and spectral studies of palladium (II) complexes with2hydroxyacheteophenone N3propypthiosemicarbazone. Crystal structure of a
tripalladium complex” Inorg. Chim Acta, 332 (2002) 204-209
69. V. Dokorou, Z. Ciunik, U. Russo and D. Kovala-Demertzi,* " Synthesis, crystal
structures and spectroscopic studies of diorganotin derivatives with mefenamic
acid.
Crystal
and
molecular
structures
of
1,2:3,4-di-μ2-2-[(2,3dimethylphenyl)amino]-benzoato-O,O-1,3-bis-2-[(-[(2,3dimethylphenyl)amino]benzoato-O-1,2,4:2,3,4-diμ3-oxo-tetrakis[dimethyltin(IV)] and 1,2:3,4-di-μ2-2-[(-[(-[(2,3-dimethylphenyl)amino]-benzoatoO,O-1,3-bis-2-[(-[(-[(2,3-dimethylphenyl)amino]benzoato-O-1,2,4:2,3,4-diμ3oxo-tetrakis[di-n-butyltin(IV)]" J. Organom Chem., 630, 205-214 (2001)
68. D. Kovala-Demertzi,* M. A. Demertzis, J. R. Miller, C. Papadopoulou, C.
Dodorou, G. Filousis, "Platinum(II) complexes with 2-acetyl pyridine
12
thiosemicarbazone. Synthesis, crystal structure, spectral properties, antimicrobial
and antitumor activity" J. Inorg. Biochem. 86 (2001) 555-563
67. T. Varadinova,* D.Kovala-Demertzi, M. Rupelieva, M. Demertzis and P. Genova,
"Cytotoxicity and antiviral activity of Pt(II) and Pd(II) complexes of pyridine-2carbaldehyde thiosemicarbazane" Acta Virologica, 45 (2001) 87-94
66. Z. Iakovidou, E. Mioglou, D. Mourelatos,* A. Kotsis, M.A. Demertzis, A.
Papagoergiou, P.Nath Yadav and D. Kovala-Demertzi,"Cytogenetic and
Antineoplastic Effects of Platinum(II) and Palladium(II) Complexes With 2Acetylpyridine thiosemicarbazone" Anticancer Drugs, 12 (2001) 65-70
65. D. Kovala-Demertzi,* N. Kourkoumelis, A. Koutsodimou, A. Moukarika, E.
Horn, and E. R. T. Tiekink, "Synthesis and spectroscopic studies of diorganotin
derivatives with tolfenamic acid. Crystal and molecular structure of the first
complex of tolfenamic acid, 1,2:3,4-di- 2-2-[(3-chloro-2-methylphenyl)amino]benzoato-O,O-1,3-bis-2-[(3-chloro-2-methylphenyl)amino]benzoato-O1,2,4:2,3,4-di- 3-oxo-tetrakis[di-n-butyltin(IV)]" J. Organomet. Chem. 620
(2001) 194-201
64. M. A. Demertzis,* S. K. Hadjikakou, D Kovala-Demertzi,* A. Koutsodimou and
Maciej Kubicki "Organotin-Drug Interactions. Organotin adducts of tenoxicam,
Synthesis and Characterisation of the first organotin complex of tenoxicam"
Helvet. Chim. Acta, 83 (2000) 2787-2801
63. S. K. Hadjikakou, M. A. Demertzis, M. Kubicki, D. Kovala-Demertzi,*
"Organotin Adducts with Pyrimidinethione. The Crystal Structure of Dimethyldi
(pyrimidine-2-thiolato)tin(IV)
and
Diphenyldi(pyrimidine-2-thiolato)tin(IV)
Applied Organomet. Chem., 14 (2000) 727-734.
62. C. Sarbu, M.A. Demertzis and D. Kovala-Demertzi,"Estimation of Lipophilicity
of Some Metallic Complexes of Diclofenac with Potentially Anti- Inflammatory
Activity by Thin Layer Chromatography" Acta Chromatographica, 10 (2000)
61. D. Kovala-Demertzi,* P. Nath Yadav, M. A. Demertzis, M. Coluccia, "Synthesis,
crystal structure, spectral properties and cytotoxic activity of platinum(II)
complexes of 2-acetyl pyridine and pyridine-2-carbaldehyde N(4)-ethylthiosemicarbazones" J. Inorg. Biochem., 78/4 (2000) 347-354
60. D. Kovala-Demertzi ,* N. Kourkoumelis, M. A. Demertzis, John R. Miller, C.
Frampton, and D. X. West, "Trinuclear palladium(II) complexes with 4-methoxy2-hydroxyacetophenone N(4)-dimethylthiosemicarbazone. Synthesis, spectral
studies and crystal structure of a tripalladium complex Eur. J. Inorg. Chem,
(2000) 727-734
59. D. Kovala-Demertzi,* "Transition metal complexes of diclofenac with potentially
interesting anti-inflammatory activity" J. Inorg. Biochem., 79/1-4 (2000)153-157
13
58. Z. Iakovidou, E. Mioglou, D. Mourelatos, A. Kotsis, A. Papagoergiou, D. KovalaDemertzi, M.A. Demertzis and V. Varagi,"Human Lymphocyte Cytogenetic
Alterations as an Index of Action of New Potentially antineoplastic Pd(II) and
Pt(II) complexes" Helliniki Iatriki, 65, 4-6 (2000) 336-340
57.
D. Kovala-Demertzi,* "Metal ion-drug interactions. Synthesis, structure and
biological activity of metal complexes of diclofenac" Pharmakeutiki, 12, III-IV
(1999) 113-118
56. D. Kovala-Demertzi “Synthesis and Ρeactivity of Τripalladium clusters" in
METAL CLUSTERS IN CHEMISTRY; Editors: P. Braunstein, L. A. Oro, P. R.
Raithby; WILEY-VCH 1999
55. N. Kourkoumelis, D. Kovala-Demertzi* and E. R.T. Tiekink,* "Crystal and
molecular structure of 1,2:3,4-di-μ-2[(2,6dichlorephenyl)amino] benzeneacetatoO,O-1,3-bis(2[(2,6dichlorephenyl) amino]benzeneacetato-O-1,2,4;2,3,4-di- μ3oxo-tetrakis[di-n-butyltin(IV)]: {[Bu2Sn(O2CCH2C4H4N(H)C6H3Cl2]2O}2" Z.
Kristallogr. 214, 758-762 (1999)
54. D. Kovala-Demertzi, M. A. Demertzis, P. Nath Yadav, A. Castineiras and D.X.
West,* "Preparation, spectral and structural characterization of (2benzoylpyridineN(4)methylN(4) phenylthiosemicarbazonato) chloropalladium(II)"
Transition Met. Chem, 24, (1999) 642-647
53. S. K. Hadjikakou, M.A. Demertzis, J. R. Miller and D. Kovala-Demertzi,*
“Synthesis and Structural Characterization of the First Organotin Complex of
Piroxicam. An
extended Network system via Non-Hydrogen, Hydrogen
Bonding Linkages and C-H-- π Contacts” J. Chem. Soc. Dalton Trans, (1999)
663-669
52. A. Theodorou, M. A. Demertzis, D. Kovala- Demertzi,* E. E.Lioliou, A.A.
Pantazaki and
D. A. Kyriakidis,* “Copper(II) complexes of diclofenac:
Spectroscopic studies and DNA strand breakage” Biometals, 12 (1999)167-172
51. D.Kovala-Demertzi,*J. R. Miller, N. Kourkoumelis, S. K. Hadjikakou and M. A.
Demertzis, “Palladium(II) and platinum(II) complexes of pyridine-2-carbaldehyde
thiosemicarbazone with potential biological activity. Synthesis, structure and
spectral properties. Extended network via hydrogen bond linkages of
[Pd(PyTsc)Cl] ” Polyhedron, 18 (1999)1005-1013
50. D. Kovala-Demertzi,* M.A. Demertzis, A. Castineiras and D.X. West,
“Palladium(II)
complexes
of
2-acetyland
2-formylpyridine
3hexamethyleneiminylthiosemicarbazones; a synthetic, spectral and structural
study” Polyhedron, 17/21(1998) 3739-3745
49. D. Kovala-Demertzi,* M.A. Demertzis, V. Varagi, A. Papageorgiou, D.
Mourelatos, E. Mioglou, Z. Iakovidou, A. Kotsis “Antineoplastic and Cytogenetic
Effects on platinum and palladium complexes with Pyridine-2-carboxaldehyde
Thiosemicarbazone” Chemotherapy, 44 (1998) 421-426
14
48. D. Kovala-Demertzi,* N. Kourkoumelis, P. Tavridou, A. Moukarika, P. D.
Akrivos, and U. Russo, “Spectroscopic Studies for Adducts of 2-aminopyrimidine
with Tin(IV) Halides and Tin(II) Chloride. Cis-trans Isomerism in
Tetrabromobis(2-aminopyrimidine)tin(IV)” Spectrochimica Acta, Part A, 54/12
(1998) 1801-1809
47. M. Konstandinidou, A. Kourounaki, L. Hadjipetrou,* D.Kovala-Demertzi, S.
Hadjikakou and M.A. Demertzis, “Antiinflammatory Properties of Complexes of
Diclofenac with Transition Metals” J. Inorg. Biochem., 70, (1) (1998) 63-69
46. D. Kovala-Demertzi,* N. Kourkoumelis, D. X. West, J. Valdιs-Martνnez , and S.
Hernαndez-Ortega, “A Trinuclear Palladium(II) Complex with Bridging 2Ηydroxyacetophenone N(4)-Εthylthiosemicarbazone Ligands.
An Unusual
Dimethylformamide Promoted Deprotonation and Aggregation” Eur. J. Inorg.
Chem. (1998) 861-863
45. Α. Domopoulou, A. Michaelidis, S. Skoulika* and D. Kovala-Demertzi,
“Crystallization of an Unstable Molecular Compound Using a Tailor-Made
Additive” J. Crystal Growth, 191 (1998)166-168
44. D. Kovala-Demertzi,* S.K. Hadjikakou, M.A. Demertzis and Y. Deligiannakis,
“Metal Ion-Drug Interactions. Preparation and Properties of Manganese(II),
Cobalt(II) and Nickel(II) Complexes of Diclofenac with Potentially Interesting
Anti-inflammatory Activity. Behavior in the Oxidation of 3,5-di-tert-butyl-ocatechol” J. Inorg. Biochem., 69 (1998) 223-229
43. A. Koutsodimou, D. Kovala-Demertzi, and N. Katsaros “DNA-Binding Studies of
Magnesium(II), Calcium(II), Barium(II) and its ATP complexes”
J. Coord. Chem., 43 (1998) 1-12
42. D. Kovala-Demertzi,* A. Domopoulou, G. Valle, M.A. Demertzis and A.
Papageorgiou, “Palladium(II) complexes of 4N-Methyl and 4N-Ethyl and 4NPhenyl 2-Acetylpyridine Thiosemicarbazones. Crystal Structure of Cloro(4Nmethyl-2-actylpyridine thiosemicarbazonato)palladium(II). Synthesis, Chemicophysical Study, in vitro and in vivo Antitumour activity” J. Inorg. Biochem., 68
(1997) 147-156
41. D. Kovala-Demertzi,* A. Domopoulou, M. A. Demertzis, A. Papageorgiou, and
D. X. West, “Palladium(II) complexes of 2-acetylpyridine N(4)-propyl, N(4)Dipropyl-, and 3-Hexamethyleiminylthiosemicarbazones with Potentially
Interesting Biological Activity. Synthesis, Physico-chemical Properties, Antifungal
and in vitro Antitumor Activity” Polyhedron, 16, 20 (1997) 3625-3633
40. A. Papageorgiou, Z. Iakovidou, D. Mourelatos,* E. Mioglou, L. Boutis, A. Kotsis,
D.Kovala-Demertzi, A. Domopoulou, D.X. West and M.A. Demertzis,
“Antineoplastic and Cytogenetic Effects of Complexes of Pd(II) with 4NSubstituted Derivatives of 2-Acetyl-Pyridine-Thiosemicarbazone” Anticancer
Res, 17 (1997) 247-252
15
39. D. Kovala-Demertzi,*A. Domopoulou and M.A. Demertzis “Synthesis,
Spectroscopy and structures of Complexes of Pd(II) with 4N-Substituted
Derivatives of 2-Αcetylpyridine Thiosemicarbazone” in “Cytotoxic, Mutagenic
and Carcinogenic Potential of Heavy Metals Related to Hyman Environment”
Nato ASI Series, pp. 467-476, ed. N.D. Hadjiliadis, Kluwer Academic Publishers,
Dordrecht, 1996
38. D. Kovala-Demertzi,* A. Theodorou, M.A. Demertzis, C.P. Raptopoulou and A.
Terzis,
“Synthesis
and
Characterization
of
Tetrakis--2[(2,6dichlorophenyl)amino]benzeneacetodiaquodicopper(II)
dihydrate
and
Tetrakis--2-[(2,6dichlorophenyl)amino]benzeneacetodimethylformamido
dicopper(II)” J. Inorg. Biochem., 65 (1997) 151-157
37. D. Kovala-Demertzi,* V. Varagi, M.A. Demertzis, C.P. Raptopoulou and A.
Terzis, “2-Acetylpyridinium 4N-phenylthiosemicarbazone Monohydrochloride
Hydrate (1:1:1.25)” Acta Cryst. Sect. C52, (1996) 2027-2029
36. D. Kovala-Demertzi,* A. Domopoulou, M.A. Demertzis, J. Valdes-Martinez,* G.
Espinosa-Perez, D.X. West,* M.M. Salberg, G.A. Bain and P.B. Bloom,
“Structures and spectral properties of Palladium(II) complexes of 2-acetylpyridine
N(4)-Dimethylthiosemicarbazone” Polyhedron, 15/15 (1996) 2587-2596
35. N. Kourkoumelis, A. Hadzidimitriou and D. Kovala-Demertzi,* “The crystal
structure of di-aminopyrimidinium tetraphenyldichloro (-oxo)distannato” J.
Organomet. Chem., 514 (1996) 163-167
34. D. Kovala-Demertzi,* P. Tauridou, U. Russo and M. Gielen, “Adducts of
Organotin(IV), Tin(IV) and Tin(II) Halides with 1-Methyl-imidazolin-2(3H)thione (Hmimt) and Imidazoline-2(1,3H)-thione (Himt). Synthesis, Spectroscopic
(Infrared, Mössbauer and 1H-, 13C-, 119Sn- NMR) Studies and in vitro Antitumour
Activity” Inorg.Chim. Acta, 239/1-2 (1995) 175-181
33. D. Kovala-Demertzi,* P.Tauridou, A. Moukarika, J.M. Tsangaris, C.P.
Raptopoulou and A.Terzis, “Synthesis and Characterization of Tin(IV) and
Organotin(IV) Cyclosarcosylsarcosine
Adducts. The Crystal Structure of
Catena-bis-μ-cyclosarcosylsarcosine Dicloro Diphenyl Tin(IV)” J. Chem. Soc.
Dalton, (1995) 123-128
32. Tauridou, U. Russo, D. Marton, G.Valle and D. Kovala-Demertzi,*"Synthesis and
Chemico-physical Characterization of Tin(IV) Adducts with 2- Imidazolidone”
Inorg. Chim. Acta, 231, 1-2 (1995) 139-145
31. R.S. Drago, D. Kovala-Demertzi and D.C. Ferris, “Analysis of Solvent Effects
Induced in Physicochemical Properties of Coordination Compounds”
J. Coord. Chem., 32 (1994) 145-153
30. D. Kovala-Demertzi,* A. Domopoulou, M.Α. Demertzis, C.P. Raptopoulou and
A.Terzis “Coordinating Properties of 2-Acetylpyridine Thiosemicarbazone.
16
Palladium(II)
Complexes with Neutral and Deprotonated Ligand. X-Ray
Structure of Bromo (2-Acetylpyridine Thiosemicarbazonato) Palladium(II)”
Polyhedron, 13, 12 (1994) 1917-1925
29. A. Koutsodimou, N. Katsaros* and D. Kovala-Demertzi “The interaction of
Rhodium(III) with DNA by Circular Dicroism Studies. A Comparative Behaviour
of Dimethyltin(IV) and Thalium(I)” Trans, Met. Chem., 19 (1994) 260-264
28. D. Kovala-Demertzi *and S.P. Perlepes,* “Coordination Compounds of
Platinum(II) and Palladium(II) with Benzotriazoles as Ligands” Trans. Met.
Chem., 19 (1994) 7-11
27.
D. Kovala-Demertzi,* “Coordinating Behaviour of Pyridylhydrazones.
Complexes of Rh (III) with Methyl-2-Pyridyl
and
Phenyl-2-Pyridyl
Hydrazones and
N,N-Dimethyl Hydrazones” Bull. Soc. Chim. Belg.,102, 3
(1993) 193-201
26. D. Kovala-Demertzi,* A. Domopoulou, A. Michaelidis* and A. Aubry, “The
Crystal
Structure
of
[(Dibromophenyl-2-pyridyldimethylhydrazone)
Palladium(II)]” J. Coord. Chem.(A) 30 (1993) 265-271
25. D. Kovala-Demertzi,* P.Tauridou, J.M.Tsangaris and A. Moukarika “Organotin
and Tin(IV) Derivatives of Pyrimidine- 2-Thione” Main, Group, Met. Chem., 5,
16 (1993) 315-328
24. P. Tauridou, U. Russo,* G. Valle and D. Kovala-Demertzi, “The crystal Structure
of Dicloro-bis (2-imidazolidone) dimethyltin” J. Organomet. Chem, 460 (1993)
C16-18
23. D. Kovala-Demertzi,* D. Mentzafos and A. Terzis, “Metal Complexes of the
Antiinflammatory
Drug,
Sodium
[2(2,6Dichlorophenyl)Amino]Phenyl]Acetate (Diclofenac Sodium). Molecular and
Crystal Structure of Cadmium Diclofenac” Polyhedron, 11 (1993)1361-1371
25. D. Kovala-Demertzi,* A. Michailides,* and A. Aubry, “Palladium Complexes of
2-Acylpyridines. The Crystal Structure of Dibromo Bis [phenyl-2-pyridylketone]
Palladium (II)” Inorg.Chim. Acta, 194 (1992)189-194
21. G.Maistralis, N. Katsaros, S.P. Perlepes and D. Kovala-Demertzi,* “Coordinating
Properties of Isoorotic Acid” Jour. Inorg. Biochem., 45 (1992) 1-12
20. D. Kovala-Demertzi,* P. Kurkou and I. Zakharova, “The Synthesis and
Characterization of Pyrimidine-2-Thione Complexes of Pd (II)” Polyhedron, 10,
13 (1991) 1507-1512
19. D. Kovala-Demertzi,* “Gold(III) Complexes of 2-Amino-4,6-Dimethyl
pyrimidine” Bull. Chem. Soc. Jpn., 64 (1991) 744-746
17
18. J.M. Tsangaris,* E. Voureca and D. Kovala-Demertzi, “The Circular Dicroism of
Cu (II) and Ni (II) Complexes of L-Pipecolic Acid in Connection with the
Decahexant Rule” Acta Chim. Hung., 2 (1991) 213-217
17. D.Kovala-Demertzi,* “Platinum (II) and Platinum (IV) Complexes of 2-Amino4,6-Dimethyl Pyrimidine” Trans. Met. Chem., 15, 1 (1990) 23-26
16. D. Kovala-Demertzi,* S.P. Perlepes* and G. Lazaras, “Syntheses and Study of
Rh (III), Pd (II), Pt (II), Ag (I) and Au (III) Complexes of 1-Methyl-3,4Diphenylpyrazole” Bull. Sos. Chim. Belg., 98, 7 (1989) 503-512
15. S. Perlepes,* D. Kovala-Demertzi,* S. Skarimbas and S. Paraskevas “The
Coordination Chemistry of Hydrazones. Variation of Product Identity as a
Function of Metal Ion Ligand Reaction Ratio, Stereochemistry Studies and
Thermal Investigation of Mn (II) , Fe (II), Ni (II), Cu (II ) Cd (II) and Hg (II) of
2-Acetyl Pyridine Hydrazone Complexes” Therm. Acta, 147 (1989) 153-174
14. D. Kovala-Demertzi,* M.A. Demertzis and J.M. Tsangaris, “Complexes of
Vanadium (III) with Amino Acids. Part II. Synthesis and Circular Dichroism
in Water Solutions of the Complexes of
L-Aspartic acid, L-Glutamic, LAsparagine and L-Glutamine” Bull. Soc. Chim. Franc., 5 (1988) 793-798
13. D. Kovala-Demertzi and D. Nicholls,* “Compexes of the Platinum Metals with
Hydrazones. Palladium (II) Complexes with 2-Acetyl and 2-Benzoylpyridine
Hydrazone”Jour. Coord. Chem. Soc. A, (1988) 297-303
12. M. Louloudi, D. Kovala-Demertzi and N. Hadjiliadis,* “Cobalt (II), Nickel (II),
Copper (II) and Zink (II) Complexes of Thiazolidine” Bull. Soc. Chim. Belg., 97,
2 (1988) 91-97
11. D. Kovala-Demertzi,* J.M. Tsangaris and H.O. Desseyn “Spectroscopic Study of
the Pd (II) Complexes with 2-Amino-4,6-Dimethyl Pyrimidine” Bull. Soc. Chim.
Belg., 96, 1 (1987) 7-14
10. D. Kovala -Demertzi* and J.M. Tsangaris and H.O. Desseyn, “ Study of the Pd(II)
Complexes with 2-Hydroxy Pyrimidine Hydrochoride” Bull. Soc. Chim. Belg.,
96, 4 (1987) 335-336
9. D. Kovala-Demertzi * and J.M. Tsangaris, “Comlexes of 2,4- Diamino 5-(3,4,5Trimethoxybenzyl) Pyrimidine (trimethoprim) with Pd (II)” Inorg. Chim. Acta,
(Bioin.Chem.) 125, 3 (1986) L31-33
8. D. Kovala-Demertzi, M.A. Demertzis and
J.M. Tsangaris,*“Complexes of
Vanadium(III) with Amino Acids I. Synthesis and Circular Dichroism in Water
Solutions of the Complexes of L-Serine and L-Threonine and L-Leucine” Bull.
Soc. Chim. Franc. 4 (1986) 558-563
18
7. M.A. Demertzis, D. Kovala-Demertzi, E. Vansant, G.J. Peeters and E.
Vanderheyden “The Absorption of Sulfur Compounds on Cu(II)Y Zeolite” Bull.
Soc. Chem. Belg. , 95, 3 (1986) 145-150
6 D. Kovala- Demertzi, J.M. Tsangaris and N. Hadjiliadis,. “Complexes of 2,4Diamino-5-(3,4,5- trimethoxybenzyl )Ryrimidine (Trimethoprim) with Pt (II), Rh
(III) and Au (III)” Jour. Less. Comm. Met., 115 (1986) 1-8
5. D. Kovala -Demertzi, J.M. Tsangaris and N. Hadjiliadis, “Complexes of Cu (II), Ni
(II), and Co (II) with Aliphatic and Aromatic Mono and Diamines” Chimica
Chronica (New Series), 14 (1985) 3-19 (review in Greek)
4. D. Kovala-Demertzi, D. Nicholls* and K. Tracey, “Coordination compounds
Derived from Dimethylhydrazones of Cyclohexane-1,2-Dione,2-Acetyl,2Benzoylpyridine” Inorg. Chim. Acta, 85 (1984) 143-146
3. D. Kovala -Demertzi, J.M. Tsangaris and N. Hadjiliadis,* “Complexes of
Aminobenzylamines.Part II. Complexes of o-Aminobenzylamine with Palladium
(II) and Platinum (II)” Trans. Met. Chem., 9 (1984) 77-80
2. D. Kovala-Demertzi and D. Nicholls,* “Cobalt (II) and Zink (II) Complexes of 2Acetyl and 2-Benzoylpyridine Hydrazones” Inorg. Chim. Acta, 73 (1983)37-40
*
1. D. Kovala-Demertzi, J.M. Tsangaris and Ν. Hadjiliadis, “Complexes of
Aminobenzylamines.Part I. Complexes of o-Aminobenzylamine with Copper (II),
Cobalt (II), and Nickel (II)” Trans. Met. Chem., 8(3) (1983) 140-146 Correct.
Trans. .Met.Chem.,8(5), 319 (1983)