Online Appendix for the following November 17, 2009 JACC article TITLE: Long-Term Ambrisentan Therapy for the Treatment of Pulmonary Arterial Hypertension AUTHORS: Ronald J. Oudiz, MD, Nazzareno Galiè, MD, Horst Olschewski, MD, Fernando Torres, MD, Adaani Frost, MD, Hossein A. Ghofrani, MD, David B. Badesch, MD, Michael D. McGoon, MD, Vallerie V. McLaughlin, MD, Ellen B. Roecker, PHD, Brooke C. Harrison, PHD, Darrin Despain, MS, Christopher Dufton, PHD, Lewis J. Rubin, MD, for the ARIES Study Group APPENDIX ARIES-1 and ARIES-2 Study Group 1. Abrahamovych, O., Lviv State Medical University, Lviv, Ukraine 2. Allen, R., University of California - Davis Medical Group, Sacramento, CA 3. Amuchastegui, M., Hospital Privado Centro Medico de Cordoba, Córdoba, Argentina 4. Badesch, D., University of Colorado Health Sciences Center, Denver, CO 5. Baratz, D., Pulmonary Associates, Phoenix, AZ 6. Barbera, JA., Hospital Clinic, Barcelona, Spain 7. Barst, R., New York Presbyterian Hospital, New York, NY 8. Behr, J., Medizinische Klinik und Poliklinik I, München, Germany 9. Ben-Dov, I., The Pulmonary Institute, Tel-Hashomer, Israel 10. Black, C., Royal Free Hospital, London, United Kingdom 11. Bortman, G., Clinica Independencia Munro, Buenos Aires, Argentina 12. Cardoso, A., Hospital Universitario Clementino Fraga Filho, Ilha Fundâo, Brazil 13. Carroll, J., University of Iowa Hospitals & Clinics, Iowa City, IA 14. Castro, P., Hospital Clinico Universidad Catolica, Santiago, Chile 15. Chakinala, M., Washington University School of Medicine, St. Louis, MO 16. Channick, R., UCSD Medical Center, La Jolla, CA 17. Chatkin, J., Hospital Sao Lucas de Pontificia Universidade Católica, Porto Alegre, Brazil 18. Chazova, IE., A.L. Myasnikov Clinical Cardiology Institute, Moscow, Russia 19. Ciruzzi, J., Hospital Castro Rendón-Neuquén, Neuquén, Argentina 20. Colque, R., Hospital Italiano de Córdoba, Córdoba, Argentina 21. Coughlin, G., Royal Free Hospital, London, United Kingdom 22. Czuriga, I., University of Debrecen, Debrecen, Hungary 23. Delcroix, M., University Hospital of Leuven, Leuven, Belgium 24. de Souza, R., Hospital das Clinicas da FMUSP, Sao Paulo, Brazil 25. Diez, F., Hospital Italiano de Rosario, Santa Fe, Argentina 26. Donoso, H., Hospital San Juan de Dios, Santiago, Chile 27. Gene, R., Sanatorio Otamendi, Buenos Aires, Argentina 28. Engel, P., The Lindner Clinical Trial Center, Cincinnati, OH 29. Fairman, P., Virginia Commonwealth University, Richmond, VA 30. Feldman, J., Arizona Pulmonary Specialists, Phoenix, AZ 31. Figuereido Campos, F., Hospital Madre Teresa, Belo Horizonte, Brazil 32. Foley, R., University of Connecticut Health Center, Farmington, CT 33. Frost, A., Baylor College of Medicine, Houston, TX 34. Galie, N., University of Bologna, Bologna, Italy 35. Garcia, H., Mt. Sinai Medical Center, Miami, FL 36. Ghofrani, H., University of Giessen Lung Center, Giessen, Germany 37. Gomez-Sanchez, M., Hospital Universitario 12 de Octubre, Madrid, Spain 38. Gossage, J., Medical College of Georgia, Augusta, GA 39. Guzman, L., Sanatorio Allende, Córdoba, Argentina 40. Hausson, P., Johns Hopkins University, Baltimore, MD 41. Hill, N., Tufts - New England Medical Center, Boston, MA 42. Karlocai, K., National Koranyi Institute for TBC and Pulmonology, Budapest, Hungary 43. Karpenko, MA., Research Institute of Cardiology, St. Petersburg, Russia 44. Keogh, A., St. Vincent's Hospital, Darlinghurst, Australia 45. Kleber, FX., Unfallkrankenhaus Berlin, Berlin, Germany 46. Klinger, J., Rhode Island Hospital, Providence, RI 47. Kopitsa, N., Institute of Therapy, Kharkov, Ukraine 48. Kovalenko, V., Academy of Medical Sciences, Kiev, Ukraine 49. Kramer, M., Pulmonary Institutue, Petach Tikva, Israel 50. Landzberg, M., Brigham & Women’s Hospital, Boston, MA 51. Lang, I., Allgemeines Krankenhaus, Wien, Austria 52. Mathier, M., University of Pittsburgh Medical Center Presbyterian, Pittsburgh, PA 53. McGoon, M., Mayo Clinic, Rochester, MN 54. Meyer, G., Complexo Hospitalar Sanata Casa de Porto Alegre, Porto Alegre, Brazil 55. Mubarak, K., Wayne State University, Detroit, MI 56. Murali, S., University of Pittsburgh Medical Center Presbyterian, Pittsburgh, PA 57. Naeije, R., Erasmus University Hospital, Bruxelles, Belgium 58. Netiazhenko, V., Academy of Medical Sciences, Kiev, Ukraine 59. Olschewski, H., Medizinische Universitatsklinik, Graz, Austria 60. Oudiz, R., LA Biomedical Research Institute at Harbour-UCLA Medical Center, Torrance, CA 61. Park, M., Ochsner Clinic Foundation, New Orleans, LA 62. Peacock, A., Scottish Pulmonary Vascular Unit, Glasgow, United Kingdom 63. Pepke-Zaba, J., Papworth Hospital NHS Trust., Cambridge, United Kingdom 64. Perna, E., Instituto de Cardiologia J.F. Cabral, Corrientes, Argentina 65. Peterson, W., Scott & White Hospital, Temple, TX 66. Pinzetta, J., Instituto del Corazón Denton A. Cooley, Buenos Aires, Argentina 67. Podolec, P., Klinika Chorob Serca i Naczyn, Kraków, Poland 68. Polyvoda, S., Zaporozhye Medical Institute, Zaporozhye, Ukraine 69. Porcille, R., UAI Hospital Universitario, Buenos Aires, Argentina 70. Pulido, T., Instituto Nacional de Cardiología Ignacio Chávez, México, Mexico 71. Ramirez Rivera, A., Unidad De Investigación Clínica en Medicina, Monterrey, Nuevo León, Mexico 72. Robbins, I., Vanderbilt University Medical Center, Nashville, TN 73. Robbins, M., University of Virginia Charlottesville, VA 74. Saydain, G., Wayne State University, Detroit, MI 75. Schilz, R., University Hospitals of Cleveland, Cleveland, OH 76. Semernin, E., Chair of Internal Diseases, St. Petersburg, Russia 77. Shapiro, S., West Los Angeles HealthCare Center, Los Angeles, CA 78. Sonoe Ota Arakaki, J., Universidade do Estado de Sao Paulo – UNIFESP, Sao Paulo, Brazil 79. Sulica, R., Beth Israel Medical Center, New York, NY 80. Tereshchenko, SN., Moscow State Medical Stomatologic University, Moscow, Russia 81. Test, V., Scott & White Hospital, Temple, TX 82. Torbicki, A., Instytut Gruzlicy i Chorob Pluc w Warszawie, Warsaw, Poland 83. Torres, F., University of Texas Southwestern Medical Center, Dallas, TX 84. Ubaldini, J., Hospital Británico-Buenos Aires, Buenos Aires, Argentina 85. Vazquez, J., HIGA Hospital Interzonal General de Agudos Oscar Allende, Mar del Plata, Argentina 86. Ventura, H., Ochsner Clinic Foundation, New Orleans, LA 87. Vonk Noordegraaf, A., Vrije Universiteit Medical Center, Amsterdam, Netherlands 88. Waxman, A., Massachusetts General Hospital, Boston, MA 89. Zagolín, M., Instituto Nacional del Torax, Santiago, Chile 90. Zwicke, D., Heart Care Associates, LLC/ Wisconsin Electrophysiology Group, Milwaukee, WI