Publications::
:‫البحوث المنشورة‬
1. Wang Z., Masternak MM, Al-Regaiey KA, Bartke A. Adipocytokines and the
Regulation of Lipid Metabolism in Growth Hormone Transgenic and Calorie
Restricted Mice. Endocrinology, 148:2845-2853. 2007.
2. Al-Regaiey KA, Masternak MM, Bonkowski MS, Panici J, Kopchick JJ, and
Bartke A, Effects of Caloric Restriction and Growth Hormone Resistance on
Insulin-Related Intermediates in the Skeletal Muscle. Journal of Gerontology,
62:18-26. 2007.
3. Bartke A, Masternak MM, Al-Regaiey KA, Bonkowski MS., Effects of dietary
restriction on the expression of insulin-signaling-related genes in long-lived
mutant mice. Interdiscip Top Gerontol.;35:69-82. 2007
4. Bonkowski MS, Rocha JS, Masternak MM, Al Regaiey KA, Bartke A., Targeted
disruption of growth hormone receptor interferes with the beneficial actions of
calorie restriction. Proc Natl Acad Sci (PNAS) U S A. 103:7901-7905, 2006
5. Wang Z., Al-Regaiey KA., Masternak MM., Bartke A., Adipocytokines and
Lipid Levels in Ames Dwarf and Caloric Restricted Mice, J Gerontol A Biol Sci
Med Sci. 61:323-331, 2006
6. Masternak MM, Al-Regaiey KA, Lim MM, Jimenez-Ortega V, Panici JA,
Bonkowski MS, Kopchick JJ, Wang Z, Bartke A. Caloric restriction and growth
hormone receptor knockout: Effects on expression of genes involved in insulin
action in the heart. Exp Gerontol. 41:417-429, 2006
7. Masternak MM, Al-Regaiey KA, Del Rosario Lim MM, Jimenez-Ortega V,
Panici JA, Bonkowski MS, Kopchick JJ, Bartke A. Effects of caloric restriction
and growth hormone resistance on the expression level of peroxisome
proliferator-activated receptors superfamily in liver of normal and long-lived
growth hormone receptor/binding protein knockout mice. J Gerontol A Biol Sci
Med Sci, 60:1394-1398. 2005
8. Michal M. Masternak, Khalid A. Al-Regaiey, Michael S. Bonkowski, Jacob A.
Panici and Andrzej Bartke Effect of every other day feeding diet on gene
expression in normal and in long-lived Ames dwarf mice Exp Gerontol. 40:491497, 2005
9. Liou Y. Sun, Khalid Al-Regaiey, Michal M. Masternak, Jian Wang and Andrzej
Bartke. Local Expression of GH and IGF-1 in the Hippocampus of GH-deficient
long-lived Mice. Neurobiol Aging. 26:929-937. 2005
10. Michal M. Masternak, Khalid A. Al-Regaiey, Marc Michael Del Rosario Lim,
Vanesa Jimenez-Ortega, Jacob A. Panici, Michael S. Bonkowski and Andrzej
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Bartke. Effects of caloric restriction on insulin pathway gene expression in the
skeletal muscle and liver of normal and long-lived GHR-KO mice Exp Gerontol.
40:679-684. 2005
11. Masternak MM, Al-Regaiey KA, Del Rosario Lim MM, Bonkowski MS, Panici
JA, Przybylski GK, Bartke A. Caloric restriction results in decreased expression
of peroxisome proliferator-activated receptor superfamily in muscle of normal
and long-lived growth hormone receptor/binding protein knockout mice. J
Gerontol A Biol Sci Med Sci. 60:1238-45. 2005
12. Khalid A. Al-Regaiey, Michal M. Masternak, Michael Bonkowski, Liou Sun and
Andrzej Bartke. Insulin Related Signaling in the Liver of Wild-type and longlived Growth Hormone Receptor Knockout Mice: Alteration by Long-term
Caloric Restriction. Endocrinology 146: 851 – 860. 2005
13. Krishnamurthy J, Torrice C, Ramsey MR, Kovalev GI, Al-Regaiey K, Su L,
Sharpless NE. 2004 Ink4a/Arf expression is a biomarker of aging. J Clin Invest.
114:1299-12307, 2004.
14. Argentino DP, Dominici FP, Al-Regaiey K, Bonkowski MS, Bartke A, Turyn D.
Effects of long-term Caloric Restriction on Early Steps of the Insulin Signaling
System in the Mouse Skeletal Muscle. J. Gerontol. 60:28-34. 2005
15. Argentino DP, Dominici FP, Munoz,MC, Al-Regaiey K, Bartke A, Turyn D.
Effects of long-term Caloric Restriction on Glucose homeostasis and on the first
Steps of the Insulin Signaling System in Skeletal Muscle of Normal and Ames
Dwarf mice. Exp. Gerontol.;40:27-35. 2005
16. Michal M. Masternak, Khalid Al-Regaiey, Michael S. Bonkowski, Jacob Panici,
Liou Sun, Jian Wang, Grzegorz K. Przybylski, Andrzej Bartke. Divergent effects
of caloric restriction on gene expression in normal and long-lived mice – The
Journals of Gerontology, 59:784-788. 2004
17. Miller RA, Chang Y, Galecki AT, Al-Regaiey K, Kopchick JJ, Bartke A. Gene
expression patterns in calorically restricted mice: partial overlap with long-lived
mutant mice. Mol Endocrinol. 16:2657-2666. 2002
:‫كتب‬
Book Chapters:
1. Andrzej Bartke, Khalid Al-Regaiey, Michal M Masternak Pituitary Function
Through the Ages, 2004, volume 8, 127-139 Impacts of Hormones and
Nutrition on Aging, HypoCCS Series, Edited by R Ross and EM Erfurth
BioScientifica Ltd, Bristol, UK.
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2. Andrzej Bartke, Michal M Masternak, Khalid Al-Regaiey, Michael Bonkowski
Effects of Dietary Restriction on the Expression of Insulin Signaling-related
Genes in Long-lived Mutant Mice, Mechanisms of Dietary Restriction in Aging
and Disease, edited by Charles Mobbs, Kelvin Yen , and Patrick Hof, published
by Karger Spring. Vol. 35, 2007
Abstracts:
‫ملخصات‬
Khalid A Al-Regaiey, Michal M Masternak, Zhihui Wang, Jacob Panici and Andrzej
Bartke. Effects of Caloric Restriction and Growth Hormone Treatment on InsulinRelated Intermediates in The Liver, Endocrine Society 90th Annual Meeting, San
Francisco, CA 15-19 June, 2008.
Khalid A Al-Regaiey, Michal M Masternak, Zhihui Wang, Jacob Panici and Andrzej
Bartke. Effects of Caloric Restriction and Growth Hormone Treatment on InsulinRelated Intermediates in The Skeletal Muscle, Experimental Biology 2008, San Diego,
CA, 5-9 April, 2008
Krishnamurthy J, Torrice C, Ramsey MR, Al-Regaiey K, Sharpless NE. 2004 Ink4a/Arf
expression, Regulation and response to caloric restriction in rodent aging. Molecular
Genetics of Aging, Cold Spring Harbor, NY, October 6-10 2004.
Krishnamurthy J, Torrice C, Ramsey MR, Kovalev GI, Al-Regaiey K, Su L, BonnerWeir S, Sharpless NE. Expression of the Ink4a/Arf tumor suppressor locus is a biomarker
and effector of aging. Molecular Genetics of Aging, Cold Spring Harbor, NY, October 610 2004.
Alregaiey KA, Hauck S, and Bartke A 2002 Effects of caloric restriction on antioxidant
enzymes in long-lived GHR/BP-KO mice. The 84th Annual Meeting of the Endocrine
Society, San Francisco, CA, P-308
Bonkowski, M.S., Alregaiey, K.A., and Bartke, A. Effects of Caloric Restriction in
Long-Lived, Growth Hormone (GH) resistant GHR/GHBP- Knockout (KO) Mice.
ENDO; 2002, P3-307, pg 507 Abstract
Michal M. Masternak , Khalid A. Al-Regaiey, Michael S Bonkowski, Andrzej Bartke
The effect of growth hormone receptor knockout and caloric restriction on expression of
genes related to insulin signaling in mice American Aging Association - 33rd Annual
Meeting Molecular Mechanisms of Aging: As Modulated by Genes, Hormones and
Oxidative Events June 4-7, 2004 St Petersburg, Florida
Khalid Al-Regaiey, Michal M. Masternak, Michael Bonkowski, Liou Sun, Andrzej
Bartke. Effects of long-term caloric restriction on wild-type and growth hormone receptor
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knockout mice. American Aging Association - 33rd Annual Meeting Molecular
Mechanisms of Aging: As Modulated by Genes, Hormones and Oxidative Events June 47, 2004 St Petersburg, Florida
Pamenter R.W., Bonkowski M.S., Rocha J.S., Masternak M.M., Al-regaiey K., Bartke A.
Growth hormone receptor/binding protein-null mice indicate that growth hormone plays a
role in normal bone function in young, adult, and aged mice. American Society for Bone
and Mineral Research 26 Annual Meeting October 1-5 2004
Liou Y. Sun, Khalid Al-Regaiey, Michal M. Masternak, Jian Wang and Andrzej Bartke
Hippocampal GH and IGF-1 expression in GH-deficient mice
American Aging Association - 33rd Annual Meeting Molecular Mechanisms of Aging: As
Modulated by Genes, Hormones and Oxidative Events June 4-7, 2004 St Petersburg,
Florida
Zhihui Wang, K.A. Al-Regaiey, M.M.Masternak, A.Bartke
Expression of genes related to insulin sensitivity and lipid metabolism in Ames dwarf and
caloric restricted mice
American Aging Association - 33rd Annual Meeting Molecular Mechanisms of Aging: As
Modulated by Genes, Hormones and Oxidative Events June 4-7, 2004 St Petersburg,
Florida
Bonkowski M.S., Pamenter R., Rocha J.S., Al-Regaiey K., Masternak M.M., Bartke A.
Long term caloric restriction does not deleteriously impact bone characteristics or body
composition in normal and long lived growth hormone receptor/binding protein null
mice. American Society for Bone and Mineral Research 26 Annual Meeting October 1-5
2004
M. M. Masternak, M. S. Bonkowski, K. A. Al-Regaiey, A. Dabrowska, D. Zaczek, G.K.
Przybylski, A. Bartke. Expression of genes related to insulin signaling in growth
hormone receptor knockout, Ames dwarf, and caloric restricted mice, GSA’s 56th Annual
Scientific Meeting, San Diego, CA
Andrzej Bartke, Khalid Al-Regaiey, Michal M Masternak. Impacts of Hormones and
Nutrition on Aging. Publication of manuscripts from the 8th International HypoCCS
Meeting Pituitary Function Trough the Ages
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