Biotechnology Course Syllabus 2009-2010 School Year Course Title: Biotechnology Room: B-111 Instructor: Kristin Donley Credits: 5/semester Office Hours: by appointment Office: B-107 Email: Kristin.donley@bvsd.org Web site: http://bvsd.org/schools/monarchhigh/Pages/default.aspx Designated Grade Levels: 10th and higher Course Duration: 1 or 2 semesters Prerequisite/Recommendation: Biology Class Materials/Supplies: 1. 2. 3. 4. 5. 6. 7. 8. 3-ring notebook or folder; Journal (spiral or composition book) Calculator and ruler Black or blue pens, pencils, paper email account (You have free school account) Goggles or Safety Glasses (will use throughout high school and college) $15 for one semester/$25 for year long laboratory fee (for consumable lab supplies) Biozone Workbook (Microbiology and Biotechnology ISBN: 978-1-877462-12-2 ($8.95 each)) PREP Account (details provided at a later date) Course Description: Students will explore the fundamental principles of biotechnology, career pathways and biotechnology business applications (medical, pharmaceutical, and agricultural). Topics of study include: plant tissue culturing; DNA, RNA, and protein technologies; genetic diagnostics; healthcare and pharmaceuticals; food processing (GMO’s); fermentation technology; energy and environmental management; forensic science; cloning; stem cells; and bioethics. Laboratory activities reinforce concepts and principles presented. Self-sufficiency and responsibility in work habits required. (See outline of specific topics) Instructional Strategies: Students will be exposed to a variety of teaching pedagogies such as demonstrations, lectures, inquiry laboratory experiments, skill worksheets, class debates, field trips, guest presenters, literature reviews, tests, and computer technology. Process skills in scientific reading and writing, listening, following directions, hypothesizing, observing, recording, evaluating, analyzing data, and cooperating with others will be emphasized throughout the course. Learning Materials: Biozone workbook: Microbiology and Biotechnology ISBN: 978-1-877462-12-2 ($8.95 each). I will also provide various supplemental handouts (e.g., articles from various lab manuals, textbooks and magazines such as Time, Scientific American and Discover) during the year. Assessment: For your Monarch transcript, your grade will be a weighted average between summative (~50%), formative (~40%) and prep and practice (10%). I will be giving you reading assignments and problem sets/review guides for each chapter/unit that we study. These assignments will often include notes, vocabulary, concept mastery problems and short essays as well as critical thinking problems. These study guides will provide you with what you are expected to know, understand, demonstrate and apply to attain mastery of the unit’s objectives. Use your resources wisely! Also, all laboratory activities will have a lab a write-up which could include a full report, PowerPoint, poster, or analysis questions. The extensiveness of these reports will vary. You will be provided details/rubric for each lab on each lab assignment. Additionally, I will assign a few projects during the year. Details of each project and their grading scale will be distributed at the appropriate time. Class Grading Categories: Grades will be based on attainment of the essential learnings for each standard. Laboratory Work (Formative) Tests and Quizzes (Formative & Summative) Final Exam (Summative) Homework/Class Activities & Projects (Formative & Prep/Production) ~40% ~30% ~20% ~10% Grade Scale: Letter Grade Percentage GPA Scale Class Rules: A 90 – 100% 4 B 80 – 89% 3 C 70 – 79% 2 D 60 – 69% 1 F Below 60% 0 Academic Honor Code: (This is a biggie!) You are to submit only your own work manufactured from your own thoughts and processes. Anything used from another source must be appropriately cited! Students failing to comply with the “honor code” are subject to disciplinary action through the instructor and Monarch’s administration. No warning is necessary from the instructor. Please note that your signature on the class contract indicates your awareness and acceptance of this policy. Classroom Conduct: At all times, conduct yourself in a manner that promotes learning and ensures safety. Treat yourself, your classmates, and your classroom with compassion and respect. Safety in the lab is essential! Unsafe practices or behavior of any kind will result in suspension from the lab and loss of credit. (See separate handout of Lab Safety Guidelines for further clarification.) Absent Policy: Work is to be turned in on its due date, even if you attend school for only part of the day. For an excused absence (from the entire day), it is your responsibility to obtain missed materials, notes, handouts, etc. and make up assignments within two days. Anything assigned prior to the excused day, is your responsibility to make sure it gets turned in on time! For work missed during that day, you have two days from the day of your return to see me about scheduling make-up labs, projects, quizzes, or tests; otherwise these assignments will become a zero. I highly suggest if you know about a scheduled absence that you make arrangements prior to missing class! Because of the fast pace and rigor of this class, I also highly suggest that you attend all classes, for attendance will be to your benefit! Do not schedule dentist appointments, doctor’s appointments, etc. during class time to avoid missing valuable information! For unexcused absences, as per school policy, no credit can be given for assignments not turned in or activities done during that day of class. However, be aware that you are still responsible for the material. I will give extensions so loing as they are not abused; please discuss individual situations with your instructor before an assignment is due! Remember that most late work will not be accepted after a set deadline unless student talks to instructor and makes other arrangements! The Instructor considers this document a contract between the student and instructor. If you have any questions, please feel free to contact me via Kristin.donley@bvsd.org or at 303-665-5888 X4589. Email is the best form of communication because the voicemail regularly “acts” up, and I don’t get messages quickly. Additionally, there is a class web site where grades and other class information can be obtained: http://bvsd.org/schools/monarchhigh/Pages/default.aspx . I look forward to this year and getting to know both the students and their parents/guardians. Biotechnology Topics Microorganisms and Biotechnology Microbial Groups Features of Microbial Groups The Structure of Viruses Replication in Bacteriophages Replication in Animal Viruses Bacterial Cells Growth in Bacterial Populations Review of Bacterial Structure Antimicrobial Drugs Antibiotic Resistance Evolution in Bacteria Fungi Techniques in Microbial Culture Strain Isolation Serial Dilution Uses of Microorganisms Energy Resources Sewage Treatment Industrial Microbiology Industrial Production of Enzymes Putting Enzymes to Work Applications of Enzymes White Wine Production Red Wine Production Beer Brewing Bread Making Cheese Making Yoghurt Making Cloning and Cell Culture Plant Tissue Culture Stem Cells and Tissue Engineering Xenotransplantation Cloning by Embryo Splitting Cloning by Nuclear Transfer The Human Cloning Debate Genetic Manipulation The Nature of GMOs Restriction Enzymes Ligation Gel Electrophoresis Polymerase Chain Reaction Gene Cloning Using Plasmids Transgenic Organisms Genetically Modified Plants Using Recombinant Bacteria The Ethics of GMO Technology Biotechnology in Medicine Production of Human Proteins Monoclonal Antibodies Types of Vaccines Edible Vaccines Gene Therapy Vectors for Gene Therapy Gene Delivery Systems Bioinformatics and Disease research Genome Research Manual DNA Sequencing Automated DNA Sequencing Genome Analysis DNA Profiling Using PCR DNA Profiling Using Probes DNA Chips Investigating Genetic Biodiversity The Human Genome Project Genome Projects Forensic Science Careers and Bio-tech Business Simulation