Answers for Practice Questions Biochem 1. • Channel proteins allow molecules to pass through the membrane freely. • Carrier proteins allow specific molecules to pass through the membrane freely (1 mark) or actively (1 mark). • Cell recognition proteins with attached carbohydrates identify cells to the immune system. • Receptor proteins pass chemical signals across the cell membrane. • Enzymatic proteins allow reactions to occur at the membrane. 2. • The DNA molecule’s double helix is unwound. • Hydrogen bonds between nucleotides are broken, separating the strands of the helix. • Complementary nucleotides attach to the original nucleotides in each strand. • New nucleotides are linked together by bonds thus forming new strands complementary to the original strands. 3. • Substrates bind to enzymes at the active sites. • Mercury ions denature the enzymes. • This results in a change in the shape of the active sites. • The substrates cannot bind to the active sites. • The rate of reaction decreases. Digestion 1. • The stomach is acidic while the small intestine is basic. • The stomach contains protein molecules while the small intestine contains peptides and amino acids. • The stomach contains fat molecules while the small intestine contains fatty acid and glycerol molecules. • The small intestine contains glucose molecules while the stomach does not. • Any valid enzyme addition (e.g., pepsin is found in the stomach while trypsin is found in the small intestine). 2. • Salivary amylase digests starch. • Pancreatic amylase digests starch. (either one for 1 mark) AND • starch to maltose (1 mark) • maltase digests maltose (1 mark) • maltose to glucose (1 mark) Circulation 1. • has thick walls that resist blood pressure • has elastic fibres to allow stretching and recoil • when the arteriole contracts, this increases blood pressure to the remainder of the body • endothelium layer provides smooth surface (less friction) for blood movement • has sphincters which control blood flow to the capillary beds • has smooth muscles which control blood flow to the capillary beds Respiration 1. • Compared to the umbilical vein, blood in the umbilical artery has higher concentrations of: – carbon dioxide – hydrogen ions – bicarbonate ions – reduced hemoglobin – carbaminohemoglobin – urea. • Compared to the umbilical artery, blood in the umbilical vein has higher concentrations of: – oxyhemoglobin – glucose – amino acids – nucleotides. 2. • Blood at area X contains high levels of bicarbonate ions (HCO3– ) while blood at area Y contains low levels of HCO3– . • Blood at area X contains high levels of carbaminohemoglobin (HbCO2 ) while blood at area Y contains low levels of HbCO2 . • Blood at area X contains high levels of reduced hemoglobin (HHb+ ) while blood at area Y contains low levels of HHb+ . • Blood at area X contains high levels of carbon dioxide (CO2 ) while blood at area Y contains low levels of CO2 . • Blood at area X contains low levels of nutrients while blood at area Y is rich in nutrients. • Blood at area Y contains high levels of oxyhemoglobin (HbO2 ) while blood at X contains lower levels of HbO2 . 3. • increased concentration of carbon dioxide (CO2 ) • increased concentration of bicarbonate ions (HCO3– ) • increased acidity • decreased concentration of oxygen (O2 ) Nervous 1. • Calcium ions flow into the synaptic ending, causing the contractile proteins to contract. • As they contract, they pull the vesicles to the surface of the presynaptic membrane. • They merge with the membrane and release neurotransmitters into the cleft. • The neurotransmitters diffuse across the cleft and fit into receptor sites on the postsynaptic membrane. • By fitting into receptor sites, an action potential is generated in the postsynaptic membrane. • The neurotransmitters are either destroyed by enzymes or reabsorbed. 2. • Calcium ions are required to cause the contraction of protein molecules in the synaptic ending. • Neurotransmitter molecules are not secreted. • Without neurotransmitters, the sodium gates in the postsynaptic membrane would not open. • Depolarization of the postsynaptic membrane would not occur. • No new nerve impulse would be produced. 3. • Calcium ions move into the cell. • They interact with contractile proteins and pull the vesicles to the surface of the presynaptic membrane. • The vesicles merge with the presynaptic membrane and release neurotransmitters into the synaptic cleft. • The neurotransmitters diffuse across the cleft. • The neurotransmitters fit into receptor sites, causing the postsynaptic membrane to depolarize. Urinary 1. • Dehydration results in an increased solute concentration in the blood (1 mark) which is sensed by osmoreceptors in the hypothalamus. (1 mark) • The osmoreceptors signal the posterior pituitary gland to increase antidiuretic hormone (ADH) secretion. (1 mark) • Increased ADH stimulates the kidney to increase the reabsorption of water (1 mark), decreasing the solute concentration in the blood. (1 mark) • The osmoreceptors stimulate thirst, causing the person to increase water intake, thereby decreasing solute concentration in the blood. (1 mark) 2. • Aldosterone stimulates the distal convoluted tubule to reabsorb more sodium ions from the filtrate. (1 mark) • Water follows these ions osmotically, raising blood volume. (1 mark) • Increased volume increases blood pressure (1 mark), which forces more blood plasma into the tissue fluids (1 mark). • This increased volume also decreases osmotic pressure (1 mark), causing a decrease in tissue fluid reabsorption, causing swelling (1 mark). Reproduction 1. X: • Increasing levels of estrogen cause increased secretion of luteinizing hormone (LH) from the pituitary. • Increasing levels of estrogen cause decreased secretion of follicle-stimulating hormone (FSH) from the pituitary. • Increasing levels of estrogen cause an increase in the thickness of the endometrium. (1 mark) AND Y: • High levels of progesterone cause a decrease in the secretion of LH from the pituitary. (1 mark) • High levels of progesterone from the ovary cause the endometrium to increase in thickness, become vascularized and to produce mucus. (1 mark) 2. • In males, follicle-stimulating hormone (FSH) targets the cells of the seminiferous tubules (1 mark) and causes sperm production (1 mark). • In females, FSH targets the ovaries (1 mark) and causes follicle development (1 mark). • In males, luteinizing hormones (LH) targets the interstitial cells (1 mark) and causes testosterone production (1 mark). • In females, LH targets the corpus luteum (1 mark) and causes the production of progesterone (1 mark). • In females, the LH “spike” causes the follicle to release the ovum (ovulation). 3. • The hypothalamus secretes gonadotropic-releasing hormone (GnRH). • GnRH stimulates the anterior pituitary to secrete luteinizing hormone (LH). • LH stimulates the interstitial cells of the testes to produce testosterone. • As the level of testosterone rises, there is negative feedback exerted on the hypothalamus. • As the level of testosterone rises, there is negative feedback exerted on the anterior pituitary. • The secretion of LH slows down and testosterone decreases.