REQUEST FOR NOMINATIONS
University of Chicago
Chicago K12 Scholar Awards
Applications Due on Monday, June 30th, 2011
E-mail application materials to Lestra Cole, ITM Pilot Program Administrator
(lcole@bsd.uchicago.edu)
The University of Chicago has funding for five K12 Scholar positions, CTSA (one), Paul Calabresi
Career Development in Clinical Oncology (three) and Multidisciplinary Training in Asthma
Genetics and Genomics (one), that will provide substantial salary support for faculty-level clinical
and translational scientists near the beginning of their investigative careers. CTSA appointment will
run from September 1, 2011 through August 31, 2013. Scholars to this program are appointed on
a two year basis, and are not guaranteed continued funding in subsequent years. Paul Calabresi
appointments will run from August 1, 2011 through July 31, 2013. Appointments of Scholars to
this program is for a minimum of 2 years but individual scholars can be supported for up to 3 years;
basic science scholars wishing to train in clinical research may be supported for up to 3 years.
Training in Asthma Genetics and Genomics appointment will run from July 1, 2011 through
June 30, 2013. Scholars to this program are appointed on a two year basis, and are not guaranteed
continued funding in subsequent years.
CTSA – Research topics can relate to any aspect of clinical and/or translational research, relevant
to any patient population and disease group, and employing any suitable research approach.
However, potential relevance to the understanding or treatment of human disease must be
demonstrated.
Paul Calabresi – Research topics can relate to any aspect of clinical and/or translational
research, relevant to any patient population and disease group, and employing any suitable research
approach. However, potential relevance to clinical oncology therapeutic research must be
demonstrated.
Multidisciplinary Training in Asthma Genetics and Genomics – Research topics can relate to any
aspects of clinical and/or translational research, relevant to any patient population and disease
group, and employing any suitable research approach. However, potential relevance to asthma or
other lung diseases and incorporation of genetic or genomic approaches must be
demonstrated.
OVERVIEW OF THE CTSA K12 MECHANISM
CTSA K12 Scholars are to be relatively new investigators, at the faculty level of Assistant Professor
or Instructor, who are committed to a career in clinical and/or translational research. In certain
circumstances, Associate Professors can apply if they are newly entering the field of clinical and
translational research. The goal of the CTSA K12 Scholar mechanism is to produce
accomplished clinical/translational researchers capable of utilizing the tools of clinical and/or
basic research to improve the understanding or treatment of human disease. Investigators must
have a full time faculty-level appointment; graduate students or post-doctoral trainees are not
eligible. In addition, candidates are expected to assemble a multidisciplinary mentoring committee of
senior advisors/mentors. All K12 Scholars are expected to enroll in the Masters of Science in Health
Studies or other applicable Masters Degree program offered at the University unless they have
already had equivalent training in clinical or translational research. Tuition for the Masters degree will
be waived for K12 Scholars.
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OVERVIEW OF THE PAUL CALABRESI SCHOLARS K12 MECHANISM
Paul Calabresi K12 Scholars are to be relatively new investigators, at the faculty level of Assistant
Professor or Instructor, who are committed to a career in clinical and/or translational research. The
goal of the program is to train scholars to 1) primarily perform clinical oncology therapeutic
research that develops and tests scientific hypotheses based on fundamental and clinical
research findings; 2) design and test hypothesis-based, clinical therapeutic protocols and
adjunct biological analyses and for clinician candidates to administer all phases (i.e.,
pilot/Phase I, Phase II, and Phase III) of cancer therapeutic clinical trials, and (3) conduct
cancer therapeutic research in team research settings in which basic research and clinical
scientists collaborate and interact to expedite the translation of basic science research
discoveries into patient-oriented therapeutic cancer research. Investigators must have a facultylevel appointment; graduate students or post-doctoral trainees are not eligible. In addition,
candidates are expected to assemble a multidisciplinary mentoring committee of senior
advisors/mentors. K12 Scholars are expected to enroll in the Masters of Science in Health Studies or
other applicable Masters Degree program offered at the University unless they have already had
equivalent training in clinical or translational research. Tuition for the MS degree will be waived for
K12 Scholars.
OVERVIEW OF THE MULTIDISCIPLINARY TRAINING IN ASTHMA GENETICS AND GENOMICS
K12 MECHANISM
The Asthma Genetics and Genomics K12 scholars are to be relatively new investigators, at the
faculty level of senior fellow, Instructor, or Assistant Professor, who are committed to a career in
clinical and/or translational research. This is a multidisciplinary program that trains young scientists to
use state of the art methods in genetics and genomics to develop new diagnostic and therapeutic
strategies for asthma and other lung diseases. The program consists of course work, mentored
research experiences with esteemed pulmonary and genetics investigators, and preparation for the
submission of an NIH K08 application The goal of the Multidisciplinary Training in Asthma
Genetics and Genomics mechanism is to produce accomplished clinical/translational
researchers capable of utilizing the tools of clinical and/or basic research to improve the
understanding or treatment of human disease. Investigators must have a full time faculty-level
appointment; graduate students are not eligible. In addition, candidates are expected to assemble
a multidisciplinary mentoring committee of senior advisors/mentors. All Asthma Genetics and
Genomics Scholars are expected to complete classes in genetics and/or genomics offered at the
University unless they have already had equivalent training. Travel money is provided for scholars to
attend the NHLBI-sponsored ‘Genetic Approaches to Complex Heart, Lung and Blood Diseases’ once
during their training.
K12 Scholar Application and Review
Applicants must hold full-time appointment as regular faculty or research associate faculty at the
University of Chicago or other institutions, at the level of Instructor or Assistant Professor. To apply,
please e-mail the following to Lestra Cole by 06/30/11:
1. Your full curriculum vitae (not an NIH Biosketch)
2. A research proposal including Specific Aims, Background and Significance, Preliminary
Studies if any, and Research Design and Methods (limit 10 pages in all), plus Literature Cited.
Information regarding Human Subjects and Vertebrate Animal involvement should also be
included, as in NIH R01 applications. Literature Cited, Human Subjects, and Vertebrate
Animal sections are not included in the 10 page limit.
3. Individuals with a submitted/pending K-award application are not eligible to apply.
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4. A brief letter from the Department Chair addressing:
a. The candidate’s prospects for development into an independently funded
clinical/translational scientist
b. The Department’s assurance that at least 75% of the candidate’s time will be protected
for research career development and devoted to her/his role as a K12 Scholar
c. CTSA -The dollar amount requested for the candidate’s salary + fringe, not to exceed
$100,568 for the period 09/01/11 to 08/31/13, and percent effort to be devoted (must be
> 75%).
d. Paul Calabresi -The dollar amount requested for the candidate’s salary + fringe, not to
exceed $99,248 for the period 08/01/11 to 07/31/13, and percent effort to be devoted
(must be > 75%). Supply Budget up to $30,000.
e. Asthma Genetics and Genomics – The dollar amount requested for the candidate’s
salary + fringe, not to exceed $96,625 for the project period 7/01/11-6/30/13, and
percent effort to be devoted (must be 90%).
f. Names of the proposed mentors who will constitute a multidisciplinary mentoring
committee for the Scholar (a minimum of two disciplines must be represented)
5. A brief letter from the mentors, indicating their commitment to the candidate.
The NIH recognizes a unique and compelling need to promote diversity in the biomedical, behavioral,
clinical and social sciences workforce. Applications by women, underrepresented minorities,
individuals from disadvantaged background and individuals with disabilities remain a high priority for
funding. The academic and intellectual background, motivation, and commitment of the candidate to
pursue clinical and/or translational research will be evaluated. The criteria for selecting awardees will
include assessment of the candidate’s potential, the dedication to clinical and/or translational
research, and the degree of support from the Department. A crucial expectation of the awardees is
that preliminary data will be developed which will serve as the basis for an NIH-level grant application
in clinical and/or translational research. K12 Scholars are expected to establish a clinical/translational
research program, which can be sustained beyond the period of initial support.
K12 Scholars are expected to participate in the ITM’s Clinical Scholar Seminar Series and the ITM
Outcomes Research Workshops or Biological Translational Research Workshops, as appropriate to
their areas of study.
Application deadline is 06/30/11
Applications should be prepared as a single PDF file with filename as
CTSA-K12- PIname.pdf / Oncology-K12-PIname.pdf/Asthma –K12-PIname.pdf
Please e-mail applications (in a single PDF file) to Lestra Cole at:
lcole@bsd.uchicago.edu
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