CRGW Ltd: 07029220 EGG SHARING – INFORMATION FOR RECIPIENTS Screening Blood tests will be taken from you for: HIV Hepatitis B and C Rubella You will also need a pelvic scan. The Egg Provider A full personal and family medical history will be taken from the provider. They are advised that failure to disclose inheritable disorders about which they know or should reasonably have known could result in an affected child suing them in the future. Although the provider is screened for certain viruses, such as HIV, it is possible, that the laboratory may report a negative test when it may just not be able to detect a virus with the tests available. This is due to the nature of the tests and is unavoidable. Screening of the provider may reveal an unsuspected infectious or genetic condition and appropriate counselling and treatment would be arranged, this would also exclude them form proceeding with the arrangement. Counselling Prior to undertaking treatment, we will ask you / your partner to be seen by an independent counsellor who will explore ethical, and legal issues with you. Here she may discuss concerns regarding welfare of the child issues, including any feedback from the clinic meeting. It is important that you consider carefully all these before proceeding Ethical Issues You will be asked to consider the following issues; How you feel about having a child from donated eggs? What you will tell the child about his / her genetic origins? It is important that a child born from donor treatment be told about their origins in early childhood. There is evidence that finding out suddenly later can be emotionally damaging to children and family relations. The subject should be approached from an early age. The Donor Conception network provides four downloads on how to approach this with children at different ages. You should consider the needs of children born as a result of your decision to egg share, and the needs of any existing children now and in the future There is the possibility that children born as a result of this treatment could be unknowing siblings who in the future may live in the same geographical area. Document Name: PI 44 Egg Sharing – Info for Recipients Approved By: Umesh Acharya Author: Amanda O’Leary Version 3 (June 2013) Page 1 of 5 CRGW Ltd: 07029220 Legal Issues Since 1991 the Human Fertilisation and Embryology Authority (HFEA) has kept a confidential register about all sperm, egg and embryo donations. This includes a physical description, ethnicity and (if provided) occupation and interests. The register includes all treatments and resulting children. The following information can now be accessed; Donor-conceived individuals can receive: 18 year olds will be able to obtain: identifying information about the donor including name, address, date of birth and physical appearance if the donation was made after April 2005 Identifying information from donations made prior to April 2005 if the donor has retrospectively removed anonymity. Anonymous information if the donation was made before April 2005 and anonymity has not been removed Donor conceived offspring who intend to marry, or enter a civil partnership can submit a joint application to establish whether they are genetically related. Non-identifying information about their donor conceived genetically related siblings including number, sex and year of birth. 18 year olds will be able to find out identifying information about donor conceived genetically related siblings, if both sides consent, and will be able to find out identifying information about their donor, if applicable. 16 year olds will be entitled to: Non identifying information about their donor and their donor conceived genetically related siblings 16 year olds who intend to enter an intimate physical relationship can find out whether they are genetically related. Parents of donor-conceived individuals: Can be provided with non- identifying information about the donor by the clinic when they receive treatment Upon request the HFEA can provide them with the number, sex and year of birth of other offspring with the same donor. Donors Have the right to access the following anonymous information about their genetic offspring; number, sex and year of birth of people born as a result of their donation The HFEA is expected to contact and forewarn a donor of the fact that a donor conceived person has requested identifying information about him or her. Donors will be able to contact the clinic or the HFEA for this information Further Legal Issues Egg providers are allowed donate eggs which lead to the creation of a maximum of 10 families. The provider can restrict the use of her eggs to fewer than 10 families or place other restrictions on her consent. The egg provider may withdraw her consent to the agreement at any time before any eggs or embryos created form the treatment are transferred to you, used for research or allowed to perish. Document Name: PI 44 Egg Sharing – Info for Recipients Approved By: Umesh Acharya Author: Amanda O’Leary Version 3 (June 2013) Page 2 of 5 CRGW Ltd: 07029220 The outcome of the treatment cycles may be disclosed to the provider and recipient if both have consented. (This is up to the individual and we will respect your decision) Non identifying information may be given to you about the provider and we also encourage her to write a short biography which can be given to any child resulting from the arrangement. Egg providers have no legal claim to any children born from their donation. It is illegal for payment to be made as part of an egg sharing arrangement You will be the legal parent of any child resulting from donated eggs that have been fertilised and implanted in your womb. Medical Issues The provider may not produce enough eggs and this cannot always be anticipated as the ovary’s response to the stimulating drugs can vary from cycle to cycle. Potentially there is risk of over stimulation for the provider as we try to ensure enough eggs for all – this can result in serious complications for the provider, we are not prepared to take this risk and will plan treatment accordingly. Because the provider is sharing her eggs with you, there will not be many embryos available to freeze. Some embryos are unsuitable for freezing. There is a possibility that only one of the couples in an egg share arrangement may become pregnant. Information about the outcome of your cycle can be shared if you both consent. The implications of receiving information about the outcome of the treatment of person(s) with whom the eggs are shared, and allowing information about the outcome of one’s own cycle to be divulged need to be considered. In an egg sharing arrangement, both the egg provider and recipient have fertility problems and this should be considered, as the egg provider may have an undetected egg problem causing her infertility, which would therefore affect your embryos. As we are treating both the Egg Recipient and Egg Provider there is a potential conflict of interest because we are trying to do our best for both of you .We will ensure that this does not interfere with your clinical care and you will each be allocated a different nurse. If you feel that you have we have in any way treated you unfairly please discuss this with us. We would emphasise that neither you nor your egg provider should feel under pressure to go ahead with the treatment If the egg provider discovers a previously unsuspected genetic condition, the centre and the HFEA should be informed immediately, and consideration would be given to informing the egg recipient, the couples where there have been live births, and couples where pregnancies are on-going. In all circumstances the appropriate tests would be offered and counselling arranged. The Treatment Cycle This involves the provider undergoing a cycle of IVF and at the same time you take medication to prepare your womb for an embryo transfer. To allow synchronisation of your cycles you may need to commence either the oral contraceptive pill (if not contraindicated) or a progesterone tablet. If you have functioning ovaries we will initially “switch off” your hormones with daily injections to enable us to control your cycle. After 2-3 weeks you will be seen for a scan and then commence tablets to thicken up your womb lining. This usually takes about 2 weeks. At the same time, the donor will be undergoing stimulation to her ovaries. On the day of her egg collection your partner will be asked to produce a semen sample (unless donor sperm is used) The embryologist will inseminate the eggs and leave them in an Document Name: PI 44 Egg Sharing – Info for Recipients Approved By: Umesh Acharya Author: Amanda O’Leary Version 3 (June 2013) Page 3 of 5 CRGW Ltd: 07029220 incubator overnight. They are checked for fertilisation the following day. You will be contacted and given an appointment for an embryo transfer 2-5 days hours after the egg collection. You will continue your medication and do a pregnancy test 14-16 days after the embryo transfer. As with all fertility treatment there is a risk of ectopic pregnancy and multiple pregnancies. No more than two embryos can be replaced for you, irrespective of your age, as the eggs are derived from a donor of less than 36 years of age. To reduce the risks of multiple pregnancy we now encourage a single embryo transfer. If your womb lining does not become thick enough for embryo transfer at the appropriate time, we will freeze and store all the embryos that were created for your use and you can return for a subsequent attempt at a later date. Consents There are a number of consents and forms to complete before treatment can proceed. We will require a copy of your passport You will need to consent to enable us to keep your GP informed of your progress and to request information from them if there are any welfare of the child concerns. Welfare of the Child questionnaire Consent to Embryo Transfer ( female) Consent to use and storage of your sperm and embryos for your partners treatment ( male) If using donor sperm there will be additional consents concerning legal parenthood (see information sheet regarding using donor sperm) The egg sharing agreement The Egg Sharing Agreement NB. There is a separate consent form for the agreement and the following outlines its contents If the egg provider produces 8 or more eggs she will share 50% of them with you. If she produces an odd number, you will get the extra egg. If she gets less than 8 eggs, we believe that there are too few to share and she will have the option to either keep them all or donate them all to you. The egg provider can withdraw from the egg sharing programme at any time before the embryos have been transferred. If this happens we will find you another donor. If there are less than 8 follicles on day 10, the provider may choose to continue to egg collection and keep all the eggs for her own use. In these circumstances the provider is advised that she will not be suitable as an egg provider in the future. The cost of the drugs is to be borne by the recipient individually and not reimbursed in the above circumstances. Anonymity Neither you nor your egg provider will have any identifying information about the other and we will ensure that you attend the clinic on different days or times Document Name: PI 44 Egg Sharing – Info for Recipients Approved By: Umesh Acharya Author: Amanda O’Leary Version 3 (June 2013) Page 4 of 5 CRGW Ltd: 07029220 Divulging Information about Cycle Outcomes You can choose to make information about the outcome of your cycle available to the egg provider. This can be helpful emotionally and in planning future treatments, alternatively you may prefer not to divulge any information- we will respect your wishes. You may wish to receive information about the egg provider’s cycle outcome, if consent is given. Again you have the right to choose and we will respect your decision. Cycle for the Egg Recipient includes: ultrasound scan consultation counselling the provider’s IVF cycle the recipient’s embryo transfer cycle embryo freezing for one year The cycle cost DOES NOT include Drugs for the individual couples Additional procedures not included in usual IVF/ICSI package Embryo Freezing after the first year Semen analysis Male virology bloods Screening bloods for both partners For further information please see: DC Network National Gamete Donor Trust Document Name: PI 44 Egg Sharing – Info for Recipients Approved By: Umesh Acharya Author: Amanda O’Leary Version 3 (June 2013) Page 5 of 5