Dr Piers Patten’s publications
Patten, P.E.M., Chu, C.C., and Chiorazzi, N. Chapter 5.1 B-cell chronic lymphocytic leukemia/lymphoma in NonHodgkin Lymphomas: Advanced Diagnostics and Personalized Therapies. Carbone A, Younes A (Eds). Future
Medicine, London, UK. DOI: 10.2217/EBO.12.257 June 2013.
Patten, P.E.M., Chu, C.C., Albesiano, E., Damle, R.N., Yan, XJ., Kim, D., Zhang, L., Magli, A.R., Barrientos, J., Kolitz, J.E.,
Allen ,S.A., Rai ,K.R., Roa, S., Mongini, P.K., MacCarthy, T., Scharff, M.D. and Chiorazzi, N. IGHV unmutated and
mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of
biologic functions. Blood. 2012; 120(24): 4802-4811. PMID: 23071276
Chu, C.C., Zhang, L., Dhayalan, A., Agagnina, B.M., Magli, A.R., Fraher, G., Didier, S., Johnson, L.P., Kennedy, W.J.,
Damle, R.N., Yan, X.J., Patten, P.E.M., Teichberg, S., Koduru, P., Kolitz, J.E., Allen, S..L, Rai, K.R., Chiorazzi, N. Torque
teno virus 10 isolated by genome amplification techniques from a patient with concomitant chronic lymphocytic
leukemia and polycythemia vera. Mol Med. 2011;17: 1338-1348. PMID: 21953418
Buggins, A.G.S., Levi, A., Gohil, S., Fishlock, K., Patten, P.E.M., Calle, Y., Yallop, D., Devereux, S.Evidence for a
macromolecular complex in poor prognosis CLL that contains CD38, CD49d, CD44 and MMP-9. Br J Haematol.
2011;154 (2): 216-222. PMID:21569005
Bagnara, D., Kaufman, M. S., Calissano, C., Marsilio, S., Patten, P.E.M., Simone, R., Chum, P., Yan, X. J., Allen, S. L.,
Kolitz, J. E., Baskar, S., Rader, C., Mellstedt, H., Rabbani, H., Lee, A., Gregersen, P. K., Rai, K. R. Chiorazzi, N.A novel
adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease.
Blood 2011;117(20): 5463-72. PMID: 21385850.
Buggins, A.G.S., Pepper, C., Patten, P.E.M., Hewamana, S., Gohil, S., Moorhead, J., Folarin, N., Yallop, D., Thomas,
N.S.B., Mufti, G.J., Fegan, C., Devereux, S. Interaction with vascular endothelium enhances survival in primary
chronic lymphocytic leukemia cells via NF-B activation and de novo gene transcription. Cancer Research 2010;
70 (19): 7523-7533. PMID: 20736369.
Patten, P.E.M., Buggins, A.G.S., Richards, J., Wotherspoon, A., Salisbury, J., Mufti, G.J., Hamblin, T.J., Devereux, S. CD38
expression in chronic lymphocytic leukemia is regulated by the tumor microenvironment. Blood 2008; 111 (10):
5173-5181. PMID: 18326821.
Buggins, A.G.S., Patten, P.E.M., Richards, J., Thomas, N.S.B., Mufti, G.J., Devereux, S. Tumor-derived IL-6 may
contribute to the immunological defect in CLL. Leukemia 2008; 22 (5): 1084–1087. PMID: 17972945.
Patten, P.E.M., Devereux, S. Lymphoma diagnosis: An update. Clinical Medicine 2007 Vol 7 Issue 6 pp 620-624.
PMID: 18193715.
Richards, J., Yvonne Morgan, G., Pearce, L., Patten, P.E.M., Mufti, G.J., Devereux, S. Laser capture microscopy as a
tool for the assessment of lineage-specific chimaerism from archived blood and bone marrow films. British Journal
of Haematology 2007 Vol 136 Issue 4 pp 677-678. PMID: 17367416.
Patten, P.E.M., Devereux, S., Buggins, ASG. Effect of CD3/CD28 bead-activated and expanded T cells on leukemic B
cells in chronic lymphocytic leukemia. Journal of Immunology 2005 Vol 174 Issue 11 pp 6562-6563. PMID:
15905490.
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