The Socio-demographic Characteristics & Economic Impact of HIV/AIDS Using Different Econometric Measures in two Gov in Egypt *Alaa El Din Ghanaam (M.D) , Abeer Barakat, MD**, Soad M. El Sayed *** *Health and Human Program Director Health Economist & Director of General Department of policy and Strategies of STSP, MOH **Assistant Professor of Health Care Management and Health Economics, Public Health, Department, Faculty of Medicine, Cairo University. ***Public Health Research specialist, International Public Health Consultant. 1. Introduction HIV’s prevalence in Egypt is considered to be relatively low, with estimates around 0.02 percent of the general population, which is approximately 9,213 people, suffering from it. But preconditions for a wider epidemic exist, according to the UNAIDS office in Egypt. Egypt still faces several challenges in maintaining low prevalence of HIV/AIDS. Egypt also receives millions of tourists and refugees from countries with high HIV prevalence and/or illicit drug use rates. In addition, there are pervasive fears and stigmatization of HIV/AIDS and a lack of effective STI/HIV/AIDS education programs and other preventive measures, such as peer education and outreach and behavior change communications among at-risk groups, "Health Profile: Egypt". United States Agency for International Development (March 2008). Accessed September 7, 2008>]. In addition, an increase in the incidence of HIV-TB co-infection could add to the complexity of fighting both diseases in Egypt. "Health Profile: Egypt", United States Agency for International Development (March 2008). Accessed September 7, 2008]. In addition, there are high risk factors that create an ideal environment for the rapid spread of HIV. These factors such as Overpopulation, especially in the age bracket of 15–24 who constitute 50 percent of HIV patients, Poverty, Illiteracy in the general population particularly among women, weak health system despite huge infrastructures, Egypt has a very high level of Hepatitis C infection, a virus with similar modes of transmission to HIV, Most reported HIV cases are transmitted through unprotected heterosexual sex , 90% of Egyptian women who live with HIV were infected within marriage. Relationship between the Prevalence and Economy The impact of the HIV/AIDS epidemic on the economy has been a concern since the beginning of the pandemic. Studies show GNP growth could decrease by more than 1 percentage point for every 10 per cent HIV prevalence. According to a World Bank study of nine Arab countries, the current level of response to the epidemic will result in a fall in gross domestic product (GDP) of 30–40% over the coming years, leaving those countries under the poverty line.( 1 Jenkins, C. and Robalino, D.A., 2003, The Cost of Inaction.) Others take the view that HIV/AIDS has had little impact on the macro-economy so far. It is difficult to estimate empirically the effect of HIV/AIDS on economic performance since so many factors other than HIV/AIDS affect economic growth. If we add the economic value of health as an aspect of “economic welfare”, which by definition is not a matter of income alone, Empirical assessments of societies' willingness to pay to avert an adult death have found values ranging from about 75 to over 180 times per capita GDP (Jamison, Sachs and Wang, 2001). Therefore, the value attached to actual mortality changes can be large in relation to the size of conventionally measured trends in GDP. If we add the view of Egyptian economy and effect of global crisis in donations for Developing Countries, the outcome will get worse. 1.1 Poverty and Health in Egypt About one fifth (19.6%) of the Egyptian population lie in poverty, among them 3.8% of the population are in extreme poverty, Poverty is concentrated in the rural sector and in Upper Egypt where 77% and 62% of the poor are present, respectively. Out of the poor 55% work in agriculture and 9% work in construction, studies show that poor spend 2.9% of their total expenditure on health (LE 213) and 1.96% (LE 196) in education and Their expenditure on food is 54% (LE 3966). 1.2 Four Channels through which HIV/AIDS may Affect the Economy Authors identified four channels through which HIV/AIDS may affect the economy: the production channel; the allocation channel; the distribution channel; and the regeneration channel. The impact of HIV/AIDS on labor force becomes more eminent if it affects hard-toreplace skilled labor and/or if there is no substantial pool of “surplus labor”. Reducing the size of the working population tends to reduce total output and worsen the dependency ratio. HIV/AIDS reroutes some of those resources to medical expenses and away from other productive uses. The medication cost rises by time and differs among countries. In addition to HIV/AIDS epidemic that increases health expenditures and weakens the income base, the lowest income groups may fare the worst. If the HIV/AIDS epidemic compromises the saving capacity and the human capital of the economy, it will undercut the process of economic development. Foreign and domestic private investment might also decline if potential investors become convinced that the epidemic is seriously undermining the rate of return to investment (Theodore, 2001). Previous Research Concerning Economic Impact of HIV/AIDS in Egypt World Bank conducted the first attempt to evaluate the risks of an HIV/AIDS epidemic in 9 Middle East and North Africa (MENA) countries (Algeria, Djibouti, Egypt, Iran, Jordan, Lebanon, Morocco, Tunisia, and Yemen) and its potential economic costs (Robalino et al., 2002). According to the MENA study, the prevalence rates in Egypt in year 2015 would be between 3.8 percent in 16.1 percent. On average, GDP losses due to the projected prevalence for 2000- 2025 could approximate 44 percent of today's GDP. There, health expenditure on AIDS would represent 1.3 percent of GDP. Table (9), summarizes the distribution of the output variables of interest by reporting the mean, standard deviation, and the minimum and maximum values (Robalino et. al., 2002). The range of variation of the economic figures between Egypt and the other eight countries under study is similar (excluding Djibouti). The prevalence of HIV/AIDS in MENA countries in year 2015 would be between 0.3% and 17% (excluding Djibouti). Across countries, losses in the present value of GDP per capita could range between close to 2.3% of today's GDP to over 100% (in Djibouti maximum impacts could be equivalent to 7 times current GDP). Average real GDP growth rates for the period could be reduced by 0.02% to 2.7% per year. The size of the population in year 2025 could be reduced by 0.3% to 15%, and HIV/AIDS related expenditures could increase by 0.1% to 6% of GDP in year 2015 (Robalino etal., 2002). 3. Methodology of the study 3.1. Objectives of the Study 1- Study the socio-demographic profile of PLHA 2- Assess the economic condition of PLHA before and after infection 3- Identify the potential impact of HIV/AIDS at both macro and microeconomic level 3.2. Study Design: This study was a cross sectional study having descriptive and analytical elements and using both qualitative and quantitative methods. 3.3 Study Setting: This study included cases from Cairo and Alexandria governorates and from other Lower and Upper Egypt governorates. 3.4. Sample size and sampling technique: A sample of 25% of AIDS population in Egypt was selected in collaboration with the NAP for participation in the study. Sample selection will be done according to geographic distribution of cases, to represent rural/urban Upper and Lower Egypt and largest urban governorates, i.e. Cairo and Alexandria. Participants included PLHA, and their families, NAP managers and personnel in addition to and policy makers. Desk review was carried out for gathering data from available documents. 3.5. Study Tools: 1- In-depth interview (23 Questions covered 3 social, cultural and economic aspects) to NAP managers and personnel 2- In depth interview (27 questions covered economic, cultural, policies, planning and services, health expenditure) to PLHA and their families 3.6. Data Collection: Data were collected by direct interviewing with the study population. Multiple interviews, when necessary were organized for building trust and confidence with studied persons before data collection. Participation was voluntary, confidentiality was guaranteed and the objectives of the study were discussed. 3.7. Methods of Estimating the Economic Impact of HIV/AIDS 3.7.1 The Macroeconomic Impact a) Reviewing of literature to identify the mechanisms by which HIV/AIDS can affect the economy of a country. Economic assessment of some policy interventions are searched in literature. b) Estimation of the cost from the perspective of the MOHP/NACP - Total annual budget of NAP. - Items of expenditure of NAP budget. - Cost of case management. - Share of donors and private sector in covering AIDS expenses. c) Current output loss due to AIDS deaths: using the labor force percent out of total population the annual productivity of labor was calculated in LE. This was multiplied by the number of deaths in 2006. The product is further divided on 2006 GDP to estimate the potential output losses in year 2006. d) The treatment cost is also estimated. 3.7.2 The Microeconomic Impact - Pattern of income and expenditure before and after respondents' and spouses' infection. - Perceived types of changes in family situation after respondents' and spouses' infection. - Source of financing of the medication other than ARV - The cost of medical treatment from the perspective of the patient: Direct cost: is paid by the patient directly to the health care providers. Monthly cost of medications, special diet and lab investigations are added to calculate the direct cost. Indirect cost: the transportation costs and loss of previously earned income. 4. Results 4.1 Results related to the socio-demographic characteristic of the group Distribution of age groups by gender showed a statistically significant relation with a pvalue of 0.016 as shown in Figs. 1&2 Fig. 1. & Fig 2. Distribution of cases defined by sex & Distribution of cases defined by age group affected - Marital status by gender, demonstrating that the single status of women is more than men specially one third of the women are widowed and this doubles the socioeconomic burden on them. Table 1. Demonstrates the marital status of both male and female by % Gender Marital Status P Value* married never married divorced separated widowed Total Male 38.4% 22.4% 5.2% 2.0% .8% 68.8% .000 Female 13.6% .8% 2% 2.4% 12.4% 31.2% .000 Total 52% 23.2% 7.2% 4.4% 13.2% 100.0% .000 Table 2 .Demonstrates the literacy status for both males and females Education illiterate read&write,prim,prep secondary,tec.edu University &up Total P value Male 8.80% 20.00% 23.20% 16.80% 68.80% .419 Female 6.40% 8.40% 10.40% 6.00% 31.20% .433 % of Total 15.20% 28.40% 33.60% 22.80% 100% .174 Table 3. Demonstrates the Geographical Distribution by gender Geographical Distributions by gender Urban rural Total Male 35.60% 33.20% 68.80% Female 15.60% 15.60% 31.20% Total 51.20% 48.80% 100.00% ble : 4. Current Family and Social Condition “ is your wife live with you”? Answer Frequency % Yes 126 89.4% No 15 10.6% Total 141 100% Table 5. Did anyone live with you before having AIDS Answer Frequency % Yes 232 93% No 18 7% Total 250 100% Flowchart 1: Working status of respondents: Only 50% of all study participants are working now. Out of the working half 65.6% are at a professional job. Out of those not currently working 65% were working before. Most of the latter category left work due to being tired from illness or to stay home to care for an ill parent. These were mainly females (flowchart 2). Flowchart 2: Household existence of respondents' family members About two-thirds of the family members of the respondents are currently living with them. Those not living with the respondent left because of death which was mainly idiopathic or less commonly due to disease. Four of family members left for being affected by AIDS. Nine have left after respondents' disease to live with their families (flowchart 2). 4.2 Findings regarding the macroeconomic impact a. Financing of MOHP/NACP About LE50-60 Million are spent every year to cover preventive and curative services adopted by the MOHP/NACP. Of all AIDS cases 400 cases need treatment. The average medication cost is about LE3000 per case per month. This is apart from the medication costs of managing complications that include opportunistic infections, and from inpatient services expenses. Both costs are not estimated by the NACP. Annual analysis of about 1,200,000 blood samples which is done to screen HIV-infected cases costs about LE70-80 Million. The CD4 count is applied to all AIDS cases every 3 months. It costs LE250 per person. The NAP budget also covers the annual training of physician's in different specializations (NAP official, 2009). Real financial support from the private sector in Egypt is missing. According to the Global Fund Grants a fund of $11527830 is projected to cover anti-AIDS planned activities along two phases. Less than half the latter fund has been agreed. 4.3 Output loss due to AIDS Table 6 .Computing average productivity Year Population Labor force/population% (mn) (LE bn) Annual productivity of labour (LE) GDP 2001-2002 67.9 29.5% 379.0 19856.9 2002-2003 69.2 29.4% 417.5 20521.2 2003-2004 70.5 30.6% 407.0 18866.2 2004-2005 71.9 30.8% 425.2 19200.6 2005-2006 73.6 31.8% 454.3 19410.6 2006-2007 77.5 32.5% 744.3 29550.4 2007-2008 81.7 NA 798.1 NA Average productivity (2002-2006) LE 21234.3 Table 7. Potential output losses in LE due to AIDS losses Average productivity LE 21234.3 AIDS deaths in 2006 Potential output losses in 2006 High estimate Low estimate High estimate Low estimate 1144 1028 87315441.6 21828860.4 (0.0053% of GDP) (0.0048% of GDP) Average (%0.005 of GDP) b. Medication Cost Due to incomplete information we needed to resort to a better proxy of the medication cost i.e. the medication cost in other developing and comparable countries. Thus, for analytical purpose the average medication cost of Ethiopia and the Caribbean countries, which is 257 USD (2185 Birr) and 4000 USD respectively, was taken (Theodore, 2001; Zerfu, 2002). Table: 8. Medication Cost using the Ethiopian estimation (in USD) Infected Adult Medication Cost (USD) Average cost per adult 257 USD Medication cost related to HIV death (USD) Infected Adult Medication Cost Output loss *Scenario 1 2744 705208 (0.00089 % GDP) *Scenario 2 10757 2764549 (0.0034% GDP) HIV Death Medication Cost Output loss *Scenario 3 1028 264169 (0.00033% GDP) *Scenario 4 1144 294008 (0.00037% % GDP) * Scenario 1, assuming the NACP prevalence of the HIV (2009): 2744., * Scenario 2, assuming the WHO prevalence of the HIV (2009): 9213-12300 (av10757)., * Scenario 3, assuming the low estimate deaths of the HIV (2006): 1028. , * Scenario 4, assuming the high estimate deaths of the HIV (2006): 1144 Table 9. Medication Cost using the Caribbean Estimation (in USD) Infected Adult Medication Cost Average cost per adult 4000 USD Medication cost related to HIV death Infected Adult Medication Cost Output loss *Scenario 1 2744 10976000 (0.013% GDP) *Scenario 2 10757 43028000 (0.054% GDP) HIV Death Medication Cost Output loss *Scenario 3 1028 4112000 (0.0052% GDP) *Scenario 4 1144 4576000 (0.0057% % GDP) * Scenario 1, assuming the NACP prevalence of the HIV (2009): 2744. , * Scenario 2, assuming the WHO prevalence of the HIV (2009): 9213-12300 (av10757)., * Scenario 3, assuming the low estimate deaths of the HIV (2006): 1028. , * Scenario 4, assuming the high estimate deaths of the HIV (2006): 1144. A more intimate estimation would be done by using the NACP figure, namely, LE3000 per case per month (LE36000/year) (NAP official, 2009). Table 10. Medication Cost using NACP/WHO prevalence estimation (in LE) Infected Adult Medication Cost Average cost per adult LE36000/ year Medication cost related to HIV death Infected Adult Medication Cost Output loss *Scenario 1 2744 98784000 (0.0216% GDP) *Scenario 2 10757 387252000 (0.0852% GDP) HIV Death Medication Cost Output loss *Scenario 3 1028 37008000 (0.00816% GDP) *Scenario 4 1144 41184000 (0.00912% GDP) * Scenario 1, assuming the NAP prevalence of the HIV (2009): 2744., * Scenario 2, assuming the WHO prevalence of the HIV (2009): 9213-12300 (av10757)., * Scenario 3, assuming the low estimate deaths of the HIV (2006): 1028. , * Scenario 4, assuming the high estimate deaths of the HIV (2006): 1144. 4.4 Findings regarding the microeconomic impact Many responses describe the family financial deteriorating situation after respondents' infection; Level of expenditure reported by respondents after their spouses' infection has dramatically decreased. That is most likely due to the indicated reduction of both partners' work and income. This could be explained by decrease in physical ability and /or diverted time to care for one's ill spouse. In addition the money earned from other new sources of income, including NGOs, is mainly spent on treatment. Perceiving a change of family situation after spouse's infection was more evident among male than female respondents, 62.5% and 53.3%, respectively. However, social changes were more perceived by male respondents than financial ones, 60% and 20%, respectively. On the other hand, financial changes were more perceived among Upper Egypt respondents than social ones, 57.1% and 21.4%, respectively. Paying for the medication other than ARV was out of pocket in 100% of Upper Egypt, rural and female respondents. Average monthly cost of medications was LE 681.7+2112.7. The source of drugs is the pharmacy, the Liver Institute or Caritas NGO in 90.9%, 7.8% and 1.3%, respectively. About a third of respondents (31%) needed special food with an average monthly cost of LE 503.7+439.5. Some respondents (11.2%) needed to perform lab investigations with an average monthly cost of LE227.68+252.7. These are done mainly in governmental hospitals (83.6% of users) followed by private hospitals (7.1% of users). Table 11. Monthly direct costs of case treatment as reported by respondents Mean SD Median Inter-quartile range Min max 2408.2 4125.8 721 721 (383-1242.5) 240 11799 The values in table (11) were calculated by mere addition of the expenses reported by the respondents; medications, laboratory investigations and special diet. For three reasons these figures should be considered cautiously. First, this cost is identified from the patient's perspective, and not the MOH, the community or the health facility. Second, the statements of the patients might be underestimated as a trial to get more financial and medical support from the agencies conducting the interview. Third, some of the cost items were not recorded, e.g. the physician fee, the hospital admission costs and the transportation costs. Also, indirect costs related to loss of previously earned income were not thoroughly investigated. 4.5 Economic Assessment of Policy interventions in Literature Reducing risks (through information and preventive behaviors and services) in those population groups most likely to contract and spread HIV can be highly cost-effective (Kahn, 1996). Interventions such as reproductive health and HIV/AIDS education in schools, targeted STD treatment for highly vulnerable groups, and harm reduction for IDUs have also proved to be cost-effective (Jenkins, 2002). Expanding condom use and access to clean needles for intravenous drug users GDP losses during the period 2000-2025 would be significantly reduced, by an equivalent of 27% of 2002 GDP in the case of Egypt. Delaying action for five years can cost, on average, the equivalent of six percentage points of today's GDP (Robalino et. al., 2002). Conclusion: The risk of an increase in the HIV/AIDS prevalence rate in Egypt is real and the expected costs over the next 25 years could be considerable specially the poor are more exposed to infectious diseases and complicated with malnutrition, and thus are more vulnerable to the deterioration of their immune system. They are already face problems of Access to health services as health systems become financially constrained, these problems can be exacerbated. At the same time, there are actions that can be implemented to prevent the spread of the epidemic and the costs of these actions would be more than compensated by the savings they generate; and the time to act is sooner better than later especially when prevalence rates are still low. References: World Report on the Global AIDS Epidemic 2008 UNAIDS. National HIV/AIDS Control Program ( 2009 ) , National l HIV/AIDS Statistics 2008/2009, MOH ,Egypt. Zerfu Daniel, 2002. The Macroeconomic Impact of HIV/AIDS in Ethiopia. Department of Economics, Addis Ababa University. Bloom D. and Mahal A. 1995. "Does the AIDS Epidemic Really Threaten Economic Growth?". Working Paper No. 5148. National Bureau of Economic Research. Bonnel Ren6. 2000. "HIV/AIDS: Does it Increase or Decrease Growth?". Forthcoming South African Journal of Economics. Bollinger L. , Stover J. and Nalo D. 1999. "The Economic Impact of AIDS in Kenya". Over M., Mujinja P., Dorsainvil D., and Gupta 1. 1999. "Impact of Adult Death on Household Expenditures in Kagera, Tanzania." Working Paper. World Bank, Policy Research Department, Washington, D.C. Soucat Agnes. 2001. "Economic Analysis of High Fertility and HIV/AIDS in Chad". World Bank. Chad. Ellis, Randall, Alam, Moneer, and Gupta, Indrani. Health Insurance in India: Prognosis and Prospectus. Boston University, Boston. Massachusetts, 1997 (unpublished manuscript). Over M. 1992. "The Macroeconomic Impact of AIDS in Sub-Saharan Africa". Working Paper. Population and Human Resources Department. The World Bank. Leighton C. 1993. "Economic Impacts of the HIV/AIDS Epidemic in African and Asian Settings: Case Studies of Kenya and Thailand". Abt. Associates. Bethesda, MD. Nalo D and Aoko M. 1994. "Macro Economic Impact of HIV/AIDS in Kenya". Nairobi. MacFarlan Maitland and Sgherri Silvia. 2001. "The Macroeconomic Impact of HIV/AIDS in Botswana". IMF Robalino, David, Jenkins Carol, and El Maroufi Karim. 2002. The risks and macroeconomic impact of HIV/AIDS in the Middle East and North Africa. Why waiting to intervene can be costly. Working paper. The World Bank Middle East and North Africa Region -Human Development Group. Kahn J. 1996. "The Cost-Effectiveness of HIV Prevention Targeting: How much more bang for the buck". American Journal of Public Health. 86 (12): 1709-12. Abdelmawla S.: A simplified reading of the national budget in Egypt for FY 2008/09 in website www.socialcontract.gov.eg (December, 2008) EHHUES: Egyptian household health utilization and expenditure survey, 2002., Egypt National Health Accounts 2001-02. Partners for Health Reformplus 2005. Department of Planning and Finance, Ministry of Health and Population.