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July 15, 2005
B I O T E C H S Y S T E M S, I N C.
Market Research in the Health Care Field
4167 Pinecrest Circle West
Las Vegas, Nevada 89121
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(702) 456-7608 (702) 456-2189 FAX
E-Mail: biotechsystems@earthlink.net
Web Site: www.biotechsystems.com
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FOR IMMEDIATE RELEASE Contact: Marvin Burns
Tel: (702) 456-7608
Fax: (702) 456`-2189
BIO-TECH SYSTEMS ANNOUNCES THE RELEASE OF A NEW PET REPORT:
Report 220: MARKET FOR PET RADIOPHARMACEUTICALS AND PET IMAGING
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PRESENT AND EMERGING MARKETS FOR PET IMAGING, INCREASE IN FDG SALES,
U.S AND WORLDWIDE MARKETS FOR PET SCANNERS, MARKET IMPACT OF PET-CT,
NEW MOLECULAR TRACERS FOR PET, CONTINUED GROWTH IN INTERNATIONAL
SALES, TECHNOLOGICAL TRENDS AND SALES FORECASTS TO 2010
Bio-Tech Systems Inc. announces the publication of a comprehensive report analyzing the markets for PET radiopharmaceuticals and PET imaging. This includes the rapid growth of
FDG sales and expanding markets in oncology as well as cardiology and neurology, with detailed analysis of opportunities in each area. The report covers the US and worldwide markets for PET scanners, indicating the sales growth and dominance of PET-CT over dedicated PET. Growth is also continuing in the international market for PET as the technology becomes more readily available and the distribution of FDG improves. The report analyzes each of the market segments including mobile PET, which has continued to attract well-financed and capable companies in the field. The report also discusses PET procedure volume by disease category with forecasts of future growth in lung cancer, breast cancer, lymphoma, colon cancer, melanoma and other cancers where PET has shown its effectiveness.
The report has a strong focus on new products and technology and emerging market opportunities. The overlap between PET and radiology, which was stimulated by the success of combined PET-CT systems, has allowed radiologists to promote the advantages of multimodality imaging to both patients and investors in PET imaging facilities. As the availability of
PET increases and its capabilities become more visible to referring physicians, it will encourage procedure growth in oncology as well as cardiology and neurology. Continued approval of new indications for PET, including Alzheimer's disease, is certain to stimulate procedure growth.
New PET radiopharmaceuticals are also in the pipeline that will measure biochemical processes that show patient response to therapy. This will overcome some of the limitations of conventional FDG-PET and allow measurement of cellular response to therapy rather than metabolism. This will aid in treatment monitoring and therapy planning for breast cancer, prostate cancer, brain cancer, bone cancer, and other common cancers.
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GROWTH OF PET PROCEDURE VOLUME AND SALES OF FDG
The demand for PET continued to grow in 2004 reaching 1 million procedures, an increase of
46% for the year. Growth should continue with procedure volume increasing 37% in 2004. By
2010, PET procedure volume should rise to 3.2 million procedures. Approval of new indications in oncology have added to procedure volume as well as expanded use of PET in lung cancer, breast cancer, colon cancer, lymphoma and melanoma. Although the dominant focus of PET is still in oncology, cardiology applications have increased in diagnosing myocardial viability and follow-up to equivocal SPECT studies. This has been stimulated by the introduction of PET-CT with multi-slice configurations suitable for cardiac imaging. PET has become more accessible to a wider base of physicians and patients, increasing the referral base. This has stimulated sales of FDG, while reducing the cost per dose. FDG sales of $270 million in 2004 were up 34% from $202 million in 2003. These sales should reach $795 million by 2010, notwithstanding the diminishing price per dose for FDG. These estimates are conservative and are based on present utilization. It is likely that new indications in oncology and cardiology as well as neurology will add further stimulus to the market for PET and FDG.
SALES GROWTH OF PET IMAGING SYSTEMS
In 2004, there were 296 PET scanners sold domestically and 531 scanners sold worldwide. US sales were $481.5 million and worldwide sales were $882.0 million. Domestic sales increased
13.5% from the previous year and worldwide sales increased 31.1%. This continued growth in
PET orders is encouraging notwithstanding the excess equipment capacity as users attempt to increase the referral base. International sales have increased rapdily with growth rates higher than the US. This reflects growing awareness of PET and expanded reimbursement, particularly in Japan. Both US and international users have adopted PET-CT very rapidly. In
2004, PET-CT comprised about 95% of total billings. By 2010, domestic bookings will increase to 555 units with sales of $916 million. Worldwide bookings will reach 1,100 units and $1,870 million in sales volume. The proportion of international sales will continue to rise from 45% in 2004 to 50% or higher by 2010. In 2004, 26% of all PET scanners sales were mobiles, comprising $126 million in sales. This level of activity should continue, with mobile sales providing an important underpinning in the PET market.
ABOUT THE AUTHOR
Marvin Burns is president of Bio-Tech Systems, Inc., founded in 1980 to perform market research for companies in the healthcare field. Burns specializes in market evaluation, where technological and scientific insight is important. He has prepared numerous reports on PET that have been widely distributed. He also reports on the markets for diagnostic and therapeutic radiopharmaceuticals, brachytherapy products, contrast agents, interventional cardiology and cardiac imaging. Burns has served as a consultant to many international firms and venture groups in strategic planning and development of new business opportunities. He has also been
Technology Editor of Future Oncology, a publication widely circulated in the pharmaceutical and biotechnology industry, reporting on new developments in cancer diagnosis and treatment.
Burns is a graduate of MIT and Harvard Business School’s advanced management program.
He has over 100 publications and 15 patents and invention disclosures. Prior to forming
Bio-Tech Systems, he was employed by firms in life sciences, bioinstrumentation and medical imaging fields in general management, marketing and product development. He was also a hospital administrator in charge of professional and technical services including medical imaging, clinical laboratories, therapy services, and materials management.
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THE MARKETFOR PET IMAGING: REPORT CONTENTS
SECTION I: PET Market Overview
Analysis of recent sales growth, competitive challenges and future prospects for PET.
Discussion of new indications for PET and effect on market growth. The topics include:
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Growth of primary applications for PET in oncology, cardiology and neurology. Effect of expanded indications on sales of FDG and PET scanner sales.
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Overview of PET scanner sales and effect of new products, particularly high throughput scanners and combined PET-CT systems.
SECTION II: Growth of PET Procedure Volume
Driving forces affecting growth of PET procedures. Historic and forecast PET procedure volume in oncology, cardiology and neurology, by disease group.
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Distribution of PET procedures by disease group. Forecasts of procedure volume growth in lung cancer, breast cancer, lymphoma, colon cancer, melanoma and other cancers.
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Discussion of PET reimbursement and expanded indications in oncology. Prospects for continued growth of PET procedures.
SECTION III: Analysis of the FDG Market
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Historic and forecast sales growth of FDG by application and disease group.
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Analysis of FDG suppliers and challenges in producing and delivering FDG.
Competitive prospects, pricing pressures and growth of new companies supplying FDG.
SECTION IV: US and Worldwide Market for PET Scanners

Distribution of PET sales by manufacturer; Siemens, CTI, GE, Philips and Positron
Corporation. Discussion of marketing strategies and future outlook.
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Product mix of fixed site and mobile scanners. Pricing trends and competitive strategies of PET manufacturers.
SECTION V: US AND Worldwide PET Sales Forecasts
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US and worldwide sales forecasts for PET scanners by type of installation including fixed site and mobile PET systems.
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Analysis of the market environment for future growth of PET, both US and internationally. Discussion of new products, technological prospects and user demand.
SECTION VI: Growth of US and Worldwide Installed Base
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US and worldwide forecasts of installed base from 2000-2010. Rationale underlying the growth of installed base in all product categories.

Changes in market environment that may affect growth of installed base.
SECION VII: End-User Profile
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Analysis of end-user groups and comparative requirements for PET imaging.
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Procedure mix and product utilization in hospitals and clinics. Allocation of imaging procedures and equipment by hospital bed size.
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PARTIAL LIST OF EXHIBITS─MARKET FOR PET IMAGING
HISTORIC AND FORECAST PET
PROCEDURE VOLUME FOR
CARDIOLOGY, NEUROLOGY AND
ONCOLOGY FROM 2000-2010
HISTORIC AND FORECAST PET
PROCEDURE VOLUME IN ONCOLOGY
BY TYPE OF DISEASE FROM 2000-2010
HISTORIC AND FORECAST SALES OF
FDG DOSES FOR CARDIOLOGY,
NEUROLOGY AND ONCOLOGY FROM
2000-2010
HISTORIC AND FORECAST SALES OF
FDG FOR ONCOLOGY APPLICATIONS
BY DISEASE TYPE FROM 2000-2010
US DISTRIBUTION OF COMMERCIAL
FDG SUPPLIERS. IN 2004, NUMBER OF
DISTRIBUTION SITES AND USER BASE
U.S. SALES OF PET FROM 2001-2004,
MANUFACTURER’S UNIT SALES AND
MARKET SHARE
U.S. SALES OF PET SCANNERS FROM
2001-2004, MANUFAC-TURER’S SALES
VOLUME AND MARKET SHARE
WORLDWIDE SALES OF PET
SCANNERS FROM 2001-2004,
MANUFACTURER’S UNIT SALES AND
MARKET SHARE
WORLDWIDE SALES OF PET
SCANNERS FROM 2001-2004,
MANUFACTURER’S SALES VOLUME
AND MARKET SHARE
U.S. SALES OF MOBILE PET SCANNERS
FROM 2001-2004, MANUFACTURER’S
UNIT SALES AND MARKET SHARE
U.S. SALES OF MOBILE PET SCANNERS
FROM 2001-2004, MANUFACTURER’S
SALES VOLUME AND MARKET SHARE
DISTRIBUTION OF MOBILE PET UNITS
AMONG MOBILE PET PROVIDERS,
UNITS PURCHASED BY EACH MOBILE
PET COMPANY FROM 2000-2004
HISTORIC AND FORECAST U.S. UNIT
SALES OF PET SCANNERS FROM
2000-2010
HISTORIC AND FORECAST U.S. SALES
VOLUME OF PET SCANNERS FROM
2000-2010
HISTORIC AND FORECAST U.S. SALES
OF MOBILE PET SCANNERS,
MANUFACTURER’S UNIT SHIPMENTS
AND SALES VOLUME FROM 2000-2010
HISTORIC AND FORECAST
WORLDWIDE UNIT SALES OF PET
SCANNERS AND COINCIDENCE
CAMERAS FROM 2000-2010
HISTORIC AND FORECAST
WORLDWIDE SALES VOLUME OF PET
SCANNERS AND PET GAMMA
CAMERAS FROM 2000-2010
GROWTH OF U.S. INSTALLED BASE OF
PET SCANNERS AND CAMERA-BASED
PET SYSTEMS FROM 2000-2010
GROWTH OF MOBILE PET INSTALLED
BASE IN THE U.S FROM 2000-2010
GROWTH OF WORLDWIDE INSTALLED
BASE OF PET SCANNERS AND
CAMERA-PET FROM 2000-2010
PET PROCEDURE VOLUME BASED ON
SCANNER UTILIZATION IN 2004
2004 NUCLEAR CAMERA SHIPMENTS,
INSTALLED BASE AND REPLACEMENT
RATES FOR NEW AND REFURBISHED
CAMERAS IN HOSPITALS AND
IMAGING CLINICS
COMPARATIVE UTILIZATION
PARAMETERS FOR DIFFERENT
IMAGING MODALITIES IN 2004
RELATIVE PROCEDURE VOLUME
AMONG DIFFERENT IMAGING
MODALITIES, PERCENTAGE BY
HOSPITAL BED SIZE IN 2004
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ORDER FORM
Report No. 220 - MARKET FOR PET RADIOPHARMACEUTICALS AND PET IMAGING
The report is priced at $7,500 including postage and handling..
Please make check payable to: BIO-TECH SYSTEMS, INC.
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BANK OF AMERICA, NEVADA
Post Office Box 98600
Las Vegas, Nevada 89193-8600
Routing/ABA #122 400 724
For credit to: BIO-TECH SYSTEMS, INC.
Account No. 270 113 178
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BIO-TECH SYSTEMS, INC.
4167 W. Pinecrest Circle
Las Vegas, Nevada 89121
Telephone: (702) 456-7608 FAX (702) 456-2189
E-Mail: biotechsystems@earthlink.net