
Design and Synthesis of New Organic NonLinear Optical Materials
Study of Reaction Mechanisms
Mechanistic
studies
of
novel
molecular
reorganizations encountered in the course of total
synthesis.
Representative Publications

Srinivasan Chandrasekaran
Professor and Chairman,Division of
Chemical Sciences; Ph.D. Madras
Univ. (with S. Swaminathan); Postdoctoral
research: Harvard University (with E.J.
Corey) and Syntex, Palo Alto. S.S.
Bhatnagar Prize (CSIR), FASc, FNA,
FTWAS
Tel: 293-2404; 360-2423 (off); 360-1269
(home) Fax: 360-0529/360-0683
E-mail:scn@orgchem.iisc.ernet.in
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Research interests
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New Synthetic Methodology:
Chemistry of Titanium (III) Tetrahydroborates
and their use in Stereoselective Reduction
Chemistry of Binary Molybdenum-Sulfur
Systems as Efficient Sulfur Transfer Reagents.
Development of New Protective Groups for
Peptide Synthesis using Mo-S Systems.
Study of Induced Internal Redox Reactions of
Tetrathiomolybdates.
New Ruthenium (II) –Bisoxazoline Catalysts
for
Highly
Chemoselective
Aerobic
Epoxidation and for Asymmetric Oxygen
Transfer Reactions.
Nanostructured Amorphous Metals / Alloys as
New Catalysts for Cycloalkane Oxidation.
Hybrid Organic –Inorganic Chiral Catalysts for
Asymmetric Synthesis
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Total Synthesis of Natural Products
Application of the reagents and synthetic
methodology developed in this laboratory to the
synthesis of natural products particularly Cyclic
Peptides, Pyrrolo Benzodiazepine class of AntiTumor Antibiotics, Carbohydrates etc.

S 2
S
O
S
N Cl N
O
Ru
Mo
Organic Materials
Design and Synthesis of Metallorganic
Chemical Vapor Deposition Precursors for
Thin Film Applications.
K.R.Prabhu,
N.Devan
and
S.
Chandrasekaran,
Chemistry
of
Tetrathiomolybdate:
Applications
in
Organic Synthesis, Synlett, 2002, 17621778
R.G.Bhat, S.Sinha and S.Chandrasekaran,
Propargyloxycarbonyl (Poc) Amino Acid
Chlorides as Efficient Coupling Reagents
for the Synthesis of 100% Diastereopure
Peptides
and
Resin
Bound
Tetrathiomolybdate as an Effective
Deblocking Agent For
Poc Group.,
Chem.Comm. 2002, 812-813
N. Devan, P. Ramu Sridhar, K.R. Prabhu
and
S.
Chandrasekaran,Tetrathiomolybdate Assisted Ring Opening of
Epoxides and Cleavage of Diselenides:
Multistep Reactions in One Pot,
J.Org.Chem.,. 2002, 67, 9417-9420.
P. Ramu Sridhar, K.R. Prabhu and S.
Chandrasekaran, Selective Reduction of
Anomeric Azides to Amines with
Tetrathiomolybdate: Synthesis of beta-DGlycosylamines, J.Org.Chem., 2003, 68,
5261-5264.
K. Shalini, G.N. Subbanna, S.A.
Shivashankar and S. Chandrasekaran,
Thin Films of Iron Oxide by Low Pressure
MOCVD Using a Novel Precursor: Tris( tButyl-3-oxo-butanoato) Iron (III), Thin
Solid Films, 2003, 424, 56-60.
D. Dhar, Y. Koltypin, A. Gedanken and S.
Chandrasekaran; Catalytic aerobic
epoxidation of olefins with
nanostructured amorphous CoO-MCM 41
prepared by ultrasonically controlled
deposition - precipitation of an
organometallic precursor., Catal.Lett.,
2003, 197-200
S
O
N Cl N
O