Research Organization
profile form
Date 2007
June
ORGANISATION
LOGO
Valid until: 2013
December
CONTACT DETAILS
Organisation
Name (full
name)
Organisation
acronym
(Abbreviation)
Address
Postal code
City
Country
www address
University ABOU BEKR
BELKAID of TLEMCEN
Contact person:
U. ABB. TLEMCEN
Title
Professor
IMAMA, BP 119
13 000
TLEMCEN
ALGERIA
www.univ-tlemcen.dz
First Name
Family Name
Telephone
Fax
E-mail
Hafida
MERZOUK
078449150
043207328
Hafidamerzouk_2@hot
mail.com
ORGANISATION TYPE
Research
Organisation
type
Research Organisation ( Private
Public X )
High Education School / University / Institute ( Private
Public X )
Other (e.g. research centre etc.), please specify:
Description of the organisation : your R&D activities, your specializations, your researchers etc.
(max 1.000 characters):
The main theme of our research is to elucidate the role of functional food such as dietary fatty acids
or newly synthesized organic molecules in lipoprotein metabolism, oxidant/antioxidant status and
T-cells activation which might be involved in the pathology of several diseases like diabetes and
obesity. We are studying now obesity, on multidisciplinary approaches including genetics, life style,
epidemiology, nutrition and physiology. Special attention is given to infantile obesity and early
marks of oxidant stress, accounting for an increased risk of adult metabolic diseases. Dietary
managements are proposed to prevent metabolic alterations related to infantile obesity.
EXPERTISE
Description of the
expertise that your
organization can
contribute with to a
European research project
(max 2.000 characters)
Lipoprotein metabolism, oxidant stress, nutritional survey, physiology and
physiopathology involved in metabolic diseases like diabetes, obesity,
atherosclerosis, HTA.
Aging and metabolic alterations
Utilization of animal models of diabetes and obesity.
Nutrition and health
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Indicate the expertise you ACTIVITY 1: Sustainable production and management of biological
can offer in the 3 following resources from land, forest and aquatic environments:
areas of activity:
Biological resources
Novel feeds
(you can indicate more than
Biodiversity
Novel plants
one)
Genomics/Proteomics/Metabolomics
Plant Health
Bioinformatics
Animal Production and Welfare
Agriculture
Animal husbandry
Forestry
Vaccines and Diagnostics
Fisheries
Organic production methods
Aquaculture
Dairy Production
Horticulture
Tracking and tracing
ACTIVITY 2: Fork to Farm: Food, health and well being
Consumer behaviour
X Functional Food
X Nutrition Science
X Physiology
Food Technology
Food Processing
Packaging
Food safety
Potable/Safe Drinking Water
Animal Feed
Chemical Food Safety
Microbiological Food Safety
New detection methods
Risk Assessment
Food Chain Analysis/Management
Pesticide/BioActive Additives /
…..Substances Control
ACITIVTY 3: Life sciences and biotechnology for sustainable non-food
products and processes
Biomass production
Bio-products
Bio-refinery
Bio-processes
Fibres (wool, cotton, novel-bio-fibres)
Wood-production
Pollution
Ecology
Waste Processing
COMMITMENT (of your organization to a European research project)
Term of your commitment
Short (< 1 year) X Medium (1 to 3 years)
Long (more than 3 years)
Type of your commitment
X Participation in research activities
Demonstration / Validation of technologies
Provision of training in areas of expertise
Provision of a technology needed for the project
Dissemination of project results
Other:
EXPECTATION (of your organization from the participation in a European research project)
Expected results for your
organisation (max 500
characters)
(Describe your project idea,
your project objectives or
your role in a research
Infantile obesity is associated to several metabolic alterations including
dyslipidemia, immune dysfunction and oxidant stress. Nutritional
survey, lipoprotein metabolism assessment and determination of
oxidant/antioxidant markers are necessary to improve our knowledge on
obesity and to propose nutritional preventive strategies against this
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project)
ORGANISATION
LOGO
metabolic disease.
The crucial question is whether n-3 PUFA supplementation can prevent
or ameliorate lipoprotein profile, immune function and
oxidant/antioxidant status in obese children. Could supplementation of
diet with n-3 PUFA during childhood exert beneficial effects in treating
the long term complications of obesity? Indeed, Could antioxidant
supplementation (vitamin, mineral) during childhood exert beneficial
effects in oxidant/antioxidant balance.
Further research is needed to establish the beneficial effects of n-3
PUFA and antioxidant supplementation in obese children.
INTERNATIONAL COOPERATION
Former participation in
National initiatives or
projects?
Former participation in
International research
projects?
Former participation in
European projects?
If YES:
Programme name:
Project title / acronym:
Activities performed:
Knowledge on the
European Framework
Programme on Research
and Development (FP)?
(The European funding
programme for research)
Interested in participating
in FP7 (2007-2013)?
Interested in receiving
training on FP7 issues?
X YES
NO
X YES
NO
YES
X NO



X YES
NO
X YES
NO
X YES
NO
PUBLICATIONS
List any
publications of
your organization
in the targeted
research topic
MERZOUK H., MEGHELLI-BOUCHENAK M., LOUKIDI B., PROST J.,
BELLEVILLE J. (2000). Impaired serum lipids and lipoproteins in fetal
macrosomia related to maternal obesity. Biology Neonate. 77: 17-24.
MERZOUK H., MEGHELLI-BOUCHENAK M., LOUKIDI B., MADANI S.,
PROST J., BELLEVILLE J. (2000). Fetal macrosomia related to maternal
poorly controlled diabetes strongly impaired serum lipoprotein concentrations
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and compositions. J. Clinical Pathology. 53:917-923.
MERZOUK H., KHAN NA. (2003). Macrosomia in diabetic pregnancy : what
role of metabolism of lipids ? Clin Scien. 105: 519-529
MERZOUK S, HICHAMI A, MADANI S, MERZOUK H, BEREOUIGAT A,
PROST J, CHABANE-SARI N, KHAN NA. (2003). Antioxidant status and
levels of different vitamins determined by high-performance liquid
chromatography in diabetic subjects with multiple complications. j. Gen.
Physiol. Biophys. 22 :15-27
GUERMOUCHE B, YESSOUFOU A, SOULIMANE N, MERZOUK H,
MOUTAIROU K, HICHAMI A, KHAN NA (2004) n-3 fatty acids modulate
T-cell calcium signaling in obese macrosomic rats. Obes Res. 12: 1744-1753
SOULIMANE-MOKHTARI N, GUERMOUCHE B, YESSOUFOU A,
SAKER M, MOUTAIROU K, HICHAMI A, MERZOUK H, KHAN NA
(2005) Modulation of lipid metabolism in gestational diabetic rats and their
macrosomic offspring. Clin. Scien. 109: 287-295
YESSOUFOU A, N SOULAIMANN N, MERZOUK SA, MOUTAIROU K,
AHISSOU H, PROST J, SIMONIN AM, MERZOUK H, HICHAMI A,
KHAN NA (2006) N-3 Fatty acids modulate antioxidant status in diabetic rats
and their macrosomic offspring. International Journal of Obesity 1 - 12
BABA AF, MEDJAHED W, MERZOUK H, KAJIMA MJ, BELLEVILLE J,
PROST J (2006) Effects of N-acyl-2-hydroxymethyl aziridines on in vitro
proliferative responses of human lymphocytes stimulated by mitogens. j. Gen.
Physiol. Biophys. 25: 277-287
What skills/results do you
expect from this
collaboration?
Main difficulties and
constraints to participate
in European projects?
Improve our knowledge on metabolic alterations associated to infantile
obesity, including lipoproteins, immune function and
oxidant/antioxidant status.
Participate to nutritional preventive strategies against infantile obesity
in order to reduce its prevalence and its long term consequences.
Difficulties to find EU partners or participants from abroad who share
our idea for a research project and with which we can cooperate.
Additional comments
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I agree with the publication of my data!
Please fill-in in English and return to:
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ORGANISATION
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